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4ERF
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crystal structure of MDM2 (17-111) in complex with compound 29 (AM-8553)
分子名称: E3 ubiquitin-protein ligase Mdm2, {(3R,5R,6S)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-[(2S,3S)-2-hydroxypentan-3-yl]-3-methyl-2-oxopiperidin-3-yl}acetic acid
著者Huang, X.
登録日2012-04-20
公開日2012-05-23
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure-based design of novel inhibitors of the MDM2-p53 interaction.
J.Med.Chem., 55, 2012
4ERG
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BU of 4erg by Molmil
Evidence for a Dual Role of an Active Site Histidine in alpha-Amino-beta-Carboxymuconate-epsilon-Semialdehyde Decarboxylase
分子名称: 2-amino-3-carboxymuconate 6-semialdehyde decarboxylase, FE (III) ION
著者Huo, L, Fielding, A.J, Chen, Y, Li, T, Iwaki, H, Hosler, J.P, Chen, L, Hasegawa, Y, Que Jr, L, Liu, A.
登録日2012-04-20
公開日2012-08-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.789 Å)
主引用文献Evidence for a Dual Role of an Active Site Histidine in alpha-Amino-beta-Carboxymuconate-epsilon-Semialdehyde Decarboxylase
Biochemistry, 51, 2012
4ERH
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BU of 4erh by Molmil
The crystal structure of OmpA domain of OmpA from Salmonella enterica subsp. enterica serovar Typhimurium str. 14028S
分子名称: GLYCEROL, Outer membrane protein A, SULFATE ION
著者Tan, K, Wu, R, Jedrzejczak, R, Adkins, J, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Program for the Characterization of Secreted Effector Proteins (PCSEP)
登録日2012-04-20
公開日2012-05-02
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献The crystal structure of OmpA domain of OmpA from Salmonella enterica subsp. enterica serovar Typhimurium str. 14028S
To be Published
4ERI
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BU of 4eri by Molmil
Evidence for a Dual Role of an Active Site Histidine in alpha-Amino-beta-Carboxymuconate-epsilon-Semialdehyde Decarboxylase
分子名称: 2-amino-3-carboxymuconate 6-semialdehyde decarboxylase, MAGNESIUM ION, ZINC ION
著者Huo, L, Fielding, A.J, Chen, Y, Li, T, Iwaki, H, Hosler, J.P, Chen, L, Hasegawa, Y, Que Jr, L, Liu, A.
登録日2012-04-20
公開日2012-08-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.0006 Å)
主引用文献Evidence for a Dual Role of an Active Site Histidine in alpha-Amino-beta-Carboxymuconate-epsilon-Semialdehyde Decarboxylase
Biochemistry, 51, 2012
4ERJ
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BU of 4erj by Molmil
Crystal structure of the lysine riboswitch bound to a 6-aminocaproic acid
分子名称: 6-AMINOHEXANOIC ACID, Lysine riboswitch RNA
著者Garst, A.D, Porter, E, Batey, R.T.
登録日2012-04-20
公開日2012-07-18
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Insights into the regulatory landscape of the lysine riboswitch.
J.Mol.Biol., 423, 2012
4ERK
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BU of 4erk by Molmil
THE COMPLEX STRUCTURE OF THE MAP KINASE ERK2/OLOMOUCINE
分子名称: EXTRACELLULAR REGULATED KINASE 2, OLOMOUCINE, SULFATE ION
著者Wang, Z, Canagarajah, B, Boehm, J.C, Cobb, M.H, Young, P.R, Abdel-Meguid, S, Adams, J.L, Goldsmith, E.J.
登録日1998-07-09
公開日1999-07-22
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural basis of inhibitor selectivity in MAP kinases.
Structure, 6, 1998
4ERL
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BU of 4erl by Molmil
Crystal structure of the lysine riboswitch bound to a lysine-glycine dipeptide
分子名称: GLYCINE, LYSINE, Lysine riboswitch RNA
著者Garst, A.D, Porter, E, Batey, R.T.
登録日2012-04-20
公開日2012-07-18
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Insights into the regulatory landscape of the lysine riboswitch.
J.Mol.Biol., 423, 2012
4ERM
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BU of 4erm by Molmil
Crystal structure of the dATP inhibited E. coli class Ia ribonucleotide reductase complex at 4 Angstroms resolution
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, 2'-DEOXYADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Zimanyi, C.M, Drennan, C.L.
登録日2012-04-20
公開日2012-07-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (3.95 Å)
主引用文献Tangled up in knots: structures of inactivated forms of E. coli class Ia ribonucleotide reductase.
Structure, 20, 2012
4ERN
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BU of 4ern by Molmil
Crystal structure of the C-terminal domain of human XPB/ERCC-3 excision repair protein at 1.80 A
分子名称: TFIIH basal transcription factor complex helicase XPB subunit
著者Hilario, E, Li, Y, Fan, L.
登録日2012-04-20
公開日2013-01-30
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of the C-terminal half of human XPB helicase and the impact of the disease-causing mutation XP11BE.
Acta Crystallogr.,Sect.D, 69, 2013
4ERO
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BU of 4ero by Molmil
Study on structure and function relationships in human Pirin with Cobalt ion
分子名称: 1,2-ETHANEDIOL, COBALT (II) ION, Pirin
著者Liu, F, Rehmani, I, Fu, R, Esaka, S, Chen, L, Serrano, V, Liu, A.
登録日2012-04-20
公開日2013-05-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Pirin is an iron-dependent redox regulator of NF-kappa B.
Proc.Natl.Acad.Sci.USA, 110, 2013
4ERP
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BU of 4erp by Molmil
Crystal structure of a gemcitabine-diphosphate inhibited E. coli class Ia ribonucleotide reductase complex
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MU-OXO-DIIRON, Ribonucleoside-diphosphate reductase 1 subunit alpha, ...
著者Zimanyi, C.M, Drennan, C.L.
登録日2012-04-20
公開日2012-07-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (4.45 Å)
主引用文献Tangled up in knots: structures of inactivated forms of E. coli class Ia ribonucleotide reductase.
Structure, 20, 2012
4ERQ
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BU of 4erq by Molmil
X-ray structure of WDR5-MLL2 Win motif peptide binary complex
分子名称: Histone-lysine N-methyltransferase MLL2, WD repeat-containing protein 5
著者Dharmarajan, V, Lee, J.-H, Patel, A, Skalnik, D.G, Cosgrove, M.S.
登録日2012-04-20
公開日2012-05-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.906 Å)
主引用文献Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases.
J.Biol.Chem., 287, 2012
4ERR
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BU of 4err by Molmil
1.55 Angstrom Crystal Structure of the Four Helical Bundle Membrane Localization Domain (4HBM) of the Vibrio vulnificus MARTX Effector Domain DUF5
分子名称: Autotransporter adhesin, BROMIDE ION, CHLORIDE ION
著者Minasov, G, Wawrzak, Z, Geissler, B, Shuvalova, L, Dubrovska, I, Winsor, J, Satchell, K.J, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2012-04-20
公開日2012-05-02
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献1.55 Angstrom Crystal Structure of the Four Helical Bundle Membrane Localization Domain (4HBM) of the Vibrio vulnificus MARTX Effector Domain DUF5.
TO BE PUBLISHED
4ERS
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BU of 4ers by Molmil
A Molecular Basis for Negative Regulation of the Glucagon Receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, Fab light chain, ...
著者Murray, J.M, Koth, C.M, Mukund, S.
登録日2012-04-20
公開日2012-08-29
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.637 Å)
主引用文献Molecular basis for negative regulation of the glucagon receptor.
Proc.Natl.Acad.Sci.USA, 109, 2012
4ERT
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BU of 4ert by Molmil
Crystal structure of rabbit ryanodine receptor 1 (2734-2940)
分子名称: GLYCEROL, POTASSIUM ION, Ryanodine receptor 1
著者Yuchi, Z, Lau, K, Van Petegem, F.
登録日2012-04-20
公開日2012-06-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Disease mutations in the ryanodine receptor central region: crystal structures of a phosphorylation hot spot domain.
Structure, 20, 2012
4ERU
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BU of 4eru by Molmil
Crystal Structure of Putative Cytoplasmic Protein, YciF Bacterial Stress Response Protein from Salmonella enterica
分子名称: D-MALATE, MAGNESIUM ION, YciF Bacterial Stress Response Protein
著者Kim, Y, Wu, R, Jedrzejczak, R, Brown, R.N, Cort, J.R, Heffron, F, Nakayasu, E.S, Adkins, J.N, Joachimiak, A, Midwest Center for Structural Genomics (MCSG), Program for the Characterization of Secreted Effector Proteins (PCSEP)
登録日2012-04-20
公開日2012-06-06
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal Structure of Putative Cytoplasmic Protein, YciF Bacterial Stress Response Protein from Salmonella enterica
To be Published
4ERV
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BU of 4erv by Molmil
Crystal structure of human ryanodine receptor 3 (2597-2800)
分子名称: GLYCEROL, Ryanodine receptor 3, SULFATE ION
著者Yuchi, Z, Lau, K, Van Petegem, F.
登録日2012-04-20
公開日2012-06-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Disease mutations in the ryanodine receptor central region: crystal structures of a phosphorylation hot spot domain.
Structure, 20, 2012
4ERW
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BU of 4erw by Molmil
CDK2 in complex with staurosporine
分子名称: 1,2-ETHANEDIOL, Cyclin-dependent kinase 2, STAUROSPORINE
著者Alam, R, Martin, M.P, Zhu, J.-Y, Schonbrunn, E.
登録日2012-04-20
公開日2012-08-22
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A Novel Approach to the Discovery of Small-Molecule Ligands of CDK2.
Chembiochem, 13, 2012
4ERX
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BU of 4erx by Molmil
Crystal structure of the complex of peptidyl-tRNA hydrolase from Pseudomonas aeruginosa with diethylene glycol at 2.5 Angstrom resolution
分子名称: DI(HYDROXYETHYL)ETHER, Peptidyl-tRNA hydrolase
著者Kumar, A, Singh, A, Singh, N, Sinha, M, Sharma, S, Arora, A, Singh, T.P.
登録日2012-04-21
公開日2012-05-09
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of the complex of peptidyl-tRNA hydrolase from Pseudomonas aeruginosa with diethylene glycol at 2.5 Angstrom resolution
To be Published
4ERY
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BU of 4ery by Molmil
X-ray structure of WDR5-MLL3 Win motif peptide binary complex
分子名称: Histone-lysine N-methyltransferase MLL3, WD repeat-containing protein 5
著者Dharmarajan, V, Lee, J.-H, Patel, A, Skalnik, D.G, Cosgrove, M.S.
登録日2012-04-21
公開日2012-05-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases.
J.Biol.Chem., 287, 2012
4ERZ
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BU of 4erz by Molmil
X-ray structure of WDR5-MLL4 Win motif peptide binary complex
分子名称: Histone-lysine N-methyltransferase MLL4, WD repeat-containing protein 5
著者Dharmarajan, V, Lee, J.-H, Patel, A, Skalnik, D.G, Cosgrove, M.S.
登録日2012-04-21
公開日2012-05-30
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases.
J.Biol.Chem., 287, 2012
4ES0
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BU of 4es0 by Molmil
X-ray structure of WDR5-SETd1b Win motif peptide binary complex
分子名称: Histone-lysine N-methyltransferase SETD1B, WD repeat-containing protein 5
著者Dharmarajan, V, Lee, J.-H, Patel, A, Skalnik, D.G, Cosgrove, M.S.
登録日2012-04-21
公開日2012-05-30
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.817 Å)
主引用文献Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases.
J.Biol.Chem., 287, 2012
4ES1
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BU of 4es1 by Molmil
Double-stranded Endonuclease Activity in B. halodurans Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-associated Cas2 Protein
分子名称: BH0342 protein
著者Ke, A, Nam, K.H.
登録日2012-04-21
公開日2012-08-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献Double-stranded endonuclease activity in Bacillus halodurans clustered regularly interspaced short palindromic repeats (CRISPR)-associated Cas2 protein.
J. Biol. Chem., 287, 2012
4ES2
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BU of 4es2 by Molmil
Double-stranded Endonuclease Activity in B. halodurans Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-associated Cas2 Protein
分子名称: BH0342 protein
著者Ke, A, Nam, K.H.
登録日2012-04-21
公開日2012-08-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.299 Å)
主引用文献Double-stranded endonuclease activity in Bacillus halodurans clustered regularly interspaced short palindromic repeats (CRISPR)-associated Cas2 protein.
J. Biol. Chem., 287, 2012
4ES3
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BU of 4es3 by Molmil
Double-stranded Endonuclease Activity in B. halodurans Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)-associated Cas2 Protein
分子名称: 1,2-ETHANEDIOL, BH0342 protein
著者Ke, A, Nam, K.H.
登録日2012-04-21
公開日2012-08-22
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.704 Å)
主引用文献Double-stranded endonuclease activity in Bacillus halodurans clustered regularly interspaced short palindromic repeats (CRISPR)-associated Cas2 protein.
J. Biol. Chem., 287, 2012

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