PDB: 10540 件ウェブページステータス検索Chemie searchBIRD

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2BAM	RESTRICTION ENDONUCLEASE BAMHI COMPLEX WITH DNA AND CALCIUM IONS (PRE-REACTIVE COMPLEX). 分子名称: CALCIUM ION, DNA (5'-D(*TP*AP*TP*GP*GP*AP*TP*CP*CP*AP*TP*A)-3'), PROTEIN (ENDONUCLEASE BAMHI) 著者 Viadiu, H, Aggarwal, A.K. 登録日 1998-08-19 公開日 1999-10-31 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The role of metals in catalysis by the restriction endonuclease BamHI. Nat.Struct.Biol., 5, 1998
1MG0	Horse Liver Alcohol Dehydrogenase Complexed With NAD+ and 2,3-Difluorobenzyl Alcohol 分子名称: 2,3-DIFLUOROBENZYL ALCOHOL, Alcohol Dehydrogenase E chain, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... 著者 Rubach, J.K, Plapp, B.V. 登録日 2002-08-14 公開日 2002-11-13 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Mobility of Fluorobenzyl Alcohols Bound to Liver Alcohol Dehydrogenases as Determined by NMR and X-ray Crystallographic Studies Biochemistry, 41, 2002
1MHY	METHANE MONOOXYGENASE HYDROXYLASE 分子名称: FE (III) ION, METHANE MONOOXYGENASE HYDROXYLASE 著者 Elango, N, Radhakrishnan, R, Froland, W.A, Waller, B.J, Earhart, C.A, Lipscomb, J.D, Ohlendorf, D.H. 登録日 1996-10-21 公開日 1997-05-15 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure of the hydroxylase component of methane monooxygenase from Methylosinus trichosporium OB3b Protein Sci., 6, 1997
1MB0	CRYSTAL STRUCTURE OF THE RESPONSE REGULATOR DIVK AT PH 8.0 IN COMPLEX WITH MN2+ 分子名称: MANGANESE (II) ION, cell division response regulator DivK 著者 Guillet, V, Ohta, N, Cabantous, S, Newton, A, Samama, J.-P, Structural Proteomics in Europe (SPINE) 登録日 2002-08-02 公開日 2002-12-04 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystallographic and Biochemical Studies of DivK Reveal Novel Features of an Essential Response Regulator in Caulobacter crescentus. J.Biol.Chem., 277, 2002
1MIC	GRAMICIDIN A: LEFT-HANDED PARALLEL DOUBLE HELICAL FORM IN METHANOL IN THE PRESENCE OF CACL2, NMR, 20 STRUCTURES 分子名称: GRAMICIDIN A 著者 Chen, Y, Tucker, A, Wallace, B.A. 登録日 1996-05-22 公開日 1997-02-12 最終更新日 2023-11-15 実験手法 SOLUTION NMR 主引用文献 Solution Structure of a Parallel Left-Handed Double-Helical Gramicidin-A Determined by 2D 1H NMR. J.Mol.Biol., 264, 1996
1MMJ	Porcine pancreatic elastase complexed with a potent peptidyl inhibitor, FR136706 分子名称: 2-[4-[[(S)-1-[[(S)-2-[[(RS)-3,3,3-TRIFLUORO-1-ISOPROPYL-2-OXOPROPYL]AMINOCARBONYL]PYRROLIDIN-1-YL-]CARBONYL]-2-METHYLPROPYL]AMINOCARBONYL]BENZOYLAMINO]ACETIC ACID, CALCIUM ION, SULFATE ION, ... 著者 Kinoshita, T. 登録日 2002-09-04 公開日 2002-12-23 最終更新日 2017-10-11 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 True interaction mode of porcine pancreatic elastase with FR136706, a potent peptidyl inhibitor Bioorg.Med.Chem.Lett., 13, 2003
8A5X	Crystal structure of phosphatidyl inositol 4-kinase II beta in complex with MM1373 分子名称: 4-azanyl-7-[3-(hydroxymethyl)phenyl]quinazoline-6-carboxamide, Phosphatidylinositol 4-kinase type 2-beta,Endolysin 著者 Klima, M, Boura, E. 登録日 2022-06-16 公開日 2022-10-05 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structure-based design and modular synthesis of novel PI4K class II inhibitors bearing a 4-aminoquinazoline scaffold. Bioorg.Med.Chem.Lett., 76, 2022
3LZQ	Crystal Structure Analysis of Manganese treated P19 protein from Campylobacter jejuni at 1.41 A at pH 9 分子名称: COPPER (II) ION, MANGANESE (II) ION, P19 protein, ... 著者 Doukov, T.I, Chan, A.C.K, Scofield, M, Ramin, A.B, Tom-Yew, S.A.L, Murphy, M.E.P. 登録日 2010-03-01 公開日 2010-07-21 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.41 Å) 主引用文献 Structure and Function of P19, a High-Affinity Iron Transporter of the Human Pathogen Campylobacter jejuni. J.Mol.Biol., 401, 2010
3LZR	Crystal Structure Analysis of Manganese treated P19 protein from Campylobacter jejuni at 2.73 A at pH 9 and Manganese peak wavelength (1.893 A) 分子名称: COPPER (II) ION, MANGANESE (II) ION, P19 protein, ... 著者 Doukov, T.I, Chan, A.C.K, Scofield, M, Ramin, A.B, Tom-Yew, S.A.L, Murphy, M.E.P. 登録日 2010-03-01 公開日 2010-07-21 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.73 Å) 主引用文献 Structure and Function of P19, a High-Affinity Iron Transporter of the Human Pathogen Campylobacter jejuni. J.Mol.Biol., 401, 2010
2JWZ	Mutations in the hydrophobic core of ubiquitin differentially affect its recognition by receptor proteins 分子名称: Ubiquitin 著者 Haririnia, A, Verma, R, Purohit, N, Twarog, M, Deshaies, R, Bolon, D, Fushman, D. 登録日 2007-10-31 公開日 2008-01-08 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Mutations in the hydrophobic core of ubiquitin differentially affect its recognition by receptor proteins. J.Mol.Biol., 375, 2008
7E4Z	Crystal structure of tubulin in complex with Maytansinol 分子名称: (1R,2S,3S,5S,6S,16E,18E,20R,21S)-11-chloro-6,21-dihydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-4,24-dioxa-9,22-diazatetracyclo[19.3.1.1~10,14~.0~3,5~]hexacosa-10(26),11,13,16,18-pentaene-8,23-dione, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... 著者 Wang, Y, Li, W. 登録日 2021-02-16 公開日 2021-07-07 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.69 Å) 主引用文献 C3 ester side chain plays a pivotal role in the antitumor activity of Maytansinoids. Biochem.Biophys.Res.Commun., 566, 2021
7E4Q	Crystal structure of tubulin in complex with L-DM1-SMe 分子名称: (1S,2R,3R,5R,6R,16E,18E,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.1~10,14~.0~3,5~]hexacosa-10(26),11,13,16,18-pentaen-6-yl (2S)-2-{methyl[3-(methyldisulfanyl)propanoyl]amino}propanoate (non-preferred name), 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... 著者 Wang, Y, Li, W. 登録日 2021-02-14 公開日 2021-07-07 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.501 Å) 主引用文献 C3 ester side chain plays a pivotal role in the antitumor activity of Maytansinoids. Biochem.Biophys.Res.Commun., 566, 2021
7EJU	Junin virus(JUNV) RNA polymerase L complexed with Z protein 分子名称: MAGNESIUM ION, RING finger protein Z, RNA-directed RNA polymerase L, ... 著者 Chen, Y. 登録日 2021-04-02 公開日 2021-07-07 最終更新日 2022-01-19 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Structural basis for recognition and regulation of arenavirus polymerase L by Z protein. Nat Commun, 12, 2021
8FGX	Cryo-EM structure of the STAR-0215 Fab in complex with active human plasma kallikrein 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Plasma kallikrein light chain, STAR-0215 Heavy chain, ... 著者 Fuller, J.R, Biris, N, Bista, P. 登録日 2022-12-13 公開日 2023-09-06 最終更新日 2023-10-25 実験手法 ELECTRON MICROSCOPY (2.62 Å) 主引用文献 STAR-0215 is a Novel, Long-Acting Monoclonal Antibody Inhibitor of Plasma Kallikrein for the Potential Treatment of Hereditary Angioedema. J.Pharmacol.Exp.Ther., 387, 2023
1NG8	G15-Gramicidin A in Sodium Dodecyl Sulfate Micelles (NMR) 分子名称: GRAMICIDIN A 著者 Sham, S.S, Townsley, L.E, Hinton, J.F. 登録日 2002-12-17 公開日 2002-12-31 最終更新日 2023-11-15 実験手法 SOLUTION NMR 主引用文献 The Structure, Cation Binding, Transport and Conductance of Gly15-Gramicidin a Incorporated Into Sds Micelles and Pc/Pg Vesicles Biochemistry, 42, 2003
4X9S	CRYSTAL STRUCTURE OF HISAP FROM STREPTOMYCES SP. MG1 分子名称: Phosphoribosyl isomerase A, SULFATE ION 著者 MICHALSKA, K, VERDUZCO-CASTRO, E.A, ENDRES, M, BARONA-GOMEZ, F, JOACHIMIAK, A, Midwest Center for Structural Genomics (MCSG) 登録日 2014-12-11 公開日 2014-12-24 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Co-occurrence of analogous enzymes determines evolution of a novel ( beta alpha )8-isomerase sub-family after non-conserved mutations in flexible loop. Biochem. J., 473, 2016
6I8H	Structure of the plant immune signaling node EDS1 (enhanced disease susceptibility 1) in complex with nanobody ENB15 分子名称: EDS1-specific nanobody, Protein EDS1L 著者 Niefind, K, Voss, M, Toelzer, C. 登録日 2018-11-20 公開日 2019-10-02 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (3.682 Å) 主引用文献 Arabidopsis immunity regulator EDS1 in a PAD4/SAG101-unbound form is a monomer with an inherently inactive conformation. J.Struct.Biol., 208, 2019
6I8T	THE CATALYTIC FRAGMENT OF POLY(ADP-RIBOSE) POLYMERASE COMPLEXED WITH AN ISOINDOLINONE INHIBITOR 分子名称: (1~{R})-2-(1-cyclohexylpiperidin-4-yl)-1-methyl-3-oxidanylidene-1~{H}-isoindole-4-carboxamide, Poly [ADP-ribose] polymerase 1 著者 Casale, E, Papeo, G, Montagnoli, A. 登録日 2018-11-21 公開日 2019-05-01 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Discovery of Stereospecific PARP-1 Inhibitor Isoindolinone NMS-P515. Acs Med.Chem.Lett., 10, 2019
8FGE	Structure of rat neuronal nitric oxide synthase R349A mutant heme domain in complex with 4-(difluoromethyl)-6-(5-(2-(dimethylamino)ethyl)-2,3-difluorophenethyl)pyridin-2-amine dihydrochloride 分子名称: 4-(difluoromethyl)-6-(2-{5-[2-(dimethylamino)ethyl]-2,3-difluorophenyl}ethyl)pyridin-2-amine, 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, ... 著者 Li, H, Poulos, T.L. 登録日 2022-12-12 公開日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Potent, Selective, and Membrane Permeable 2-Amino-4-Substituted Pyridine-Based Neuronal Nitric Oxide Synthase Inhibitors. J.Med.Chem., 66, 2023
8FGQ	Structure of human endothelial nitric oxide synthase heme domain in complex with 4-(5-(2-(dimethylamino)ethyl)-2,3-difluorophenethyl)-6-methylpyrimidin-2-amine 分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 4-(2-{5-[2-(dimethylamino)ethyl]-2,3-difluorophenyl}ethyl)-6-methylpyrimidin-2-amine, 5,6,7,8-TETRAHYDROBIOPTERIN, ... 著者 Li, H, Poulos, T.L. 登録日 2022-12-12 公開日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Potent, Selective, and Membrane Permeable 2-Amino-4-Substituted Pyridine-Based Neuronal Nitric Oxide Synthase Inhibitors. J.Med.Chem., 66, 2023
6I5A	Tobacco Mosaic Virus 分子名称: Capsid protein 著者 Song, B, Flegler, V, Makbul, C, Rasmussen, T, Bottcher, B. 登録日 2018-11-13 公開日 2019-02-20 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (2.3 Å) 主引用文献 Capabilities of the Falcon III detector for single-particle structure determination. Ultramicroscopy, 203, 2019
8FTP	FphH, Staphylococcus aureus fluorophosphonate-binding serine hydrolases H, apo form 分子名称: Alpha/beta fold hydrolase, CALCIUM ION 著者 Fellner, M. 登録日 2023-01-12 公開日 2023-10-11 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.37 Å) 主引用文献 Biochemical and Cellular Characterization of the Function of Fluorophosphonate-Binding Hydrolase H (FphH) in Staphylococcus aureus Support a Role in Bacterial Stress Response. Acs Infect Dis., 9, 2023
8FG1	Human diaphanous inhibitory domain bound to diaphanous autoregulatory domain 分子名称: Protein diaphanous homolog 1 著者 Ramirez, L.M.S, Theophall, G, Premo, A, Manigrasso, M, Yepuri, G, Burz, D, Ramasamy, R, Schmidt, A.M, Shekhtman, A. 登録日 2022-12-12 公開日 2023-10-25 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Disruption of the productive encounter complex results in dysregulation of DIAPH1 activity. J.Biol.Chem., 299, 2023
8FGN	Structure of human endothelial nitric oxide synthase heme domain in complex with 6-(5-(2-(dimethylamino)ethyl)-2,3-difluorophenethyl)pyridin-2-amine 分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5,6,7,8-TETRAHYDROBIOPTERIN, 6-(2-{5-[2-(dimethylamino)ethyl]-2,3-difluorophenyl}ethyl)pyridin-2-amine, ... 著者 Li, H, Poulos, T.L. 登録日 2022-12-12 公開日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Potent, Selective, and Membrane Permeable 2-Amino-4-Substituted Pyridine-Based Neuronal Nitric Oxide Synthase Inhibitors. J.Med.Chem., 66, 2023
8FGO	Structure of human endothelial nitric oxide synthase heme domain in complex with 6-(5-(2-(dimethylamino)ethyl)-2,3-difluorophenethyl)-4-methylpyridin-2-amine 分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5,6,7,8-TETRAHYDROBIOPTERIN, 6-(2-{5-[2-(dimethylamino)ethyl]-2,3-difluorophenyl}ethyl)-4-methylpyridin-2-amine, ... 著者 Li, H, Poulos, T.L. 登録日 2022-12-12 公開日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.799 Å) 主引用文献 Potent, Selective, and Membrane Permeable 2-Amino-4-Substituted Pyridine-Based Neuronal Nitric Oxide Synthase Inhibitors. J.Med.Chem., 66, 2023

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