PDB: 35463 件ウェブページステータス検索Chemie searchBIRD

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2PG1	Structural analysis of a cytoplasmic dynein Light Chain-Intermediate Chain complex 分子名称: Cytoplasmic dynein 1 intermediate chain 2, Dynein light chain 1, cytoplasmic, ... 著者 Williams, J.C, Hendrickson, W.A. 登録日 2007-04-06 公開日 2007-06-05 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural and thermodynamic characterization of a cytoplasmic dynein light chain-intermediate chain complex Proc.Natl.Acad.Sci.Usa, 104, 2007
8C18	Solution structure of carotenoid-binding protein AstaPo1 in complex with astaxanthin 分子名称: ASTAXANTHIN, Astaxanthin binding fasciclin family protein 著者 Kornilov, F.D, Savitskaya, A.G, Slonimskiy, Y.B, Goncharuk, S.A, Sluchanko, N.N, Mineev, K.S. 登録日 2022-12-20 公開日 2023-04-05 最終更新日 2024-06-19 実験手法 SOLUTION NMR 主引用文献 Structural basis for the ligand promiscuity of the neofunctionalized, carotenoid-binding fasciclin domain protein AstaP. Commun Biol, 6, 2023
4UVS	Crystal structure of human tankyrase 2 in complex with 5-amino-3- pentyl-1,2-dihydroisoquinolin-1-one 分子名称: 5-amino-3-pentylisoquinolin-1(2H)-one, SULFATE ION, TANKYRASE-2, ... 著者 Narwal, M, Haikarainen, T, Lehtio, L. 登録日 2014-08-08 公開日 2015-07-29 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Exploration of the Nicotinamide-Binding Site of the Tankyrases, Identifying 3-Arylisoquinolin-1-Ones as Potent and Selective Inhibitors in Vitro. Bioorg.Med.Chem., 23, 2015
6VQ7	Mammalian V-ATPase from rat brain - composite model of rotational state 2 bound to ADP and SidK (built from focused refinement models) 分子名称: ADENOSINE-5'-DIPHOSPHATE, ATPase H+-transporting V1 subunit A, ATPase H+-transporting V1 subunit D, ... 著者 Abbas, Y.M, Rubinstein, J.L. 登録日 2020-02-04 公開日 2020-03-18 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Structure of V-ATPase from the mammalian brain. Science, 367, 2020
8C0C	X-ray crystal structure of PPAR gamma ligand binding domain in complex with CZ46 分子名称: (2~{R})-2-[4-(naphthalen-1-ylmethoxy)phenyl]-4-oxidanyl-3-phenyl-2~{H}-furan-5-one, Peroxisome proliferator-activated receptor gamma 著者 Capelli, D, Montanari, R, Pochetti, G, Villa, S, Meneghetti, F. 登録日 2022-12-16 公開日 2023-04-26 最終更新日 2024-06-19 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Biological Screening and Crystallographic Studies of Hydroxy gamma-Lactone Derivatives to Investigate PPAR gamma Phosphorylation Inhibition. Biomolecules, 13, 2023
4UX4	Crystal structure of human tankyrase 2 in complex with 1-methyl-7-(4- methylphenyl)-5-oxo-5,6-dihydro-1,6-naphthyridin-1-ium 分子名称: (1S)-1-methyl-7-(4-methylphenyl)-5-oxo-1,5-dihydro-1,6-naphthyridin-1-ium, GLYCEROL, SULFATE ION, ... 著者 Haikarainen, T, Lehtio, L. 登録日 2014-08-19 公開日 2015-06-10 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure-Based Design, Synthesis and Evaluation in Vitro of Arylnaphthyridinones, Arylpyridopyrimidinones and Their Tetrahydro Derivatives as Inhibitors of the Tankyrases. Bioorg.Med.Chem., 23, 2015
6VJJ	Crystal Structure of wild-type KRAS4b (GMPPNP-bound) in complex with RAS-binding domain (RBD) of RAF1/CRAF 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, CHLORIDE ION, ... 著者 Tran, T.H, Dharmaiah, S, Simanshu, D.K. 登録日 2020-01-16 公開日 2020-11-25 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 KRAS interaction with RAF1 RAS-binding domain and cysteine-rich domain provides insights into RAS-mediated RAF activation. Nat Commun, 12, 2021
4V29	The crystal structure of Arabidopsis thaliana CAR4 in complex with two calcium ions 分子名称: AT3G17980, CALCIUM ION 著者 Diaz, M, Albert, A. 登録日 2014-10-07 公開日 2014-12-17 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 C2-Domain Abscisic Acid-Related Proteins Mediate the Interaction of Pyr/Pyl/Rcar Abscisic Acid Receptors with the Plasma Membrane and Regulate Abscisic Acid Sensitivity in Arabidopsis. Plant Cell, 26, 2014
2F4K	Chicken villin subdomain HP-35, K65(NLE), N68H, K70(NLE), PH9 分子名称: Villin-1 著者 Chiu, T.K, Davies, D.R, Kubelka, J, Hofrichter, J, Eaton, W.A. 登録日 2005-11-23 公開日 2006-04-11 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.05 Å) 主引用文献 Sub-microsecond Protein Folding. J.Mol.Biol., 359, 2006
6VQH	Mammalian V-ATPase from rat brain membrane-embedded Vo region rotational state 3 (from focused refinement) 分子名称: ATPase H+-transporting V1 subunit D, ATPase, H+ transporting, ... 著者 Abbas, Y.M, Rubinstein, J.L. 登録日 2020-02-05 公開日 2020-03-18 最終更新日 2024-03-06 実験手法 ELECTRON MICROSCOPY (4.4 Å) 主引用文献 Structure of V-ATPase from the mammalian brain. Science, 367, 2020
1M46	CRYSTAL STRUCTURE OF MLC1P BOUND TO IQ4 OF MYO2P, A CLASS V MYOSIN 分子名称: IQ4 Motif from MYO2P, A Class V Myosin, Myosin light chain 著者 Terrak, M, Dominguez, R. 登録日 2002-07-02 公開日 2002-11-27 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.103 Å) 主引用文献 Two distinct myosin light chain structures are induced by specific variations within the bound IQ motifs-functional implications Embo J., 22, 2003
6VVF	Scabin (Y129H) toxin from Streptomyces scabies 分子名称: Scabin 著者 Heney, K, Lyons, B, Merrill, A.R. 登録日 2020-02-17 公開日 2021-01-20 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Mapping the DNA-Binding Motif of Scabin Toxin, a Guanine Modifying Enzyme from Streptomyces scabies . Toxins, 13, 2021
8CH6	Structure of a late-stage activated spliceosome (BAqr) arrested with a dominant-negative Aquarius mutant (state B complex). 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... 著者 Cretu, C, Schmitzova, J, Pena, V. 登録日 2023-02-07 公開日 2023-05-10 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (5.9 Å) 主引用文献 Structural basis of catalytic activation in human splicing. Nature, 617, 2023
6W13	Human 8-oxoguanine glycosylase interrogating fully intrahelical oxoG lesion DNA 分子名称: 2-(2-ethoxyethoxy)ethanethiol, ACETATE ION, DNA (5'-D(P*AP*CP*CP*TP*GP*G)-3'), ... 著者 Shigdel, U, Verdine, G. 登録日 2020-03-03 公開日 2020-09-23 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.38 Å) 主引用文献 The trajectory of intrahelical lesion recognition and extrusion by the human 8-oxoguanine DNA glycosylase. Nat Commun, 11, 2020
2HBP	Solution Structure of Sla1 Homology Domain 1 分子名称: Cytoskeleton assembly control protein SLA1 著者 Overduin, M, Mahadev, R.K. 登録日 2006-06-14 公開日 2007-04-10 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Structure of Sla1p homology domain 1 and interaction with the NPFxD endocytic internalization motif. Embo J., 26, 2007
4V8U	Crystal Structure of 70S Ribosome with Both Cognate tRNAs in the E and P Sites Representing an Authentic Elongation Complex. 分子名称: 16S RIBOSOMAL RNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... 著者 Gao, Y.G, Feng, S, Chen, Y. 登録日 2012-08-28 公開日 2014-07-09 最終更新日 2019-10-30 実験手法 X-RAY DIFFRACTION (3.7 Å) 主引用文献 Crystal structure of 70S ribosome with both cognate tRNAs in the E and P sites representing an authentic elongation complex. PLoS ONE, 8, 2013
4W4K	Crystal structure of a PE25-PPE41 heterodimer from a type VII secretion system of M. tuberculosis 分子名称: PE family protein PE25, PPE family protein PPE41 著者 Ekiert, D.C, Cox, J.S. 登録日 2014-08-14 公開日 2014-10-01 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structure of a PE-PPE-EspG complex from Mycobacterium tuberculosis reveals molecular specificity of ESX protein secretion. Proc.Natl.Acad.Sci.USA, 111, 2014
8CJ3	Urea-based foldamer inhibitor c3u_7 chimera in complex with ASF1 histone chaperone 分子名称: Histone chaperone ASF1A, c3u_7 chimera inhibitor of histone chaperone ASF1 著者 Perrin, M.E, Li, B, Mbianda, J, Ropars, V, Legrand, P, Douat, C, Ochsenbein, F, Guichard, G. 登録日 2023-02-11 公開日 2023-07-05 最終更新日 2024-07-10 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Unexpected binding modes of inhibitors to the histone chaperone ASF1 revealed by a foldamer scanning approach. Chem.Commun.(Camb.), 59, 2023
8CJ2	Urea-based foldamer inhibitor c3u_5 chimera in complex with ASF1 histone chaperone 分子名称: GLYCEROL, Histone chaperone ASF1A, SULFATE ION, ... 著者 Perrin, M.E, Li, B, Mbianda, J, Ropars, V, Legrand, P, Douat, C, Ochsenbein, F, Guichard, G. 登録日 2023-02-11 公開日 2023-07-05 最終更新日 2024-07-10 実験手法 X-RAY DIFFRACTION (2.127 Å) 主引用文献 Unexpected binding modes of inhibitors to the histone chaperone ASF1 revealed by a foldamer scanning approach. Chem.Commun.(Camb.), 59, 2023
8CJ1	Urea-based foldamer inhibitor c3u_3 chimera in complex with ASF1 histone chaperone 分子名称: Histone chaperone ASF1A, c3u_3 chimera inhibitor of histone chaperone ASF1 著者 Perrin, M.E, Li, B, Mbianda, J, Ropars, V, Legrand, P, Douat, C, Ochsenbein, F, Guichard, G. 登録日 2023-02-11 公開日 2023-07-05 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.564 Å) 主引用文献 Unexpected binding modes of inhibitors to the histone chaperone ASF1 revealed by a foldamer scanning approach. Chem.Commun.(Camb.), 59, 2023
4W6E	Human Tankyrase 1 with small molecule inhibitor 分子名称: 2-(4-{6-[(3S)-3,4-dimethylpiperazin-1-yl]-4-methylpyridin-3-yl}phenyl)-8-(hydroxymethyl)quinazolin-4(3H)-one, Tankyrase-1, ZINC ION 著者 Kazmirski, S.L, Johannes, J, Boriack-Sjodin, P.A, Howard, T. 登録日 2014-08-20 公開日 2015-05-13 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Pyrimidinone nicotinamide mimetics as selective tankyrase and wnt pathway inhibitors suitable for in vivo pharmacology. Acs Med.Chem.Lett., 6, 2015
4UVW	Crystal structure of human tankyrase 2 in complex with 4,5-dimethyl-3- phenyl-1,2-dihydroisoquinolin-1-one 分子名称: 4,5-dimethyl-3-phenylisoquinolin-1(2H)-one, SULFATE ION, TANKYRASE-2, ... 著者 Haikarainen, T, Narwal, M, Lehtio, L. 登録日 2014-08-08 公開日 2015-07-29 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Exploration of the Nicotinamide-Binding Site of the Tankyrases, Identifying 3-Arylisoquinolin-1-Ones as Potent and Selective Inhibitors in Vitro. Bioorg.Med.Chem., 23, 2015
6W0M	Human 8-oxoguanine glycosylase crosslinked with oxoG lesion containing DNA 分子名称: 2-(2-ethoxyethoxy)ethanethiol, DNA (5'-D(P*CP*GP*TP*CP*CP*AP*(8OG)P*GP*TP*CP*TP*AP*C)-3'), DNA (5'-D(P*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*GP*C)-3'), ... 著者 Shigdel, U, Verdine, G. 登録日 2020-03-02 公開日 2020-09-23 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.37 Å) 主引用文献 The trajectory of intrahelical lesion recognition and extrusion by the human 8-oxoguanine DNA glycosylase. Nat Commun, 11, 2020
6W0R	Human 8-oxoguanine glycosylase interrogating fully intrahelical undamaged DNA 分子名称: 2-(2-ethoxyethoxy)ethanethiol, DNA (5'-D(P*CP*AP*GP*GP*TP*C)-3'), DNA (5'-D(P*CP*CP*TP*GP*G)-3'), ... 著者 Shigdel, U, Verdine, G. 登録日 2020-03-02 公開日 2020-09-23 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 The trajectory of intrahelical lesion recognition and extrusion by the human 8-oxoguanine DNA glycosylase. Nat Commun, 11, 2020
4UVY	Crystal structure of human tankyrase 2 in complex with 3-(4- chlorophenyl)-5-methoxy-1,2- dihydroisoquinolin-1-one 分子名称: 3-(4-chlorophenyl)-5-methoxyisoquinolin-1(2H)-one, GLYCEROL, SULFATE ION, ... 著者 Haikarainen, T, Narwal, M, Lehtio, L. 登録日 2014-08-08 公開日 2015-07-29 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Exploration of the Nicotinamide-Binding Site of the Tankyrases, Identifying 3-Arylisoquinolin-1-Ones as Potent and Selective Inhibitors in Vitro. Bioorg.Med.Chem., 23, 2015

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