PDB: 19228 件ウェブページステータス検索Chemie searchBIRD

---

6FUF	Crystal structure of the rhodopsin-mini-Go complex 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Guanine nucleotide-binding protein G(o) subunit alpha, RETINAL, ... 著者 Tsai, C.-J, Weinert, T, Muehle, J, Pamula, F, Nehme, R, Flock, T, Nogly, P, Edwards, P.C, Carpenter, B, Gruhl, T, Ma, P, Deupi, X, Standfuss, J, Tate, C.G, Schertler, G.F.X. 登録日 2018-02-27 公開日 2018-10-03 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.117 Å) 主引用文献 Crystal structure of rhodopsin in complex with a mini-Gosheds light on the principles of G protein selectivity. Sci Adv, 4, 2018
2RN2	STRUCTURAL DETAILS OF RIBONUCLEASE H FROM ESCHERICHIA COLI AS REFINED TO AN ATOMIC RESOLUTION 分子名称: RIBONUCLEASE H 著者 Katayanagi, K, Miyagawa, M, Matsushima, M, Ishikawa, M, Kanaya, S, Nakamura, H, Ikehara, M, Matsuzaki, T, Morikawa, K. 登録日 1992-04-15 公開日 1993-10-31 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.48 Å) 主引用文献 Structural details of ribonuclease H from Escherichia coli as refined to an atomic resolution. J.Mol.Biol., 223, 1992
5KO2	Mouse pgp 34 linker deleted mutant Hg derivative 分子名称: MERCURY (II) ION, Multidrug resistance protein 1A 著者 Xia, D, Esser, L, Zhou, F. 登録日 2016-06-29 公開日 2016-11-30 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Structures of the Multidrug Transporter P-glycoprotein Reveal Asymmetric ATP Binding and the Mechanism of Polyspecificity. J. Biol. Chem., 292, 2017
5KK0	Synechocystis ACO mutant - T136A 分子名称: Apocarotenoid-15,15'-oxygenase, CHLORIDE ION, FE (II) ION 著者 Sui, X, Kiser, P.D, Palczewski, K. 登録日 2016-06-20 公開日 2016-07-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Utilization of Dioxygen by Carotenoid Cleavage Oxygenases. J.Biol.Chem., 290, 2015
6GAP	Crystal structure of the T3D reovirus sigma1 coiled coil tail and body 分子名称: Outer capsid protein sigma-1 著者 Dietrich, M.H, Stehle, T. 登録日 2018-04-11 公開日 2018-04-25 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structural and Functional Features of the Reovirus sigma 1 Tail. J. Virol., 92, 2018
5KOY	Mouse pgp 34 linker deleted bound with ATP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, Multidrug resistance protein 1A 著者 Xia, D, Esser, L, Zhou, F. 登録日 2016-07-01 公開日 2016-12-14 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.85 Å) 主引用文献 Structures of the Multidrug Transporter P-glycoprotein Reveal Asymmetric ATP Binding and the Mechanism of Polyspecificity. J. Biol. Chem., 292, 2017
6GDQ	Fragment-based discovery of a highly potent, orally bioavailable inhibitor which modulates the phosphorylation and catalytic activity of ERK1/2 分子名称: 4-[5-chloranyl-2-(propan-2-ylamino)pyridin-4-yl]-~{N}-[(1~{S})-1-(3-chlorophenyl)-2-oxidanyl-ethyl]-1~{H}-pyrrole-2-carboxamide, DIMETHYL SULFOXIDE, Mitogen-activated protein kinase 1, ... 著者 O'Reilly, M. 登録日 2018-04-24 公開日 2018-05-30 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Fragment-Based Discovery of a Potent, Orally Bioavailable Inhibitor That Modulates the Phosphorylation and Catalytic Activity of ERK1/2. J. Med. Chem., 61, 2018
5KPX	Structure of RelA bound to ribosome in presence of A/R tRNA (Structure IV) 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Loveland, A.B, Bah, E, Madireddy, R, Zhang, Y, Brilot, A.F, Grigorieff, N, Korostelev, A.A. 登録日 2016-07-05 公開日 2016-09-28 最終更新日 2024-10-23 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Ribosome•RelA structures reveal the mechanism of stringent response activation. Elife, 5, 2016
6I82	Crystal structure of partially phosphorylated RET V804M tyrosine kinase domain complexed with PDD00018412 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, FORMIC ACID, ... 著者 Burschowsky, D, Seewooruthun, C, Bayliss, R, Carr, M.D, Echalier, A, Jordan, A.M. 登録日 2018-11-19 公開日 2020-03-11 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Discovery and Optimization of wt-RET/KDR-Selective Inhibitors of RETV804MKinase. Acs Med.Chem.Lett., 11, 2020
5UYK	70S ribosome bound with cognate ternary complex not base-paired to A site codon (Structure I) 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Loveland, A.B, Demo, G, Grigorieff, N, Korostelev, A.A. 登録日 2017-02-24 公開日 2017-06-07 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Ensemble cryo-EM elucidates the mechanism of translation fidelity Nature, 546, 2017
5KPD	Mouse pgp 34 linker deleted double EQ mutant 分子名称: Multidrug resistance protein 1A 著者 Xia, D, Esser, L, Zhou, F. 登録日 2016-07-03 公開日 2016-11-30 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.35 Å) 主引用文献 Structures of the Multidrug Transporter P-glycoprotein Reveal Asymmetric ATP Binding and the Mechanism of Polyspecificity. J. Biol. Chem., 292, 2017
6G9D	Fragment-based discovery of a highly potent, orally bioavailable inhibitor which modulates the phosphorylation and catalytic activity of ERK1/2 分子名称: Mitogen-activated protein kinase 1, SULFATE ION, ~{N}-~{tert}-butyl-2-[5-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxidanylidene-1~{H}-isoindol-2-yl]ethanamide 著者 O'Reilly, M. 登録日 2018-04-10 公開日 2018-05-30 最終更新日 2018-06-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Fragment-Based Discovery of a Potent, Orally Bioavailable Inhibitor That Modulates the Phosphorylation and Catalytic Activity of ERK1/2. J. Med. Chem., 61, 2018
5VC7	VCP like ATPase from T. acidophilum (VAT) - conformation 1 分子名称: ADENOSINE-5'-TRIPHOSPHATE, VCP-like ATPase 著者 Ripstein, Z.A, Huang, R, Augustyniak, R, Kay, L.E, Rubinstein, J.L. 登録日 2017-03-31 公開日 2017-04-26 最終更新日 2020-01-15 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Structure of a AAA+ unfoldase in the process of unfolding substrate. Elife, 6, 2017
6FOA	Human Xylosyltransferase 1 apo structure 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHATE ION, SODIUM ION, ... 著者 Briggs, D.C, Hohenester, E. 登録日 2018-02-06 公開日 2018-05-02 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.869 Å) 主引用文献 Structural Basis for the Initiation of Glycosaminoglycan Biosynthesis by Human Xylosyltransferase 1. Structure, 26, 2018
5KQZ	Protease E35D-CaP2 分子名称: N-[(2R)-2-({N~5~-[amino(iminio)methyl]-L-ornithyl-L-valyl}amino)-4-methylpentyl]-L-phenylalanyl-L-alpha-glutamyl-L-alanyl-L-norleucinamide, Protease 著者 Liu, Z, Poole, K.M, Mahon, B.P, McKenna, R, Fanucci, G.E. 登録日 2016-07-06 公開日 2016-09-21 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Effects of Hinge-region Natural Polymorphisms on Human Immunodeficiency Virus-Type 1 Protease Structure, Dynamics, and Drug Pressure Evolution. J.Biol.Chem., 291, 2016
6G9M	Fragment-based discovery of a highly potent, orally bioavailable inhibitor which modulates the phosphorylation and catalytic activity of ERK1/2 分子名称: 2-[5-[5-chloranyl-2-(oxan-4-ylamino)pyrimidin-4-yl]-3-oxidanylidene-1~{H}-isoindol-2-yl]-~{N}-(2-phenylpropan-2-yl)ethanamide, Mitogen-activated protein kinase 1, SULFATE ION 著者 O'Reilly, M. 登録日 2018-04-11 公開日 2018-05-30 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Fragment-Based Discovery of a Potent, Orally Bioavailable Inhibitor That Modulates the Phosphorylation and Catalytic Activity of ERK1/2. J. Med. Chem., 61, 2018
6IIL	USP14 catalytic domain bind to IU1-47 分子名称: 1-[1-(4-chlorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(piperidin-1-yl)ethan-1-one, Ubiquitin carboxyl-terminal hydrolase 14 著者 Mei, Z.Q, Wang, Y.W, Wang, F, Wang, J.W, He, W, Ding, S, Li, J.W. 登録日 2018-10-07 公開日 2018-12-12 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Small molecule inhibitors reveal allosteric regulation of USP14 via steric blockade. Cell Res., 28, 2018
6GAK	Crystal structure of the T1L reovirus sigma1 coiled coil tail (chloride) 分子名称: CHLORIDE ION, Outer capsid protein sigma-1 著者 Dietrich, M.H, Stehle, T. 登録日 2018-04-11 公開日 2018-04-25 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.43 Å) 主引用文献 Structural and Functional Features of the Reovirus sigma 1 Tail. J. Virol., 92, 2018
6VI8	Observing a ring-cleaving dioxygenase in action through a crystalline lens - a superoxo bound structure 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-HYDROXYANTHRANILIC ACID, 3-hydroxyanthranilate 3,4-dioxygenase, ... 著者 Wang, Y, Liu, F, Yang, Y, Liu, A. 登録日 2020-01-12 公開日 2020-07-29 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Observing 3-hydroxyanthranilate-3,4-dioxygenase in action through a crystalline lens. Proc.Natl.Acad.Sci.USA, 117, 2020
5V9X	Structure of Mycobacterium smegmatis helicase Lhr bound to ssDNA and AMP-PNP 分子名称: ATP-dependent DNA helicase, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Ordonez, H, Jacewicz, A, Ferrao, R, Shuman, S. 登録日 2017-03-23 公開日 2017-12-06 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.797 Å) 主引用文献 Structure of mycobacterial 3'-to-5' RNA:DNA helicase Lhr bound to a ssDNA tracking strand highlights distinctive features of a novel family of bacterial helicases. Nucleic Acids Res., 46, 2018
6VIA	Observing a ring-cleaving dioxygenase in action through a crystalline lens - a seven-membered lactone bound structure 分子名称: (2R,3E)-2-hydroxy-3-imino-2,3-dihydrooxepine-4-carboxylic acid, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-hydroxyanthranilate 3,4-dioxygenase, ... 著者 Wang, Y, Liu, F, Yang, Y, Liu, A. 登録日 2020-01-12 公開日 2020-07-29 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.591 Å) 主引用文献 Observing 3-hydroxyanthranilate-3,4-dioxygenase in action through a crystalline lens. Proc.Natl.Acad.Sci.USA, 117, 2020
6GDM	Fragment-based discovery of a highly potent, orally bioavailable inhibitor which modulates the phosphorylation and catalytic activity of ERK1/2 分子名称: (3~{R})-1-[2-oxidanylidene-2-[4-(4-pyrimidin-2-ylphenyl)piperazin-1-yl]ethyl]-~{N}-(3-pyridin-4-yl-1~{H}-indazol-5-yl)pyrrolidine-3-carboxamide, DIMETHYL SULFOXIDE, Mitogen-activated protein kinase 1, ... 著者 O'Reilly, M. 登録日 2018-04-24 公開日 2018-05-30 最終更新日 2018-06-27 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Fragment-Based Discovery of a Potent, Orally Bioavailable Inhibitor That Modulates the Phosphorylation and Catalytic Activity of ERK1/2. J. Med. Chem., 61, 2018
8C01	Enp1TAP_A population of yeast small ribosomal subunit precursors 分子名称: 18S rRNA precursor, 20S-pre-rRNA D-site endonuclease NOB1, 40S ribosomal protein S0-A, ... 著者 Milkereit, P, Poell, G. 登録日 2022-12-15 公開日 2022-12-28 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Impact of the yeast S0/uS2-cluster ribosomal protein rpS21/eS21 on rRNA folding and the architecture of small ribosomal subunit precursors. Plos One, 18, 2023
8C00	Enp1TAP-S21_A population of yeast small ribosomal subunit precursors depleted of rpS21/eS21 分子名称: 18S rRNA precursor, 40S ribosomal protein S1-A, 40S ribosomal protein S11-A, ... 著者 Milkereit, P, Poell, G. 登録日 2022-12-15 公開日 2022-12-28 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Impact of the yeast S0/uS2-cluster ribosomal protein rpS21/eS21 on rRNA folding and the architecture of small ribosomal subunit precursors. Plos One, 18, 2023
6FSZ	Structure of the nuclear RNA exosome 分子名称: ATP-dependent RNA helicase DOB1, Exosome complex component CSL4, Exosome complex component MTR3, ... 著者 Schuller, J.M, Falk, S, Conti, E. 登録日 2018-02-20 公開日 2018-03-21 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (4.6 Å) 主引用文献 Structure of the nuclear exosome captured on a maturing preribosome. Science, 360, 2018

<353354355356357358359360361362363364365366367368>