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3E68
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Structure of murine INOS oxygenase domain with inhibitor AR-C130232
分子名称: 1,2-ETHANEDIOL, 5,6,7,8-TETRAHYDROBIOPTERIN, N-[2-(6-AMINO-4-METHYLPYRIDIN-2-YL)ETHYL]-4-CYANOBENZAMIDE, ...
著者Garcin, E.D, Arvai, A.S, Rosenfeld, R.J, Kroeger, M.D, Crane, B.R, Andersson, G, Andrews, G, Hamley, P.J, Mallinder, P.R, Nicholls, D.J, St-Gallay, S.A, Tinker, A.C, Gensmantel, N.P, Mete, A, Cheshire, D.R, Connolly, S, Stueh, D.J, Aberg, A, Wallace, A.V, Tainer, J.A, Getzoff, E.D.
登録日2008-08-14
公開日2008-10-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase.
Nat.Chem.Biol., 4, 2008
3E7M
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Structure of murine iNOS oxygenase domain with inhibitor AR-C95791
分子名称: 1,2-ETHANEDIOL, 5,6,7,8-TETRAHYDROBIOPTERIN, ETHYL 4-[(4-METHYLPYRIDIN-2-YL)AMINO]PIPERIDINE-1-CARBOXYLATE, ...
著者Garcin, E.D, Arvai, A.S, Rosenfeld, R.J, Kroeger, M.D, Crane, B.R, Andersson, G, Andrews, G, Hamley, P.J, Mallinder, P.R, Nicholls, D.J, St-Gallay, S.A, Tinker, A.C, Gensmantel, N.P, Mete, A, Cheshire, D.R, Connolly, S, Stuehr, D.J, Aberg, A, Wallace, A.V, Tainer, J.A, Getzoff, E.D.
登録日2008-08-18
公開日2008-10-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase.
Nat.Chem.Biol., 4, 2008
1TER
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BU of 1ter by Molmil
SOLUTION STRUCTURE OF TERTIAPIN DETERMINED USING NUCLEAR MAGNETIC RESONANCE AND DISTANCE GEOMETRY
分子名称: TERTIAPIN
著者Xu, X, Nelson, J.W.
登録日1994-04-08
公開日1995-02-07
最終更新日2017-11-29
実験手法SOLUTION NMR
主引用文献Solution structure of tertiapin determined using nuclear magnetic resonance and distance geometry.
Proteins, 17, 1993
3E7S
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Structure of bovine eNOS oxygenase domain with inhibitor AR-C95791
分子名称: ETHYL 4-[(4-METHYLPYRIDIN-2-YL)AMINO]PIPERIDINE-1-CARBOXYLATE, HEME C, Nitric oxide synthase, ...
著者Garcin, E.D, Arvai, A.S, Rosenfeld, R.J, Kroeger, M.D, Crane, B.R, Andersson, G, Andrews, G, Hamley, P.J, Mallinder, P.R, Nicholls, D.J, St-Gallay, S.A, Tinker, A.C, Gensmantel, N.P, Mete, A, Cheshire, D.R, Connolly, S, Stuehr, D.J, Aberg, A, Wallace, A.V, Tainer, J.A, Getzoff, E.D.
登録日2008-08-18
公開日2008-10-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase.
Nat.Chem.Biol., 4, 2008
3EDV
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BU of 3edv by Molmil
Crystal Structure of Repeats 14-16 of Beta2-Spectrin
分子名称: MAGNESIUM ION, Spectrin beta chain, brain 1
著者Michaely, P, Tomchick, D.R.
登録日2008-09-03
公開日2009-01-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.951 Å)
主引用文献Localization and Structure of the Ankyrin-binding Site on beta2-Spectrin
J.Biol.Chem., 284, 2009
3EJ8
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Structure of double mutant of human iNOS oxygenase domain with bound immidazole
分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, HEME C, IMIDAZOLE, ...
著者Garcin, E.D, Arvai, A.S, Rosenfeld, R.J, Kroeger, M.D, Crane, B.R, Andersson, G, Andrews, G, Hamley, P.J, Mallinder, P.R, Nicholls, D.J, St-Gallay, S.A, Tinker, A.C, Gensmantel, N.P, Mete, A, Cheshire, D.R, Connolly, S, Stuehr, D.J, Aberg, A, Wallace, A.V, Tainer, J.A, Getzoff, E.D.
登録日2008-09-17
公開日2008-10-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase.
Nat.Chem.Biol., 4, 2008
3E3R
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BU of 3e3r by Molmil
Crystal structure and biochemical characterization of recombinant human calcyphosine delineates a novel EF-hand-containing protein family
分子名称: CALCIUM ION, Calcyphosin
著者Dong, H.
登録日2008-08-07
公開日2008-08-26
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Crystal-structure and biochemical characterization of recombinant human calcyphosine delineates a novel EF-hand-containing protein family
J.Mol.Biol., 383, 2008
3EAH
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BU of 3eah by Molmil
Structure of inhibited human eNOS oxygenase domain
分子名称: (3S,5E)-3-propyl-3,4-dihydrothieno[2,3-f][1,4]oxazepin-5(2H)-imine, (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, ...
著者Garcin, E.D, Arvai, A.S, Rosenfeld, R.J, Kroeger, M.D, Crane, B.R, Andersson, G, Andrews, G, Hamley, P.J, Mallinder, P.R, Nicholls, D.J, St-Gallay, S.A, Tinker, A.C, Gensmantel, N.P, Mete, A, Cheshire, D.R, Connolly, S, Stuehr, D.J, Aberg, A, Wallace, A.V, Tainer, J.A, Getzoff, E.D.
登録日2008-08-25
公開日2008-10-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase.
Nat.Chem.Biol., 4, 2008
3E6O
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Structure of murine INOS oxygenase domain with inhibitor AR-C124355
分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, N-[2-(4-AMINO-5,8-DIFLUORO-1,2-DIHYDROQUINAZOLIN-2-YL)ETHYL]-3-FURAMIDE, Nitric oxide synthase, ...
著者Garcin, E.D, Arvai, A.S, Rosenfeld, R.J, Kroeger, M.D, Crane, B.R, Andersson, G, Andrews, G, Hamley, P.J, Mallinder, P.R, Nicholls, D.J, St-Gallay, S.A, Tinker, A.C, Gensmantel, N.P, Mete, A, Cheshire, D.R, Connolly, S, Stueh, D.J, Aberg, A, Wallace, A.V, Tainer, J.A, Getzoff, E.D.
登録日2008-08-15
公開日2008-10-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase.
Nat.Chem.Biol., 4, 2008
3E7G
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BU of 3e7g by Molmil
Structure of human INOSOX with inhibitor AR-C95791
分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, ETHYL 4-[(4-METHYLPYRIDIN-2-YL)AMINO]PIPERIDINE-1-CARBOXYLATE, Nitric oxide synthase, ...
著者Garcin, E.D, Arvai, A.S, Rosenfeld, R.J, Kroeger, M.D, Crane, B.R, Andersson, G, Andrews, G, Hamley, P.J, Mallinder, P.R, Nicholls, D.J, St-Gallay, S.A, Tinker, A.C, Gensmantel, N.P, Mete, A, Cheshire, D.R, Connolly, S, Stueh, D.J, Aberg, A, Wallace, A.V, Tainer, J.A, Getzoff, E.D.
登録日2008-08-18
公開日2008-10-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase.
Nat.Chem.Biol., 4, 2008
6X34
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BU of 6x34 by Molmil
Pig R615C RyR1 EGTA (all classes, open)
分子名称: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine Receptor, ZINC ION
著者Woll, K.W, Haji-Ghassemi, O, Van Petegem, F.
登録日2020-05-21
公開日2021-01-13
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Pathological conformations of disease mutant Ryanodine Receptors revealed by cryo-EM.
Nat Commun, 12, 2021
1HD3
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BU of 1hd3 by Molmil
A-SPECTRIN SH3 DOMAIN F52Y MUTANT
分子名称: GLYCEROL, SPECTRIN ALPHA CHAIN, SULFATE ION
著者Vega, M.C, Viguera, A.R, Serrano, L.
登録日2000-11-06
公開日2001-11-01
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Unspecific Hydrophobic Stabilization of Folding Transition States
Proc.Natl.Acad.Sci.USA, 99, 2002
1W2F
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BU of 1w2f by Molmil
Human Inositol (1,4,5)-trisphosphate 3-kinase substituted with selenomethionine
分子名称: INOSITOL-TRISPHOSPHATE 3-KINASE A, SULFATE ION
著者Gonzalez, B, Schell, M.J, Irvine, R.F, Williams, R.L.
登録日2004-07-01
公開日2004-09-09
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of a Human Inositol 1,4,5-Trisphosphate 3-Kinase; Substrate Binding Reveals Why It is not a Phosphoinositide 3-Kinase
Mol.Cell, 15, 2004
2M1U
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BU of 2m1u by Molmil
Solution structure of the small dictyostelium discoideium myosin light chain mlcb provides insights into iq-motif recognition of class i myosin myo1b
分子名称: myosin light chain MlcB
著者Liburd, J, Chitayat, S, Crawley, S.W, Denis, C.M, Cote, G.P, Smith, S.P.
登録日2012-12-06
公開日2013-12-11
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure of the small Dictyostelium discoideum myosin light chain MlcB provides insights into MyoB IQ motif recognition.
J.Biol.Chem., 289, 2014
1W7J
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BU of 1w7j by Molmil
Crystal Structure Of Myosin V Motor With Essential Light Chain + ADP-BeFx - Near Rigor
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, ...
著者Coureux, P.-D, Sweeney, H.L, Houdusse, A.
登録日2004-09-03
公開日2005-02-22
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Three Myosin V Structures Delineate Essential Features of Chemo-Mechanical Transduction
Embo J., 23, 2004
1WGP
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BU of 1wgp by Molmil
Solution structure of the cNMP-binding domain from Arabidopsis thaliana cyclic nucleotide-regulated ion channel
分子名称: Probable cyclic nucleotide-gated ion channel 6
著者Chikayama, E, Nameki, N, Kigawa, T, Koshiba, S, Inoue, M, Tomizawa, T, Kobayashi, N, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2004-05-28
公開日2004-11-28
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the cNMP-binding domain from Arabidopsis thaliana cyclic nucleotide-regulated ion channel
To be Published
1WKU
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BU of 1wku by Molmil
High resolution structure of the human alpha-actinin isoform 3
分子名称: Alpha-actinin 3
著者Franzot, G, Sjoblom, B, Gautel, M, Djinovic Carugo, K.
登録日2004-06-08
公開日2005-05-17
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The crystal structure of the actin binding domain from alpha-actinin in its closed conformation: structural insight into phospholipid regulation of alpha-actinin
J.Mol.Biol., 348, 2005
1WAA
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BU of 1waa by Molmil
IG27 protein domain
分子名称: TITIN, ZINC ION
著者Vega, M.C, Valencia, L, Zou, P, Wilmanns, M.
登録日2004-10-25
公開日2006-07-05
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Mechanical Network in Titin Immunoglobulin from Force Distribution Analysis.
Plos Comput.Biol., 5, 2009
1E6H
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BU of 1e6h by Molmil
A-SPECTRIN SH3 DOMAIN A11V, M25I, V44I, V58L MUTANTS
分子名称: SPECTRIN ALPHA CHAIN
著者Vega, M.C, Serrano, L.
登録日2000-08-17
公開日2002-05-23
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Conformational Strain in the Hydrophobic Core and its Implications for Protein Folding and Design
Nat.Struct.Biol., 9, 2002
2M8U
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BU of 2m8u by Molmil
Solution structure of the Dictyostelium discodieum Myosin Light Chain, MlcC
分子名称: Myosin Light Chain, MlcC
著者Liburd, J.D, Miller, E, Langelaan, D, Chitayat, S, Crawley, S.W, Cote, G.P, Smith, S.P.
登録日2013-05-28
公開日2014-12-24
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Structure of the Single-lobe Myosin Light Chain C in Complex with the Light Chain-binding Domains of Myosin-1C Provides Insights into Divergent IQ Motif Recognition.
J.Biol.Chem., 291, 2016
1WY9
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BU of 1wy9 by Molmil
Crystal structure of microglia-specific protein, Iba1
分子名称: Allograft inflammatory factor 1, CALCIUM ION
著者Yamada, M, Imai, Y, Kohsaka, S, Kamitori, S.
登録日2005-02-09
公開日2006-02-21
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献X-ray Structures of the Microglia/Macrophage-specific Protein Iba1 from Human and Mouse Demonstrate Novel Molecular Conformation Change Induced by Calcium binding
J.Mol.Biol., 364, 2006
1UUE
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BU of 1uue by Molmil
a-SPECTRIN SH3 DOMAIN (V44T, D48G MUTANT)
分子名称: SPECTRIN ALPHA CHAIN
著者Vega, M.C, Fernandez, A, Wilmanns, M, Serrano, L.
登録日2003-12-18
公開日2004-02-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Solvation in Protein Folding Analysis: Combination of Theoretical and Experimental Approaches
Proc.Natl.Acad.Sci.USA, 101, 2004
4RAG
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BU of 4rag by Molmil
CRYSTAL STRUCTURE of PPC2A-D38K
分子名称: MANGANESE (II) ION, Protein phosphatase 1A
著者Pan, C, Tang, J.Y, Xu, Y.F, Xiao, P, Liu, H.D, Wang, H.A, Wang, W.B, Meng, F.G, Yu, X, Sun, J.P.
登録日2014-09-10
公開日2015-08-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献The catalytic role of the M2 metal ion in PP2C alpha
Sci Rep, 5, 2015
2VRF
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BU of 2vrf by Molmil
CRYSTAL STRUCTURE OF THE HUMAN BETA-2-SYNTROPHIN PDZ DOMAIN
分子名称: 1,2-ETHANEDIOL, BETA-2-SYNTROPHIN
著者Sun, Z, Roos, A.K, Pike, A.C.W, Pilka, E.S, Cooper, C, Elkins, J.M, Murray, J, Arrowsmith, C.H, Doyle, D, Edwards, A, von Delft, F, Bountra, C, Oppermann, U.
登録日2008-03-31
公開日2008-04-22
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of the Human Beta-2-Syntrophin Pdz Domain
To be Published
2WWM
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Crystal structure of the Titin M10-Obscurin like 1 Ig complex in space group P1
分子名称: OBSCURIN-LIKE PROTEIN 1, TITIN
著者Pernigo, S, Fukuzawa, A, Gautel, M, Steiner, R.A.
登録日2009-10-26
公開日2010-02-16
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Insight Into M-Band Assembly and Mechanics from the Titin-Obscurin-Like-1 Complex.
Proc.Natl.Acad.Sci.USA, 107, 2010

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