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7RMP
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BU of 7rmp by Molmil
Structure of ACLY D1026A - substrates-asym
分子名称: (3S)-citryl-Coenzyme A, ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, ...
著者Wei, X, Marmorstein, R.
登録日2021-07-28
公開日2023-05-10
最終更新日2025-05-28
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Allosteric role of the citrate synthase homology domain of ATP citrate lyase.
Nat Commun, 14, 2023
6UI9
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Structure of human ATP citrate lyase in complex with acetyl-CoA and oxaloacetate
分子名称: ACETYL COENZYME *A, ACLY, OXALOACETATE ION
著者Wei, X, Marmorstein, R.
登録日2019-09-30
公開日2019-12-25
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Molecular basis for acetyl-CoA production by ATP-citrate lyase
Nat.Struct.Mol.Biol., 27, 2020
5ZE9
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BU of 5ze9 by Molmil
Crystal structure of AMP-PNP bound mutant A3B3 complex from Enterococcus hirae V-ATPase
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, MAGNESIUM ION, ...
著者Maruyama, S, Suzuki, K, Sasaki, H, Mizutani, K, Saito, Y, Imai, F.L, Ishizuka-Katsura, Y, Shirouzu, M, Ichiro, Y, Murata, T.
登録日2018-02-27
公開日2019-02-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.102 Å)
主引用文献Metastable asymmetrical structure of a shaftless V1motor.
Sci Adv, 5, 2019
8G5C
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BU of 8g5c by Molmil
Structure of ACLY-D1026A-substrates, local refinement of ASH domain
分子名称: (3S)-citryl-Coenzyme A, ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, ...
著者Xuepeng, W, Ronen, M.
登録日2023-02-12
公開日2023-05-10
最終更新日2025-05-14
実験手法ELECTRON MICROSCOPY (2.2 Å)
主引用文献Allosteric role of the citrate synthase homology domain of ATP citrate lyase.
Nat Commun, 14, 2023
8G1F
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BU of 8g1f by Molmil
Structure of ACLY-D1026A-products
分子名称: (3S)-citryl-Coenzyme A, ACETYL COENZYME *A, ADENOSINE-5'-DIPHOSPHATE, ...
著者Wei, X, Marmorstein, R.
登録日2023-02-02
公開日2023-05-10
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献Allosteric role of the citrate synthase homology domain of ATP citrate lyase.
Nat Commun, 14, 2023
8G5D
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BU of 8g5d by Molmil
Structure of ACLY-D1026A-products, local refinement of ASH domain
分子名称: (3S)-citryl-Coenzyme A, ACETYL COENZYME *A, ADENOSINE-5'-DIPHOSPHATE, ...
著者Wei, X, Marmorstein, R.
登録日2023-02-13
公開日2023-05-10
最終更新日2025-05-14
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Allosteric role of the citrate synthase homology domain of ATP citrate lyase.
Nat Commun, 14, 2023
8G1E
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BU of 8g1e by Molmil
Structure of ACLY-D1026A-products-asym
分子名称: (3S)-citryl-Coenzyme A, ACETYL COENZYME *A, ADENOSINE-5'-DIPHOSPHATE, ...
著者Wei, X, Marmorstein, R.
登録日2023-02-02
公開日2023-05-10
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Allosteric role of the citrate synthase homology domain of ATP citrate lyase.
Nat Commun, 14, 2023
7D4U
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BU of 7d4u by Molmil
ATP complex with double mutant cyclic trinucleotide synthase CdnD
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Cyclic AMP-AMP-GMP synthase
著者Yang, C.-S, Hou, M.-H, Tsai, C.-L, Wang, Y.-C, Ko, T.-P, Chen, Y.
登録日2020-09-24
公開日2021-03-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure and functional implication of a bacterial cyclic AMP-AMP-GMP synthetase.
Nucleic Acids Res., 49, 2021
7L1J
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Mycobacterium tuberculosis dethiobiotin synthetase in complex with Tetrazole 1
分子名称: ATP-dependent dethiobiotin synthetase BioD, GLYCEROL, SULFATE ION, ...
著者Pederick, J.L, Bruning, J.B.
登録日2020-12-14
公開日2021-10-27
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Inhibition of Mycobacterium tuberculosis Dethiobiotin Synthase ( Mt DTBS): Toward Next-Generation Antituberculosis Agents.
Acs Chem.Biol., 16, 2021
5UDR
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BU of 5udr by Molmil
LarE, a sulfur transferase involved in synthesis of the cofactor for lactate racemase in complex with nicotinamide mononucleotid NMN
分子名称: ATP-utilizing enzyme of the PP-loopsuperfamily, BETA-NICOTINAMIDE RIBOSE MONOPHOSPHATE, MANGANESE (II) ION
著者Fellner, M, Desguin, B, Hausinger, R.P, Hu, J.
登録日2016-12-28
公開日2017-08-23
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Structural insights into the catalytic mechanism of a sacrificial sulfur insertase of the N-type ATP pyrophosphatase family, LarE.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5UNM
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BU of 5unm by Molmil
LarE, a sulfur transferase involved in synthesis of the cofactor for lactate racemase, substrate free form with flexible loop
分子名称: ATP-utilizing enzyme of the PP-loopsuperfamily, PHOSPHATE ION
著者Fellner, M, Desguin, B, Hausinger, R.P, Hu, J.
登録日2017-01-31
公開日2017-08-23
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Structural insights into the catalytic mechanism of a sacrificial sulfur insertase of the N-type ATP pyrophosphatase family, LarE.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
8YNQ
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BU of 8ynq by Molmil
ATP-grasp peptide ligase from Streptomyces
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ...
著者Xu, M.J, Yan, Y.Q.
登録日2024-03-11
公開日2025-02-19
最終更新日2025-02-26
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structural Insights into the Substrate Recognition Mechanism of an ATP-Grasp Peptide-Ligase Producing Diverse Dipeptides Containing Unnatural Amino Acids
Acs Catalysis, 15, 2025
6LCC
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BU of 6lcc by Molmil
Crystal structure of AaTPS apo
分子名称: AaTPS
著者He, H, Mori, T, Abe, I.
登録日2019-11-18
公開日2020-07-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of AaTPS
Nat Commun, 2020
6LCD
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BU of 6lcd by Molmil
Crystal structure of AaTPS with PPi
分子名称: AaTPS, FARNESYL DIPHOSPHATE, MAGNESIUM ION
著者He, H, Mori, T, Abe, I.
登録日2019-11-18
公開日2020-07-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of AaTPS
Nat Commun, 2020
4LJ2
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BU of 4lj2 by Molmil
Crystal structure of chorismate synthase from Acinetobacter baumannii at 3.15A resolution
分子名称: Chorismate synthase
著者Chaudhary, A, Singh, N, Kaushik, S, Tyagi, T.K, Sinha, M, Kaur, P, Sharma, S, Singh, T.P.
登録日2013-07-04
公開日2013-07-24
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Crystal structure of chorismate synthase from Acinetobacter baumannii at 3.15A resolution
To be Published
1U9Z
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BU of 1u9z by Molmil
Crystal Structure of Phosphoribosyl Diphosphate Synthase Complexed with AMP and Ribose 5-Phosphate
分子名称: ADENOSINE MONOPHOSPHATE, RIBOSE-5-PHOSPHATE, Ribose-phosphate pyrophosphokinase
著者Kadziola, A, Johansson, E, Jepsen, C.H, McGuire, J, Larsen, S, Hove-Jensen, B.
登録日2004-08-11
公開日2005-08-23
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Novel class III phosphoribosyl diphosphate synthase: structure and properties of the tetrameric, phosphate-activated, non-allosterically inhibited enzyme from Methanocaldococcus jannaschii
J.Mol.Biol., 354, 2005
1U9Y
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BU of 1u9y by Molmil
Crystal Structure of Phosphoribosyl Diphosphate Synthase from Methanocaldococcus jannaschii
分子名称: Ribose-phosphate pyrophosphokinase
著者Kadziola, A, Johansson, E, Jepsen, C.H, McGuire, J, Larsen, S, Hove-Jensen, B.
登録日2004-08-11
公開日2005-08-23
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Novel class III phosphoribosyl diphosphate synthase: structure and properties of the tetrameric, phosphate-activated, non-allosterically inhibited enzyme from Methanocaldococcus jannaschii
J.Mol.Biol., 354, 2005
5JM8
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BU of 5jm8 by Molmil
The structure of ATP-bound aerobactin synthetase IucA from a hypervirulent pathotype of Klebsiella pneumoniae
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Aerobactin synthase IucA, MAGNESIUM ION
著者Bailey, D.C, Drake, E.J, Gulick, A.M.
登録日2016-04-28
公開日2016-06-15
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural and Functional Characterization of Aerobactin Synthetase IucA from a Hypervirulent Pathotype of Klebsiella pneumoniae.
Biochemistry, 55, 2016
3SAY
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BU of 3say by Molmil
Crystal structure of human glycogen synthase kinase 3 beta (GSK3b) in complex with inhibitor 142
分子名称: (3Z)-N,N-diethyl-3-[(3E)-3-(hydroxyimino)-1,3-dihydro-2H-indol-2-ylidene]-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide, (4S)-2-METHYL-2,4-PENTANEDIOL, FORMIC ACID, ...
著者Mazanetz, M.P, Cheng, R.K.Y, Rowan, F, Laughton, C.A, Barker, J.J, Fischer, P.M.
登録日2011-06-03
公開日2012-06-13
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.231 Å)
主引用文献Crystal structure of human glycogen synthase kinase 3 beta (GSK3b) in complex with inhibitor 142
To be Published
3SD0
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BU of 3sd0 by Molmil
Identification of a Glycogen Synthase Kinase-3b Inhibitor that Attenuates Hyperactivity in CLOCK Mutant Mice
分子名称: 3-(5-fluoro-6-iodo-1-methyl-1H-indol-3-yl)-4-(7-methoxy-1-benzofuran-3-yl)-1H-pyrrole-2,5-dione, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Glycogen synthase kinase-3 beta
著者Mesecar, A.M, Walters, R.L.
登録日2011-06-08
公開日2011-08-03
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Identification of a Glycogen Synthase Kinase-3b Inhibitor that Attenuates Hyperactivity in CLOCK Mutant Mice
To be Published
8AT1
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BU of 8at1 by Molmil
CRYSTAL STRUCTURES OF ASPARTATE CARBAMOYLTRANSFERASE LIGATED WITH PHOSPHONOACETAMIDE, MALONATE, AND CTP OR ATP AT 2.8-ANGSTROMS RESOLUTION AND NEUTRAL P*H
分子名称: ASPARTATE CARBAMOYLTRANSFERASE (R STATE), CATALYTIC CHAIN, ASPARTATE CARBAMOYLTRANSFERASE REGULATORY CHAIN, ...
著者Gouaux, J.E, Stevens, R.C, Lipscomb, W.N.
登録日1989-09-22
公開日1990-10-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structures of aspartate carbamoyltransferase ligated with phosphonoacetamide, malonate, and CTP or ATP at 2.8-A resolution and neutral pH.
Biochemistry, 29, 1990
3S7Y
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BU of 3s7y by Molmil
Crystal structure of mmNAGS in Space Group P3121 at 4.3 A resolution
分子名称: N-acetylglutamate kinase / N-acetylglutamate synthase
著者Shi, D, Li, Y, Cabrera-Luque, J, Jin, Z, Yu, X, Allewell, N.M, Tuchman, M.
登録日2011-05-27
公開日2012-04-18
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (4.3077 Å)
主引用文献A Novel N-acetylglutamate synthase architecture revealed by the crystal structure of the bifunctional enzyme from Maricaulis maris.
Plos One, 6, 2011
8I9O
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BU of 8i9o by Molmil
ecCTPS filament bound with CTP, NADH, DON
分子名称: 5-OXO-L-NORLEUCINE, ADENINE, CTP synthase, ...
著者Guo, C.J, Liu, J.L.
登録日2023-02-07
公開日2024-02-14
最終更新日2024-07-24
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Filamentation and inhibition of prokaryotic CTP synthase with ligands.
Mlife, 3, 2024
7Z17
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BU of 7z17 by Molmil
E. coli C-P lyase bound to a PhnK ABC dimer in an open conformation
分子名称: Alpha-D-ribose 1-methylphosphonate 5-phosphate C-P lyase, Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnG, Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnH, ...
著者Amstrup, S.K, Sofos, N, Karlsen, J.L, Skjerning, R.B, Boesen, T, Enghild, J.J, Hove-Jensen, B, Brodersen, D.E.
登録日2022-02-24
公開日2022-05-25
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (2.57 Å)
主引用文献Structural remodelling of the carbon-phosphorus lyase machinery by a dual ABC ATPase.
Nat Commun, 14, 2023
6LP1
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BU of 6lp1 by Molmil
Crystal structure of acetate:succinate CoA transferase (ASCT) from Trypanosoma brucei.
分子名称: CALCIUM ION, GLYCEROL, Succinyl-CoA:3-ketoacid-coenzyme A transferase
著者Mochizuki, K, Inaoka, D.K, Shiba, T, Fukuda, K, Kurasawa, H, Mazet, M, Millerioux, Y, Bringaud, F, Boshart, M, Balogun, E.O, Harada, S, Hirayama, K, Kita, K.
登録日2020-01-08
公開日2020-10-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献The ASCT/SCS cycle fuels mitochondrial ATP and acetate production in Trypanosoma brucei.
Biochim Biophys Acta Bioenerg, 1861, 2020

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件を2025-07-09に公開中

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