5L6T
| CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH A QUINOLINE OLIGOAMIDE FOLDAMER | 分子名称: | 8-azanyl-4-(2-ethylbutoxy)quinoline-2-carbaldehyde, 8-azanyl-4-(2-hydroxy-2-oxoethyloxy)quinoline-2-carboxylic acid, 8-azanyl-4-(3-azanylpropoxy)quinoline-2-carboxylic acid, ... | 著者 | Vallade, M, Langlois d'Estaintot, B, Granier, T, Huc, I. | 登録日 | 2016-05-31 | 公開日 | 2017-06-21 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH A QUINOLINE OLIGOAMIDE FOLDAMER To Be Published
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5L70
| CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH A QUINOLINE OLIGOAMIDE FOLDAMER | 分子名称: | 8-azanyl-4-(2-hydroxy-2-oxoethyloxy)quinoline-2-carboxylic acid, 8-azanyl-4-(3-azanylpropoxy)quinoline-2-carboxylic acid, 8-azanyl-4-[2-(hydroxymethyl)-3-oxidanyl-propoxy]quinoline-2-carbaldehyde, ... | 著者 | Vallade, M, Langlois d'Estaintot, B, Granier, T, Huc, I. | 登録日 | 2016-06-01 | 公開日 | 2017-06-21 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | CRYSTAL STRUCTURE OF HUMAN CARBONIC ANHYDRASE II IN COMPLEX WITH A QUINOLINE OLIGOAMIDE FOLDAMER To Be Published
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6UBP
| Crystal structure of a photochemical intermediate of human indoleamine 2,3-dioxygenase 1 in complex with carbon monoxide and tryptophan | 分子名称: | CARBON MONOXIDE, Indoleamine 2,3-dioxygenase 1, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Pham, K.N, Yeh, S.R. | 登録日 | 2019-09-12 | 公開日 | 2021-02-03 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Conformational Plasticity in Human Heme-Based Dioxygenases. J.Am.Chem.Soc., 143, 2021
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6TYB
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5O4M
| Fresh crystals of HcgC from Methanococcus maripaludis cocrystallized with SAH and pyridinol | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 6-carboxy methyl-4-hydroxy-2-pyridinol, DIMETHYL SULFOXIDE, ... | 著者 | Wagner, T, Bai, L, Xu, T, Hu, X, Ermler, U, Shima, S. | 登録日 | 2017-05-29 | 公開日 | 2017-07-19 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A Water-Bridged H-Bonding Network Contributes to the Catalysis of the SAM-Dependent C-Methyltransferase HcgC. Angew. Chem. Int. Ed. Engl., 56, 2017
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3HRM
| Crystal structure of Staphylococcus aureus protein SarZ in sulfenic acid form | 分子名称: | HTH-type transcriptional regulator sarZ | 著者 | Poor, C.B, Duguid, E, Rice, P.A, He, C. | 登録日 | 2009-06-09 | 公開日 | 2009-07-07 | 最終更新日 | 2017-11-01 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal structures of the reduced, sulfenic acid, and mixed disulfide forms of SarZ, a redox active global regulator in Staphylococcus aureus. J.Biol.Chem., 284, 2009
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5G5L
| RNA polymerase I-Rrn3 complex at 4.8 A resolution | 分子名称: | DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA12, DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135, DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA14, ... | 著者 | Engel, C, Plitzko, J, Cramer, P. | 登録日 | 2016-05-26 | 公開日 | 2016-07-27 | 最終更新日 | 2018-10-24 | 実験手法 | ELECTRON MICROSCOPY (4.8 Å) | 主引用文献 | RNA Polymerase I-Rrn3 Complex at 4.8 A Resolution Nat.Commun., 7, 2016
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6U30
| The crystal structure of 4-pyridin-3-ylbenzoate-bound CYP199A4 | 分子名称: | 4-(pyridin-3-yl)benzoic acid, ACETATE ION, CHLORIDE ION, ... | 著者 | Podgorski, M.N, Bruning, J.B, Bell, S.G. | 登録日 | 2019-08-21 | 公開日 | 2020-02-19 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.655 Å) | 主引用文献 | Biophysical Techniques for Distinguishing Ligand Binding Modes in Cytochrome P450 Monooxygenases. Biochemistry, 59, 2020
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5KSO
| hMiro1 C-domain GDP-Pi Complex P3121 Crystal Form | 分子名称: | GUANOSINE-5'-DIPHOSPHATE, Mitochondrial Rho GTPase 1, PHOSPHATE ION | 著者 | Klosowiak, J.L, Focia, P.J, Rice, S.E, Freymann, D.M. | 登録日 | 2016-07-08 | 公開日 | 2016-09-21 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Structural insights into Parkin substrate lysine targeting from minimal Miro substrates. Sci Rep, 6, 2016
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4A7L
| Structure of the Actin-Tropomyosin-Myosin Complex (rigor ATM 1) | 分子名称: | ACTIN, ALPHA SKELETON MUSCLE, ADENOSINE-5'-DIPHOSPHATE, ... | 著者 | Behrmann, E, Mueller, M, Penczek, P.A, Mannherz, H.G, Manstein, D.J, Raunser, S. | 登録日 | 2011-11-14 | 公開日 | 2012-08-01 | 最終更新日 | 2019-10-23 | 実験手法 | ELECTRON MICROSCOPY (8.1 Å) | 主引用文献 | Structure of the Rigor Actin-Tropomyosin-Myosin Complex. Cell(Cambridge,Mass.), 150, 2012
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2AFM
| Crystal structure of human glutaminyl cyclase at pH 6.5 | 分子名称: | Glutaminyl-peptide cyclotransferase, SULFATE ION, ZINC ION | 著者 | Huang, K.F, Liu, Y.L, Cheng, W.J, Ko, T.P, Wang, A.H.J. | 登録日 | 2005-07-26 | 公開日 | 2005-08-23 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | 主引用文献 | Crystal structures of human glutaminyl cyclase, an enzyme responsible for protein N-terminal pyroglutamate formation Proc.Natl.Acad.Sci.Usa, 102, 2005
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5KU1
| hMiro1 EF hand and cGTPase domains in the GDP-bound state | 分子名称: | CHLORIDE ION, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Klosowiak, J.L, Focia, P.J, Rice, S.E, Freymann, D.M. | 登録日 | 2016-07-12 | 公開日 | 2016-09-21 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.501 Å) | 主引用文献 | Structural insights into Parkin substrate lysine targeting from minimal Miro substrates. Sci Rep, 6, 2016
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5HQ3
| Stable, high-expression variant of human acetylcholinesterase | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Acetylcholinesterase, O-ETHYLMETHYLPHOSPHONIC ACID ESTER GROUP | 著者 | Goldenzweig, A, Goldsmith, M, Hill, S.E, Gertman, O, Laurino, P, Ashani, Y, Dym, O, Albeck, S, Unger, T, Prilusky, J, Lieberman, R.L, Aharoni, A, Silman, I, Sussman, J.L, Tawfik, D.S, Fleishman, S.J. | 登録日 | 2016-01-21 | 公開日 | 2016-07-27 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Automated Structure- and Sequence-Based Design of Proteins for High Bacterial Expression and Stability. Mol.Cell, 63, 2016
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3I6D
| Crystal structure of PPO from bacillus subtilis with AF | 分子名称: | 5-[2-CHLORO-4-(TRIFLUOROMETHYL)PHENOXY]-2-NITROBENZOIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, PHOSPHATE ION, ... | 著者 | Shen, Y. | 登録日 | 2009-07-06 | 公開日 | 2009-12-08 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural insight into unique properties of protoporphyrinogen oxidase from Bacillus subtilis J.Struct.Biol., 170, 2010
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4B1V
| Structure of the Phactr1 RPEL-N domain bound to G-actin | 分子名称: | 1,2-ETHANEDIOL, ACTIN, ALPHA SKELETAL MUSCLE, ... | 著者 | Mouilleron, S, Wiezlak, M, O'Reilly, N, Treisman, R, McDonald, N.Q. | 登録日 | 2012-07-12 | 公開日 | 2012-11-07 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structures of the Phactr1 RPEL domain and RPEL motif complexes with G-actin reveal the molecular basis for actin binding cooperativity. Structure, 20, 2012
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4B2B
| Structure of the factor Xa-like trypsin variant triple-Ala (TGPA) in complex with eglin C | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, CATIONIC TRYPSIN, ... | 著者 | Menzel, A, Neumann, P, Stubbs, M.T. | 登録日 | 2012-07-13 | 公開日 | 2012-08-01 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | 主引用文献 | Thermodynamic signatures in macromolecular interactions involving conformational flexibility. Biol.Chem., 395, 2014
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5DZX
| Protocadherin beta 6 extracellular cadherin domains 1-4 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Protocadherin beta 6, ... | 著者 | Goodman, K.M, Mannepalli, S, Bahna, F, Honig, B, Shapiro, L. | 登録日 | 2015-09-26 | 公開日 | 2016-05-04 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.879 Å) | 主引用文献 | Structural Basis of Diverse Homophilic Recognition by Clustered alpha- and beta-Protocadherins. Neuron, 90, 2016
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4ARI
| Ternary complex of E. coli leucyl-tRNA synthetase, tRNA(leu) and the benzoxaborole AN2679 in the editing conformation | 分子名称: | GLYCEROL, LEUCINE--TRNA LIGASE, MAGNESIUM ION, ... | 著者 | Palencia, A, Crepin, T, Vu, M.T, Lincecum Jr, T.L, Martinis, S.A, Cusack, S. | 登録日 | 2012-04-24 | 公開日 | 2012-06-13 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | Structural Dynamics of the Aminoacylation and Proofreading Functional Cycle of Bacterial Leucyl-tRNA Synthetase Nat.Struct.Mol.Biol., 19, 2012
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5HGO
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5DZY
| Protocadherin beta 8 extracellular cadherin domains 1-4 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Pcdhb8 protein, ... | 著者 | Goodman, K.M, Bahna, F, Mannepalli, S, Honig, B, Shapiro, L. | 登録日 | 2015-09-26 | 公開日 | 2016-05-04 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Structural Basis of Diverse Homophilic Recognition by Clustered alpha- and beta-Protocadherins. Neuron, 90, 2016
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6H1M
| Neutron structure of Lactobacillus brevis alcohol dehydrogenase | 分子名称: | MAGNESIUM ION, MANGANESE (II) ION, R-specific alcohol dehydrogenase | 著者 | Hermann, J, Nowotny, P, Schrader, T.E, Biggel, P, Hekmat, D, Weuster-Botz, D. | 登録日 | 2018-07-12 | 公開日 | 2018-12-12 | 最終更新日 | 2024-01-24 | 実験手法 | NEUTRON DIFFRACTION (2.15 Å) | 主引用文献 | Neutron and X-ray crystal structures of Lactobacillus brevis alcohol dehydrogenase reveal new insights into hydrogen-bonding pathways. Acta Crystallogr F Struct Biol Commun, 74, 2018
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3LU8
| Human serum albumin in complex with compound 3 | 分子名称: | N-[5-(5-{[(2,4-dimethyl-1,3-thiazol-5-yl)sulfonyl]amino}-6-fluoropyridin-3-yl)-4-methyl-1,3-thiazol-2-yl]acetamide, Serum albumin | 著者 | Buttar, D, Colclough, N, Gerhardt, S, MacFaul, P.A, Phillips, S.D, Plowright, A, Whittamore, P, Tam, K, Maskos, K, Steinbacher, S, Steuber, H. | 登録日 | 2010-02-17 | 公開日 | 2010-10-27 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | A combined spectroscopic and crystallographic approach to probing drug-human serum albumin interactions Bioorg.Med.Chem., 18, 2010
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6UGJ
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6GZV
| Identification of a druggable VP1-VP3 interprotomer pocket in the capsid of enteroviruses | 分子名称: | 4-[[4-[1,3-bis(oxidanylidene)isoindol-2-yl]phenyl]sulfonylamino]benzoic acid, Capsid protein VP1, Capsid protein VP2, ... | 著者 | Geraets, J.A, Flatt, J.W, Domanska, A, Butcher, S.J. | 登録日 | 2018-07-05 | 公開日 | 2019-06-05 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | A novel druggable interprotomer pocket in the capsid of rhino- and enteroviruses. Plos Biol., 17, 2019
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6H0U
| Glycogen synthase kinase-3 beta (GSK3) complex with a covalent [1,2,4]triazolo[1,5-a][1,3,5]triazine inhibitor | 分子名称: | (2~{R})-3-[7-azanyl-5-(cyclohexylamino)-[1,2,4]triazolo[1,5-a][1,3,5]triazin-2-yl]-2-cyano-propanamide, CHLORIDE ION, GLYCEROL, ... | 著者 | Marcovich, I, Demitri, N, De Zorzi, R, Storici, P. | 登録日 | 2018-07-10 | 公開日 | 2019-05-15 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | A Triazolotriazine-Based Dual GSK-3 beta /CK-1 delta Ligand as a Potential Neuroprotective Agent Presenting Two Different Mechanisms of Enzymatic Inhibition. Chemmedchem, 14, 2019
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