6UBP

Crystal structure of a photochemical intermediate of human indoleamine 2,3-dioxygenase 1 in complex with carbon monoxide and tryptophan

Summary for 6UBP

Entry DOI	10.2210/pdb6ubp/pdb
Descriptor	Indoleamine 2,3-dioxygenase 1, PROTOPORPHYRIN IX CONTAINING FE, TRYPTOPHAN, ... (5 entities in total)
Functional Keywords	human indoleamine 2, 3-dioxygenase x-ray photolysis of co and tryptophan, oxidoreductase
Biological source	Homo sapiens (Human)
Total number of polymer chains	2
Total formula weight	97281.28
Authors	Pham, K.N.,Yeh, S.R. (deposition date: 2019-09-12, release date: 2021-02-03, Last modification date: 2023-10-11)
Primary citation	Pham, K.N.,Lewis-Ballester, A.,Yeh, S.R. Conformational Plasticity in Human Heme-Based Dioxygenases. J.Am.Chem.Soc., 143:1836-1845, 2021 Cited by PubMed: 33373218 DOI: 10.1021/jacs.0c09970 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.95 Å)

Structure validation