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6GZV

Identification of a druggable VP1-VP3 interprotomer pocket in the capsid of enteroviruses

Summary for 6GZV
Entry DOI10.2210/pdb6gzv/pdb
EMDB information0103
DescriptorCapsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... (5 entities in total)
Functional Keywordsinhibitor, complex, virus
Biological sourceCoxsackievirus B3 (strain Nancy)
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Total number of polymer chains4
Total formula weight94674.45
Authors
Geraets, J.A.,Flatt, J.W.,Domanska, A.,Butcher, S.J. (deposition date: 2018-07-05, release date: 2019-06-05, Last modification date: 2019-06-19)
Primary citationAbdelnabi, R.,Geraets, J.A.,Ma, Y.,Mirabelli, C.,Flatt, J.W.,Domanska, A.,Delang, L.,Jochmans, D.,Kumar, T.A.,Jayaprakash, V.,Sinha, B.N.,Leyssen, P.,Butcher, S.J.,Neyts, J.
A novel druggable interprotomer pocket in the capsid of rhino- and enteroviruses.
Plos Biol., 17:e3000281-e3000281, 2019
Cited by
PubMed: 31185007
DOI: 10.1371/journal.pbio.3000281
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (4 Å)
Structure validation

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