6GZV
Identification of a druggable VP1-VP3 interprotomer pocket in the capsid of enteroviruses
Summary for 6GZV
Entry DOI | 10.2210/pdb6gzv/pdb |
EMDB information | 0103 |
Descriptor | Capsid protein VP1, Capsid protein VP2, Capsid protein VP3, ... (5 entities in total) |
Functional Keywords | inhibitor, complex, virus |
Biological source | Coxsackievirus B3 (strain Nancy) More |
Total number of polymer chains | 4 |
Total formula weight | 94674.45 |
Authors | Geraets, J.A.,Flatt, J.W.,Domanska, A.,Butcher, S.J. (deposition date: 2018-07-05, release date: 2019-06-05, Last modification date: 2019-06-19) |
Primary citation | Abdelnabi, R.,Geraets, J.A.,Ma, Y.,Mirabelli, C.,Flatt, J.W.,Domanska, A.,Delang, L.,Jochmans, D.,Kumar, T.A.,Jayaprakash, V.,Sinha, B.N.,Leyssen, P.,Butcher, S.J.,Neyts, J. A novel druggable interprotomer pocket in the capsid of rhino- and enteroviruses. Plos Biol., 17:e3000281-e3000281, 2019 Cited by PubMed: 31185007DOI: 10.1371/journal.pbio.3000281 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4 Å) |
Structure validation
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