6NWA
 
 | | The structure of the photosystem I IsiA super-complex | | 分子名称: | 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-DISTEAROYL-MONOGALACTOSYL-DIGLYCERIDE, BETA-CAROTENE, ... | | 著者 | Toporik, H, Li, J, Williams, D, Chiu, P.L, Mazor, Y. | | 登録日 | 2019-02-06 | | 公開日 | 2019-05-29 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.48 Å) | | 主引用文献 | The structure of the stress-induced photosystem I-IsiA antenna supercomplex.
Nat.Struct.Mol.Biol., 26, 2019
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8QSZ
 | | Structure of s. pombe RNA polymerase II in complex with DSIF and Rat1/Rai1 | | 分子名称: | 5'-3' exoribonuclease 2, DNA none template (34-MER), DNA template (40-MER), ... | | 著者 | Carrique, L, Kus, K, Vasiljeva, L, Grimes, J.M. | | 登録日 | 2023-10-12 | | 公開日 | 2024-10-23 | | 最終更新日 | 2025-01-22 | | 実験手法 | ELECTRON MICROSCOPY (2.67 Å) | | 主引用文献 | DSIF factor Spt5 coordinates transcription, maturation and exoribonucleolysis of RNA polymerase II transcripts.
Nat Commun, 16, 2025
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6O97
 | | Crystal structure of the Thermus thermophilus 70S ribosome in complex with propylamycin and bound to mRNA and A-, P-, and E-site tRNAs at 2.75A resolution | | 分子名称: | (1R,2R,3S,4R,6S)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-beta-L-idopyranosyl)-beta-D-ribofuranosyl]oxy}-3-hydroxyc yclohexyl 2-amino-2,4-dideoxy-4-propyl-alpha-D-glucopyranoside, 16S Ribosomal RNA, 23S Ribosomal RNA, ... | | 著者 | Matsushita, T, Sati, G.C, Kondasinghe, N, Pirrone, M.G, Kato, T, Waduge, P, Kumar, H.S, Sanchon, A.C, Dobosz-Bartoszek, M, Shcherbakov, D, Juhas, M, Hobbie, S.N, Schrepfer, T, Chow, C.S, Polikanov, Y.S, Schacht, J, Vasella, A, Bottger, E.C, Crich, D. | | 登録日 | 2019-03-13 | | 公開日 | 2019-04-17 | | 最終更新日 | 2025-03-19 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | Design, Multigram Synthesis, and in Vitro and in Vivo Evaluation of Propylamycin: A Semisynthetic 4,5-Deoxystreptamine Class Aminoglycoside for the Treatment of Drug-Resistant Enterobacteriaceae and Other Gram-Negative Pathogens.
J. Am. Chem. Soc., 141, 2019
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6NTA
 | | Modified ASL proline bound to Thermus thermophilus 70S (cognate) | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | 著者 | Hoffer, E.D, Maehigashi, T, Subaramanian, S, Hong, S, Dunham, C.M. | | 登録日 | 2019-01-28 | | 公開日 | 2020-10-14 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon-anticodon pairing.
Elife, 9, 2020
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6JXJ
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8OGJ
 | | Structure of Candida albicans 80S ribosome in complex with mefloquine | | 分子名称: | (11R,12S)- Mefloquine, 18S ribosomal RNA, 25S ribosomal RNA, ... | | 著者 | Kolosova, O, Zgadzay, Y, Stetsenko, A, Guskov, A, Yusupov, M. | | 登録日 | 2023-03-20 | | 公開日 | 2024-10-02 | | 最終更新日 | 2025-04-30 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Mechanism of read-through enhancement by aminoglycosides and mefloquine
Proc.Natl.Acad.Sci.USA, 2025
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8OH6
 | | Crystal structure of the Candida albicans 80S ribosome in complex with Paromomycin (500umol) | | 分子名称: | 18S, 25S (gene name XR_002086444.1), 3-O-acetyl-2-O-(3-O-acetyl-6-deoxy-beta-D-glucopyranosyl)-6-deoxy-1-O-{[(2R,2'S,3a'R,4''S,5''R,6'S,7a'S)-5''-methyl-4''-{[(2E)-3-phenylprop-2-enoyl]oxy}decahydrodispiro[oxirane-2,3'-[1]benzofuran-2',2''-pyran]-6'-yl]carbonyl}-beta-D-glucopyranose, ... | | 著者 | Kolosova, O, Zgadzay, Y, Yusupov, M. | | 登録日 | 2023-03-20 | | 公開日 | 2024-10-02 | | 最終更新日 | 2025-04-30 | | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | | 主引用文献 | Mechanism of read-through enhancement by aminoglycosides and mefloquine
Proc.Natl.Acad.Sci.USA, 2025
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5CKA
 | | Human beta-2 microglobulin double mutant W60G-N83V | | 分子名称: | ACETATE ION, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Sala, B.M, De Rosa, M, Bolognesi, M, Ricagno, S. | | 登録日 | 2015-07-15 | | 公開日 | 2016-05-18 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Rational design of mutations that change the aggregation rate of a protein while maintaining its native structure and stability.
Sci Rep, 6, 2016
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5CKG
 | | Human beta-2 microglobulin mutant V85E | | 分子名称: | ACETATE ION, Beta-2-microglobulin, GLYCEROL | | 著者 | Sala, B.M, De Rosa, M, Bolognesi, M, Ricagno, S. | | 登録日 | 2015-07-15 | | 公開日 | 2016-05-18 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Rational design of mutations that change the aggregation rate of a protein while maintaining its native structure and stability.
Sci Rep, 6, 2016
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6W9U
 | | Structure of human MAIT A-F7 TCR in complex with patient MR1-R9H-Ac-6-FP | | 分子名称: | 1-[[6-(1-$l^{1}-oxidanylethyl)-4-$l^{3}-oxidanylidene-2,3,6,8~{a}-tetrahydropteridin-2-yl]-$l^{2}-azanyl]ethanone, Beta-2-microglobulin, CHLORIDE ION, ... | | 著者 | Awad, W, Rossjohn, J. | | 登録日 | 2020-03-23 | | 公開日 | 2020-08-05 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | | 主引用文献 | Absence of mucosal-associated invariant T cells in a person with a homozygous point mutation in MR1 .
Sci Immunol, 5, 2020
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8OEQ
 | | Crystal structure of the Candida albicans 80S ribosome in complex with Paromomycin (250uM) | | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 3-O-acetyl-2-O-(3-O-acetyl-6-deoxy-beta-D-glucopyranosyl)-6-deoxy-1-O-{[(2R,2'S,3a'R,4''S,5''R,6'S,7a'S)-5''-methyl-4''-{[(2E)-3-phenylprop-2-enoyl]oxy}decahydrodispiro[oxirane-2,3'-[1]benzofuran-2',2''-pyran]-6'-yl]carbonyl}-beta-D-glucopyranose, ... | | 著者 | Kolosova, O, Zgadzay, Y, Yusupov, M. | | 登録日 | 2023-03-12 | | 公開日 | 2024-09-25 | | 最終更新日 | 2025-04-30 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Mechanism of read-through enhancement by aminoglycosides and mefloquine
Proc.Natl.Acad.Sci.USA, 2025
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8OI5
 | | Crystal structure of the Candida albicans 80S ribosome in complex with Paromomycin (2mM) | | 分子名称: | 18S, 25S, 3-O-acetyl-2-O-(3-O-acetyl-6-deoxy-beta-D-glucopyranosyl)-6-deoxy-1-O-{[(2R,2'S,3a'R,4''S,5''R,6'S,7a'S)-5''-methyl-4''-{[(2E)-3-phenylprop-2-enoyl]oxy}decahydrodispiro[oxirane-2,3'-[1]benzofuran-2',2''-pyran]-6'-yl]carbonyl}-beta-D-glucopyranose, ... | | 著者 | Kolosova, O, Zgadzay, Y, Yusupov, M. | | 登録日 | 2023-03-22 | | 公開日 | 2024-10-09 | | 最終更新日 | 2025-04-30 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Mechanism of read-through enhancement by aminoglycosides and mefloquine
Proc.Natl.Acad.Sci.USA, 2025
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8OJ3
 | | Crystal structure of the Candida albicans 80S ribosome in complex with geneticin G418 (rotated state) | | 分子名称: | 18S ribosomal RNA, 25S ribosomal RNA, 3-O-acetyl-2-O-(3-O-acetyl-6-deoxy-beta-D-glucopyranosyl)-6-deoxy-1-O-{[(2R,2'S,3a'R,4''S,5''R,6'S,7a'S)-5''-methyl-4''-{[(2E)-3-phenylprop-2-enoyl]oxy}decahydrodispiro[oxirane-2,3'-[1]benzofuran-2',2''-pyran]-6'-yl]carbonyl}-beta-D-glucopyranose, ... | | 著者 | Kolosova, O, Zgadzay, Y, Yusupov, M. | | 登録日 | 2023-03-23 | | 公開日 | 2024-10-09 | | 最終更新日 | 2025-04-30 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Mechanism of read-through enhancement by aminoglycosides and mefloquine
Proc.Natl.Acad.Sci.USA, 2025
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6OF6
 | | Crystal structure of tRNA^ Ala(GGC) bound to cognate 70S A-site | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | 著者 | Nguyen, H.A, Sunita, S, Dunham, C.M. | | 登録日 | 2019-03-28 | | 公開日 | 2020-06-24 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Disruption of evolutionarily correlated tRNA elements impairs accurate decoding.
Proc.Natl.Acad.Sci.USA, 117, 2020
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5CFH
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5COY
 | | Crystal structure of CC chemokine 5 (CCL5) | | 分子名称: | C-C motif chemokine 5, DI(HYDROXYETHYL)ETHER, PHOSPHATE ION, ... | | 著者 | Liang, W.G, Tang, W. | | 登録日 | 2015-07-20 | | 公開日 | 2016-04-13 | | 最終更新日 | 2024-11-20 | | 実験手法 | X-RAY DIFFRACTION (1.443 Å) | | 主引用文献 | Structural basis for oligomerization and glycosaminoglycan binding of CCL5 and CCL3.
Proc.Natl.Acad.Sci.USA, 113, 2016
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2RGX
 | | Crystal Structure of Adenylate Kinase from Aquifex Aeolicus in complex with Ap5A | | 分子名称: | Adenylate kinase, BIS(ADENOSINE)-5'-PENTAPHOSPHATE, ZINC ION | | 著者 | Thai, V, Wolf-Watz, M, Fenn, T, Pozharski, E, Wilson, M.A, Petsko, G.A, Kern, D. | | 登録日 | 2007-10-05 | | 公開日 | 2007-12-18 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Intrinsic motions along an enzymatic reaction trajectory.
Nature, 450, 2007
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8AC0
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8ABY
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8ABZ
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8AD1
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8ACP
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8A3D
 | | Human mature large subunit of the ribosome with eIF6 and homoharringtonine bound | | 分子名称: | (3beta)-O~3~-[(2R)-2,6-dihydroxy-2-(2-methoxy-2-oxoethyl)-6-methylheptanoyl]cephalotaxine, 28S ribosomal RNA, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... | | 著者 | Faille, A, Warren, A.J, Dent, K.C. | | 登録日 | 2022-06-08 | | 公開日 | 2023-03-08 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (1.67 Å) | | 主引用文献 | The chemical landscape of the human ribosome at 1.67 angstrom resolution.
Biorxiv, 2023
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4IS8
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5CMD
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