7LD3
 
 | | Cryo-EM structure of the human adenosine A1 receptor-Gi2-protein complex bound to its endogenous agonist and an allosteric ligand | | 分子名称: | ADENOSINE, Chimera protein of Muscarinic acetylcholine receptor M4 and Adenosine receptor A1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Draper-Joyce, C.J, Danev, R, Thal, D.M, Christopoulos, A, Glukhova, A. | | 登録日 | 2021-01-12 | | 公開日 | 2021-09-08 | | 最終更新日 | 2024-11-13 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Positive allosteric mechanisms of adenosine A 1 receptor-mediated analgesia.
Nature, 597, 2021
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7LD4
 | | Cryo-EM structure of the human adenosine A1 receptor-Gi2-protein complex bound to its endogenous agonist | | 分子名称: | ADENOSINE, Chimera protein of Muscarinic acetylcholine receptor M4 and Adenosine receptor A1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Draper-Joyce, C.J, Danev, R, Thal, D.M, Christopoulos, A, Glukhova, A. | | 登録日 | 2021-01-12 | | 公開日 | 2021-09-08 | | 最終更新日 | 2025-03-12 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Positive allosteric mechanisms of adenosine A 1 receptor-mediated analgesia.
Nature, 597, 2021
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5AYN
 | | Crystal structure of a bacterial homologue of iron transporter ferroportin in outward-facing state | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, POTASSIUM ION, Solute carrier family 39 (Iron-regulated transporter) | | 著者 | Taniguchi, R, Kato, H.E, Font, J, Deshpande, C.N, Ishitani, R, Jormakka, M, Nureki, O. | | 登録日 | 2015-08-25 | | 公開日 | 2015-11-04 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (2.202 Å) | | 主引用文献 | Outward- and inward-facing structures of a putative bacterial transition-metal transporter with homology to ferroportin
Nat Commun, 6, 2015
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6NDK
 | | Structure of ASLSufA6 A37.5 bound to the 70S A site | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | 著者 | Nguyen, H.T, Hoffer, E.D, Dunham, C.M. | | 登録日 | 2018-12-13 | | 公開日 | 2019-02-27 | | 最終更新日 | 2025-03-19 | | 実験手法 | X-RAY DIFFRACTION (3.64 Å) | | 主引用文献 | Importance of a tRNA anticodon loop modification and a conserved, noncanonical anticodon stem pairing intRNACGGProfor decoding
J. Biol. Chem., 294, 2019
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6ND5
 | | Crystal structure of the Thermus thermophilus 70S ribosome in complex with chloramphenicol and bound to mRNA and A-, P-, and E-site tRNAs at 2.60A resolution | | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Svetlov, M.S, Plessa, E, Chen, C.-W, Bougas, A, Krokidis, M.G, Dinos, G.P, Polikanov, Y.S. | | 登録日 | 2018-12-13 | | 公開日 | 2019-03-20 | | 最終更新日 | 2025-03-19 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | High-resolution crystal structures of ribosome-bound chloramphenicol and erythromycin provide the ultimate basis for their competition.
RNA, 25, 2019
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6ND6
 | | Crystal structure of the Thermus thermophilus 70S ribosome in complex with erythromycin and bound to mRNA and A-, P-, and E-site tRNAs at 2.85A resolution | | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Svetlov, M.S, Plessa, E, Chen, C.-W, Bougas, A, Krokidis, M.G, Dinos, G.P, Polikanov, Y.S. | | 登録日 | 2018-12-13 | | 公開日 | 2019-02-20 | | 最終更新日 | 2025-03-19 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | High-resolution crystal structures of ribosome-bound chloramphenicol and erythromycin provide the ultimate basis for their competition.
RNA, 25, 2019
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5AYO
 | | Crystal structure of a bacterial homologue of iron transporter ferroportin in inward-facing state | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, POTASSIUM ION, Solute carrier family 39 (Iron-regulated transporter), ... | | 著者 | Taniguchi, R, Kato, H.E, Font, J, Deshpande, C.N, Ishitani, R, Jormakka, M, Nureki, O. | | 登録日 | 2015-08-25 | | 公開日 | 2015-11-04 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Outward- and inward-facing structures of a putative bacterial transition-metal transporter with homology to ferroportin
Nat Commun, 6, 2015
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6N1D
 | | X-ray Crystal complex showing Spontaneous Ribosomal Translocation of mRNA and tRNAs into a Chimeric Hybrid State | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | 著者 | Noller, H.F, Donohue, J.P, Lancaster, L, Zhou, J. | | 登録日 | 2018-11-08 | | 公開日 | 2019-04-03 | | 最終更新日 | 2024-11-13 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Spontaneous ribosomal translocation of mRNA and tRNAs into a chimeric hybrid state.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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5AYM
 | | Crystal structure of a bacterial homologue of iron transporter ferroportin in outward-facing state with soaked iron | | 分子名称: | FE (II) ION, Solute carrier family 39 (Iron-regulated transporter) | | 著者 | Taniguchi, R, Kato, H.E, Font, J, Deshpande, C.N, Ishitani, R, Jormakka, M, Nureki, O. | | 登録日 | 2015-08-25 | | 公開日 | 2015-11-04 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Outward- and inward-facing structures of a putative bacterial transition-metal transporter with homology to ferroportin
Nat Commun, 6, 2015
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6ULK
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6IP8
 | | Cryo-EM structure of the HCV IRES dependently initiated CMV-stalled 80S ribosome (Structure iv) | | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | | 著者 | Yokoyama, T, Shigematsu, H, Shirouzu, M, Imataka, H, Ito, T. | | 登録日 | 2018-11-02 | | 公開日 | 2019-05-29 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | HCV IRES Captures an Actively Translating 80S Ribosome.
Mol.Cell, 74, 2019
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6NWY
 | | Modified tRNA(Pro) bound to Thermus thermophilus 70S (near-cognate) | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | 著者 | Hoffer, E.D, Subaramanian, S, Hong, S, Maehigashi, T, Dunham, C.M. | | 登録日 | 2019-02-07 | | 公開日 | 2020-10-14 | | 最終更新日 | 2024-12-25 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon-anticodon pairing.
Elife, 9, 2020
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6NUO
 | | Modified tRNA(Pro) bound to Thermus thermophilus 70S (cognate) | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | 著者 | Hoffer, E.D, Subaramanian, S, Hong, S, Maehigashi, T, Dunham, C.M. | | 登録日 | 2019-02-01 | | 公開日 | 2020-10-14 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon-anticodon pairing.
Elife, 9, 2020
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6IP6
 | | Cryo-EM structure of the CMV-stalled human 80S ribosome with HCV IRES (Structure iii) | | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | | 著者 | Yokoyama, T, Shigematsu, H, Shirouzu, M, Imataka, H, Ito, T. | | 登録日 | 2018-11-02 | | 公開日 | 2019-05-29 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (4.5 Å) | | 主引用文献 | HCV IRES Captures an Actively Translating 80S Ribosome.
Mol.Cell, 74, 2019
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7L6G
 | | MbnP from Methylosinus trichosporium | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, COPPER (II) ION, ... | | 著者 | Manesis, A.C, Rosenzweig, A.C. | | 登録日 | 2020-12-23 | | 公開日 | 2021-05-26 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | | 主引用文献 | Copper binding by a unique family of metalloproteins is dependent on kynurenine formation.
Proc.Natl.Acad.Sci.USA, 118, 2021
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6N9E
 | | Crystal structure of the Thermus thermophilus 70S ribosome in complex with a short substrate mimic CC-Pmn and bound to mRNA and P-site tRNA at 3.7A resolution | | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S19, ... | | 著者 | Melnikov, S.V, Khabibullina, N.F, Mairhofer, E, Vargas-Rodriguez, O, Reynolds, N.M, Micura, R, Soll, D, Polikanov, Y.S. | | 登録日 | 2018-12-03 | | 公開日 | 2018-12-12 | | 最終更新日 | 2025-03-19 | | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | | 主引用文献 | Mechanistic insights into the slow peptide bond formation with D-amino acids in the ribosomal active site.
Nucleic Acids Res., 47, 2019
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6ULN
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6N9F
 | | Crystal structure of the Thermus thermophilus 70S ribosome in complex with a short substrate mimic ACCA-DPhe and bound to mRNA and P-site tRNA at 3.7A resolution | | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S19, ... | | 著者 | Melnikov, S.V, Khabibullina, N.F, Mairhofer, E, Vargas-Rodriguez, O, Reynolds, N.M, Micura, R, Soll, D, Polikanov, Y.S. | | 登録日 | 2018-12-03 | | 公開日 | 2018-12-12 | | 最終更新日 | 2025-03-19 | | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | | 主引用文献 | Mechanistic insights into the slow peptide bond formation with D-amino acids in the ribosomal active site.
Nucleic Acids Res., 47, 2019
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8Q87
 | | Structure of the G. gallus 80S rotated ribosome in complex with eEF2 and SERBP1 | | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... | | 著者 | Nurullina, L, Jenner, L, Yusupov, M. | | 登録日 | 2023-08-18 | | 公開日 | 2024-08-28 | | 最終更新日 | 2025-03-12 | | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | | 主引用文献 | Cryo-EM structure of the inactive ribosome complex accumulated in chick embryo cells in cold-stress conditions.
Febs Lett., 598, 2024
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8Q7Z
 | | Structure of the G. gallus 80S non-rotated ribosome | | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... | | 著者 | Nurullina, L, Jenner, L, Yusupov, M. | | 登録日 | 2023-08-17 | | 公開日 | 2024-08-28 | | 最終更新日 | 2025-03-12 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | Cryo-EM structure of the inactive ribosome complex accumulated in chick embryo cells in cold-stress conditions.
Febs Lett., 598, 2024
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8AC2
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8AC1
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8K82
 | | Cryo-EM structure of the yeast 80S ribosome with tigecycline, Not5 and P-site tRNA | | 分子名称: | 18S rRNA, 23S rRNA, 40S ribosomal protein S1-A, ... | | 著者 | Buschauer, R, Beckmann, R, Cheng, J. | | 登録日 | 2023-07-28 | | 公開日 | 2024-07-10 | | 最終更新日 | 2024-11-06 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline.
Nat Commun, 15, 2024
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6NSH
 | | Modified ASL proline bound to Thermus thermophilus 70S (near-cognate) | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | 著者 | Hoffer, E.D, Maehigashi, T, Subaramanian, S, Hong, S, Dunham, C.M. | | 登録日 | 2019-01-24 | | 公開日 | 2020-10-14 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.397 Å) | | 主引用文献 | Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon-anticodon pairing.
Elife, 9, 2020
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6O3M
 | | Unmodified tRNA(Pro) bound to Thermus thermophilus 70S (cognate) | | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | | 著者 | Hoffer, E.D, Subaramanian, S, Hong, S, Maehigashi, T, Dunham, C.M. | | 登録日 | 2019-02-26 | | 公開日 | 2020-10-14 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (3.97 Å) | | 主引用文献 | Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon-anticodon pairing.
Elife, 9, 2020
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