6LU8
 
 | | Cryo-EM structure of a human pre-60S ribosomal subunit - state A | | 分子名称: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | | 著者 | Liang, X, Zuo, M, Zhang, Y, Li, N, Ma, C, Dong, M, Gao, N. | | 登録日 | 2020-01-26 | | 公開日 | 2020-08-26 | | 実験手法 | ELECTRON MICROSCOPY (3.13 Å) | | 主引用文献 | Structural snapshots of human pre-60S ribosomal particles before and after nuclear export.
Nat Commun, 11, 2020
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8CH6
 | | Structure of a late-stage activated spliceosome (BAqr) arrested with a dominant-negative Aquarius mutant (state B complex). | | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... | | 著者 | Cretu, C, Schmitzova, J, Pena, V. | | 登録日 | 2023-02-07 | | 公開日 | 2023-05-10 | | 最終更新日 | 2023-06-14 | | 実験手法 | ELECTRON MICROSCOPY (5.9 Å) | | 主引用文献 | Structural basis of catalytic activation in human splicing.
Nature, 617, 2023
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8C4P
 | | CdaA-compound 7 complex | | 分子名称: | CHLORIDE ION, Diadenylate cyclase, ~{N}-[5-(2-azanyl-1,3-thiazol-4-yl)-4-methyl-1,3-thiazol-2-yl]ethanamide | | 著者 | Neumann, P, Ficner, R. | | 登録日 | 2023-01-04 | | 公開日 | 2023-06-07 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | Computer-aided design of a cyclic di-AMP synthesizing enzyme CdaA inhibitor.
Microlife, 4, 2023
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8CBS
 | | HIV-1 Integrase Catalytic Core Domain and C-Terminal Domain in Complex with Allosteric Integrase Inhibitor MUT871 | | 分子名称: | (2~{S})-2-[3-cyclopropyl-6-methyl-2-(5-methyl-3,4-dihydro-2~{H}-chromen-6-yl)phenyl]-2-[(2-methylpropan-2-yl)oxy]ethanoic acid, 1,2-ETHANEDIOL, CHLORIDE ION, ... | | 著者 | Singer, M.R, Pye, V.E, Yu, Z, Cherepanov, P. | | 登録日 | 2023-01-25 | | 公開日 | 2023-06-07 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Biological and Structural Analyses of New Potent Allosteric Inhibitors of HIV-1 Integrase.
Antimicrob.Agents Chemother., 67, 2023
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1ING
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3VRF
 | | The crystal structure of hemoglobin from woolly mammoth in the carbonmonoxy forms | | 分子名称: | CARBON MONOXIDE, Hemoglobin subunit alpha, Hemoglobin subunit beta/delta hybrid, ... | | 著者 | Noguchi, H, Campbell, K.L, Ho, C, Park, S.-Y, Tame, J.R.H. | | 登録日 | 2012-04-09 | | 公開日 | 2012-11-07 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Structures of haemoglobin from woolly mammoth in liganded and unliganded states.
Acta Crystallogr.,Sect.D, 68, 2012
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2ZQJ
 | | Substrate-Free Form of Cytochrome P450BSbeta | | 分子名称: | Cytochrome P450 152A1, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Shoji, O, Fujishiro, T, Nagano, S, Hirose, T, Shiro, Y, Watanabe, Y. | | 登録日 | 2008-08-11 | | 公開日 | 2009-09-01 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Understanding substrate misrecognition of hydrogen peroxide dependent cytochrome P450 from Bacillus subtilis.
J.Biol.Inorg.Chem., 2010
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2Z7B
 | | Crystal Structure of Mesorhizobium loti 3-hydroxy-2-methylpyridine-4,5-dicarboxylate decarboxylase | | 分子名称: | MANGANESE (II) ION, Mlr6791 protein | | 著者 | McCulloch, K.M, Mukherjee, T, Ealick, S.E, Begley, T.P. | | 登録日 | 2007-08-17 | | 公開日 | 2007-11-13 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Gene Identification and Structural Characterization of the Pyridoxal 5'-Phosphate Degradative Protein 3-Hydroxy-2-methylpyridine-4,5-dicarboxylate Decarboxylase from Mesorhizobium loti MAFF303099
Biochemistry, 46, 2007
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3VX0
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6EK5
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6ONN
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6ROC
 | | Crystal structure of Borrelia burgdorferi outer surface protein BBA69, mutant Leu214Met (Se-Met data) | | 分子名称: | Putative surface protein | | 著者 | Brangulis, K, Akopjana, I, Petrovskis, I, Kazaks, A, Tars, K. | | 登録日 | 2019-05-11 | | 公開日 | 2019-06-26 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal structure of Borrelia burgdorferi outer surface protein BBA69 in comparison to the paralogous protein CspA.
Ticks Tick Borne Dis, 10, 2019
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6LQM
 | | Cryo-EM structure of a pre-60S ribosomal subunit - state C | | 分子名称: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | | 著者 | Liang, X, Zuo, M, Zhang, Y, Li, N, Ma, C, Dong, M, Gao, N. | | 登録日 | 2020-01-14 | | 公開日 | 2020-08-26 | | 実験手法 | ELECTRON MICROSCOPY (3.09 Å) | | 主引用文献 | Structural snapshots of human pre-60S ribosomal particles before and after nuclear export.
Nat Commun, 11, 2020
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1X1X
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6XN8
 | | Crystal Structure of 2-hydroxyacyl CoA lyase (HACL) from Rhodospirillales bacterium URHD0017 | | 分子名称: | 2-hydroxyacyl-CoA lyase 1, 2-{3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-4-METHYL-2-OXO-2,3-DIHYDRO-1,3-THIAZOL-5-YL}ETHYL TRIHYDROGEN DIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ... | | 著者 | Miller, M.D, Xu, W, Olmos Jr, J.L, Chou, A, Clomburg, J.M, Gonzalez, R, Philips Jr, G.N. | | 登録日 | 2020-07-02 | | 公開日 | 2021-07-07 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Crystal Structure of 2-hydroxyacyl CoA lyase (HACL) from Rhodospirillales bacterium URHD0017
To Be Published
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7P5R
 | | Racemic protein crystal structure of lacticin Q from Lactococcus lactis | | 分子名称: | D-Lacticin Q, FORMIC ACID, Lacticin Q | | 著者 | Lander, A.J, Li, X, Baumann, P, Rizkallah, P, Luk, L.Y.P, Jin, Y. | | 登録日 | 2021-07-14 | | 公開日 | 2022-07-27 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (0.96 Å) | | 主引用文献 | Roles of inter- and intramolecular tryptophan interactions in membrane-active proteins revealed by racemic protein crystallography.
Commun Chem, 6, 2023
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8SVZ
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344D
 | | DETERMINATION BY MAD-DM OF THE STRUCTURE OF THE DNA DUPLEX D(ACGTACG(5-BRU))2 AT 1.46A AND 100K | | 分子名称: | DNA (5'-D(*AP*CP*GP*TP*AP*CP*GP*(BRU))-3') | | 著者 | Todd, A.R, Adams, A, Powell, H.R, Cardin, C.J. | | 登録日 | 1997-08-04 | | 公開日 | 1997-09-26 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | | 主引用文献 | Determination by MAD-DM of the structure of the DNA duplex d[ACGTACG(5-BrU)]2 at 1.46 A and 100 K.
Acta Crystallogr.,Sect.D, 55, 1999
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1AV2
 | | Gramicidin A/CsCl complex, active as a dimer | | 分子名称: | CESIUM ION, CHLORIDE ION, GRAMICIDIN A, ... | | 著者 | Burkhart, B.M, Li, N, Langs, D.A, Duax, W.L. | | 登録日 | 1997-09-23 | | 公開日 | 1998-07-01 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | The Conducting Form of Gramicidin a is a Right-Handed Double-Stranded Double Helix.
Proc.Natl.Acad.Sci.USA, 95, 1998
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6EKQ
 | | Crystal structure of the human BRPF1 bromodomain complexed with BZ054 in space group C2 | | 分子名称: | NITRATE ION, Peregrin, ~{N}-[4-[[(3~{S},5~{R})-3,5-dimethylpiperidin-1-yl]methyl]-1,3-thiazol-2-yl]-2,4-dimethyl-1,3-oxazole-5-carboxamide | | 著者 | Zhu, J, Caflisch, A. | | 登録日 | 2017-09-26 | | 公開日 | 2018-06-27 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Structure-based discovery of selective BRPF1 bromodomain inhibitors.
Eur J Med Chem, 155, 2018
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8P7A
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8TUP
 | | Cryo-EM structure of the human MRS2 magnesium channel under Mg2+-free condition | | 分子名称: | MAGNESIUM ION, Magnesium transporter MRS2 homolog, mitochondrial | | 著者 | Lai, L.T.F, Balaraman, J, Zhou, F, Matthies, D. | | 登録日 | 2023-08-16 | | 公開日 | 2023-09-13 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Cryo-EM structures of human magnesium channel MRS2 reveal gating and regulatory mechanisms.
Nat Commun, 14, 2023
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4WUN
 | | Structure of FGFR1 in complex with AZD4547 (N-{3-[2-(3,5-DIMETHOXYPHENYL)ETHYL]-1H-PYRAZOL-5-YL}-4-[(3R,5S)-3,5-DIMETHYLPIPERAZIN-1-YL]BENZAMIDE) at 1.65 angstrom | | 分子名称: | Fibroblast growth factor receptor 1, N-{3-[2-(3,5-dimethoxyphenyl)ethyl]-1H-pyrazol-5-yl}-4-[(3R,5S)-3,5-dimethylpiperazin-1-yl]benzamide | | 著者 | Squire, C.J, Yosaatmadja, C.J. | | 登録日 | 2014-11-02 | | 公開日 | 2014-11-19 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | The 1.65 angstrom resolution structure of the complex of AZD4547 with the kinase domain of FGFR1 displays exquisite molecular recognition.
Acta Crystallogr.,Sect.D, 71, 2015
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8TUL
 | | Cryo-EM structure of the human MRS2 magnesium channel under Mg2+ condition | | 分子名称: | MAGNESIUM ION, Magnesium transporter MRS2 homolog, mitochondrial | | 著者 | Lai, L.T.F, Balaraman, J, Zhou, F, Matthies, D. | | 登録日 | 2023-08-16 | | 公開日 | 2023-09-13 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Cryo-EM structures of human magnesium channel MRS2 reveal gating and regulatory mechanisms.
Nat Commun, 14, 2023
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6ONA
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