1ING

INFLUENZA A SUBTYPE N2 NEURAMINIDASE COMPLEXED WITH AROMATIC BANA109 INHIBITOR

Summary for 1ING

• Entry DOI: 10.2210/pdb1ing/pdb
• Descriptor: INFLUENZA A SUBTYPE N2 NEURAMINIDASE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• Functional Keywords: neuraminidase, sialidase, hydrolase, o-glycosyl, hydrolase (o-glycosyl)
• Biological source: Influenza A virus
• Cellular location: Virion membrane (By similarity): P06820
• Total number of polymer chains: 2
• Total formula weight: 92175.52

Authors

Jedrzejas, M.J.,Luo, M. (deposition date: 1995-07-07, release date: 1996-08-17, Last modification date: 2020-07-29)

• Primary citation: Singh, S.,Jedrzejas, M.J.,Air, G.M.,Luo, M.,Laver, W.G.,Brouillette, W.J.; Structure-based inhibitors of influenza virus sialidase. A benzoic acid lead with novel interaction.; J.Med.Chem., 38:3217-3225, 1995; PubMed: 7650674; DOI: 10.1021/jm00017a005

Experimental method

X-RAY DIFFRACTION (2.4 Å)