PDB: 45953 件ウェブページステータス検索Chemie searchBIRD

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7M4I	DNA Polymerase Lambda, dCTP:At Mn2+ Product State Ternary Complex, 420 min 分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*CP*AP*GP*TP*AP*CP*C)-3'), DNA (5'-D(*CP*GP*GP*CP*AP*GP*TP*AP*CP*TP*G)-3'), ... 著者 Jamsen, J.A, Wilson, S.H. 登録日 2021-03-21 公開日 2022-07-06 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.005 Å) 主引用文献 Watching right and wrong nucleotide insertion captures hidden polymerase fidelity checkpoints. Nat Commun, 13, 2022
7M4D	DNA Polymerase Lambda, dCTP:At Ca2+ Ground State Ternary Complex 分子名称: 1,2-ETHANEDIOL, 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, CALCIUM ION, ... 著者 Jamsen, J.A, Wilson, S.H. 登録日 2021-03-21 公開日 2022-07-06 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.817 Å) 主引用文献 Watching right and wrong nucleotide insertion captures hidden polymerase fidelity checkpoints. Nat Commun, 13, 2022
7M48	DNA Polymerase Lambda, TTP:At Mg2+ Product State Ternary Complex, 960 min 分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*CP*AP*GP*TP*AP*CP*T)-3'), DNA (5'-D(*CP*GP*GP*CP*AP*GP*TP*AP*CP*TP*G)-3'), ... 著者 Jamsen, J.A, Wilson, S.H. 登録日 2021-03-21 公開日 2022-07-06 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Watching right and wrong nucleotide insertion captures hidden polymerase fidelity checkpoints. Nat Commun, 13, 2022
7M4L	DNA Polymerase Lambda, TTPaS:At Mn2+ Product State Ternary Complex, 60 min 分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*CP*AP*GP*TP*AP*CP*(YQS))-3'), DNA (5'-D(*CP*GP*GP*CP*AP*GP*TP*AP*CP*TP*G)-3'), ... 著者 Jamsen, J.A, Wilson, S.H. 登録日 2021-03-21 公開日 2022-07-06 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.701 Å) 主引用文献 Watching right and wrong nucleotide insertion captures hidden polymerase fidelity checkpoints. Nat Commun, 13, 2022
5E6C	Glucocorticoid receptor DNA binding domain - CCL2 NF-kB response element complex 分子名称: DNA (5'-D(*AP*GP*TP*GP*GP*AP*AP*AP*TP*TP*CP*CP*CP*AP*CP*T)-3'), DNA (5'-D(*AP*GP*TP*GP*GP*GP*AP*AP*TP*TP*TP*CP*CP*AP*CP*T)-3'), Glucocorticoid receptor, ... 著者 Hudson, W.H, Rye, E.A, Herbst, A.G, Ortlund, E.A. 登録日 2015-10-09 公開日 2017-02-08 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Cryptic glucocorticoid receptor-binding sites pervade genomic NF-kappa B response elements. Nat Commun, 9, 2018
2FQZ	Metal-depleted Ecl18kI in complex with uncleaved DNA 分子名称: DNA STRAND 1, DNA STRAND 2, R.Ecl18kI 著者 Bochtler, M, Szczepanowski, R.H, Tamulaitis, G, Grazulis, S, Czapinska, H, Manakova, E, Siksnys, V. 登録日 2006-01-18 公開日 2006-06-20 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Nucleotide flips determine the specificity of the Ecl18kI restriction endonuclease Embo J., 25, 2006
8HML	Co-crystal structure of the C terminal DNA binding domain of Saccharopolyspora erythraea GlnR in complex with its conserved promoter DNA in 2.95 Angstrom resolution 分子名称: DNA (5'-D(*AP*CP*GP*TP*AP*AP*CP*AP*TP*CP*GP*CP*GP*GP*TP*AP*AP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*TP*TP*AP*CP*CP*GP*CP*GP*AP*TP*GP*TP*TP*AP*CP*GP*T)-3'), DNA-binding response OmpR family regulator 著者 Lin, W, Xu, J.C. 登録日 2022-12-04 公開日 2023-06-07 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Structural insights into the transcription activation mechanism of the global regulator GlnR from actinobacteria. Proc.Natl.Acad.Sci.USA, 120, 2023
6WQU	CSL (RBPJ) bound to Notch3 RAM and DNA 分子名称: DNA (5'-D(*AP*AP*TP*CP*TP*TP*TP*CP*CP*CP*AP*CP*GP*GP*T)-3'), DNA (5'-D(*TP*TP*AP*CP*CP*GP*TP*GP*GP*GP*AP*AP*AP*GP*A)-3'), Neurogenic locus notch homolog protein 3, ... 著者 Kovall, R.A, Gagliani, E, Hall, D. 登録日 2020-04-29 公開日 2021-03-31 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.41 Å) 主引用文献 PIM-induced phosphorylation of Notch3 promotes breast cancer tumorigenicity in a CSL-independent fashion. J.Biol.Chem., 296, 2021
7RSS	Kod-RI incorporating DNA, n+2 分子名称: DNA polymerase, Primer, Template 著者 Hajjar, M, Chim, N, Chaput, J.C. 登録日 2021-08-11 公開日 2022-08-24 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.71 Å) 主引用文献 Crystallographic analysis of engineered polymerases synthesizing phosphonomethylthreosyl nucleic acid. Nucleic Acids Res., 50, 2022
3L1P	POU protein:DNA complex 分子名称: DNA (5'-D(*AP*TP*CP*CP*AP*TP*TP*TP*GP*CP*CP*TP*TP*TP*CP*AP*AP*AP*TP*GP*TP*GP*G)-3'), DNA (5'-D(*TP*CP*CP*AP*CP*AP*TP*TP*TP*GP*AP*AP*AP*GP*GP*CP*AP*AP*AP*TP*GP*GP*A)-3'), POU domain, ... 著者 Vahokoski, J, Groves, M.R, Pogenberg, V, Wilmanns, M. 登録日 2009-12-14 公開日 2010-12-15 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 A unique Oct4 interface is crucial for reprogramming to pluripotency Nat.Cell Biol., 15, 2013
3TWH	Selenium Derivatized RNA/DNA Hybrid in complex with RNase H Catalytic Domain D132N Mutant 分子名称: DNA (5'-D(*AP*TP*(SDG)P*TP*CP*(SDG))-3'), MAGNESIUM ION, PHOSPHATE ION, ... 著者 Rob, A, Gerlits, O, Jiang, J.S, Gan, J.H, Huang, Z. 登録日 2011-09-21 公開日 2012-10-03 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.79 Å) 主引用文献 Novel complex MAD phasing and RNase H structural insights using selenium oligonucleotides. Acta Crystallogr.,Sect.D, 70, 2014
7CSM	Crystal structure of Sulfurisphaera tokodaii O6-methylguanine methyltransferase C120S variant 分子名称: Methylated-DNA--protein-cysteine methyltransferase, SULFATE ION 著者 Kikuchi, M, Yamauchi, T, Iizuka, Y, Tsunoda, M. 登録日 2020-08-15 公開日 2021-08-18 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Roles of the hydroxy group of tyrosine in crystal structures of Sulfurisphaera tokodaii O6-methylguanine-DNA methyltransferase. Acta Crystallogr.,Sect.F, 77, 2021
6DKS	Structure of the Rbpj-SHARP-DNA Repressor Complex 分子名称: DNA (5'-D(*AP*AP*TP*CP*TP*TP*TP*CP*CP*CP*AP*CP*AP*GP*T)-3'), DNA (5'-D(*TP*TP*AP*CP*TP*GP*TP*GP*GP*GP*AP*AP*AP*GP*A)-3'), Maltose/maltodextrin-binding periplasmic protein, ... 著者 Kovall, R.A, VanderWielen, B.D, Yuan, Z. 登録日 2018-05-30 公開日 2019-01-02 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.78 Å) 主引用文献 Structural and Functional Studies of the RBPJ-SHARP Complex Reveal a Conserved Corepressor Binding Site. Cell Rep, 26, 2019
4UBC	DNA polymerase beta substrate complex with a templating cytosine and incoming 8-oxodGTP, 0 s 分子名称: 5'-D(*CP*CP*GP*AP*CP*CP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3', 5'-D(P*GP*TP*CP*GP*G)-3', ... 著者 Freudenthal, B.D, Wilson, S.H, Beard, W.A. 登録日 2014-08-12 公開日 2014-11-12 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Uncovering the polymerase-induced cytotoxicity of an oxidized nucleotide. Nature, 517, 2015
4UAZ	DNA polymerase beta reactant complex with a templating adenine and incoming 8-oxodGTP, 20 s 分子名称: 5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*CP*(8OG))-3', 5'-D(P*GP*TP*CP*GP*G)-3', ... 著者 Freudenthal, B.D, Wilson, S.H, Beard, W.A. 登録日 2014-08-11 公開日 2014-11-12 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.88 Å) 主引用文献 Uncovering the polymerase-induced cytotoxicity of an oxidized nucleotide. Nature, 517, 2015
4UB3	DNA polymerase beta closed product complex with a templating cytosine and 8-oxodGMP, 60 s 分子名称: 5'-D(*CP*CP*GP*AP*CP*CP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*CP*(8OG))-3', 5'-D(P*GP*TP*CP*GP*G)-3', ... 著者 Freudenthal, B.D, Wilson, S.H, Beard, W.A. 登録日 2014-08-11 公開日 2014-11-12 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 Uncovering the polymerase-induced cytotoxicity of an oxidized nucleotide. Nature, 517, 2015
4UBB	DNA polymerase beta reactant complex with a templating cytosine and incoming 8-oxodGTP, 40 s 分子名称: 5'-D(*CP*CP*GP*AP*CP*CP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*CP*(8OG))-3', 5'-D(P*GP*TP*CP*GP*G)-3', ... 著者 Freudenthal, B.D, Wilson, S.H, Beard, W.A. 登録日 2014-08-12 公開日 2014-11-12 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Uncovering the polymerase-induced cytotoxicity of an oxidized nucleotide. Nature, 517, 2015
4UAY	DNA polymerase beta product complex with a templating adenine and inserted 8-oxodGMP, 40 s 分子名称: 5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*CP*(8OG))-3', 5'-D(P*GP*TP*CP*GP*G)-3', ... 著者 Freudenthal, B.D, Wilson, S.H, Beard, W.A. 登録日 2014-08-11 公開日 2014-11-12 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.984 Å) 主引用文献 Uncovering the polymerase-induced cytotoxicity of an oxidized nucleotide. Nature, 517, 2015
3LHQ	DNA-binding transcriptional repressor AcrR from Salmonella typhimurium. 分子名称: 1,2-ETHANEDIOL, AcrAB operon repressor (TetR/AcrR family), DI(HYDROXYETHYL)ETHER 著者 Osipiuk, J, Mulligan, R, Papazisi, L, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2010-01-22 公開日 2010-02-02 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.56 Å) 主引用文献 X-ray crystal structure of DNA-binding transcriptional repressor AcrR from Salmonella typhimurium. To be Published
4UAW	DNA polymerase beta substrate complex with a templating adenine and incoming 8-oxodGTP, 0 s 分子名称: 5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3', 5'-D(P*GP*TP*CP*GP*G)-3', ... 著者 Freudenthal, B.D, Wilson, S.H, Beard, W.A. 登録日 2014-08-11 公開日 2014-11-12 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Uncovering the polymerase-induced cytotoxicity of an oxidized nucleotide. Nature, 517, 2015
4UB5	DNA polymerase beta substrate complex with a templating cytosine, incoming 8-oxodGTP, and Mn2+, 5 s 分子名称: 5'-D(*CP*CP*GP*AP*CP*CP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3', 5'-D(P*GP*TP*CP*GP*G)-3', ... 著者 Freudenthal, B.D, Wilson, S.H, Beard, W.A. 登録日 2014-08-11 公開日 2014-11-12 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Uncovering the polymerase-induced cytotoxicity of an oxidized nucleotide. Nature, 517, 2015
4UB4	DNA polymerase beta substrate complex with a templating cytosine and incoming dGTP, 0 s 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 5'-D(*CP*CP*GP*AP*CP*CP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3', ... 著者 Freudenthal, B.D, Wilson, S.H, Beard, W.A. 登録日 2014-08-11 公開日 2014-11-12 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.954 Å) 主引用文献 Uncovering the polymerase-induced cytotoxicity of an oxidized nucleotide. Nature, 517, 2015
4UB2	DNA polymerase beta product complex with a templating cytosine and 8-oxodGMP, 120 s 分子名称: 5'-D(*CP*CP*GP*AP*CP*CP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*CP*(8OG))-3', 5'-D(P*GP*TP*CP*GP*G)-3', ... 著者 Freudenthal, B.D, Wilson, S.H, Beard, W.A. 登録日 2014-08-11 公開日 2014-11-12 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.51 Å) 主引用文献 Uncovering the polymerase-induced cytotoxicity of an oxidized nucleotide. Nature, 517, 2015
4UB1	DNA polymerase beta product complex with a templating adenine and 8-oxodGMP, 90 s 分子名称: 5'-D(*CP*CP*GP*AP*CP*AP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*CP*(8OG))-3', 5'-D(P*GP*TP*CP*GP*G)-3', ... 著者 Freudenthal, B.D, Wilson, S.H, Beard, W.A. 登録日 2014-08-11 公開日 2014-11-12 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.341 Å) 主引用文献 Uncovering the polymerase-induced cytotoxicity of an oxidized nucleotide. Nature, 517, 2015
1I5W	A-DNA DECAMER GCGTA(TLN)ACGC 分子名称: 5'-D(*GP*CP*GP*TP*AP*(TLN)P*AP*CP*GP*C)-3' 著者 Egli, M, Minasov, G, Teplova, M, Kumar, R, Wengel, J. 登録日 2001-03-01 公開日 2001-04-04 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 X-ray crystal structure of a locked nucleic acid (LNA) duplex composed of a palindromic 10-mer DNA strand containing one LNA thymine monomer J.Chem.Soc.,Chem.Commun., 2001

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