4UBC
DNA polymerase beta substrate complex with a templating cytosine and incoming 8-oxodGTP, 0 s
Summary for 4UBC
Entry DOI | 10.2210/pdb4ubc/pdb |
Related | 4UAW 4UAY 4UAZ 4UB1 4UB2 4UB3 4UB4 4UB5 4UBB |
Descriptor | 5'-D(*CP*CP*GP*AP*CP*CP*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', 5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*C)-3', 5'-D(P*GP*TP*CP*GP*G)-3', ... (7 entities in total) |
Functional Keywords | dna polymerase, transferase, lyase-dna complex, lyase/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 48311.26 |
Authors | Freudenthal, B.D.,Wilson, S.H.,Beard, W.A. (deposition date: 2014-08-12, release date: 2014-11-12, Last modification date: 2023-09-27) |
Primary citation | Freudenthal, B.D.,Beard, W.A.,Perera, L.,Shock, D.D.,Kim, T.,Schlick, T.,Wilson, S.H. Uncovering the polymerase-induced cytotoxicity of an oxidized nucleotide. Nature, 517:635-639, 2015 Cited by PubMed: 25409153DOI: 10.1038/nature13886 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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