7M4I

DNA Polymerase Lambda, dCTP:At Mn2+ Product State Ternary Complex, 420 min

Summary for 7M4I

• Entry DOI: 10.2210/pdb7m4i/pdb
• Descriptor: DNA polymerase lambda, DNA (5'-D(*CP*GP*GP*CP*AP*GP*TP*AP*CP*TP*G)-3'), DNA (5'-D(*CP*AP*GP*TP*AP*CP*C)-3'), ... (9 entities in total)
• Functional Keywords: time-lapse crystallography, double strand break repair, dna synthesis fidelity, replication
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 43950.37

Authors

Jamsen, J.A.,Wilson, S.H. (deposition date: 2021-03-21, release date: 2022-07-06, Last modification date: 2023-10-18)

• Primary citation: Jamsen, J.A.,Shock, D.D.,Wilson, S.H.; Watching right and wrong nucleotide insertion captures hidden polymerase fidelity checkpoints.; Nat Commun, 13:3193-3193, 2022; PubMed: 35680862; DOI: 10.1038/s41467-022-30141-w

Experimental method

X-RAY DIFFRACTION (2.005 Å)