7M4I
DNA Polymerase Lambda, dCTP:At Mn2+ Product State Ternary Complex, 420 min
Summary for 7M4I
Entry DOI | 10.2210/pdb7m4i/pdb |
Descriptor | DNA polymerase lambda, DNA (5'-D(*CP*GP*GP*CP*AP*GP*TP*AP*CP*TP*G)-3'), DNA (5'-D(*CP*AP*GP*TP*AP*CP*C)-3'), ... (9 entities in total) |
Functional Keywords | time-lapse crystallography, double strand break repair, dna synthesis fidelity, replication |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 43950.37 |
Authors | Jamsen, J.A.,Wilson, S.H. (deposition date: 2021-03-21, release date: 2022-07-06, Last modification date: 2023-10-18) |
Primary citation | Jamsen, J.A.,Shock, D.D.,Wilson, S.H. Watching right and wrong nucleotide insertion captures hidden polymerase fidelity checkpoints. Nat Commun, 13:3193-3193, 2022 Cited by PubMed: 35680862DOI: 10.1038/s41467-022-30141-w PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.005 Å) |
Structure validation
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