8TSP
 
 | | Open, inward-facing MsbA structure (OIF1) | | 分子名称: | ATP-binding transport protein MsbA | | 著者 | Yang, B, Zhang, T, Lyu, J, Laganowsky, A.D, Zhao, M. | | 登録日 | 2023-08-11 | | 公開日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Native mass spectrometry captures snapshots of the MsbA transport cycle
To Be Published
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8TSO
 | | KDL bound, nucleotide-free MsbA in open, outward-facing conformation | | 分子名称: | (2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-[(2~{R},4~{R},5~{R},6~{R})-6-[(1~{R})-1,2-bis(oxidanyl)ethyl]-2-carboxy-2-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-5-[[(3~{R})-3-dodecanoyloxytetradecanoyl]amino]-6-[[(2~{R},3~{S},4~{R},5~{R},6~{R})-3-oxidanyl-5-[[(3~{R})-3-oxidanyltetradecanoyl]amino]-4-[(3~{R})-3-oxidanyltetradecanoyl]oxy-6-phosphonooxy-oxan-2-yl]methoxy]-3-phosphonooxy-4-[(3~{R})-3-tetradecanoyloxytetradecanoyl]oxy-oxan-2-yl]methoxy]-5-oxidanyl-oxan-4-yl]oxy-4,5-bis(oxidanyl)oxane-2-carboxylic acid, ATP-binding transport protein MsbA, PENTAETHYLENE GLYCOL MONODECYL ETHER | | 著者 | Yang, B, Zhang, T, Lyu, J, Laganowsky, A.D, Zhao, M. | | 登録日 | 2023-08-11 | | 公開日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (2.68 Å) | | 主引用文献 | Native mass spectrometry captures snapshots of the MsbA transport cycle
To Be Published
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8TSQ
 | | Open, inward-facing MsbA structure (OIF2) | | 分子名称: | ATP-binding transport protein MsbA | | 著者 | Yang, B, Zhang, T, Lyu, J, Laganowsky, A.D, Zhao, M. | | 登録日 | 2023-08-11 | | 公開日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Native mass spectrometry captures snapshots of the MsbA transport cycle
To Be Published
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8TSS
 | | Open, inward-facing MsbA structure (OIF3) | | 分子名称: | ATP-binding transport protein MsbA | | 著者 | Yang, B, Zhang, T, Lyu, J, Laganowsky, A.D, Zhao, M. | | 登録日 | 2023-08-11 | | 公開日 | 2024-06-19 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Native mass spectrometry captures snapshots of the MsbA transport cycle
To Be Published
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8KDX
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8Q61
 | | Co-crystal structure of human AKT2 with compound 3 | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-[4-(1-azanyl-3-methyl-3-oxidanyl-cyclobutyl)phenyl]-7-phenyl-1-propyl-pyrido[2,3-b][1,4]oxazin-2-one, GLYCEROL, ... | | 著者 | Harrison, T, Barker, O. | | 登録日 | 2023-08-10 | | 公開日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | | 主引用文献 | Identification and development of a subtype-selective allosteric AKT inhibitor suitable for clinical development.
Sci Rep, 12, 2022
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8TS0
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8Q62
 | | Early closed conformation of the g-tubulin ring complex | | 分子名称: | Gamma-tubulin complex component 2, Gamma-tubulin complex component 3, Gamma-tubulin complex component 4, ... | | 著者 | Llorca, O, Serna, M, Fernandez-Leiro, R. | | 登録日 | 2023-08-10 | | 公開日 | 2024-02-07 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.72 Å) | | 主引用文献 | Transition of human gamma-tubulin ring complex into a closed conformation during microtubule nucleation.
Science, 383, 2024
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8TRN
 | | Actin 1 from T. gondii in filaments bound to MgADP and jasplakinolide | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, Jasplakinolide, ... | | 著者 | Hvorecny, K.L, Sladewski, T.E, Heaslip, A.T, Kollman, J.M. | | 登録日 | 2023-08-09 | | 公開日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Toxoplasma gondii actin filaments are tuned for rapid disassembly and turnover.
Nat Commun, 15, 2024
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8TRM
 | | Actin 1 from T. gondii in filaments bound to MgADP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Actin, MAGNESIUM ION | | 著者 | Hvorecny, K.L, Sladewski, T.E, Heaslip, A.T, Kollman, J.M. | | 登録日 | 2023-08-09 | | 公開日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | Toxoplasma gondii actin filaments are tuned for rapid disassembly and turnover.
Nat Commun, 15, 2024
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8Q5J
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8Q52
 | | A PBP-like protein built from fragments of different folds | | 分子名称: | Leucine-specific-binding protein,Chemotaxis protein CheY, SULFATE ION | | 著者 | Shanmugaratnam, S, Toledo-Patino, S, Goetz, S.K, Farias-Rico, J.A, Hocker, B. | | 登録日 | 2023-08-08 | | 公開日 | 2024-04-10 | | 最終更新日 | 2024-06-19 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Molecular handcraft of a well-folded protein chimera.
Febs Lett., 598, 2024
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8TQS
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8Q4G
 | | Thin filament from FIB milled relaxed left ventricular mouse myofibrils | | 分子名称: | Actin, alpha cardiac muscle 1, Tropomyosin alpha-1 chain | | 著者 | Tamborrini, D, Wang, Z, Wagner, T, Tacke, S, Stabrin, M, Grange, M, Kho, A.L, Bennet, P, Rees, M, Gautel, M, Raunser, S. | | 登録日 | 2023-08-06 | | 公開日 | 2023-11-01 | | 最終更新日 | 2023-12-06 | | 実験手法 | ELECTRON MICROSCOPY (8 Å) | | 主引用文献 | Structure of the native myosin filament in the relaxed cardiac sarcomere.
Nature, 623, 2023
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8TP1
 | | ATP-2 state of Bcs1 (C7 symmetrized) | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Mitochondrial chaperone BCS1 | | 著者 | Zhan, J, Xia, D. | | 登録日 | 2023-08-04 | | 公開日 | 2024-06-05 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.02 Å) | | 主引用文献 | Conformations of Bcs1L undergoing ATP hydrolysis suggest a concerted translocation mechanism for folded iron-sulfur protein substrate.
Nat Commun, 15, 2024
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8Q3O
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8Q3Q
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8Q3N
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8Q3P
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8TPL
 | | ATP-2 state of Bcs1 (unsymmetrized) | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Mitochondrial chaperone BCS1 | | 著者 | Zhan, J, Xia, D. | | 登録日 | 2023-08-04 | | 公開日 | 2024-06-05 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.46 Å) | | 主引用文献 | Conformations of Bcs1L undergoing ATP hydrolysis suggest a concerted translocation mechanism for folded iron-sulfur protein substrate.
Nat Commun, 15, 2024
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8Q3L
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8Q3C
 | | Structure of Selenomonas ruminantium lactate dehydrogenase I85R mutant | | 分子名称: | CHLORIDE ION, L-lactate dehydrogenase, NITRATE ION, ... | | 著者 | Bertrand, Q, Coquille, S, Iorio, A, Sterpone, F, Madern, D. | | 登録日 | 2023-08-03 | | 公開日 | 2023-11-01 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Biochemical, structural and dynamical characterizations of the lactate dehydrogenase from Selenomonas ruminantium provide information about an intermediate evolutionary step prior to complete allosteric regulation acquisition in the super family of lactate and malate dehydrogenases.
J.Struct.Biol., 215, 2023
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8TO0
 | | 48-nm repeating structure of doublets from mouse sperm flagella | | 分子名称: | Cilia- and flagella- associated protein 210, Cilia- and flagella-associated protein 107, Cilia- and flagella-associated protein 141, ... | | 著者 | Chen, Z, Shiozak, M, Hass, K.M, Skinner, W, Zhao, S, Guo, C, Polacco, B.J, Yu, Z, Krogan, N.J, Kaake, R.M, Vale, R.D, Agard, D.A. | | 登録日 | 2023-08-02 | | 公開日 | 2023-11-01 | | 最終更新日 | 2023-11-22 | | 実験手法 | ELECTRON MICROSCOPY (7.7 Å) | | 主引用文献 | De novo protein identification in mammalian sperm using in situ cryoelectron tomography and AlphaFold2 docking.
Cell, 186, 2023
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8TNK
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8TNR
 | | Cryo-EM structure of DDB1dB:CRBN:PT-179:SD40, conformation 2 | | 分子名称: | 2-[(3S)-2,6-dioxopiperidin-3-yl]-5-(morpholin-4-yl)-1H-isoindole-1,3(2H)-dione, DNA damage-binding protein 1, Maltose/maltodextrin-binding periplasmic protein,SD40, ... | | 著者 | Roy Burman, S.S, Hunkeler, M, Fischer, E.S. | | 登録日 | 2023-08-02 | | 公開日 | 2024-03-13 | | 最終更新日 | 2024-04-03 | | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | | 主引用文献 | Continuous evolution of compact protein degradation tags regulated by selective molecular glues.
Science, 383, 2024
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