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4ZVS
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Caspase-7 Variant 1 (V1) with reprogrammed substrate specificity due to Y230A/W232M/S234N substitutions, bound to DEVD inhibitor.
分子名称: Caspase-7, DEVD inhibitor
著者MacPherson, D.J, Hill, M.E, Hardy, J.A.
登録日2015-05-18
公開日2016-04-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Reprogramming Caspase-7 Specificity by Regio-Specific Mutations and Selection Provides Alternate Solutions for Substrate Recognition.
Acs Chem.Biol., 11, 2016
4ZVO
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Caspase-7 Variant 4 (V4) with reprogrammed substrate specificity due to Y230V/W232Y/S234V/Q276D substitutions bound to VEID inhibitor.
分子名称: Caspase-7, Peptide ACE-VAL-GLU-ILE-ASJ
著者Hill, M.E, MacPherson, D.J, Hardy, J.A.
登録日2015-05-18
公開日2016-04-20
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Reprogramming Caspase-7 Specificity by Regio-Specific Mutations and Selection Provides Alternate Solutions for Substrate Recognition.
Acs Chem.Biol., 11, 2016
5AB7
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Crystal structure of Trypanosoma brucei SCP2-thiolase like protein (TbSLP) in complex with malonyl-CoA.
分子名称: MALONYL-COENZYME A, SCP2-THIOLASE LIKE PROTEIN, SULFATE ION
著者Harijan, R.K, Kiema, T.R, Wierenga, R.K.
登録日2015-08-02
公開日2016-05-04
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The Scp2-Thiolase-Like Protein (Slp) of Trypanosoma Brucei is an Enzyme Involved in Lipid Metabolism.
Proteins, 84, 2016
5AB5
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Crystal structure of Trypanosoma brucei SCP2-thiolase like protein (TbSLP) form-II.
分子名称: SCP2-THIOLASE LIKE PROTEIN, SULFATE ION
著者Harijan, R.K, Kiema, T.R, Wierenga, R.K.
登録日2015-08-01
公開日2016-05-04
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Scp2-Thiolase-Like Protein (Slp) of Trypanosoma Brucei is an Enzyme Involved in Lipid Metabolism.
Proteins, 84, 2016
5AB6
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Crystal structure of Trypanosoma brucei SCP2-thiolase like protein (TbSLP) in complex with acetoacetyl-CoA.
分子名称: ACETOACETYL-COENZYME A, SCP2-THIOLASE LIKE PROTEIN, SULFATE ION
著者Harijan, R.K, Kiema, T.R, Wierenga, R.K.
登録日2015-08-01
公開日2016-05-04
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The Scp2-Thiolase-Like Protein (Slp) of Trypanosoma Brucei is an Enzyme Involved in Lipid Metabolism.
Proteins, 84, 2016
5AB4
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Crystal structure of Trypanosoma brucei SCP2-thiolase like protein (TbSLP) form-I.
分子名称: SCP2-THIOLASE LIKE PROTEIN
著者Harijan, R.K, Kiema, T.R, Wierenga, R.K.
登録日2015-08-01
公開日2016-05-04
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.751 Å)
主引用文献The Scp2-Thiolase-Like Protein (Slp) of Trypanosoma Brucei is an Enzyme Involved in Lipid Metabolism.
Proteins, 84, 2016
5JG4
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BU of 5jg4 by Molmil
Structure of the effector protein LpiR1 (Lpg0634) from Legionella pneumophila
分子名称: CITRATE ANION, GLYCEROL, PHOSPHATE ION, ...
著者Beyrakhova, K, van Straaten, K, Cygler, M.
登録日2016-04-19
公開日2016-05-04
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural and Functional Investigations of the Effector Protein LpiR1 from Legionella pneumophila.
J.Biol.Chem., 291, 2016
5FCJ
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Structure of the anisomycin-containing uL3 W255C mutant 80S yeast ribosome
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
著者Mailliot, J, Garreau de Loubresse, N, Yusupova, G, Dinman, J.D, Yusupov, M.
登録日2015-12-15
公開日2016-05-11
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal Structures of the uL3 Mutant Ribosome: Illustration of the Importance of Ribosomal Proteins for Translation Efficiency.
J.Mol.Biol., 428, 2016
5FCI
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BU of 5fci by Molmil
Structure of the vacant uL3 W255C mutant 80S yeast ribosome
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
著者Mailliot, J, Garreau de Loubresse, N, Yusupova, G, Dinman, J.D, Yusupov, M.
登録日2015-12-15
公開日2016-05-11
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Crystal Structures of the uL3 Mutant Ribosome: Illustration of the Importance of Ribosomal Proteins for Translation Efficiency.
J.Mol.Biol., 428, 2016
5C51
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Probing the Structural and Molecular Basis of Nucleotide Selectivity by Human Mitochondrial DNA Polymerase gamma
分子名称: DNA, DNA (5'-D(*(AD)P*AP*AP*AP*CP*GP*AP*GP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*GP*TP*AP*C)-3'), DNA polymerase subunit gamma-1, ...
著者Sohl, C.D, Szymanski, M.R, Mislak, A.C, Shumate, C.K, Amiralaei, S, Schinazi, R.F, Anderson, K.S, Whitney, Y.Y.
登録日2015-06-19
公開日2016-05-11
最終更新日2016-05-18
実験手法X-RAY DIFFRACTION (3.426 Å)
主引用文献Probing the structural and molecular basis of nucleotide selectivity by human mitochondrial DNA polymerase gamma.
Proc.Natl.Acad.Sci.USA, 112, 2015
5C52
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Probing the Structural and Molecular Basis of Nucleotide Selectivity by Human Mitochondrial DNA Polymerase gamma
分子名称: DNA (26-MER), DNA (5'-D(*AP*AP*AP*AP*CP*GP*AP*GP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*GP*TP*AP*C)-3'), DNA polymerase subunit gamma-1, ...
著者Sohl, C.D, Szymanski, M.R, Mislak, A.C, Shumate, C.K, Amiralaei, S, Schinazi, R.F, Anderson, K.S, Yin, Y.W.
登録日2015-06-19
公開日2016-05-11
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.637 Å)
主引用文献Probing the structural and molecular basis of nucleotide selectivity by human mitochondrial DNA polymerase gamma.
Proc.Natl.Acad.Sci.USA, 112, 2015
5IT9
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BU of 5it9 by Molmil
Structure of the yeast Kluyveromyces lactis small ribosomal subunit in complex with the cricket paralysis virus IRES.
分子名称: 18S ribosomal RNA, Cricket paralysis virus IRES RNA, MAGNESIUM ION, ...
著者Murray, J, Savva, C.G, Shin, B.S, Dever, T.E, Ramakrishnan, V, Fernandez, I.S.
登録日2016-03-16
公開日2016-05-18
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural characterization of ribosome recruitment and translocation by type IV IRES.
Elife, 5, 2016
5IT7
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BU of 5it7 by Molmil
Structure of the Kluyveromyces lactis 80S ribosome in complex with the cricket paralysis virus IRES and eEF2
分子名称: (2S)-1-amino-N,N,N-trimethyl-1-oxobutan-2-aminium, 18S ribosomal RNA, 25S ribosomal RNA, ...
著者Murray, J, Savva, C.G, Shin, B.S, Dever, T.E, Ramakrishnan, V, Fernandez, I.S.
登録日2016-03-16
公開日2016-05-18
最終更新日2018-11-21
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural characterization of ribosome recruitment and translocation by type IV IRES.
Elife, 5, 2016
5HHG
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BU of 5hhg by Molmil
Mouse importin alpha: Dengue 2 NS5 C-terminal NLS peptide complex
分子名称: Importin subunit alpha-1, RNA-directed RNA polymerase NS5
著者Smith, K.M, Forwood, J.K.
登録日2016-01-11
公開日2016-05-18
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The C-terminal 18 Amino Acid Region of Dengue Virus NS5 Regulates its Subcellular Localization and Contains a Conserved Arginine Residue Essential for Infectious Virus Production.
PLoS Pathog., 12, 2016
5FC8
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BU of 5fc8 by Molmil
Mouse importin alpha: Dengue 3 NS5 C-terminal NLS peptide complex
分子名称: Importin subunit alpha-1, Nonstructural protein 5
著者Smith, K.M, Forwood, J.K.
登録日2015-12-15
公開日2016-05-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The C-terminal 18 Amino Acid Region of Dengue Virus NS5 Regulates its Subcellular Localization and Contains a Conserved Arginine Residue Essential for Infectious Virus Production.
PLoS Pathog., 12, 2016
5DC3
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BU of 5dc3 by Molmil
Complex of yeast 80S ribosome with non-modified eIF5A
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
著者Melnikov, S, Mailliot, J, Shin, B.-S, Rigger, L, Yusupova, G, Micura, R, Dever, T.E, Yusupov, M.
登録日2015-08-23
公開日2016-06-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Crystal Structure of Hypusine-Containing Translation Factor eIF5A Bound to a Rotated Eukaryotic Ribosome.
J.Mol.Biol., 428, 2016
5I4L
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BU of 5i4l by Molmil
Crystal structure of Amicoumacin A bound to the yeast 80S ribosome
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
著者Prokhorova, I.V, Yusupova, G, Yusupov, M.
登録日2016-02-12
公開日2016-06-22
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Amicoumacin A induces cancer cell death by targeting the eukaryotic ribosome.
Sci Rep, 6, 2016
5DY6
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BU of 5dy6 by Molmil
Enhanced superfolder GFP with DBCO at 148
分子名称: Green fluorescent protein, SULFATE ION
著者Jones, D.D, Rizkallah, P.J, Worthy, H.L.
登録日2015-09-24
公開日2016-07-13
最終更新日2018-05-30
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献Molecular basis for functional switching of GFP by two disparate non-native post-translational modifications of a phenyl azide reaction handle.
Chem Sci, 7, 2016
5BT0
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BU of 5bt0 by Molmil
Switching GFP fluorescence using genetically encoded phenyl azide chemistry through two different non-native post-translational modifications routes at the same position.
分子名称: Green fluorescent protein, SULFATE ION
著者Hartley, A.M, Worthy, H.L, Reddington, S.C, Rizkallah, P.J, Jones, D.D.
登録日2015-06-02
公開日2016-07-13
最終更新日2017-05-10
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献Molecular basis for functional switching of GFP by two disparate non-native post-translational modifications of a phenyl azide reaction handle.
Chem Sci, 7, 2016
5K0Y
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BU of 5k0y by Molmil
m48S late-stage initiation complex, purified from rabbit reticulocytes lysates, displaying eIF2 ternary complex and eIF3 i and g subunits relocated to the intersubunit face
分子名称: 18S ribosomal RNA, 40S ribosomal protein S12, 40S ribosomal protein S21, ...
著者Simonetti, A, Brito Querido, J, Myasnikov, A.G, Mancera-Martinez, E, Renaud, A, Kuhn, L, Hashem, Y.
登録日2016-05-17
公開日2016-07-13
最終更新日2018-04-18
実験手法ELECTRON MICROSCOPY (5.8 Å)
主引用文献eIF3 Peripheral Subunits Rearrangement after mRNA Binding and Start-Codon Recognition.
Mol.Cell, 63, 2016
5BTT
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BU of 5btt by Molmil
Switching GFP fluorescence using genetically encoded phenyl azide chemistry through two different non-native post-translational modifications routes at the same position.
分子名称: GLYCEROL, Green fluorescent protein, SULFATE ION
著者Hartley, A.M, Worthy, H.L, Reddington, S.C, Rizkallah, P.J, Jones, D.D.
登録日2015-06-03
公開日2016-07-13
最終更新日2017-05-10
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Molecular basis for functional switching of GFP by two disparate non-native post-translational modifications of a phenyl azide reaction handle.
Chem Sci, 7, 2016
5JPQ
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BU of 5jpq by Molmil
Cryo-EM structure of the 90S pre-ribosome
分子名称: 18S ribosomal RNA, Bms1, Emg1, ...
著者Turk, M, Cheng, J, Berninghausen, O, Kornprobst, M, Flemming, D, Kos-Braun, I.C, Kos, M, Thoms, M, Hurt, E, Beckmann, R.
登録日2016-05-04
公開日2016-07-27
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (7.3 Å)
主引用文献Architecture of the 90S Pre-ribosome: A Structural View on the Birth of the Eukaryotic Ribosome.
Cell, 166, 2016
5KTG
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BU of 5ktg by Molmil
Crystal structure of mouse Bak BH3-in-groove homodimer (GFP)
分子名称: Green fluorescent protein, Bcl-2 homologous antagonist/killer
著者Mandal, T, Choe, J.-Y, Oh, K.J.
登録日2016-07-11
公開日2016-08-17
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.802 Å)
主引用文献Assembly of Bak homodimers into higher order homooligomers in the mitochondrial apoptotic pore.
Sci Rep, 6, 2016
5DAT
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BU of 5dat by Molmil
Complex of yeast 80S ribosome with hypusine-containing eIF5A
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
著者Melnikov, S, Mailliot, J, Shin, B.-S, Rigger, L, Yusupova, G, Micura, R, Dever, T.E, Yusupov, M.
登録日2015-08-20
公開日2016-08-31
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome
To Be Published
5EG1
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Antibacterial peptide ABC transporter McjD with a resolved lipid
分子名称: (2S)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(6E)-HEXADEC-6-ENOYLOXY]PROPYL (8E)-OCTADEC-8-ENOATE, MAGNESIUM ION, Microcin-J25 export ATP-binding/permease protein McjD, ...
著者Choudhury, H.G, Beis, K.
登録日2015-10-26
公開日2016-08-31
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.42 Å)
主引用文献Structural and Functional Basis for Lipid Synergy on the Activity of the Antibacterial Peptide ABC Transporter McjD.
J.Biol.Chem., 291, 2016

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