6KW3
 
 | | The ClassA RSC-Nucleosome Complex | | 分子名称: | Actin-like protein ARP9, Actin-related protein 7, Chromatin structure-remodeling complex protein RSC3, ... | | 著者 | Ye, Y.P, Wu, H, Chen, K.J, Verma, N, Cairns, B, Gao, N, Chen, Z.C. | | 登録日 | 2019-09-05 | | 公開日 | 2019-11-13 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (7.13 Å) | | 主引用文献 | Structure of the RSC complex bound to the nucleosome.
Science, 366, 2019
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7WBV
 | | RNA polymerase II elongation complex bound with Elf1 and Spt4/5, stalled at SHL(-4) of the nucleosome | | 分子名称: | DNA (159-MER), DNA (198-MER), DNA-directed RNA polymerase subunit, ... | | 著者 | Osumi, K, Kujirai, T, Ehara, H, Sekine, S, Takizawa, Y, Kurumizaka, H. | | 登録日 | 2021-12-17 | | 公開日 | 2023-07-05 | | 最終更新日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Structural Basis of Damaged Nucleotide Recognition by Transcribing RNA Polymerase II in the Nucleosome.
J.Mol.Biol., 435, 2023
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7WBX
 | | RNA polymerase II elongation complex bound with Elf1 and Spt4/5, stalled at SHL(-3) of the nucleosome | | 分子名称: | DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Osumi, K, Kujirai, T, Ehara, H, Sekine, S, Takizawa, Y, Kurumizaka, H. | | 登録日 | 2021-12-17 | | 公開日 | 2023-07-05 | | 最終更新日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Structural Basis of Damaged Nucleotide Recognition by Transcribing RNA Polymerase II in the Nucleosome.
J.Mol.Biol., 435, 2023
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7WBW
 | | RNA polymerase II elongation complex bound with Elf1 and Spt4/5, stalled at SHL(-3.5) of the nucleosome | | 分子名称: | DNA (198-MER), DNA-directed RNA polymerase subunit, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Osumi, K, Kujirai, T, Ehara, H, Sekine, S, Takizawa, Y, Kurumizaka, H. | | 登録日 | 2021-12-17 | | 公開日 | 2023-07-05 | | 最終更新日 | 2024-06-26 | | 実験手法 | ELECTRON MICROSCOPY (7.1 Å) | | 主引用文献 | Structural Basis of Damaged Nucleotide Recognition by Transcribing RNA Polymerase II in the Nucleosome.
J.Mol.Biol., 435, 2023
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6KSW
 | | Cryo-EM structure of the human concentrative nucleoside transporter CNT3 | | 分子名称: | Solute carrier family 28 member 3 | | 著者 | Zhou, Y.X, Liao, L.H, Li, J.L, Xiao, Q.J, Sun, L.F, Deng, D. | | 登録日 | 2019-08-26 | | 公開日 | 2020-08-26 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Cryo-EM structure of the human concentrative nucleoside transporter CNT3.
Plos Biol., 18, 2020
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7U0G
 | | structure of LIN28b nucleosome bound 3 OCT4 | | 分子名称: | DNA (162-MER), Histone H2A type 2-C, Histone H2B type 2-E, ... | | 著者 | Lian, T, Guan, R, Bai, Y. | | 登録日 | 2022-02-18 | | 公開日 | 2023-06-28 | | 最終更新日 | 2024-11-06 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Structural mechanism of LIN28B nucleosome targeting by OCT4.
Mol.Cell, 83, 2023
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7U0J
 | | Structure of 162bp LIN28b nucleosome | | 分子名称: | DNA (162-MER), Histone H2A type 2-C, Histone H2B type 2-E, ... | | 著者 | Lian, T, Guan, R, Bai, Y. | | 登録日 | 2022-02-18 | | 公開日 | 2023-06-28 | | 最終更新日 | 2024-11-06 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Structural mechanism of LIN28B nucleosome targeting by OCT4.
Mol.Cell, 83, 2023
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7U0I
 | | Structure of LIN28b nucleosome bound 2 OCT4 | | 分子名称: | DNA (162-MER), Histone H2A type 2-C, Histone H2B type 2-E, ... | | 著者 | Tengfei, L, Guan, R, Bai, Y. | | 登録日 | 2022-02-18 | | 公開日 | 2023-06-28 | | 最終更新日 | 2024-11-06 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Structural mechanism of LIN28B nucleosome targeting by OCT4.
Mol.Cell, 83, 2023
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3HVT
 | | STRUCTURAL BASIS OF ASYMMETRY IN THE HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 REVERSE TRANSCRIPTASE HETERODIMER | | 分子名称: | 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, HIV-1 REVERSE TRANSCRIPTASE (SUBUNIT P51), HIV-1 REVERSE TRANSCRIPTASE (SUBUNIT P66) | | 著者 | Steitz, T.A, Smerdon, S.J, Jaeger, J, Wang, J, Kohlstaedt, L.A, Chirino, A.J, Friedman, J.M, Rice, P.A. | | 登録日 | 1994-07-25 | | 公開日 | 1994-10-15 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structure of the binding site for nonnucleoside inhibitors of the reverse transcriptase of human immunodeficiency virus type 1.
Proc.Natl.Acad.Sci.Usa, 91, 1994
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6LA8
 | | 349 bp di-nucleosome harboring cohesive DNA termini assembled with linker histone H1.0 | | 分子名称: | CALCIUM ION, DNA (349-MER), Histone H1.0, ... | | 著者 | Adhireksan, Z, Lee, P.L, Sharma, D, Davey, C.A. | | 登録日 | 2019-11-12 | | 公開日 | 2020-10-07 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Near-atomic resolution structures of interdigitated nucleosome fibres.
Nat Commun, 11, 2020
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4WR2
 | | Crystal structure of a putative pyrimidine-specific ribonucleoside hydrolase (RihA) Protein from Shewanella loihica PV-4 (SHEW_0697, Target PSI-029635) with divalent cation and PEG 400 bound at the active site | | 分子名称: | CALCIUM ION, PENTAETHYLENE GLYCOL, Pyrimidine-specific ribonucleoside hydrolase RihA | | 著者 | Himmel, D.M, Bhosle, R, Toro, R, Hillerich, B, Gizzi, A, Garforth, S, Kar, A, Chan, M.K, Lafluer, J, Patel, H, Matikainen, B, Chamala, S, Lim, S, Celikgil, A, Villegas, G, Evans, B, Love, J, Fiser, A, Seidel, R.D, Bonanno, J.B, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | | 登録日 | 2014-10-22 | | 公開日 | 2014-11-12 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Crystal structure of a putative pyrimidine-specific ribonucleoside hydrolase (RihA) Protein from Shewanella loihica PV-4 (SHEW_0697, Target PSI-029635) with divalent cation and PEG 400 bound at the active site
To be published
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8HR1
 | | Cryo-EM structure of SSX1 bound to the unmodified nucleosome at a resolution of 3.02 angstrom | | 分子名称: | DNA (147-MER), Histone H2A type 1-B/E, Histone H2B type 1-K, ... | | 著者 | Zebin, T, Ai, H.S, Ziyu, X, Man, P, Liu, L. | | 登録日 | 2022-12-14 | | 公開日 | 2023-09-13 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.02 Å) | | 主引用文献 | Synovial sarcoma X breakpoint 1 protein uses a cryptic groove to selectively recognize H2AK119Ub nucleosomes.
Nat.Struct.Mol.Biol., 31, 2024
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8HQY
 | | Cryo-EM structure of SSX1 bound to the H2AK119Ub nucleosome at a resolution of 3.05 angstrom | | 分子名称: | DNA (136-MER), DNA (137-MER), Histone H2A type 1-B/E, ... | | 著者 | Zebin, T, Ai, H.S, Ziyu, X, GuoChao, C, Man, P, Liu, L. | | 登録日 | 2022-12-14 | | 公開日 | 2023-09-27 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.05 Å) | | 主引用文献 | Synovial sarcoma X breakpoint 1 protein uses a cryptic groove to selectively recognize H2AK119Ub nucleosomes.
Nat.Struct.Mol.Biol., 31, 2024
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8G6G
 | | H2BK120ub+H3K79me2-modified nucleosome ubiquitin position 5 | | 分子名称: | 601 DNA (185-MER), Histone H2A, Histone H2B 1.1, ... | | 著者 | Hicks, C.W, Wolberger, C, Keogh, M. | | 登録日 | 2023-02-15 | | 公開日 | 2024-02-21 | | 最終更新日 | 2024-09-25 | | 実験手法 | ELECTRON MICROSCOPY (2.93 Å) | | 主引用文献 | Ubiquitinated histone H2B as gatekeeper of the nucleosome acidic patch.
Nucleic Acids Res., 52, 2024
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8G6Q
 | | H2AK119ub-modified nucleosome ubiquitin position 1 | | 分子名称: | 601 DNA (147-MER), Histone H2A, Histone H2B 1.1, ... | | 著者 | Hicks, C.W, Wolberger, C, Keogh, M. | | 登録日 | 2023-02-15 | | 公開日 | 2024-02-21 | | 最終更新日 | 2024-09-25 | | 実験手法 | ELECTRON MICROSCOPY (3.41 Å) | | 主引用文献 | Ubiquitinated histone H2B as gatekeeper of the nucleosome acidic patch.
Nucleic Acids Res., 52, 2024
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8G6S
 | | H2AK119ub-modified nucleosome ubiquitin position 2 | | 分子名称: | 601 DNA (147-MER), Histone H2A, Histone H2B 1.1, ... | | 著者 | Hicks, C.W, Wolberger, C, Keogh, M. | | 登録日 | 2023-02-15 | | 公開日 | 2024-02-21 | | 最終更新日 | 2024-09-25 | | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | | 主引用文献 | Ubiquitinated histone H2B as gatekeeper of the nucleosome acidic patch.
Nucleic Acids Res., 52, 2024
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7E8D
 | | NSD2 E1099K mutant bound to nucleosome | | 分子名称: | DNA (185-MER), Histone H2A type 1, Histone H2B type 1-J, ... | | 著者 | Sengoku, T, Sato, K, Nishizawa, T, Nureki, O, Ogata, K. | | 登録日 | 2021-03-01 | | 公開日 | 2021-11-10 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | Structural basis of the regulation of the normal and oncogenic methylation of nucleosomal histone H3 Lys36 by NSD2.
Nat Commun, 12, 2021
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4QEZ
 | | Crystal structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Bacillus anthracis | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase, ADENINE | | 著者 | Tarique, K.F, Devi, S, Abdul Rehman, S.A, Gourinath, S. | | 登録日 | 2014-05-19 | | 公開日 | 2014-06-18 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Crystal structure of 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Bacillus anthracis
To be Published
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2Z83
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7VDV
 | | The overall structure of human chromatin remodeling PBAF-nucleosome complex | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, AT-rich interactive domain-containing protein 2,AT-rich interactive domain-containing protein 2, Actin, ... | | 著者 | Chen, Z.C, Chen, K.J, Yuan, J.J. | | 登録日 | 2021-09-07 | | 公開日 | 2022-05-18 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structure of human chromatin-remodelling PBAF complex bound to a nucleosome.
Nature, 605, 2022
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8KB5
 | | Cryo-EM structure of the human nucleosome containing H3.8 | | 分子名称: | DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | | 著者 | Hirai, H, Kujirai, T, Takizawa, Y, Kurumizaka, H. | | 登録日 | 2023-08-03 | | 公開日 | 2023-10-18 | | 最終更新日 | 2023-12-27 | | 実験手法 | ELECTRON MICROSCOPY (2.26133 Å) | | 主引用文献 | Cryo-EM and biochemical analyses of the nucleosome containing the human histone H3 variant H3.8.
J.Biochem., 174, 2023
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8EVJ
 | | CX3CR1 nucleosome bound PU.1 and C/EBPa | | 分子名称: | DNA (167-MER), Histone H2A type 2-C, Histone H2B type 2-E, ... | | 著者 | Guan, R, Bai, Y, Lian, T. | | 登録日 | 2022-10-20 | | 公開日 | 2023-11-01 | | 最終更新日 | 2024-10-30 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Structural mechanism of synergistic targeting of the CX3CR1 nucleosome by PU.1 and C/EBP alpha.
Nat.Struct.Mol.Biol., 31, 2024
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8EVI
 | | CX3CR1 nucleosome and PU.1 complex containing disulfide bond mutations | | 分子名称: | DNA (167-MER), Histone H2A type 2-C, Histone H2B type 2-E, ... | | 著者 | Lian, T, Guan, R, Bai, Y. | | 登録日 | 2022-10-20 | | 公開日 | 2023-11-01 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (2.64 Å) | | 主引用文献 | Structural mechanism of synergistic targeting of the CX3CR1 nucleosome by PU.1 and C/EBP alpha.
Nat.Struct.Mol.Biol., 31, 2024
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5C8L
 | | Crystal Structure of the Bdellovibrio bacteriovorus Nucleoside Diphosphate Sugar Hydrolase | | 分子名称: | DI(HYDROXYETHYL)ETHER, GLYCEROL, NudF protein, ... | | 著者 | Gabelli, S.B, de la Pena, A.H, Suarez, A, Amzel, L.M. | | 登録日 | 2015-06-25 | | 公開日 | 2016-01-20 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural and Enzymatic Characterization of a Nucleoside Diphosphate Sugar Hydrolase from Bdellovibrio bacteriovorus.
Plos One, 10, 2015
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6KVD
 | | Crystal structure of human nucleosome containing H2A.J | | 分子名称: | CHLORIDE ION, DNA (146-MER), Histone H2A.J, ... | | 著者 | Tanaka, H, Koyama, M, Sato, S, Kujirai, T, Kurumizaka, H. | | 登録日 | 2019-09-04 | | 公開日 | 2019-12-18 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | | 主引用文献 | Biochemical and structural analyses of the nucleosome containing human histone H2A.J.
J.Biochem., 167, 2020
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