PDB: 66478 件ウェブページステータス検索Chemie searchBIRD

---

6YP2	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-011 分子名称: 1-(4-methylphenyl)imidazole, 14-3-3 protein sigma, CHLORIDE ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2020-04-15 公開日 2020-09-23 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Fragment-Based Stabilizers of Protein-Protein Interactions through Imine-Based Tethering. Angew.Chem.Int.Ed.Engl., 59, 2020
6L2Q	Threonyl-tRNA synthetase from Salmonella enterica in complex with an inhibitor 分子名称: (2S,3R)-2-azanyl-N-[(E)-4-[6,7-bis(chloranyl)-4-oxidanylidene-quinazolin-3-yl]but-2-enyl]-3-oxidanyl-butanamide, 1,2-ETHANEDIOL, Threonine--tRNA ligase, ... 著者 Guo, J, Chen, B, Zhou, H. 登録日 2019-10-05 公開日 2020-01-15 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Discovery of novel tRNA-amino acid dual-site inhibitors against threonyl-tRNA synthetase by fragment-based target hopping. Eur.J.Med.Chem., 187, 2019
6YQT	CRYSTAL STRUCTURE OF HUMAN CA II IN COMPLEX WITH A SULFONAMIDE DERIVATIVE OF 2-MERCAPTOBENZOXAZOLE 分子名称: 2-sulfanylidene-3~{H}-1,3-benzoxazole-5-sulfonamide, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... 著者 Alterio, V, De Simone, G, Esposito, D. 登録日 2020-04-18 公開日 2020-07-01 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 2-Mercaptobenzoxazoles: a class of carbonic anhydrase inhibitors with a novel binding mode to the enzyme active site. Chem.Commun.(Camb.), 56, 2020
6L7H	crystal structure of GgCGT in complex with UDP and Nothofagin 分子名称: 1-[3-[(2S,3R,4R,5S,6R)-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]-2,4,6-tris(oxidanyl)phenyl]-3-(4-hydroxyphenyl)propan-1-one, GgCGT1, URIDINE-5'-DIPHOSPHATE 著者 Zhang, M, Li, F.D, Ye, M. 登録日 2019-11-01 公開日 2020-02-19 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Functional Characterization and Structural Basis of an Efficient Di-C-glycosyltransferase fromGlycyrrhiza glabra. J.Am.Chem.Soc., 142, 2020
6Y58	Binary complex of 14-3-3 sigma (C38N) with the Estrogen Related Receptor gamma (LBD) phosphopeptide 分子名称: 14-3-3 protein sigma, Estrogen Related Receptor gamma phosphopeptide, MAGNESIUM ION 著者 Somsen, B.A, Sijbesma, E, Leijten-van de Gevel, I.A, Ottmann, C. 登録日 2020-02-25 公開日 2020-11-18 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.904 Å) 主引用文献 Fluorescence Anisotropy-Based Tethering for Discovery of Protein-Protein Interaction Stabilizers. Acs Chem.Biol., 15, 2020
6YP3	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-028 分子名称: 1-(4-methylphenyl)-1,2,4-triazole, 14-3-3 protein sigma, CHLORIDE ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2020-04-15 公開日 2020-09-23 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Fragment-Based Stabilizers of Protein-Protein Interactions through Imine-Based Tethering. Angew.Chem.Int.Ed.Engl., 59, 2020
6YP8	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-033 分子名称: 14-3-3 protein sigma, 3-imidazol-1-ylbenzaldehyde, CHLORIDE ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2020-04-15 公開日 2020-09-23 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Fragment-Based Stabilizers of Protein-Protein Interactions through Imine-Based Tethering. Angew.Chem.Int.Ed.Engl., 59, 2020
6YLO	mTurquoise2 - Directionality of Optical Properties of Fluorescent Proteins 分子名称: POTASSIUM ION, TETRAETHYLENE GLYCOL, mTurquoise2_C2221 著者 Myskova, J, Rybakova, O, Brynda, J, Lazar, J. 登録日 2020-04-07 公開日 2020-12-16 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Directionality of light absorption and emission in representative fluorescent proteins. Proc.Natl.Acad.Sci.USA, 117, 2020
6YLS	mEos4b - Directionality of Optical Properties of Fluorescent Proteins 分子名称: CHLORIDE ION, Green to red photoconvertible GFP-like protein EosFP, SODIUM ION 著者 Myskova, J, Rybakova, O, Brynda, J, Lazar, J. 登録日 2020-04-07 公開日 2020-12-16 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Directionality of light absorption and emission in representative fluorescent proteins. Proc.Natl.Acad.Sci.USA, 117, 2020
5CFU	Crystal Structure of ANT(2")-Ia in complex with adenylyl-2"-tobramycin 分子名称: 1,4-BUTANEDIOL, Aminoglycoside Nucleotidyltransferase (2")-Ia, MANGANESE (II) ION, ... 著者 Rodionov, D, Bassenden, A.V, Berghuis, A.M. 登録日 2015-07-08 公開日 2016-07-20 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.82 Å) 主引用文献 Revisiting the Catalytic Cycle and Kinetic Mechanism of AminoglycosideO-Nucleotidyltransferase(2′′): A Structural and Kinetic Study. Acs Chem.Biol., 2020
6Y44	14-3-3 Sigma in complex with phosphorylated SOS1 peptide 分子名称: 14-3-3 protein sigma, CALCIUM ION, CHLORIDE ION, ... 著者 Ballone, A, Lau, R.A, Zweipfenning, F.P.A, Ottmann, C. 登録日 2020-02-19 公開日 2020-10-14 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.71 Å) 主引用文献 A new soaking procedure for X-ray crystallographic structural determination of protein-peptide complexes. Acta Crystallogr.,Sect.F, 76, 2020
6M1I	CryoEM structure of human PAC1 receptor in complex with PACAP38 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... 著者 Song, X, Wang, J, Zhang, D, Wang, H.W, Ma, Y. 登録日 2020-02-26 公開日 2020-03-11 最終更新日 2020-05-27 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Cryo-EM structures of PAC1 receptor reveal ligand binding mechanism. Cell Res., 30, 2020
6BBR	Room temperature neutron/X-ray structure of AAC-VIa 分子名称: AAC 3-VI protein, MAGNESIUM ION 著者 Cuneo, M.J, Kumar, P, Serpersu, E.H. 登録日 2017-10-19 公開日 2018-02-28 最終更新日 2023-10-04 実験手法 NEUTRON DIFFRACTION (2.002 Å), X-RAY DIFFRACTION 主引用文献 A low-barrier hydrogen bond mediates antibiotic resistance in a noncanonical catalytic triad. Sci Adv, 4, 2018
3RE9	Crystal structure of sortaseC1 from Streptococcus suis 分子名称: Sortase-like protein 著者 Lu, G, Qi, J, Gao, F, Yan, J, Tang, J, Gao, G.F. 登録日 2011-04-04 公開日 2011-06-01 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 A novel "open-form" structure of sortaseC from Streptococcus suis. Proteins, 79, 2011
5CEE	Malic enzyme from Candidatus Phytoplasma AYWB in complex with NAD and Mg2+ 分子名称: MAGNESIUM ION, NAD-dependent malic enzyme, NICOTINAMIDE-ADENINE-DINUCLEOTIDE 著者 Alvarez, C.E, Trajtenberg, F, Larrieux, N, Saigo, M, Mussi, M.A, Andreo, C.S, Drincovich, M.F, Buschiazzo, A. 登録日 2015-07-06 公開日 2016-10-05 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.498 Å) 主引用文献 The crystal structure of the malic enzyme from Candidatus Phytoplasma reveals the minimal structural determinants for a malic enzyme. Acta Crystallogr D Struct Biol, 74, 2018
6YEM	H1N1 2009 PA Endonuclease in complex with Quambalarine B 分子名称: 3,5,6,8-tetrakis(oxidanyl)-2-pentanoyl-naphthalene-1,4-dione, CHLORIDE ION, MAGNESIUM ION, ... 著者 Radilova, K, Brynda, J. 登録日 2020-03-25 公開日 2020-09-09 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Unraveling the anti-influenza effect of flavonoids: Experimental validation of luteolin and its congeners as potent influenza endonuclease inhibitors. Eur.J.Med.Chem., 208, 2020
6YHU	Crystal structure of the nsp7-nsp8 complex of SARS-CoV-2 分子名称: Replicase polyprotein 1a 著者 Konkolova, E, Klima, M, Boura, E. 登録日 2020-03-31 公開日 2020-04-29 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural analysis of the putative SARS-CoV-2 primase complex. J.Struct.Biol., 211, 2020
6MFE	Schistosoma mansoni (Blood Fluke) Sulfotransferase/CIDD-0000773 (Compound 11g) Complex 分子名称: (2-nitro-4-{[(3S)-1-{[4-(trifluoromethoxy)phenyl]methyl}pyrrolidin-3-yl]amino}phenyl)methanol, ADENOSINE-3'-5'-DIPHOSPHATE, Sulfotransferase oxamniquine resistance protein 著者 Taylor, A.B. 登録日 2018-09-10 公開日 2018-10-03 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.444 Å) 主引用文献 Design, Synthesis, and Characterization of Novel Small Molecules as Broad Range Antischistosomal Agents. ACS Med Chem Lett, 9, 2018
3SQH	Crystal structure of prethrombin-2 mutant S195A in the the open form 分子名称: Thrombin light chain, heavy chain 著者 Pozzi, N, Chen, Z, Di Cera, E. 登録日 2011-07-05 公開日 2011-11-30 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structures of prethrombin-2 reveal alternative conformations under identical solution conditions and the mechanism of zymogen activation. Biochemistry, 50, 2011
6MG1	C-terminal bZIP domain of human C/EBPbeta with 16bp Methylated Oligonucleotide Containing Consensus Recognition Sequence-C2 Crystal Form 分子名称: 1,2-ETHANEDIOL, 16-bp methylated oligonucleotide, CCAAT/enhancer-binding protein beta, ... 著者 Horton, J.R, Cheng, X, Yang, J. 登録日 2018-09-12 公開日 2018-12-12 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Structural basis for effects of CpA modifications on C/EBP beta binding of DNA. Nucleic Acids Res., 47, 2019
6YPL	14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-037 分子名称: (2-methylsulfonylphenyl)methanol, 14-3-3 protein sigma, CHLORIDE ION, ... 著者 Wolter, M, Ottmann, C. 登録日 2020-04-16 公開日 2020-09-23 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Fragment-Based Stabilizers of Protein-Protein Interactions through Imine-Based Tethering. Angew.Chem.Int.Ed.Engl., 59, 2020
6YQU	CRYSTAL STRUCTURE OF HUMAN CA II IN COMPLEX WITH 2-MERCAPTOBENZOXAZOLE 分子名称: 3~{H}-1,3-benzoxazole-2-thione, Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ... 著者 Alterio, V, De Simone, G, Esposito, D. 登録日 2020-04-18 公開日 2020-07-01 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.478 Å) 主引用文献 2-Mercaptobenzoxazoles: a class of carbonic anhydrase inhibitors with a novel binding mode to the enzyme active site. Chem.Commun.(Camb.), 56, 2020
6MAL	Structure of human Nocturnin C-terminal domain 分子名称: MAGNESIUM ION, Nocturnin 著者 Estrella, M.A, Du, J, Korennykh, A. 登録日 2018-08-28 公開日 2018-09-05 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal Structure of Human Nocturnin Catalytic Domain. Sci Rep, 8, 2018
6MB8	Apo structure of AAC-IIIb 分子名称: Aac(3)-IIIb protein, CHLORIDE ION 著者 Cuneo, M.J, Kumar, P. 登録日 2018-08-29 公開日 2018-11-07 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Encoding of Promiscuity in an Aminoglycoside Acetyltransferase. J. Med. Chem., 61, 2018
3STF	Crystal structure of a mutant (S211A) of 3-deoxy-D-manno-octulosonate 8-phosphate synthase (KDO8PS) from Neisseria meningitidis 分子名称: 2-dehydro-3-deoxyphosphooctonate aldolase, CHLORIDE ION, GLYCEROL, ... 著者 Allison, T.M, Jameson, G.B, Gloyne, B.J, Parker, E.J. 登録日 2011-07-09 公開日 2011-11-23 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 An Extended (beta)7(alpha)7 Substrate-Binding Loop Is Essential for Efficient Catalysis by 3-Deoxy-D-manno-Octulosonate 8-Phosphate Synthase Biochemistry, 50, 2011

<342343344345346347348349350351352353354355356357>