6YP2
14-3-3 sigma with RelA/p65 binding site pS45 and covalently bound TCF521-011
Summary for 6YP2
Entry DOI | 10.2210/pdb6yp2/pdb |
Related | 6QHL |
Descriptor | 14-3-3 protein sigma, p65pS45, CHLORIDE ION, ... (5 entities in total) |
Functional Keywords | covalent fragment, p65, 1433, peptide binding protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 28178.98 |
Authors | Wolter, M.,Ottmann, C. (deposition date: 2020-04-15, release date: 2020-09-23, Last modification date: 2024-01-24) |
Primary citation | Wolter, M.,Valenti, D.,Cossar, P.J.,Levy, L.M.,Hristeva, S.,Genski, T.,Hoffmann, T.,Brunsveld, L.,Tzalis, D.,Ottmann, C. Fragment-Based Stabilizers of Protein-Protein Interactions through Imine-Based Tethering. Angew.Chem.Int.Ed.Engl., 59:21520-21524, 2020 Cited by PubMed: 32816380DOI: 10.1002/anie.202008585 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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