4FLJ
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![BU of 4flj by Molmil](/molmil-images/mine/4flj) | Human MetAP1 with bengamide analog Y08, in Mn form | 分子名称: | (E,2R,3R,4S,5R)-N-[[(3S)-1-cyclopropylcarbonylpiperidin-3-yl]methyl]-2-methoxy-8,8-dimethyl-3,4,5-tris(oxidanyl)non-6-enamide, MANGANESE (II) ION, Methionine aminopeptidase 1, ... | 著者 | Ye, Q.Z, Xu, W. | 登録日 | 2012-06-14 | 公開日 | 2012-09-19 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | 主引用文献 | Structural analysis of bengamide derivatives as inhibitors of methionine aminopeptidases. J.Med.Chem., 55, 2012
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4FQ9
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![BU of 4fq9 by Molmil](/molmil-images/mine/4fq9) | Crystal Structure of 3-hydroxydecanoyl-Acyl Carrier Protein Dehydratase (FabA) from Pseudomonas aeruginosa | 分子名称: | 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase, GLYCEROL, PHOSPHATE ION | 著者 | Moynie, L, Mcmahon, S.A, Duthie, F.G, Naismith, J.H. | 登録日 | 2012-06-25 | 公開日 | 2013-03-27 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | Structural insights into the mechanism and inhibition of the beta-hydroxydecanoyl-acyl carrier protein dehydratase from Pseudomonas aeruginosa J.Mol.Biol., 425, 2013
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2P05
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![BU of 2p05 by Molmil](/molmil-images/mine/2p05) | Structural Insights into the Evolution of a Non-Biological Protein | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, PENTAETHYLENE GLYCOL, ... | 著者 | Smith, M, Rosenow, M, Wang, M, Allen, J.P, Szostak, J.W, Chaput, J.C. | 登録日 | 2007-02-28 | 公開日 | 2007-06-05 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural insights into the evolution of a non-biological protein: importance of surface residues in protein fold optimization. PLoS ONE, 2, 2007
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3TE8
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![BU of 3te8 by Molmil](/molmil-images/mine/3te8) | |
3GCN
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![BU of 3gcn by Molmil](/molmil-images/mine/3gcn) | |
4FRA
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![BU of 4fra by Molmil](/molmil-images/mine/4fra) | Crystal Structure of ABBA+UDP+Gal at pH 5.0 with MPD as the cryoprotectant | 分子名称: | DI(HYDROXYETHYL)ETHER, Histo-blood group ABO system transferase, URIDINE-5'-DIPHOSPHATE, ... | 著者 | Johal, A.R, Alfaro, J.A, Blackler, R.J, Schuman, B, Borisova, S.N, Evans, S.V. | 登録日 | 2012-06-26 | 公開日 | 2013-12-25 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | 主引用文献 | pH-induced conformational changes in human ABO(H) blood group glycosyltransferases confirm the importance of electrostatic interactions in the formation of the semi-closed state. Glycobiology, 24, 2014
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4FOG
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![BU of 4fog by Molmil](/molmil-images/mine/4fog) | Crystal Structure of Mtb ThyA in Complex with 5-Fluoro-dUMP and 5-methyltetrahydrofolic acid | 分子名称: | 5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, 5-METHYL-5,6,7,8-TETRAHYDROFOLIC ACID, Thymidylate synthase | 著者 | Reddy, M.C.M, Bruning, J.B, Harshbarger, W, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2012-06-20 | 公開日 | 2013-08-07 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structure of binary and ternary complexes of thymidylate synthase (ThyA) from Mycobacterium tuberculosis: Insights into the selectivity and mode of inhibition To be Published
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4FPK
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3GEG
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![BU of 3geg by Molmil](/molmil-images/mine/3geg) | Fingerprint and Structural Analysis of a SCOR enzyme with its bound cofactor from Clostridium thermocellum | 分子名称: | GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SODIUM ION, ... | 著者 | Huether, R, Liu, Z.J, Xu, H, Wang, B.C, Pletnev, V, Mao, Q, Umland, T, Duax, W. | 登録日 | 2009-02-25 | 公開日 | 2009-03-17 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.102 Å) | 主引用文献 | Sequence fingerprint and structural analysis of the SCOR enzyme A3DFK9 from Clostridium thermocellum. Proteins, 78, 2010
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3SQB
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![BU of 3sqb by Molmil](/molmil-images/mine/3sqb) | Structure of the major type 1 pilus subunit FimA bound to the FimC chaperone | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Chaperone protein fimC, ... | 著者 | Scharer, M.A, Eidam, O, Grutter, M.G, Glockshuber, R, Capitani, G. | 登録日 | 2011-07-05 | 公開日 | 2012-05-30 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Quality control of disulfide bond formation in pilus subunits by the chaperone FimC. Nat.Chem.Biol., 8, 2012
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2PF6
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![BU of 2pf6 by Molmil](/molmil-images/mine/2pf6) | |
3GFT
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![BU of 3gft by Molmil](/molmil-images/mine/3gft) | Human K-Ras (Q61H) in complex with a GTP analogue | 分子名称: | CITRIC ACID, GTPase KRas, MAGNESIUM ION, ... | 著者 | Tong, Y, Tempel, W, Shen, L, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | 登録日 | 2009-02-27 | 公開日 | 2009-03-10 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | 主引用文献 | Human K-Ras in complex with a GTP analogue To be Published
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4FM9
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![BU of 4fm9 by Molmil](/molmil-images/mine/4fm9) | Human topoisomerase II alpha bound to DNA | 分子名称: | DNA (5'-D(*CP*GP*CP*GP*CP*AP*TP*CP*GP*TP*CP*AP*TP*CP*CP*TP*C)-3'), DNA (5'-D(P*GP*AP*GP*GP*AP*TP*GP*AP*CP*GP*AP*TP*G)-3'), DNA topoisomerase 2-alpha, ... | 著者 | Wendorff, T.J, Schmidt, B.H, Heslop, P, Austin, C.A, Berger, J.M. | 登録日 | 2012-06-15 | 公開日 | 2012-08-08 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.901 Å) | 主引用文献 | The Structure of DNA-Bound Human Topoisomerase II Alpha: Conformational Mechanisms for Coordinating Inter-Subunit Interactions with DNA Cleavage. J.Mol.Biol., 424, 2012
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3CTW
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2OVF
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![BU of 2ovf by Molmil](/molmil-images/mine/2ovf) | Crystal Structure of StaL-PAP complex | 分子名称: | ADENOSINE-3'-5'-DIPHOSPHATE, StaL | 著者 | Shi, R, Matte, A, Cygler, M, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | 登録日 | 2007-02-13 | 公開日 | 2007-02-27 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Crystal structure of StaL, a glycopeptide antibiotic sulfotransferase from Streptomyces toyocaensis. J.Biol.Chem., 282, 2007
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4FND
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![BU of 4fnd by Molmil](/molmil-images/mine/4fnd) | Crystal structure of the Mtb enoyl CoA isomerase in complex with hydroxyhexanoyl CoA | 分子名称: | (S)-3-Hydroxyhexanoyl-CoA, Enoyl-CoA hydratase/isomerase family protein, SULFATE ION | 著者 | Bruning, J.B, Gao, N, Hernandez, E.D, Li, H, Dang, N, Hung, L.W, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2012-06-19 | 公開日 | 2013-05-29 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Crystal structure and mechanism of the prokaryotic enoyl CoA isomerase To be Published
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3CW5
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![BU of 3cw5 by Molmil](/molmil-images/mine/3cw5) | E. coli Initiator tRNA | 分子名称: | Initiator tRNA | 著者 | Barraud, P, Schmitt, E, Mechulam, Y, Dardel, F, Tisne, C. | 登録日 | 2008-04-21 | 公開日 | 2008-09-02 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | A unique conformation of the anticodon stem-loop is associated with the capacity of tRNAfMet to initiate protein synthesis. Nucleic Acids Res., 36, 2008
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3STK
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2P72
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![BU of 2p72 by Molmil](/molmil-images/mine/2p72) | crystal structure of a glycosyltransferase involved in the glycosylation of the major capsid of PBCV-1 | 分子名称: | MANGANESE (II) ION, Putative glycosyltransferase (Mannosyltransferase) involved in glycosylating the PBCV-1 major capsid protein, URIDINE-5'-DIPHOSPHATE-GLUCOSE | 著者 | Zhang, Y, Xiang, Y, Van Etten, J.L, Rossmann, M.G. | 登録日 | 2007-03-19 | 公開日 | 2007-08-21 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure and function of a chlorella virus-encoded glycosyltransferase. Structure, 15, 2007
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4D8A
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![BU of 4d8a by Molmil](/molmil-images/mine/4d8a) | Crystal structure of B. anthracis DHPS with compound 21 | 分子名称: | Dihydropteroate synthase, LYSINE, SULFATE ION, ... | 著者 | Hammoudeh, D, Lee, R.E, White, S.W. | 登録日 | 2012-01-10 | 公開日 | 2012-04-04 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.183 Å) | 主引用文献 | Structure-Based Design of Novel Pyrimido[4,5-c]pyridazine Derivatives as Dihydropteroate Synthase Inhibitors with Increased Affinity. Chemmedchem, 7, 2012
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3CXN
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![BU of 3cxn by Molmil](/molmil-images/mine/3cxn) | Structure of the Urease Accessory Protein UreF from Helicobacter pylori | 分子名称: | GLYCEROL, Urease accessory protein ureF | 著者 | Lam, R, Johns, K, Romanov, V, Dong, A, Wu-Brown, J, Guthrie, J, Dharamsi, A, Thambipillai, D, Mansoury, K, Edwards, A.M, Pai, E.F, Chirgadze, N.Y. | 登録日 | 2008-04-24 | 公開日 | 2009-05-12 | 最終更新日 | 2017-10-25 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Crystal structure of a truncated urease accessory protein UreF from Helicobacter pylori. Proteins, 78, 2010
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4FOE
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![BU of 4foe by Molmil](/molmil-images/mine/4foe) | |
4D9P
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![BU of 4d9p by Molmil](/molmil-images/mine/4d9p) | Crystal structure of B. anthracis DHPS with compound 17 | 分子名称: | (3R)-3-(7-amino-1-methyl-4,5-dioxo-1,4,5,6-tetrahydropyrimido[4,5-c]pyridazin-3-yl)butanoic acid, Dihydropteroate Synthase, SULFATE ION | 著者 | Hammoudeh, D, Lee, R.E, White, S.W. | 登録日 | 2012-01-11 | 公開日 | 2012-03-28 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Structure-Based Design of Novel Pyrimido[4,5-c]pyridazine Derivatives as Dihydropteroate Synthase Inhibitors with Increased Affinity. Chemmedchem, 7, 2012
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4DA0
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![BU of 4da0 by Molmil](/molmil-images/mine/4da0) | Crystal structure of the hexameric purine nucleoside phosphorylase from Bacillus subtilis in complex with 2'-deoxyguanosine | 分子名称: | 2'-DEOXY-GUANOSINE, CHLORIDE ION, Purine nucleoside phosphorylase deoD-type | 著者 | Martins, N.H, Giuseppe, P.O, Meza, A.N, Murakami, M.T. | 登録日 | 2012-01-12 | 公開日 | 2012-09-26 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.95 Å) | 主引用文献 | Insights into phosphate cooperativity and influence of substrate modifications on binding and catalysis of hexameric purine nucleoside phosphorylases. Plos One, 7, 2012
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3SW5
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![BU of 3sw5 by Molmil](/molmil-images/mine/3sw5) | |