4RV7
| Characterization of an essential diadenylate cyclase | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Diadenylate cyclase, HEXANE-1,6-DIOL, ... | 著者 | Dickmanns, A, Neumann, P, Ficner, R. | 登録日 | 2014-11-25 | 公開日 | 2015-01-28 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural and Biochemical Analysis of the Essential Diadenylate Cyclase CdaA from Listeria monocytogenes. J.Biol.Chem., 290, 2015
|
|
3F3T
| Kinase domain of cSrc in complex with inhibitor RL38 (Type III) | 分子名称: | 1-[1-(3-aminophenyl)-3-tert-butyl-1H-pyrazol-5-yl]-3-naphthalen-1-ylurea, Proto-oncogene tyrosine-protein kinase Src | 著者 | Gruetter, C, Klueter, S, Getlik, M, Rauh, D. | 登録日 | 2008-10-31 | 公開日 | 2009-03-03 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | A new screening assay for allosteric inhibitors of cSrc Nat.Chem.Biol., 5, 2009
|
|
3EXX
| |
3EY4
| Further studies with the 2-amino-1,3-thiazol-4(5H)-one class of 11-hydroxysteroid dehydrogenase type 1 (11-HSD1) inhibitors: Reducing pregnane X receptor (PXR) activity and exploring activity in a monkey pharmacodynamic model | 分子名称: | (5S)-2-{[(1S)-1-(4-fluorophenyl)ethyl]amino}-5-(1-hydroxy-1-methylethyl)-5-methyl-1,3-thiazol-4(5H)-one, 11-beta-Hydroxysteroid Dehydrogenase 1, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | 著者 | Zhang, J.D, Jordan, S.R, Li, V. | 登録日 | 2008-10-17 | 公開日 | 2008-11-11 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Further studies with the 2-amino-1,3-thiazol-4(5H)-one class of 11-hydroxysteroid dehydrogenase type 1 (11-HSD1) inhibitors: Reducing pregnane X receptor (PXR) activity and exploring activity in a monkey pharmacodynamic model To be Published, 2008
|
|
4RW9
| Crystal Structure of HIV-1 Reverse Transcriptase (Y181C) variant in complex with (E)-3-(3-chloro-5-(2-(2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy)phenoxy)phenyl)acrylonitrile (JLJ532), a non-nucleoside inhibitor | 分子名称: | (2E)-3-(3-chloro-5-{2-[2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy]phenoxy}phenyl)prop-2-enenitrile, Reverse transcriptase/ribonuclease H, p51 subunit, ... | 著者 | Frey, K.M, Anderson, K.S. | 登録日 | 2014-12-01 | 公開日 | 2015-04-29 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.986 Å) | 主引用文献 | Structure-Based Evaluation of Non-nucleoside Inhibitors with Improved Potency and Solubility That Target HIV Reverse Transcriptase Variants. J.Med.Chem., 58, 2015
|
|
4RXY
| |
4RYS
| |
3EZ4
| |
4S3Q
| Amylomaltase MalQ from Escherichia coli in complex with maltose | 分子名称: | 1,2-ETHANEDIOL, 4-alpha-glucanotransferase, IODIDE ION, ... | 著者 | Weiss, S.C, Schiefner, A. | 登録日 | 2015-03-26 | 公開日 | 2015-07-08 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural Basis for the Interconversion of Maltodextrins by MalQ, the Amylomaltase of Escherichia coli. J.Biol.Chem., 290, 2015
|
|
4S13
| Ferulic Acid Decarboxylase (FDC1) | 分子名称: | 4-ethenylphenol, Ferulic acid decarboxylase 1 | 著者 | Lee, S.G, Bhuiya, M.W, Yu, O, Jez, J.M. | 登録日 | 2015-01-07 | 公開日 | 2015-05-06 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.348 Å) | 主引用文献 | Structure and Mechanism of Ferulic Acid Decarboxylase (FDC1) from Saccharomyces cerevisiae. Appl.Environ.Microbiol., 81, 2015
|
|
4RLJ
| Crystal Structure of (3R)-hydroxyacyl-ACP dehydratase HadAB hetero-dimer from Mycobacterium tuberculosis | 分子名称: | (3R)-hydroxyacyl-ACP dehydratase subunit HadA, (3R)-hydroxyacyl-ACP dehydratase subunit HadB, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, ... | 著者 | Li, J, Dong, Y, Rao, Z.H. | 登録日 | 2014-10-17 | 公開日 | 2015-10-21 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Molecular basis for the inhibition of beta-hydroxyacyl-ACP dehydratase HadAB complex from Mycobacterium tuberculosis by flavonoid inhibitors. Protein Cell, 6, 2015
|
|
3F8L
| Crystal Structure of the Effector Domain of PhnF from Mycobacterium smegmatis | 分子名称: | GLYCEROL, HTH-type transcriptional repressor phnF, SULFATE ION | 著者 | Busby, J.N, Gebhard, S, Cook, G.M, Baker, E.N, Lott, S.J, Money, V.A. | 登録日 | 2008-11-12 | 公開日 | 2009-11-17 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of PhnF, a GntR-family transcription regulator in Mycobacterium smegmatis To be Published
|
|
3F99
| W354F Yersinia enterocolitica PTPase apo form | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase yopH | 著者 | Brandao, T.A.S, Robinson, H, Johnson, S.J, Hengge, A.C. | 登録日 | 2008-11-13 | 公開日 | 2009-01-20 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Impaired acid catalysis by mutation of a protein loop hinge residue in a YopH mutant revealed by crystal structures. J.Am.Chem.Soc., 131, 2009
|
|
3FB1
| |
4RQB
| |
3FCK
| Complex of UNG2 and a fragment-based design inhibitor | 分子名称: | 3-({[3-({[(1E)-(2,6-dioxo-1,2,3,6-tetrahydropyrimidin-4-yl)methylidene]amino}oxy)propyl]amino}methyl)benzoic acid, Uracil-DNA glycosylase | 著者 | Bianchet, M.A, Chung, S, Parker, J.B, Amzel, L.M, Stivers, J.T. | 登録日 | 2008-11-21 | 公開日 | 2009-04-28 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Impact of linker strain and flexibility in the design of a fragment-based inhibitor Nat.Chem.Biol., 5, 2009
|
|
3FEH
| Crystal structure of full length centaurin alpha-1 | 分子名称: | Centaurin-alpha-1, UNKNOWN ATOM OR ION, ZINC ION | 著者 | Shen, L, Tong, Y, Tempel, W, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) | 登録日 | 2008-11-29 | 公開日 | 2008-12-23 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Phosphorylation-independent dual-site binding of the FHA domain of KIF13 mediates phosphoinositide transport via centaurin {alpha}1. Proc.Natl.Acad.Sci.USA, 107, 2010
|
|
4RWB
| Racemic influenza M2-TM crystallized from monoolein lipidic cubic phase | 分子名称: | Matrix protein 2, [(Z)-octadec-9-enyl] (2R)-2,3-bis(oxidanyl)propanoate | 著者 | Mortenson, D.E, Steinkruger, J.D, Kreitler, D.F, Gellman, S.H, Forest, K.T. | 登録日 | 2014-12-02 | 公開日 | 2015-10-14 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | High-resolution structures of a heterochiral coiled coil. Proc.Natl.Acad.Sci.USA, 112, 2015
|
|
3F0Z
| |
3WIP
| Crystal structure of acetylcholine bound to Ls-AChBP | 分子名称: | ACETATE ION, ACETYLCHOLINE, Acetylcholine-binding protein, ... | 著者 | Olsen, J.A, Balle, T, Gajhede, M, Ahring, P.K, Kastrup, J.S. | 登録日 | 2013-09-24 | 公開日 | 2014-04-23 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Molecular recognition of the neurotransmitter acetylcholine by an acetylcholine binding protein reveals determinants of binding to nicotinic acetylcholine receptors Plos One, 9, 2014
|
|
3WJJ
| Crystal structure of IIb selective Fc variant, Fc(P238D), in complex with FcgRIIb | 分子名称: | Ig gamma-1 chain C region, Low affinity immunoglobulin gamma Fc region receptor II-b, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Kadono, S, Mimoto, F, Katada, H, Igawa, T, Kuramochi, T, Muraoka, M, Wada, Y, Haraya, K, Miyazaki, T, Hattori, K. | 登録日 | 2013-10-10 | 公開日 | 2013-11-13 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Engineered antibody Fc variant with selectively enhanced Fc gamma RIIb binding over both Fc gamma RIIaR131 and Fc gamma RIIaH131. Protein Eng.Des.Sel., 26, 2013
|
|
3GH1
| Crystal structure of predicted nucleotide-binding protein from Vibrio cholerae | 分子名称: | PHOSPHATE ION, Predicted nucleotide-binding protein | 著者 | Malashkevich, V.N, Toro, R, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2009-03-02 | 公開日 | 2009-03-10 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of predicted nucleotide-binding protein from Vibrio cholerae. To be Published
|
|
3WP3
| |
3GJA
| CytC3 | 分子名称: | ACETATE ION, CytC3 | 著者 | Wong, C, Drennan, C.L. | 登録日 | 2009-03-08 | 公開日 | 2009-04-14 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural analysis of an open active site conformation of nonheme iron halogenase CytC3 J.Am.Chem.Soc., 131, 2009
|
|
3GAD
| Structure of apomif | 分子名称: | ACETIC ACID, Macrophage migration inhibitory factor-like protein, SULFATE ION | 著者 | Zhou, Y.-F, Su, X.-D, Shao, D, Wang, H. | 登録日 | 2009-02-17 | 公開日 | 2009-12-29 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural and functional comparison of MIF ortholog from Plasmodium yoelii with MIF from its rodent host Mol.Immunol., 47, 2010
|
|