8IOW
 
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7AJ6
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8J6F
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8IUZ
 | | H7N9 HA-2D7 Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2D7 Fab heavy chain, 2D7 Fab light chain, ... | | 著者 | Zhao, B.B, Sun, Z.Z. | | 登録日 | 2023-03-25 | | 公開日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | H7N9 HA-2D7 Fab
To Be Published
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8IUY
 | | H7N9 HA-1H9 Fab | | 分子名称: | 1H9 Fab heavy chain, 1H9 Fab light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Zhao, B.B, Sun, Z.Z. | | 登録日 | 2023-03-25 | | 公開日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | H7N9 HA-1H9 Fab
To Be Published
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7C02
 | | Crystal structure of dimeric MERS-CoV receptor binding domain | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | | 著者 | Dai, L, Qi, J, Gao, G.F. | | 登録日 | 2020-04-30 | | 公開日 | 2020-07-29 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.91 Å) | | 主引用文献 | A Universal Design of Betacoronavirus Vaccines against COVID-19, MERS, and SARS.
Cell, 182, 2020
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5AAO
 | | Crystal structure of fluorogen-activating designed ankyrin repeat protein (DARPin) dimer in complex with malachite green | | 分子名称: | 4-[[4-(dimethylamino)cyclohexa-2,5-dien-1-ylidene]-(4-methoxyphenyl)methyl]-N,N-dimethyl-aniline, FAD3210 | | 著者 | Batyuk, A, Schuetz, M, Kummer, L, Wu, Y, Mittl, P, Plueckthun, A. | | 登録日 | 2015-07-27 | | 公開日 | 2016-02-03 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Generation of Fluorogen-Activating Designed Ankyrin Repeat Proteins (FADAs) as Versatile Sensor Tools.
J. Mol. Biol., 428, 2016
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8IV0
 | | H7N9 HA-C4H4 Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, C4H4 Fab heavy chain, C4H4 Fab light chain, ... | | 著者 | Zhao, B.B, Sun, Z.Z. | | 登録日 | 2023-03-25 | | 公開日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | H7N9 HA-C4H4 Fab
To Be Published
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7ZG0
 | | Murine IL-27 in complex with IL-27Ra and a non-competing Nb | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-27 receptor subunit alpha, ... | | 著者 | Skladanowska, K, Bloch, Y, Savvides, S.N. | | 登録日 | 2022-04-01 | | 公開日 | 2022-11-02 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (3.18 Å) | | 主引用文献 | Structural basis of activation and antagonism of receptor signaling mediated by interleukin-27.
Cell Rep, 41, 2022
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5C1M
 | | Crystal structure of active mu-opioid receptor bound to the agonist BU72 | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2R,3S,3aR,5aR,6R,11bR,11cS)-3a-methoxy-3,14-dimethyl-2-phenyl-2,3,3a,6,7,11c-hexahydro-1H-6,11b-(epiminoethano)-3,5a-methanonaphtho[2,1-g]indol-10-ol, CHOLESTEROL, ... | | 著者 | Huang, W.J, Manglik, A, Venkatakrishnan, A.J, Laeremans, T, Feinberg, E.N, Sanborn, A.L, Kato, H.E, Livingston, K.E, Thorsen, T.S, Kling, R, Granier, S, Gmeiner, P, Husbands, S.M, Traynor, J.R, Weis, W.I, Steyaert, J, Dror, R.O, Kobilka, B.K. | | 登録日 | 2015-06-15 | | 公開日 | 2015-08-05 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | | 主引用文献 | Structural insights into mu-opioid receptor activation.
Nature, 524, 2015
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8A58
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5B1R
 | | Crystal structure of mouse CD72a CTLD | | 分子名称: | ACETATE ION, B-cell differentiation antigen CD72, GLYCEROL | | 著者 | Shinagawa, K, Numoto, N, Tsubata, T, Ito, N. | | 登録日 | 2015-12-15 | | 公開日 | 2016-10-19 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | CD72 negatively regulates B lymphocyte responses to the lupus-related endogenous toll-like receptor 7 ligand Sm/RNP
J.Exp.Med., 213, 2016
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8AAA
 | | Crystal structure of SARS-CoV-2 S RBD in complex with a stapled peptide | | 分子名称: | 1,1',1''-(1,3,5-triazinane-1,3,5-triyl)tripropan-1-one, Spike protein S1, Stapled peptide | | 著者 | Brear, P, Chen, L, Gaynor, K, Harman, M, Dods, R, Hyvonen, M. | | 登録日 | 2022-06-30 | | 公開日 | 2023-06-28 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Multivalent bicyclic peptides are an effective antiviral modality that can potently inhibit SARS-CoV-2.
Nat Commun, 14, 2023
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8AZT
 | | Type II amyloid-beta 42 filaments from high-spin supernatants of aqueous extracts from Alzheimer's disease brains | ABeta42 | | 分子名称: | Amyloid-beta precursor protein | | 著者 | Yang, Y, Stern, M.A, Meunier, L.A, Liu, W, Cai, Y.Q, Ericsson, M, Liu, L, Selkoe, J.D, Goedert, M, Scheres, H.W.S. | | 登録日 | 2022-09-06 | | 公開日 | 2022-11-02 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Abundant A beta fibrils in ultracentrifugal supernatants of aqueous extracts from Alzheimer's disease brains.
Neuron, 111, 2023
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7A56
 | | Schmallenberg Virus Envelope Glycoprotein Gc Fusion Domains in Postfusion Conformation | | 分子名称: | CHLORIDE ION, Envelopment polyprotein, PHOSPHATE ION, ... | | 著者 | Hellert, J, Guardado-Calvo, P, Rey, F.A. | | 登録日 | 2020-08-20 | | 公開日 | 2021-09-01 | | 最終更新日 | 2023-03-15 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structure, function, and evolution of the Orthobunyavirus membrane fusion glycoprotein.
Cell Rep, 42, 2023
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7A57
 | | La Crosse Virus Envelope Glycoprotein Gc W1066H Mutant Fusion Domains in Postfusion Conformation | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Envelopment polyprotein | | 著者 | Hellert, J, Guardado-Calvo, P, Rey, F.A. | | 登録日 | 2020-08-20 | | 公開日 | 2021-09-01 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (3.155 Å) | | 主引用文献 | Structure, function, and evolution of the Orthobunyavirus membrane fusion glycoprotein.
Cell Rep, 42, 2023
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8AZS
 | | Type I amyloid-beta 42 filaments from high-spin supernatants of aqueous extracts from Alzheimer's disease brains | ABeta42 | | 分子名称: | Amyloid-beta precursor protein | | 著者 | Yang, Y, Stern, M.A, Meunier, L.A, Liu, W, Cai, Y.Q, Ericsson, M, Liu, L, Selkoe, J.D, Goedert, M, Scheres, H.W.S. | | 登録日 | 2022-09-06 | | 公開日 | 2022-11-02 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Abundant A beta fibrils in ultracentrifugal supernatants of aqueous extracts from Alzheimer's disease brains.
Neuron, 111, 2023
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7BHE
 | | DARPin_D5/Her3 domain 4 complex, monoclinic crystals | | 分子名称: | ACETATE ION, DARPin_D5, GLYCEROL, ... | | 著者 | Mittl, P.R.E, Radom, F, Pluckthun, A. | | 登録日 | 2021-01-11 | | 公開日 | 2021-11-24 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.297 Å) | | 主引用文献 | Crystal structures of HER3 extracellular domain 4 in complex with the designed ankyrin-repeat protein D5.
Acta Crystallogr.,Sect.F, 77, 2021
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7BHF
 | | DARPin_D5/Her3 domain 4 complex, orthorhombic crystals | | 分子名称: | ACETATE ION, DARPin_D5, Isoform 4 of Receptor tyrosine-protein kinase erbB-3 | | 著者 | Mittl, P.R.E, Radom, F, Pluckthun, A. | | 登録日 | 2021-01-11 | | 公開日 | 2021-11-24 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.997 Å) | | 主引用文献 | Crystal structures of HER3 extracellular domain 4 in complex with the designed ankyrin-repeat protein D5.
Acta Crystallogr.,Sect.F, 77, 2021
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8AYH
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5AUM
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7YD0
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7YCY
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7YCZ
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5D41
 | | EGFR kinase domain in complex with mutant selective allosteric inhibitor | | 分子名称: | (2R)-2-(1-oxo-1,3-dihydro-2H-isoindol-2-yl)-2-phenyl-N-(1,3-thiazol-2-yl)acetamide, Epidermal growth factor receptor, MAGNESIUM ION, ... | | 著者 | Yun, C.-H, Park, E, Eck, M.J. | | 登録日 | 2015-08-07 | | 公開日 | 2016-06-08 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | Overcoming EGFR(T790M) and EGFR(C797S) resistance with mutant-selective allosteric inhibitors.
Nature, 534, 2016
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