2CS2
 
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7U4D
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7TRF
 | | Human telomerase catalytic core RNP with H2A/H2B | | 分子名称: | Histone H2A, Histone H2B type 1-C/E/F/G/I, Telomerase RNA, ... | | 著者 | Liu, B, He, Y, Wang, Y, Song, H, Zhou, Z.H, Feigon, J. | | 登録日 | 2022-01-28 | | 公開日 | 2022-04-20 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Structure of active human telomerase with telomere shelterin protein TPP1.
Nature, 604, 2022
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7TQL
 | | CryoEM structure of the human 40S small ribosomal subunit in complex with translation initiation factors eIF1A and eIF5B. | | 分子名称: | 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... | | 著者 | Lapointe, C.P, Grosely, R, Sokabe, M, Alvarado, C, Wang, J, Montabana, E, Villa, N, Shin, B, Dever, T, Fraser, C, Fernandez, I.S, Puglisi, J.D. | | 登録日 | 2022-01-26 | | 公開日 | 2022-04-27 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | eIF5B and eIF1A reorient initiator tRNA to allow ribosomal subunit joining.
Nature, 607, 2022
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3W98
 | | Crystal Structure of Human Nucleosome Core Particle lacking H3.1 N-terminal region | | 分子名称: | 146-mer DNA, Histone H2A type 1-B/E, Histone H2B type 1-J, ... | | 著者 | Iwasaki, W, Miya, Y, Horikoshi, N, Osakabe, A, Tachiwana, H, Shibata, T, Kagawa, W, Kurumizaka, H. | | 登録日 | 2013-04-01 | | 公開日 | 2013-08-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.42 Å) | | 主引用文献 | Contribution of histone N-terminal tails to the structure and stability of nucleosomes
FEBS Open Bio, 3, 2013
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7SYO
 | | Structure of the HCV IRES bound to the 40S ribosomal subunit, head open. Structure 9(delta dII) | | 分子名称: | 18S rRNA, 40S ribosomal protein S2, HCV IRES, ... | | 著者 | Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. | | 登録日 | 2021-11-25 | | 公開日 | 2022-07-27 | | 最終更新日 | 2022-08-24 | | 実験手法 | ELECTRON MICROSCOPY (4.6 Å) | | 主引用文献 | Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
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7SYS
 | | Structure of the delta dII IRES eIF2-containing 48S initiation complex, closed conformation. Structure 12(delta dII). | | 分子名称: | 18S rRNA, Eukaryotic translation initiation factor 1A, X-chromosomal, ... | | 著者 | Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. | | 登録日 | 2021-11-25 | | 公開日 | 2022-07-27 | | 最終更新日 | 2022-08-24 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
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7SYQ
 | | Structure of the wt IRES and 40S ribosome ternary complex, open conformation. Structure 11(wt) | | 分子名称: | 18S rRNA, Eukaryotic translation initiation factor 1A, X-chromosomal, ... | | 著者 | Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. | | 登録日 | 2021-11-25 | | 公開日 | 2022-07-27 | | 最終更新日 | 2022-08-24 | | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | | 主引用文献 | Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
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7SYR
 | | Structure of the wt IRES eIF2-containing 48S initiation complex, closed conformation. Structure 12(wt). | | 分子名称: | 18S rRNA, Eukaryotic translation initiation factor 1A, X-chromosomal, ... | | 著者 | Brown, Z.P, Abaeva, I.S, De, S, Hellen, C.U.T, Pestova, T.V, Frank, J. | | 登録日 | 2021-11-25 | | 公開日 | 2022-07-27 | | 最終更新日 | 2022-08-24 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Molecular architecture of 40S translation initiation complexes on the hepatitis C virus IRES.
Embo J., 41, 2022
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7SP0
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3W97
 | | Crystal Structure of Human Nucleosome Core Particle lacking H2B N-terminal region | | 分子名称: | 146-mer DNA, Histone H2A type 1-B/E, Histone H2B type 1-J, ... | | 著者 | Iwasaki, W, Miya, Y, Horikoshi, N, Osakabe, A, Tachiwana, H, Shibata, T, Kagawa, W, Kurumizaka, H. | | 登録日 | 2013-04-01 | | 公開日 | 2013-08-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Contribution of histone N-terminal tails to the structure and stability of nucleosomes
FEBS Open Bio, 3, 2013
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5MRG
 | | Solution structure of TDP-43 (residues 1-102) | | 分子名称: | TAR DNA-binding protein 43 | | 著者 | Mompean, M, Romano, V, Pantoja-Uceda, D, Stuani, C, Baralle, F.E, Laurents, D.V. | | 登録日 | 2016-12-22 | | 公開日 | 2017-06-07 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Point mutations in the N-terminal domain of transactive response DNA-binding protein 43 kDa (TDP-43) compromise its stability, dimerization, and functions.
J. Biol. Chem., 292, 2017
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7SCY
 | | Nuc147 bound to single BRCT | | 分子名称: | DNA (147-MER), Histone H2A, Histone H2B type 1-J, ... | | 著者 | Muthurajan, U.M, Rudolph, J.R. | | 登録日 | 2021-09-29 | | 公開日 | 2022-01-12 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | The BRCT domain of PARP1 binds intact DNA and mediates intrastrand transfer.
Mol.Cell, 81, 2021
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7SCZ
 | | Nuc147 bound to multiple BRCTs | | 分子名称: | DNA (147-MER), Histone H2A, Histone H2B type 1-J, ... | | 著者 | Muthurajan, U.M, Rudolph, J. | | 登録日 | 2021-09-29 | | 公開日 | 2022-01-19 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | The BRCT domain of PARP1 binds intact DNA and mediates intrastrand transfer.
Mol.Cell, 81, 2021
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7TOR
 | | Mammalian 80S ribosome bound with the ALS/FTD-associated dipeptide repeat protein GR20 | | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | | 著者 | Loveland, A.B, Svidritskiy, E, Susorov, D, Lee, S, Park, A, Zvornicanin, S, Demo, G, Gao, F.B, Korostelev, A.A. | | 登録日 | 2022-01-24 | | 公開日 | 2022-05-25 | | 最終更新日 | 2022-06-01 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM.
Nat Commun, 13, 2022
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3V5B
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7U51
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7U50
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7U52
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7U53
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7TUJ
 | | NMR solution structure of the phosphorylated MUS81-binding region from human SLX4 | | 分子名称: | Structure-specific endonuclease subunit SLX4 | | 著者 | Payliss, B.J, Reichheld, S.E, Lemak, A, Arrowsmith, C.H, Sharpe, S, Wyatt, H.D.M. | | 登録日 | 2022-02-02 | | 公開日 | 2022-10-19 | | 最終更新日 | 2022-11-09 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Phosphorylation of the DNA repair scaffold SLX4 drives folding of the SAP domain and activation of the MUS81-EME1 endonuclease.
Cell Rep, 41, 2022
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3UVX
 | | Crystal Structure of the first bromodomain of human BRD4 in complex with a diacetylated histone 4 peptide (H4K12acK16ac) | | 分子名称: | 1,2-ETHANEDIOL, Bromodomain-containing protein 4, FORMIC ACID, ... | | 著者 | Filippakopoulos, P, Picaud, S, Keates, T, Ugochukwu, E, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2011-11-30 | | 公開日 | 2012-01-25 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | | 主引用文献 | Histone recognition and large-scale structural analysis of the human bromodomain family.
Cell(Cambridge,Mass.), 149, 2012
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2CUF
 | | Solution structure of the homeobox domain of the human hypothetical protein FLJ21616 | | 分子名称: | FLJ21616 protein | | 著者 | Ohnishi, S, Kigawa, T, Tomizawa, T, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2005-05-26 | | 公開日 | 2005-11-26 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the homeobox domain of the human hypothetical protein FLJ21616
To be Published
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3X1U
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2CV5
 | | Crystal structure of human nucleosome core particle | | 分子名称: | CHLORIDE ION, DNA (146-MER), Histone H2A.a, ... | | 著者 | Tsunaka, Y, Kajimura, N, Tate, S, Morikawa, K. | | 登録日 | 2005-05-31 | | 公開日 | 2005-06-28 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Alteration of the nucleosomal DNA path in the crystal structure of a human nucleosome core particle
Nucleic Acids Res., 33, 2005
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