Loading
PDBj
メニューPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help

9J8M
DownloadVisualize
BU of 9j8m by Molmil
Cryo-EM structure of BAF-Lamin A/C IgF-nucleosome complex (High mobility complex)
分子名称: Barrier-to-autointegration factor, DNA (193-MER), Histone H2A type 1-B/E, ...
著者Horikoshi, N, Miyake, R, Sogawa-Fujiwara, C, Ogasawara, M, Takizawa, Y, Kurumizaka, H.
登録日2024-08-21
公開日2025-02-26
最終更新日2025-07-02
実験手法ELECTRON MICROSCOPY (3.82 Å)
主引用文献Cryo-EM structures of the BAF-Lamin A/C complex bound to nucleosomes.
Nat Commun, 16, 2025
1YVZ
DownloadVisualize
BU of 1yvz by Molmil
Hepatitis C Virus RNA Polymerase Genotype 2a In Complex With Non- Nucleoside Analogue Inhibitor
分子名称: 3-[(2,4-DICHLOROBENZOYL)(ISOPROPYL)AMINO]-5-PHENYLTHIOPHENE-2-CARBOXYLIC ACID, RNA dependent RNA polymerase, SULFATE ION
著者Biswal, B.K, Cherney, M.M, Wang, M, Chan, L, Yannopoulos, C.G, Bilimoria, D, Nicolas, O, Bedard, J, James, M.N.G.
登録日2005-02-16
公開日2005-03-22
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structures of the RNA dependent RNA polymerase genotype 2a of hepatitis C virus reveal two conformations and suggest mechanisms of inhibition by non-nucleoside inhibitors.
J.Biol.Chem., 280, 2005
1YBF
DownloadVisualize
BU of 1ybf by Molmil
Crystal structure of AMP nucleosidase from Bacteroides thetaiotaomicron VPI-5482
分子名称: AMP nucleosidase
著者Krishnamurthy, N.R, Swaminathan, S, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2004-12-20
公開日2005-01-04
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of AMP nucleosidase from Bacteroides thetaiotaomicron
To be published
3K8O
DownloadVisualize
BU of 3k8o by Molmil
Crystal structure of human purine nucleoside phosphorylase in complex with DATMe-ImmH
分子名称: 7-({[(1R,2S)-2,3-DIHYDROXY-1-(HYDROXYMETHYL)PROPYL]AMINO}METHYL)-3,5-DIHYDRO-4H-PYRROLO[3,2-D]PYRIMIDIN-4-ONE, Purine nucleoside phosphorylase, SULFATE ION
著者Ho, M, Rinaldo-matthis, A, Almo, S.C, Schramm, V.L.
登録日2009-10-14
公開日2010-03-02
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of human purine nucleoside phosphorylase in complex with DATMe-Immucillin H
Proc.Natl.Acad.Sci.USA, 2010
8HXZ
DownloadVisualize
BU of 8hxz by Molmil
Cryo-EM structure of Eaf3 CHD in complex with nucleosome
分子名称: Chromatin modification-related protein EAF3, DNA (352-MER), Histone H2A, ...
著者Cui, H, Wang, H.
登録日2023-01-05
公開日2023-09-27
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structure of histone deacetylase complex Rpd3S bound to nucleosome.
Nat.Struct.Mol.Biol., 30, 2023
7Y8R
DownloadVisualize
BU of 7y8r by Molmil
The nucleosome-bound human PBAF complex
分子名称: ACTB protein (Fragment), ADENOSINE-5'-DIPHOSPHATE, AT-rich interactive domain-containing protein 2, ...
著者Wang, L, Yu, J, Yu, Z, Wang, Q, He, S, Xu, Y.
登録日2022-06-24
公開日2022-12-07
最終更新日2024-07-03
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Structure of nucleosome-bound human PBAF complex.
Nat Commun, 13, 2022
1KFD
DownloadVisualize
BU of 1kfd by Molmil
CRYSTAL STRUCTURES OF THE KLENOW FRAGMENT OF DNA POLYMERASE I COMPLEXED WITH DEOXYNUCLEOSIDE TRIPHOSPHATE AND PYROPHOSPHATE
分子名称: CYTIDINE-5'-TRIPHOSPHATE, DNA POLYMERASE I KLENOW FRAGMENT
著者Beese, L.S, Friedman, J.M, Steitz, T.A.
登録日1993-09-23
公開日1994-06-22
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献Crystal structures of the Klenow fragment of DNA polymerase I complexed with deoxynucleoside triphosphate and pyrophosphate.
Biochemistry, 32, 1993
9L5T
DownloadVisualize
BU of 9l5t by Molmil
Cryo-EM structure of the thermophile spliceosome (state B*Q2)
分子名称: Anaphase-promoting complex subunit 4-like WD40 domain-containing protein, CCDC12, Delta(14)-sterol reductase, ...
著者Li, Y, Fischer, P, Wang, M, Yuan, R, Meng, W, Luehrmann, R, Lau, B, Hurt, E, Cheng, J.
登録日2024-12-23
公開日2025-03-12
最終更新日2025-04-16
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural insights into spliceosome fidelity: DHX35-GPATCH1- mediated rejection of aberrant splicing substrates.
Cell Res., 35, 2025
9L5S
DownloadVisualize
BU of 9l5s by Molmil
Cryo-EM structure of the thermophile spliceosome (state B*Q1)
分子名称: Anaphase-promoting complex subunit 4-like WD40 domain-containing protein, CCDC12, Delta(14)-sterol reductase, ...
著者Li, Y, Fischer, P, Wang, M, Yuan, R, Meng, W, Luehrmann, R, Lau, B, Hurt, E, Cheng, J.
登録日2024-12-23
公開日2025-03-12
最終更新日2025-04-16
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural insights into spliceosome fidelity: DHX35-GPATCH1- mediated rejection of aberrant splicing substrates.
Cell Res., 35, 2025
9L5R
DownloadVisualize
BU of 9l5r by Molmil
Cryo-EM structure of the thermophile spliceosome (state ILS)
分子名称: Anaphase-promoting complex subunit 4-like WD40 domain-containing protein, CCDC12, Cell cycle control protein, ...
著者Li, Y, Fischer, P, Wang, M, Yuan, R, Meng, W, Luehrmann, R, Lau, B, Hurt, E, Cheng, J.
登録日2024-12-23
公開日2025-03-12
最終更新日2025-04-16
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structural insights into spliceosome fidelity: DHX35-GPATCH1- mediated rejection of aberrant splicing substrates.
Cell Res., 35, 2025
9B3P
DownloadVisualize
BU of 9b3p by Molmil
The cryo-EM structure of the H2A.Z-H3.3 double-variant nucleosome
分子名称: DNA (128-MER), Histone H2A.Z, Histone H2B 1.1, ...
著者Tan, D, Sokolova, V.
登録日2024-03-19
公開日2024-06-12
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural and Biochemical Characterization of the Nucleosome Containing Variants H3.3 and H2A.Z.
Epigenomes, 8, 2024
8V6V
DownloadVisualize
BU of 8v6v by Molmil
Cryo-EM structure of doubly-bound SNF2h-nucleosome complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, Histone H2A type 1, Histone H2B, ...
著者Chio, U.S, Palovcak, E, Armache, J.P, Narlikar, G.J, Cheng, Y.
登録日2023-12-03
公開日2024-03-20
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Functionalized graphene-oxide grids enable high-resolution cryo-EM structures of the SNF2h-nucleosome complex without crosslinking.
Nat Commun, 15, 2024
8V4Y
DownloadVisualize
BU of 8v4y by Molmil
Cryo-EM structure of singly-bound SNF2h-nucleosome complex with SNF2h at inactive SHL2 (conformation 1)
分子名称: ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, Histone H2A type 1, ...
著者Chio, U.S, Palovcak, E, Armache, J.P, Narlikar, G.J, Cheng, Y.
登録日2023-11-29
公開日2024-03-20
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Functionalized graphene-oxide grids enable high-resolution cryo-EM structures of the SNF2h-nucleosome complex without crosslinking.
Nat Commun, 15, 2024
8VFY
DownloadVisualize
BU of 8vfy by Molmil
Cryo-EM structure of FoxA1 in complex with ALBN1 nucleosome (class 1)
分子名称: DNA (171-MER), Hepatocyte nuclear factor 3-alpha, Histone H2A type 1-B/E, ...
著者Zhou, B.R, Bai, Y.
登録日2023-12-22
公開日2024-08-07
最終更新日2025-05-21
実験手法ELECTRON MICROSCOPY (2.89 Å)
主引用文献Structural insights into the cooperative nucleosome recognition and chromatin opening by FOXA1 and GATA4.
Mol.Cell, 84, 2024
8VG1
DownloadVisualize
BU of 8vg1 by Molmil
Cryo-EM structure of FoxA1 and GATA4 in complex with ALBN1 nucleosome
分子名称: DNA (171-MER), Hepatocyte nuclear factor 3-alpha, Histone H2A type 1-B/E, ...
著者Zhou, B.R, Bai, Y.
登録日2023-12-22
公開日2024-08-07
最終更新日2025-05-28
実験手法ELECTRON MICROSCOPY (2.48 Å)
主引用文献Structural insights into the cooperative nucleosome recognition and chromatin opening by FOXA1 and GATA4.
Mol.Cell, 84, 2024
8VFZ
DownloadVisualize
BU of 8vfz by Molmil
Cryo-EM structure of FoxA1 in complex with ALBN1 nucleosome (class 2)
分子名称: DNA (171-MER), Hepatocyte nuclear factor 3-alpha, Histone H2A type 1-B/E, ...
著者Zhou, B.R, Bai, Y.
登録日2023-12-22
公開日2024-08-07
最終更新日2025-05-14
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structural insights into the cooperative nucleosome recognition and chromatin opening by FOXA1 and GATA4.
Mol.Cell, 84, 2024
1QE5
DownloadVisualize
BU of 1qe5 by Molmil
PURINE NUCLEOSIDE PHOSPHORYLASE FROM CELLULOMONAS SP. IN COMPLEX WITH PHOSPHATE
分子名称: CALCIUM ION, PENTOSYLTRANSFERASE, PHOSPHATE ION
著者Tebbe, J, Bzowska, A, Wielgus-Kutrowska, B, Schroeder, W, Kazimierczuk, Z, Shugar, D, Saenger, W, Koellner, G.
登録日1999-07-13
公開日1999-12-12
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of the purine nucleoside phosphorylase (PNP) from Cellulomonas sp. and its implication for the mechanism of trimeric PNPs.
J.Mol.Biol., 294, 1999
6JM9
DownloadVisualize
BU of 6jm9 by Molmil
cryo-EM structure of DOT1L bound to unmodified nucleosome
分子名称: DNA strand I, DNA strand J, Histone H2A, ...
著者Jang, S, Song, J.J.
登録日2019-03-07
公開日2019-05-15
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (7.3 Å)
主引用文献Structural basis of recognition and destabilization of the histone H2B ubiquitinated nucleosome by the DOT1L histone H3 Lys79 methyltransferase.
Genes Dev., 33, 2019
8YBK
DownloadVisualize
BU of 8ybk by Molmil
Cryo-EM structure of the human nucleosome containing the H3.1 E97K mutant
分子名称: DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Kimura, T, Hirai, S, Kujirai, T, Ogasawara, M, Takizawa, Y, Kurumizaka, H.
登録日2024-02-14
公開日2024-07-24
最終更新日2024-09-11
実験手法ELECTRON MICROSCOPY (2.69 Å)
主引用文献Cryo-EM structure and biochemical analyses of the nucleosome containing the cancer-associated histone H3 mutation E97K.
Genes Cells, 29, 2024
3H59
DownloadVisualize
BU of 3h59 by Molmil
Hepatitis C virus polymerase NS5B with thiazine inhibitor 2
分子名称: N-{3-[(5S)-5-(1,1-dimethylpropyl)-1-(4-fluoro-3-methylbenzyl)-4-hydroxy-2-oxo-2,5-dihydro-1H-pyrrol-3-yl]-1,1-dioxido-4H-1,4-benzothiazin-7-yl}methanesulfonamide, RNA-directed RNA polymerase
著者Harris, S.F, Ghate, M.
登録日2009-04-21
公開日2009-09-08
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Non-nucleoside inhibitors of HCV polymerase NS5B. Part 3: synthesis and optimization studies of benzothiazine-substituted tetramic acids
Bioorg.Med.Chem.Lett., 19, 2009
3NM6
DownloadVisualize
BU of 3nm6 by Molmil
Helicobacter pylori MTAN complexed with adenine and tris
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENINE, ...
著者Ronning, D.R, Iacopelli, N.M.
登録日2010-06-21
公開日2010-11-24
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.602 Å)
主引用文献Enzyme-ligand interactions that drive active site rearrangements in the Helicobacter pylori 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase.
Protein Sci., 19, 2010
3NM5
DownloadVisualize
BU of 3nm5 by Molmil
Helicobacter pylori MTAN complexed with Formycin A
分子名称: (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol, MTA/SAH nucleosidase
著者Ronning, D.R, Iacopelli, N.M.
登録日2010-06-21
公開日2010-11-24
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Enzyme-ligand interactions that drive active site rearrangements in the Helicobacter pylori 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase.
Protein Sci., 19, 2010
6KE9
DownloadVisualize
BU of 6ke9 by Molmil
The Human Telomeric Nucleosome Displays Distinct Structural and Dynamic Properties
分子名称: Histone H2A type 1-B/E, Histone H2B type 1-K, Histone H3.1, ...
著者Soman, A, Liew, C.W, Teo, H.L, Berezhnoy, N, Korolev, N, Rhodes, D, Nordenskiold, L.
登録日2019-07-04
公開日2020-04-22
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献The human telomeric nucleosome displays distinct structural and dynamic properties.
Nucleic Acids Res., 48, 2020
3NM4
DownloadVisualize
BU of 3nm4 by Molmil
Helicobacter pylori MTAN
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MTA/SAH nucleosidase
著者Ronning, D.R, Iacopelli, N.M.
登録日2010-06-21
公開日2010-11-24
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Enzyme-ligand interactions that drive active site rearrangements in the Helicobacter pylori 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase.
Protein Sci., 19, 2010
3K8Q
DownloadVisualize
BU of 3k8q by Molmil
Crystal structure of human purine nucleoside phosphorylase in complex with SerMe-Immucillin H
分子名称: 7-({[2-hydroxy-1-(hydroxymethyl)ethyl]amino}methyl)-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one, PHOSPHATE ION, Purine nucleoside phosphorylase
著者Ho, M, Almo, S.C, Scharmm, V.L.
登録日2009-10-14
公開日2010-03-02
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structure of human nucleoside phosphorylase in complex with SerMe-ImmH
Proc.Natl.Acad.Sci.USA, 2010

238582

件を2025-07-09に公開中

PDB statisticsPDBj update infoContact PDBjnumon