2PU4
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2PU2
| AmpC beta-lactamase with bound Phthalamide inhibitor | 分子名称: | 2-[(1R)-1-CARBOXY-2-(4-HYDROXYPHENYL)ETHYL]-1,3-DIOXOISOINDOLINE-5-CARBOXYLIC ACID, Beta-lactamase, PHOSPHATE ION | 著者 | Babaoglu, K, Shoichet, B.K. | 登録日 | 2007-05-08 | 公開日 | 2008-04-15 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Comprehensive mechanistic analysis of hits from high-throughput and docking screens against beta-lactamase. J.Med.Chem., 51, 2008
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2P9V
| Structure of AmpC beta-lactamase with cross-linked active site after exposure to small molecule inhibitor | 分子名称: | Beta-lactamase, PHOSPHATE ION | 著者 | Babaoglu, K, Wyrembak, P.N, Pelto, R.B, Shoichet, B.K, Pratt, R.F. | 登録日 | 2007-03-26 | 公開日 | 2007-08-14 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | O-Aryloxycarbonyl Hydroxamates: New beta-Lactamase Inhibitors That Cross-Link the Active Site. J.Am.Chem.Soc., 129, 2007
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2P74
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2OV5
| Crystal structure of the KPC-2 carbapenemase | 分子名称: | BICINE, Carbapenemase | 著者 | Ke, W, Bethel, C.R, Thomson, J.M, Bonomo, R.A, van den Akker, F. | 登録日 | 2007-02-13 | 公開日 | 2007-05-01 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Crystal Structure of KPC-2: Insights into Carbapenemase Activity in Class A beta-Lactamases. Biochemistry, 46, 2007
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2I72
| AmpC beta-lactamase in complex with 5-diformylaminomethyl-benzo[b]thiophen-2-boronic acid | 分子名称: | Beta-lactamase, {5-[(DIFORMYLAMINO)METHYL]-1-BENZOTHIEN-2-YL}BORONIC ACID | 著者 | Venturelli, A, Cancian, L, Tondi, D, Morandi, F, Cannazza, G, Segatore, B, Prati, F, Amicosante, G, Shoichet, B.K, Costi, M.P. | 登録日 | 2006-08-30 | 公開日 | 2007-09-11 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Optimizing Cell Permeation of an Antibiotic Resistance Inhibitor for Improved Efficacy J.Med.Chem., 50, 2007
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2HDU
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2HDS
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2HDR
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2HDQ
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2H5S
| SA2-13 penam sulfone complexed to wt SHV-1 beta-lactamase | 分子名称: | (3R)-4-[(4-CARBOXYBUTANOYL)OXY]-N-[(1E)-3-OXOPROP-1-EN-1-YL]-3-SULFINO-D-VALINE, CYCLOHEXYL-HEXYL-BETA-D-MALTOSIDE, SHV-1 beta-lactamase | 著者 | van den Akker, F, Padayatti, P.S. | 登録日 | 2006-05-27 | 公開日 | 2006-10-17 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.28 Å) | 主引用文献 | Rational Design of a beta-Lactamase Inhibitor Achieved via Stabilization of the trans-Enamine Intermediate: 1.28 A Crystal Structure of wt SHV-1 Complex with a Penam Sulfone. J.Am.Chem.Soc., 128, 2006
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2H10
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2H0Y
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2H0T
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2GDN
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2G2W
| Crystal Structure of the SHV D104K Beta-lactamase/Beta-lactamase inhibitor protein (BLIP) complex | 分子名称: | Beta-lactamase SHV-1, Beta-lactamase inhibitory protein | 著者 | Reynolds, K.A, Thomson, J.M, Corbett, K.D, Bethel, C.R, Berger, J.M, Kirsch, J.F, Bonomo, R.A, Handel, T.M. | 登録日 | 2006-02-16 | 公開日 | 2006-07-04 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural and Computational Characterization of the SHV-1 beta-Lactamase-beta-Lactamase Inhibitor Protein Interface. J.Biol.Chem., 281, 2006
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2G2U
| Crystal Structure of the SHV-1 Beta-lactamase/Beta-lactamase inhibitor protein (BLIP) complex | 分子名称: | Beta-lactamase SHV-1, Beta-lactamase inhibitory protein | 著者 | Reynolds, K.A, Thomson, J.M, Corbett, K.D, Bethel, C.R, Berger, J.M, Kirsch, J.F, Bonomo, R.A, Handel, T.M. | 登録日 | 2006-02-16 | 公開日 | 2006-07-04 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural and Computational Characterization of the SHV-1 beta-Lactamase-beta-Lactamase Inhibitor Protein Interface. J.Biol.Chem., 281, 2006
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2FFY
| AmpC beta-lactamase N289A mutant in complex with a boronic acid deacylation transition state analog compound SM3 | 分子名称: | (1R)-1-(2-THIENYLACETYLAMINO)-1-PHENYLMETHYLBORONIC ACID, Beta-lactamase, PHOSPHATE ION, ... | 著者 | Chen, Y, Minasov, G, Roth, T.A, Prati, F, Shoichet, B.K. | 登録日 | 2005-12-20 | 公開日 | 2006-03-28 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.07 Å) | 主引用文献 | The deacylation mechanism of AmpC beta-lactamase at ultrahigh resolution J.Am.Chem.Soc., 128, 2006
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2EFX
| The crystal structure of D-amino acid amidase from Ochrobactrum anthropi SV3 complexed with L-phenylalanine amide | 分子名称: | BARIUM ION, D-amino acid amidase, PHENYLALANINE AMIDE | 著者 | Okazaki, S, Suzuki, A, Mizushima, T, Komeda, H, Asano, Y, Yamane, T. | 登録日 | 2007-02-26 | 公開日 | 2007-03-06 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structures of D-amino-acid amidase complexed with L-phenylalanine and with L-phenylalanine amide: insight into the D-stereospecificity of D-amino-acid amidase from Ochrobactrum anthropi SV3. Acta Crystallogr.,Sect.D, 64, 2008
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2EFU
| The crystal structure of D-amino acid amidase from Ochrobactrum anthropi SV3 complexed with L-phenylalanine | 分子名称: | BARIUM ION, D-Amino acid amidase, PHENYLALANINE | 著者 | Okazaki, S, Suzuki, A, Mizushima, T, Komeda, H, Asano, Y, Yamane, T. | 登録日 | 2007-02-26 | 公開日 | 2007-03-06 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structures of D-amino-acid amidase complexed with L-phenylalanine and with L-phenylalanine amide: insight into the D-stereospecificity of D-amino-acid amidase from Ochrobactrum anthropi SV3. Acta Crystallogr.,Sect.D, 64, 2008
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2E8I
| Structure of 6-aminohexanoate-dimer hydrolase, D1 mutant | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-aminohexanoate-dimer hydrolase, GLYCEROL, ... | 著者 | Shibata, N, Higuchi, Y, Negoro, S. | 登録日 | 2007-01-20 | 公開日 | 2008-01-15 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Molecular design of a nylon-6 byproduct-degrading enzyme from a carboxylesterase with a beta-lactamase fold. Febs J., 276, 2009
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2DRW
| The crystal structutre of D-amino acid amidase from Ochrobactrum anthropi SV3 | 分子名称: | BARIUM ION, D-Amino acid amidase | 著者 | Okazaki, S, Suzuki, A, Komeda, H, Asano, Y, Yamane, T. | 登録日 | 2006-06-15 | 公開日 | 2006-07-04 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal Structure and Functional Characterization of a D-Stereospecific Amino Acid Amidase from Ochrobactrum anthropi SV3, a New Member of the Penicillin-recognizing Proteins J.Mol.Biol., 368, 2007
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2DNS
| The crystal structure of D-amino acid amidase from Ochrobactrum anthropi SV3 complexed with D-Phenylalanine | 分子名称: | BARIUM ION, D-PHENYLALANINE, D-amino acid amidase | 著者 | Okazaki, S, Suzuki, A, Komeda, H, Asano, Y, Yamane, T. | 登録日 | 2006-04-26 | 公開日 | 2006-05-09 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal Structure and Functional Characterization of a D-Stereospecific Amino Acid Amidase from Ochrobactrum anthropi SV3, a New Member of the Penicillin-recognizing Proteins J.Mol.Biol., 368, 2007
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2DCF
| Crystal structure of 6-aminohexanoate-dimer hydrolase S112A/G181D/H266N mutant with substrate | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 6-AMINOHEXANOIC ACID, 6-aminohexanoate-dimer hydrolase, ... | 著者 | Ohki, T, Shibata, N, Higuchi, Y, Takeo, M, Negoro, S. | 登録日 | 2006-01-06 | 公開日 | 2007-01-09 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Nylon-oligomer degrading enzyme/substrate complex: catalytic mechanism of 6-aminohexanoate-dimer hydrolase J.Mol.Biol., 370, 2007
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2CC1
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