2P9V
Structure of AmpC beta-lactamase with cross-linked active site after exposure to small molecule inhibitor
Summary for 2P9V
Entry DOI | 10.2210/pdb2p9v/pdb |
Descriptor | Beta-lactamase, PHOSPHATE ION, ... (4 entities in total) |
Functional Keywords | beta-lactamase, cross-link, hydrolase |
Biological source | Escherichia coli More |
Cellular location | Periplasm: P00811 P00811 |
Total number of polymer chains | 2 |
Total formula weight | 79313.82 |
Authors | Babaoglu, K.,Wyrembak, P.N.,Pelto, R.B.,Shoichet, B.K.,Pratt, R.F. (deposition date: 2007-03-26, release date: 2007-08-14, Last modification date: 2011-07-13) |
Primary citation | Wyrembak, P.N.,Babaoglu, K.,Pelto, R.B.,Shoichet, B.K.,Pratt, R.F. O-Aryloxycarbonyl Hydroxamates: New beta-Lactamase Inhibitors That Cross-Link the Active Site. J.Am.Chem.Soc., 129:9548-9549, 2007 Cited by PubMed: 17628063DOI: 10.1021/ja072370u PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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