7QI3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7qi3 by Molmil](/molmil-images/mine/7qi3) | Structure of Fusarium verticillioides NAT1 (FDB2) N-malonyltransferase | 分子名称: | 1,2-ETHANEDIOL, Arylamine N-acetyltransferase, DI(HYDROXYETHYL)ETHER, ... | 著者 | Lowe, E.D, Kotomina, E, Karagianni, E, Boukouvala, S. | 登録日 | 2021-12-14 | 公開日 | 2022-11-23 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Fusarium verticillioides NAT1 (FDB2) N-malonyltransferase is structurally, functionally and phylogenetically distinct from its N-acetyltransferase (NAT) homologues. Febs J., 290, 2023
|
|
8FY2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fy2 by Molmil](/molmil-images/mine/8fy2) | E3:PROTAC:target ternary complex structure (VCB/WH244/BCL-2) | 分子名称: | Apoptosis regulator Bcl-2, Elongin-B, Elongin-C, ... | 著者 | Nayak, D, Lv, D, Yuan, Y, Zhang, P, Hu, W, Ruben, E, Lv, Z, Sung, P, Hromas, R, Zheng, G, Zhou, D, Olsen, S.K. | 登録日 | 2023-01-25 | 公開日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (2.98 Å) | 主引用文献 | Development and crystal structures of a potent second-generation dual degrader of BCL-2 and BCL-xL. Nat Commun, 15, 2024
|
|
8FY0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fy0 by Molmil](/molmil-images/mine/8fy0) | E3:PROTAC:target ternary complex structure (VCB/753b/BCL-xL) | 分子名称: | Bcl-2-like protein 1, CACODYLIC ACID, Elongin-B, ... | 著者 | Olsen, S.K, Nayak, D, Lv, D, Yuan, Y, Zhang, P, Hu, W, Lv, Z, Sung, P, Hromas, R, Zheng, G, Zhou, D. | 登録日 | 2023-01-25 | 公開日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (2.94 Å) | 主引用文献 | Development and crystal structures of a potent second-generation dual degrader of BCL-2 and BCL-xL. Nat Commun, 15, 2024
|
|
8FY1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8fy1 by Molmil](/molmil-images/mine/8fy1) | E3:PROTAC:target ternary complex structure (VCB/753b/BCL-2) | 分子名称: | Apoptosis regulator Bcl-2, Elongin-B, Elongin-C, ... | 著者 | Nayak, D, Lv, D, Yuan, Y, Zhang, P, Hu, W, Lv, Z, Sung, P, Hromas, R, Zheng, G, Zhou, D, Olsen, S.K. | 登録日 | 2023-01-25 | 公開日 | 2024-04-10 | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | 主引用文献 | Development and crystal structures of a potent second-generation dual degrader of BCL-2 and BCL-xL. Nat Commun, 15, 2024
|
|
4YGX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ygx by Molmil](/molmil-images/mine/4ygx) | |
6LTR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ltr by Molmil](/molmil-images/mine/6ltr) | Crystal structure of Cas12i2 ternary complex with single Mg2+ bound in catalytic pocket | 分子名称: | 1,2-ETHANEDIOL, Cas12i2, DNA (35-MER), ... | 著者 | Huang, X, Sun, W, Cheng, Z, Chen, M, Li, X, Wang, J, Sheng, G, Gong, W, Wang, Y. | 登録日 | 2020-01-23 | 公開日 | 2020-10-28 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | 主引用文献 | Structural basis for two metal-ion catalysis of DNA cleavage by Cas12i2. Nat Commun, 11, 2020
|
|
6LU0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6lu0 by Molmil](/molmil-images/mine/6lu0) | Crystal structure of Cas12i2 ternary complex with 12 nt spacer | 分子名称: | Cas12i2, DNA (5'-D(*GP*CP*CP*GP*CP*TP*TP*TP*CP*TP*T)-3'), DNA (5'-D(*GP*CP*TP*TP*GP*CP*TP*CP*TP*GP*TP*TP*GP*AP*AP*AP*GP*CP*GP*GP*C)-3'), ... | 著者 | Huang, X, Sun, W, Cheng, Z, Chen, M, Li, X, Wang, J, Sheng, G, Gong, W, Wang, Y. | 登録日 | 2020-01-24 | 公開日 | 2020-10-28 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.22 Å) | 主引用文献 | Structural basis for two metal-ion catalysis of DNA cleavage by Cas12i2. Nat Commun, 11, 2020
|
|
4B6U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4b6u by Molmil](/molmil-images/mine/4b6u) | Solution structure of eIF4E3 in complex with m7GDP | 分子名称: | 7N-METHYL-8-HYDROGUANOSINE-5'-DIPHOSPHATE, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TYPE 3 | 著者 | Osborne, M.J, Volpon, L, Kornblatt, J.A, Culkjovic-Kraljcic, B, Baguet, A, Borden, K.L.B. | 登録日 | 2012-08-15 | 公開日 | 2013-03-06 | 最終更新日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | Eif4E3 Acts as a Tumor Suppressor by Utilizing an Atypical Mode of Methyl-7-Guanosine CAP Recognition Proc.Natl.Acad.Sci.USA, 110, 2013
|
|
6LTP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ltp by Molmil](/molmil-images/mine/6ltp) | Crystal structure of Cas12i2 binary complex | 分子名称: | Cas12i2, crRNA (56-mer RNA) | 著者 | Huang, X, Sun, W, Cheng, Z, Chen, M, Li, X, Wang, J, Sheng, G, Gong, W, Wang, Y. | 登録日 | 2020-01-23 | 公開日 | 2020-10-28 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Structural basis for two metal-ion catalysis of DNA cleavage by Cas12i2. Nat Commun, 11, 2020
|
|
5UTF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5utf by Molmil](/molmil-images/mine/5utf) | Crystal Structure of a Stabilized DS-SOSIP.6mut BG505 gp140 HIV-1 Env Trimer, Containing Mutations I201C-P433C (DS), L154M, Y177W, N300M, N302M, T320L, I420M in Complex with Human Antibodies PGT122 and 35O22 at 4.3 A | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35022 Heavy chain, ... | 著者 | Pancera, M, Chuang, G.-Y, Xu, K, Kwong, P.D. | 登録日 | 2017-02-14 | 公開日 | 2017-03-29 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.503 Å) | 主引用文献 | Structure-Based Design of a Soluble Prefusion-Closed HIV-1 Env Trimer with Reduced CD4 Affinity and Improved Immunogenicity. J. Virol., 91, 2017
|
|
6LTU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6ltu by Molmil](/molmil-images/mine/6ltu) | Crystal structure of Cas12i2 ternary complex with double Mg2+ bound in catalytic pocket | 分子名称: | 1,2-ETHANEDIOL, Cas12i2, DNA (35-MER), ... | 著者 | Huang, X, Sun, W, Cheng, Z, Chen, M, Li, X, Wang, J, Sheng, G, Gong, W, Wang, Y. | 登録日 | 2020-01-23 | 公開日 | 2020-10-28 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.57 Å) | 主引用文献 | Structural basis for two metal-ion catalysis of DNA cleavage by Cas12i2. Nat Commun, 11, 2020
|
|
3NJ0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3nj0 by Molmil](/molmil-images/mine/3nj0) | X-ray crystal structure of the PYL2-pyrabactin A complex | 分子名称: | 4-bromo-N-(pyridin-2-ylmethyl)naphthalene-1-sulfonamide, Abscisic acid receptor PYL2, DI(HYDROXYETHYL)ETHER, ... | 著者 | Peterson, F.C, Burgie, E.S, Bingman, C.A, Volkman, B.F, Phillips Jr, G.N, Cutler, S.R, Jensen, D.R, Center for Eukaryotic Structural Genomics (CESG) | 登録日 | 2010-06-16 | 公開日 | 2010-08-18 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Structural basis for selective activation of ABA receptors. Nat.Struct.Mol.Biol., 17, 2010
|
|
5ANR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5anr by Molmil](/molmil-images/mine/5anr) | Structure of a human 4E-T - DDX6 - CNOT1 complex | 分子名称: | CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E TRANSPORTER, PROBABLE ATP-DEPENDENT RNA HELICASE DDX6 | 著者 | Basquin, J, Oezguer, S, Conti, E. | 登録日 | 2015-09-08 | 公開日 | 2015-10-21 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.102 Å) | 主引用文献 | Structure of a Human 4E-T/Ddx6/Cnot1 Complex Reveals the Different Interplay of Ddx6-Binding Proteins with the Ccr4-not Complex. Cell Rep., 13, 2015
|
|
3NJO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3njo by Molmil](/molmil-images/mine/3njo) | X-ray crystal structure of the Pyr1-pyrabactin A complex | 分子名称: | 4-bromo-N-(pyridin-2-ylmethyl)naphthalene-1-sulfonamide, Abscisic acid receptor PYR1, CHLORIDE ION, ... | 著者 | Burgie, E.S, Bingman, C.A, Phillips Jr, G.N, Peterson, F.C, Volkman, B.F, Cutler, S.R, Jensen, D.R, Center for Eukaryotic Structural Genomics (CESG) | 登録日 | 2010-06-17 | 公開日 | 2010-08-18 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.473 Å) | 主引用文献 | Structural basis for selective activation of ABA receptors. Nat.Struct.Mol.Biol., 17, 2010
|
|
3NJ1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3nj1 by Molmil](/molmil-images/mine/3nj1) | X-ray crystal structure of the PYL2(V114I)-pyrabactin A complex | 分子名称: | 4-bromo-N-(pyridin-2-ylmethyl)naphthalene-1-sulfonamide, Abscisic acid receptor PYL2, GLYCEROL, ... | 著者 | Peterson, F.C, Burgie, E.S, Bingman, C.A, Volkman, B.F, Phillips Jr, G.N, Cutler, S.R, Jensen, D.R, Center for Eukaryotic Structural Genomics (CESG) | 登録日 | 2010-06-16 | 公開日 | 2010-08-18 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.948 Å) | 主引用文献 | Structural basis for selective activation of ABA receptors. Nat.Struct.Mol.Biol., 17, 2010
|
|
1LIN
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1lin by Molmil](/molmil-images/mine/1lin) | CALMODULIN COMPLEXED WITH TRIFLUOPERAZINE (1:4 COMPLEX) | 分子名称: | 10-[3-(4-METHYL-PIPERAZIN-1-YL)-PROPYL]-2-TRIFLUOROMETHYL-10H-PHENOTHIAZINE, CALCIUM ION, CALMODULIN | 著者 | Vandonselaar, M, Hickie, R.A, Quail, J.W, Delbaere, L.T.J. | 登録日 | 1995-10-11 | 公開日 | 1996-03-08 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Trifluoperazine-induced conformational change in Ca(2+)-calmodulin. Nat.Struct.Biol., 1, 1994
|
|
2KTM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ktm by Molmil](/molmil-images/mine/2ktm) | Solution NMR structure of H2H3 domain of ovine prion protein (residues 167-234) | 分子名称: | Major prion protein | 著者 | Pastore, A, Adrover, M, Pauwels, K, de Chiara, C, Prigent, S, Rezeai, H. | 登録日 | 2010-02-04 | 公開日 | 2010-04-07 | 最終更新日 | 2021-11-10 | 実験手法 | SOLUTION NMR | 主引用文献 | Prion fibrillization is mediated by a native structural element that comprises helices H2 and H3. J.Biol.Chem., 285, 2010
|
|
1GW2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1gw2 by Molmil](/molmil-images/mine/1gw2) | RECOMBINANT HORSERADISH PEROXIDASE C1A THR171SER IN COMPLEX WITH FERULIC ACID | 分子名称: | 3-(4-HYDROXY-3-METHOXYPHENYL)-2-PROPENOIC ACID, CALCIUM ION, PEROXIDASE C1A, ... | 著者 | Henriksen, A, Meno, K, Brissett, N, Gajhede, M. | 登録日 | 2002-03-03 | 公開日 | 2003-03-28 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Hrpc Heme Crevice Architecture To be Published
|
|
6YVA
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6yva by Molmil](/molmil-images/mine/6yva) | PLpro-C111S with mISG15 | 分子名称: | Replicase polyprotein 1a, Ubiquitin-like protein ISG15, ZINC ION | 著者 | Shin, D, Dikic, I. | 登録日 | 2020-04-28 | 公開日 | 2020-05-13 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.18 Å) | 主引用文献 | Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity. Nature, 587, 2020
|
|
1MFQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1mfq by Molmil](/molmil-images/mine/1mfq) | Crystal Structure Analysis of a Ternary S-Domain Complex of Human Signal Recognition Particle | 分子名称: | 7S RNA of human SRP, CHLORIDE ION, MAGNESIUM ION, ... | 著者 | Kuglstatter, A, Oubridge, C, Nagai, K. | 登録日 | 2002-08-13 | 公開日 | 2002-09-20 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Induced structural changes of 7SL RNA during the assembly of human
signal recognition particle Nat.Struct.Biol., 9, 2002
|
|
8BI9
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8bi9 by Molmil](/molmil-images/mine/8bi9) | Structure of a cyclic beta-hairpin peptide derived from neuronal nitric oxide synthase (T112W/T116E variant) | 分子名称: | Nitric oxide synthase, brain, TERTIARY-BUTYL ALCOHOL | 著者 | Balboa, J.R, Ostergaard, S, Stromgaard, K, Knapp, S, Joerger, A.C, Structural Genomics Consortium (SGC) | 登録日 | 2022-11-01 | 公開日 | 2022-12-21 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.44 Å) | 主引用文献 | Development of a Potent Cyclic Peptide Inhibitor of the nNOS/PSD-95 Interaction. J.Med.Chem., 66, 2023
|
|
2ILU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2ilu by Molmil](/molmil-images/mine/2ilu) | |
3EMM
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3emm by Molmil](/molmil-images/mine/3emm) | X-ray structure of protein from Arabidopsis thaliana AT1G79260 with Bound Heme | 分子名称: | 1,2-ETHANEDIOL, PROTOPORPHYRIN IX CONTAINING FE, Uncharacterized protein At1g79260 | 著者 | Bianchetti, C.M, Bingman, C.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | 登録日 | 2008-09-24 | 公開日 | 2008-10-14 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.358 Å) | 主引用文献 | The structure and NO binding properties of the nitrophorin-like heme-binding protein from Arabidopsis thaliana gene locus At1g79260.1. Proteins, 78, 2010
|
|
8P26
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8p26 by Molmil](/molmil-images/mine/8p26) | Crystal structure of Arabidopsis thaliana PAXX | 分子名称: | U2 small nuclear ribonucleoprotein auxiliary factor-like protein | 著者 | Ochi, T. | 登録日 | 2023-05-15 | 公開日 | 2023-06-28 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | 主引用文献 | Plant PAXX has an XLF-like function and stimulates DNA end joining by the Ku-DNA ligase IV/XRCC4 complex. Plant J., 116, 2023
|
|
4XZ2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4xz2 by Molmil](/molmil-images/mine/4xz2) | Human platelet phosphofructokinase in an R-state in complex with ADP and F6P, crystal form I | 分子名称: | 1,6-di-O-phosphono-beta-D-fructofuranose, 6-O-phosphono-beta-D-fructofuranose, ADENOSINE-5'-DIPHOSPHATE, ... | 著者 | Kloos, M, Strater, N. | 登録日 | 2015-02-03 | 公開日 | 2015-06-03 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.67 Å) | 主引用文献 | Crystal structure of human platelet phosphofructokinase-1 locked in an activated conformation. Biochem.J., 469, 2015
|
|