6YVA
PLpro-C111S with mISG15
Summary for 6YVA
Entry DOI | 10.2210/pdb6yva/pdb |
Descriptor | Replicase polyprotein 1a, Ubiquitin-like protein ISG15, ZINC ION, ... (4 entities in total) |
Functional Keywords | deubiquitinase, papain-like-protease, sars-cov-2, isg15, complex, cell invasion |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) More |
Total number of polymer chains | 2 |
Total formula weight | 53640.48 |
Authors | |
Primary citation | Shin, D.,Mukherjee, R.,Grewe, D.,Bojkova, D.,Baek, K.,Bhattacharya, A.,Schulz, L.,Widera, M.,Mehdipour, A.R.,Tascher, G.,Geurink, P.P.,Wilhelm, A.,van der Heden van Noort, G.J.,Ovaa, H.,Muller, S.,Knobeloch, K.P.,Rajalingam, K.,Schulman, B.A.,Cinatl, J.,Hummer, G.,Ciesek, S.,Dikic, I. Papain-like protease regulates SARS-CoV-2 viral spread and innate immunity. Nature, 587:657-662, 2020 Cited by PubMed: 32726803DOI: 10.1038/s41586-020-2601-5 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.18 Å) |
Structure validation
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