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6YVA

PLpro-C111S with mISG15

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Replicase polyprotein 1apolymer31535655.41UniProt (P0DTC1)
Pfam (PF08715)
UniProt (by SIFTS) (P0DTD1)
Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)pp1a,ORF1a polyprotein
2B
(C)
Ubiquitin-like protein ISG15polymer16117919.61UniProt (Q64339)
Pfam (PF00240)
Mus musculus (House mouse)Interferon-induced 15 kDa protein,Interferon-induced 17 kDa protein,IP17,Ubiquitin cross-reactive protein
3C
(C)
ZINC IONnon-polymer65.41Chemie (ZN)
4D, E
(A, C)
waterwater18.023Chemie (HOH)
Sequence modifications
A: 1 - 315 (UniProt: P0DTC1)
PDBExternal DatabaseDetails
Ser 111Cys 1674engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight53575.1
Non-Polymers*Number of molecules1
Total formula weight65.4
All*Total formula weight53640.5
*Water molecules are not included.

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PDB entries from 2025-06-11

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