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1S7S
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BU of 1s7s by Molmil
Crystal structures of the murine class I major histocompatibility complex H-2Kb in complex with LCMV-derived gp33 index peptide and three of its escape variants
分子名称: Beta-2-microglobulin, Glycoprotein 9-residue peptide, H-2 class I histocompatibility antigen, ...
著者Velloso, L.M, Michaelsson, J, Ljunggren, H.G, Schneider, G, Achour, A.
登録日2004-01-30
公開日2004-05-04
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Determination of structural principles underlying three different modes of lymphocytic choriomeningitis virus escape from CTL recognition.
J.Immunol., 172, 2004
1S7Q
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BU of 1s7q by Molmil
Crystal structures of the murine class I major histocompatibility complex H-2Kb in complex with LCMV-derived gp33 index peptide and three of its escape variants
分子名称: Beta-2-microglobulin, Glycoprotein 9-residue peptide, H-2 class I histocompatibility antigen, ...
著者Velloso, L.M, Michaelsson, J, Ljunggren, H.G, Schneider, G, Achour, A.
登録日2004-01-30
公開日2004-05-04
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Determination of structural principles underlying three different modes of lymphocytic choriomeningitis virus escape from CTL recognition.
J.Immunol., 172, 2004
7SU9
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BU of 7su9 by Molmil
KRAS-G12D specific TCR9a in complex with C*05-GADGVGKSL
分子名称: Beta-2-microglobulin, GLYCEROL, KRAS-G12D-9mer with A18L substitution, ...
著者Sim, M.J.W, Sun, P.D.
登録日2021-11-16
公開日2022-06-08
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献T cells discriminate between groups C1 and C2 HLA-C.
Elife, 11, 2022
6C5H
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BU of 6c5h by Molmil
S25-5 Fab in complex with Chlamydiaceae-specific LPS antigen
分子名称: 3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-8)-3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-4)-3-deoxy-alpha-D-manno-oct-2-ulopyranosonic acid-(2-6)-2-amino-2-deoxy-4-O-phosphono-beta-D-glucopyranose-(1-6)-2-amino-2-deoxy-1-O-phosphono-alpha-D-glucopyranose, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Evans, S.V, Haji-Ghassemi, O.
登録日2018-01-16
公開日2019-01-09
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Subtle Changes in the Combining Site of the Chlamydiaceae-Specific mAb S25-23 Increase the Antibody-Carbohydrate Binding Affinity by an Order of Magnitude.
Biochemistry, 58, 2019
5JLZ
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BU of 5jlz by Molmil
Crystal structure of HLA-DRB1*04:01 in complex with modified alpha-enolase peptide 26-40 with citrulline at the position 32
分子名称: Alpha-enolase, HLA class II histocompatibility antigen, DR alpha chain, ...
著者Dubnovitsky, A, Kozhukh, G, Sandalova, T, Achour, A.
登録日2016-04-28
公開日2016-12-07
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Functional and Structural Characterization of a Novel HLA-DRB1*04:01-Restricted alpha-Enolase T Cell Epitope in Rheumatoid Arthritis.
Front Immunol, 7, 2016
2NY1
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BU of 2ny1 by Molmil
HIV-1 gp120 Envelope Glycoprotein (I109C, T257S, S334A, S375W, Q428C) Complexed with CD4 and Antibody 17b
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ANTIBODY 17B, HEAVY CHAIN, ...
著者Zhou, T, Xu, L, Dey, B, Hessell, A.J, Van Ryk, D, Xiang, S.H, Yang, X, Zhang, M.Y, Zwick, M.B, Arthos, J, Burton, D.R, Dimitrov, D.S, Sodroski, J, Wyatt, R, Nabel, G.J, Kwong, P.D.
登録日2006-11-20
公開日2007-02-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Structural definition of a conserved neutralization epitope on HIV-1 gp120.
Nature, 445, 2007
8JQT
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Crystal structure of U03-GPAKGIEYD
分子名称: Beta-2-microglobulin, MHC class I antigen alpha chain, peptide of AIV
著者Tang, Z, Zhang, N.
登録日2023-06-14
公開日2024-06-19
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Structure of duck MHC U03
To Be Published
3ZO0
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BU of 3zo0 by Molmil
Mouse IgG2a in complex with mouse TRIM21 PRYSPRY
分子名称: E3 UBIQUITIN-PROTEIN LIGASE TRIM21, IG GAMMA-2A CHAIN C REGION, A ALLELE, ...
著者James, L.C.
登録日2013-02-19
公開日2013-05-22
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Trim21 is an Igg Receptor that is Structurally, Thermodynamically, and Kinetically Conserved.
Proc.Natl.Acad.Sci.USA, 105, 2008
5GSV
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BU of 5gsv by Molmil
Mouse MHC class I H-2Kd with a MERS-CoV-derived peptide 142-5
分子名称: 10-mer peptide from Spike protein, Beta-2-microglobulin, H-2 class I histocompatibility antigen, ...
著者Liu, K, Chai, Y, Qi, J, Tan, W, Liu, W.J, Gao, G.F.
登録日2016-08-17
公開日2017-04-26
実験手法X-RAY DIFFRACTION (1.996 Å)
主引用文献Protective T Cell Responses Featured by Concordant Recognition of Middle East Respiratory Syndrome Coronavirus-Derived CD8+ T Cell Epitopes and Host MHC.
J. Immunol., 198, 2017
5YMW
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BU of 5ymw by Molmil
Crystal structure of 8-mer peptide from Rous sarcoma virus in complex with BF2*1201
分子名称: Beta-2-microglobulin, Class I histocompatibility antigen, F10 alpha chain, ...
著者Xiao, J, Xiang, W, Qi, J, Chai, Y, Liu, W.J, Gao, G.F.
登録日2017-10-22
公開日2018-10-24
最終更新日2019-07-31
実験手法X-RAY DIFFRACTION (1.997 Å)
主引用文献An Invariant Arginine in Common with MHC Class II Allows Extension at the C-Terminal End of Peptides Bound to Chicken MHC Class I.
J Immunol., 201, 2018
3UPR
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BU of 3upr by Molmil
HLA-B*57:01 complexed to pep-V and Abacavir
分子名称: Beta-2-microglobulin, CHLORIDE ION, HLA class I histocompatibility antigen, ...
著者Pompeu, Y.A, Ostrov, D.A.
登録日2011-11-18
公開日2012-06-13
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.999 Å)
主引用文献Drug hypersensitivity caused by alteration of the MHC-presented self-peptide repertoire.
Proc.Natl.Acad.Sci.USA, 109, 2012
6MSY
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BU of 6msy by Molmil
Anti-HIV-1 Fab Fab 2G12 + Man4 re-refinement
分子名称: ACETATE ION, Fab 2G12, light chain, ...
著者Calarese, D.A, Stanfield, R.L, Wilson, I.A.
登録日2018-10-18
公開日2018-11-21
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.999 Å)
主引用文献Dissection of the carbohydrate specificity of the broadly neutralizing anti-HIV-1 antibody 2G12.
Proc. Natl. Acad. Sci. U.S.A., 102, 2005
5D7I
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BU of 5d7i by Molmil
Structure of human MR1-Ac-6-FP in complex with human MAIT M33.64 TCR
分子名称: Beta-2-microglobulin, GLYCEROL, M33.64 TCR Alpha Chain, ...
著者Keller, A.N, Woolley, R.E, Rossjohn, J.
登録日2015-08-14
公開日2016-01-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Diversity of T Cells Restricted by the MHC Class I-Related Molecule MR1 Facilitates Differential Antigen Recognition.
Immunity, 44, 2016
5KSA
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BU of 5ksa by Molmil
Bel602-DQ8.5-glia-gamma1 complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Bel602 alpha TRAV20*01, Bel602 beta TRBV9*01, ...
著者Petersen, J, Rossjohn, J, Reid, H.H.
登録日2016-07-08
公開日2016-09-21
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Diverse T Cell Receptor Gene Usage in HLA-DQ8-Associated Celiac Disease Converges into a Consensus Binding Solution.
Structure, 24, 2016
6DCW
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BU of 6dcw by Molmil
Crystal structure of human anti-tau antibody CBTAU-27.1 Fab in complex with a human tau peptide
分子名称: Heavy chain of CBTAU27.1 Fab, Light chain of CBTAU27.1 Fab, tau peptide
著者Zhu, X, Zhang, H, Wilson, I.A.
登録日2018-05-08
公開日2018-06-06
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A common antigenic motif recognized by naturally occurring human VH5-51/VL4-1 anti-tau antibodies with distinct functionalities.
Acta Neuropathol Commun, 6, 2018
7P3E
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BU of 7p3e by Molmil
MHC I A02 Allele presenting YLQLRTFLL
分子名称: Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, IODIDE ION, ...
著者Rizkallah, P.J, Sewell, A.K, Wall, A, Fuller, A.
登録日2021-07-07
公開日2021-07-28
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Emergence of immune escape at dominant SARS-CoV-2 killer T cell epitope.
Cell, 185, 2022
8GLF
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BU of 8glf by Molmil
Crystal Structure of Human CD1b in Complex with Sphingomyelin C34:2
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, ...
著者Shahine, A.
登録日2023-03-22
公開日2023-09-20
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献CD1 lipidomes reveal lipid-binding motifs and size-based antigen-display mechanisms.
Cell, 186, 2023
3HPJ
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BU of 3hpj by Molmil
Human Class I MHC HLA-A2 in complex with the WT-1 (126-134) peptide
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Borbulevych, O.Y, Baker, B.M.
登録日2009-06-04
公開日2010-06-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structures of native and affinity-enhanced WT1 epitopes bound to HLA-A*0201: Implications for WT1-based cancer therapeutics.
Mol.Immunol., 47, 2010
3PV7
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BU of 3pv7 by Molmil
Crystal structure of NKp30 ligand B7-H6
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Ig-like domain-containing protein DKFZp686O24166/DKFZp686I21167
著者Li, Y.
登録日2010-12-06
公開日2011-03-16
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of the activating natural killer cell receptor NKp30 bound to its ligand B7-H6 reveals basis for tumor cell recognition in humans
to be published
5VVP
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BU of 5vvp by Molmil
HLA-B*57:03 presenting LSSPVTKSW
分子名称: Beta-2-microglobulin, LEU-SER-SER-PRO-VAL-THR-LYS-SER-TRP, MHC class I antigen
著者Pymm, P, Rossjohn, J, Vivian, J.P.
登録日2017-05-19
公開日2018-10-03
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome.
Nat Commun, 9, 2018
3H9H
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BU of 3h9h by Molmil
Human Class I MHC HLA-A2(A150P) in complex with the Tel1p peptide
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Borbulevych, O.Y, Baker, B.M.
登録日2009-04-30
公開日2010-01-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献T cell receptor cross-reactivity directed by antigen-dependent tuning of peptide-MHC molecular flexibility.
Immunity, 31, 2009
6DIG
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BU of 6dig by Molmil
Crystal structure of DQA1*01:02/DQB1*06:02 in complex with a hypocretin peptide
分子名称: 13-mer peptide: ALA-GLY-ASN-HIS-ALA-ALA-GLY-ILE-LEU-THR-LEU-GLY-LYS, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Birtley, J.R, Stern, L.J, Mellins, E.D, Jiang, W.
登録日2018-05-23
公開日2019-05-08
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献In vivo clonal expansion and phenotypes of hypocretin-specific CD4+T cells in narcolepsy patients and controls.
Nat Commun, 10, 2019
4K7F
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BU of 4k7f by Molmil
Newly identified epitope V60 from HBV core protein complexed with HLA-A*0201
分子名称: Beta-2-microglobulin, Core protein, HLA class I histocompatibility antigen, ...
著者Meng, S.D, Zhang, Y, Wu, Y, Qi, J.X.
登録日2013-04-17
公開日2013-06-05
最終更新日2022-08-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The L60V variation in hepatitis B virus core protein elicits new epitope-specific cytotoxic T lymphocytes and enhances viral replication.
J.Virol., 87, 2013
7RHO
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Human IgG1 Fc fragment, hinge-free, expressed in E. coli
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Fc fragment of human IgG1
著者Gallagher, D.T.
登録日2021-07-18
公開日2022-11-09
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Effects of glycans and hinge on dynamics in the IgG1 Fc.
J.Biomol.Struct.Dyn., 2023
4PGE
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MHC Class I in complex with modified Sendai virus nucleoprotein peptide FAPGNYPAW
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
著者Celie, P, Joosten, R.P, Perrakis, A, Neefjes, J.
登録日2014-05-01
公開日2015-01-07
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The first step of peptide selection in antigen presentation by MHC class I molecules.
Proc.Natl.Acad.Sci.USA, 112, 2015

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