1TW8
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![BU of 1tw8 by Molmil](/molmil-images/mine/1tw8) | HincII bound to Ca2+ and cognate DNA GTCGAC | 分子名称: | 5'-D(*GP*CP*CP*GP*GP*TP*CP*GP*AP*CP*CP*GP*G)-3', CALCIUM ION, Hinc II endonuclease, ... | 著者 | Etzkorn, C, Horton, N.C. | 登録日 | 2004-06-30 | 公開日 | 2004-08-10 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Ca2+ binding in the active site of HincII: implications for the catalytic mechanism Biochemistry, 43, 2004
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1NHJ
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![BU of 1nhj by Molmil](/molmil-images/mine/1nhj) | Crystal structure of N-terminal 40KD MutL/A100P mutant protein complex with ADPnP and one sodium | 分子名称: | DNA mismatch repair protein mutL, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | 著者 | Hu, X, Machius, M, Yang, W. | 登録日 | 2002-12-19 | 公開日 | 2003-06-10 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Monovalent cation dependence and preference of GHKL ATPases and kinases FEBS Lett., 544, 2003
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7VKE
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![BU of 7vke by Molmil](/molmil-images/mine/7vke) | Crystal structure of human CD38 ECD in complex with UniDab(TM) F11A | 分子名称: | 1,2-ETHANEDIOL, ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, CHLORIDE ION, ... | 著者 | Schooten, W.V, Schellenberger, U, Ugamraj, H.S, Manicka, S, Bijpuria, S, Gondu, R.K. | 登録日 | 2021-09-29 | 公開日 | 2022-08-03 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | TNB-738, a biparatopic antibody, boosts intracellular NAD+ by inhibiting CD38 ecto-enzyme activity. Mabs, 14, 2022
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7VXR
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![BU of 7vxr by Molmil](/molmil-images/mine/7vxr) | Crystal structure of BPSL1038 from Burkholderia pseudomallei | 分子名称: | BPSL1038, SODIUM ION | 著者 | Shaibullah, S, Mohd-Sharif, M, Ho, K.L, Firdaus-Raih, M, Nathan, S, Mohamed, R, Teh, A.K, Waterman, J, Ng, C.L. | 登録日 | 2021-11-13 | 公開日 | 2023-08-16 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Structural and functional analyses of Burkholderia pseudomallei BPSL1038 reveal a Cas-2/VapD nuclease sub-family. Commun Biol, 6, 2023
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7VXT
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![BU of 7vxt by Molmil](/molmil-images/mine/7vxt) | Crystal structure of a selenomethionine-labeled BPSL1038 from Burkholderia pseudomallei | 分子名称: | BETA-MERCAPTOETHANOL, BPSL1038, SODIUM ION | 著者 | Shaibullah, S, Mohd-Sharif, M, Ho, K.L, Firdaus-Raih, M, Nathan, S, Mohamed, R, Teh, A.K, Waterman, J, Ng, C.L. | 登録日 | 2021-11-13 | 公開日 | 2023-08-16 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Structural and functional analyses of Burkholderia pseudomallei BPSL1038 reveal a Cas-2/VapD nuclease sub-family. Commun Biol, 6, 2023
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7XMF
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![BU of 7xmf by Molmil](/molmil-images/mine/7xmf) | Cryo-EM structure of human NaV1.7/beta1/beta2-Nav1.7-IN2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 3-[[4-[3-(4-fluoranyl-2-methyl-phenoxy)azetidin-1-yl]pyrimidin-2-yl]amino]-~{N}-methyl-benzamide, ... | 著者 | Zhang, J.T, Jiang, D.H. | 登録日 | 2022-04-25 | 公開日 | 2022-11-30 | 最終更新日 | 2022-12-28 | 実験手法 | ELECTRON MICROSCOPY (3.07 Å) | 主引用文献 | Structural basis for Na V 1.7 inhibition by pore blockers. Nat.Struct.Mol.Biol., 29, 2022
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1GEN
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![BU of 1gen by Molmil](/molmil-images/mine/1gen) | C-TERMINAL DOMAIN OF GELATINASE A | 分子名称: | CALCIUM ION, CHLORIDE ION, GELATINASE A, ... | 著者 | Libson, A.M, Gittis, A.G, Collier, I.E, Marmer, B.L, Goldberg, G.G, Lattman, E.E. | 登録日 | 1995-07-19 | 公開日 | 1996-08-17 | 最終更新日 | 2018-03-21 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Crystal structure of the haemopexin-like C-terminal domain of gelatinase A. Nat.Struct.Biol., 2, 1995
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3F4I
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![BU of 3f4i by Molmil](/molmil-images/mine/3f4i) | Crystal Structure of LeuT bound to L-selenomethionine and sodium | 分子名称: | SELENOMETHIONINE, SODIUM ION, Transporter, ... | 著者 | Singh, S.K, Piscitelli, C.L, Yamashita, A, Gouaux, E. | 登録日 | 2008-10-31 | 公開日 | 2008-12-23 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | A competitive inhibitor traps LeuT in an open-to-out conformation. Science, 322, 2008
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3F4J
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![BU of 3f4j by Molmil](/molmil-images/mine/3f4j) | Crystal structure of LeuT bound to glycine and sodium | 分子名称: | GLYCINE, SODIUM ION, Transporter, ... | 著者 | Singh, S.K, Piscitelli, C.L, Yamashita, A, Gouaux, E. | 登録日 | 2008-10-31 | 公開日 | 2008-12-23 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | A competitive inhibitor traps LeuT in an open-to-out conformation. Science, 322, 2008
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4P5M
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![BU of 4p5m by Molmil](/molmil-images/mine/4p5m) | Structural Basis of Chronic Beryllium Disease: Bridging the Gap Between Allergic Hypersensitivity and Autoimmunity | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)][2-acetamido-2-deoxy-beta-D-glucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Wang, Y, Dai, S, Kappler, J. | 登録日 | 2014-03-18 | 公開日 | 2014-08-27 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural basis of chronic beryllium disease: linking allergic hypersensitivity and autoimmunity. Cell, 158, 2014
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4RKJ
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![BU of 4rkj by Molmil](/molmil-images/mine/4rkj) | Crystal structure of thrombin mutant S195T (free form) | 分子名称: | GLYCEROL, POTASSIUM ION, Thrombin heavy chain, ... | 著者 | Pelc, A.L, Chen, Z, Gohara, D.W, Vogt, A.D, Pozzi, N, Di Cera, E. | 登録日 | 2014-10-13 | 公開日 | 2015-03-11 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Why ser and not thr brokers catalysis in the trypsin fold. Biochemistry, 54, 2015
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2BQ2
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![BU of 2bq2 by Molmil](/molmil-images/mine/2bq2) | Solution Structure of the DNA Duplex ACGCGU-NA with a 2' Amido-Linked Nalidixic Acid Residue at the 3' Terminal Nucleotide | 分子名称: | 5'-D(*AP*CP*GP*CP*GP*2AU)-3', NALIDIXIC ACID | 著者 | Siegmund, K, Maheshwary, S, Narayanan, S, Connors, W, Richert, M. | 登録日 | 2005-04-26 | 公開日 | 2006-08-03 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Molecular details of quinolone-DNA interactions: solution structure of an unusually stable DNA duplex with covalently linked nalidixic acid residues and non-covalent complexes derived from it. Nucleic Acids Res., 33, 2005
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1Y7W
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![BU of 1y7w by Molmil](/molmil-images/mine/1y7w) | Crystal structure of a halotolerant carbonic anhydrase from Dunaliella salina | 分子名称: | ACETIC ACID, Halotolerant alpha-type carbonic anhydrase (dCA II), SODIUM ION, ... | 著者 | Premkumar, L, Greenblatt, H.M, Bageshwar, U.K, Savchenko, T, Gokhman, I, Sussman, J.L, Zamir, A, Israel Structural Proteomics Center (ISPC) | 登録日 | 2004-12-10 | 公開日 | 2005-05-03 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Three-dimensional structure of a halotolerant algal carbonic anhydrase predicts halotolerance of a mammalian homolog. Proc.Natl.Acad.Sci.Usa, 102, 2005
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4NTY
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![BU of 4nty by Molmil](/molmil-images/mine/4nty) | Cesium sites in the crystal structure of acid-sensing ion channel in complex with snake toxin | 分子名称: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, Acid-sensing ion channel 1, Basic phospholipase A2 homolog Tx-beta, ... | 著者 | Baconguis, I, Bohlen, C.J, Goehring, A, Julius, D, Gouaux, E. | 登録日 | 2013-12-02 | 公開日 | 2014-02-19 | 最終更新日 | 2019-12-25 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | X-ray structure of Acid-sensing ion channel 1-snake toxin complex reveals open state of a na(+)-selective channel. Cell(Cambridge,Mass.), 156, 2014
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1GVD
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![BU of 1gvd by Molmil](/molmil-images/mine/1gvd) | CRYSTAL STRUCTURE OF C-MYB R2 V103L MUTANT | 分子名称: | AMMONIUM ION, MYB PROTO-ONCOGENE PROTEIN, SULFATE ION | 著者 | Tahirov, T.H, Ogata, K. | 登録日 | 2002-02-08 | 公開日 | 2003-07-03 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Crystal Structure of C-Myb DNA-Binding Domain: Specific Na+ Binding and Correlation with NMR Structure To be Published
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2HWL
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![BU of 2hwl by Molmil](/molmil-images/mine/2hwl) | Crystal structure of thrombin in complex with fibrinogen gamma' peptide | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Fibrinogen gamma' peptide, Prothrombin, ... | 著者 | Pineda, A.O, Chen, Z.W, Marino, F, Mathews, F.S, Mosesson, M.W, Di Cera, E. | 登録日 | 2006-08-01 | 公開日 | 2006-09-19 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structure of thrombin in complex with fibrinogen gamma' peptide. Biophys.Chem., 125, 2007
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3WUV
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![BU of 3wuv by Molmil](/molmil-images/mine/3wuv) | |
3W8L
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![BU of 3w8l by Molmil](/molmil-images/mine/3w8l) | Crystal structure of human CK2 in complex with inositol hexakisphosphate | 分子名称: | Casein kinase II subunit alpha, INOSITOL HEXAKISPHOSPHATE | 著者 | Son, S.H, Lee, W.-K, Yu, Y.G, Lee, H.H. | 登録日 | 2013-03-15 | 公開日 | 2013-11-13 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural and functional insights into the regulation mechanism of CK2 by IP6 and the intrinsically disordered protein Nopp140 Proc.Natl.Acad.Sci.USA, 110, 2013
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3WUU
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3B28
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![BU of 3b28 by Molmil](/molmil-images/mine/3b28) | Hsp90 alpha N-terminal domain in complex with an inhibitor CH5015765 | 分子名称: | 4-(5-chloro-1H,3H-benzo[de]isochromen-6-yl)-6-(methylsulfanyl)-1,3,5-triazin-2-amine, GLYCEROL, Heat shock protein HSP 90-alpha, ... | 著者 | Fukami, T.A, Ono, N. | 登録日 | 2011-07-21 | 公開日 | 2011-09-14 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Lead generation of heat shock protein 90 inhibitors by a combination of fragment-based approach, virtual screening, and structure-based drug design Bioorg.Med.Chem.Lett., 21, 2011
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3WUT
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![BU of 3wut by Molmil](/molmil-images/mine/3wut) | Structure basis of inactivating cell abscission | 分子名称: | Centrosomal protein of 55 kDa, GLYCEROL, Inactive serine/threonine-protein kinase TEX14 | 著者 | Kim, H.J, Matsuura, A, Lee, H.H. | 登録日 | 2014-05-05 | 公開日 | 2015-07-15 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.301 Å) | 主引用文献 | Structural and biochemical insights into the role of testis-expressed gene 14 (TEX14) in forming the stable intercellular bridges of germ cells. Proc.Natl.Acad.Sci.USA, 112, 2015
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1QJ3
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![BU of 1qj3 by Molmil](/molmil-images/mine/1qj3) | Crystal structure of 7,8-diaminopelargonic acid synthase in complex with 7-keto-8-aminopelargonic acid | 分子名称: | 7,8-DIAMINOPELARGONIC ACID SYNTHASE, 7-KETO-8-AMINOPELARGONIC ACID, PYRIDOXAL-5'-PHOSPHATE, ... | 著者 | Kaeck, H, Sandmark, J, Gibson, K.J, Lindqvist, Y, Schneider, G. | 登録日 | 1999-06-21 | 公開日 | 2000-06-22 | 最終更新日 | 2019-05-08 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal Structure of Diaminopelargonic Acid Synthase; Evolutionary Relationships between Pyridoxal-5'-Phosphate Dependent Enzymes J.Mol.Biol., 291, 1999
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1GWD
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![BU of 1gwd by Molmil](/molmil-images/mine/1gwd) | Tri-iodide derivative of hen egg-white lysozyme | 分子名称: | 1,2-ETHANEDIOL, CARBON MONOXIDE, CHLORIDE ION, ... | 著者 | Evans, G, Bricogne, G. | 登録日 | 2002-03-14 | 公開日 | 2002-06-06 | 最終更新日 | 2017-06-28 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Triiodide Derivatization and Combinatorial Counter-Ion Replacement: Two Methods for Enhancing Phasing Signal Using Laboratory Cu Kalpha X-Ray Equipment Acta Crystallogr.,Sect.D, 58, 2002
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2BEC
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![BU of 2bec by Molmil](/molmil-images/mine/2bec) | Crystal structure of CHP2 in complex with its binding region in NHE1 and insights into the mechanism of pH regulation | 分子名称: | Calcineurin B homologous protein 2, Sodium/hydrogen exchanger 1, YTTRIUM (III) ION | 著者 | Ben Ammar, Y, Takeda, S, Hisamitsu, T, Mori, H, Wakabayashi, S. | 登録日 | 2005-10-24 | 公開日 | 2006-06-27 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structure of CHP2 complexed with NHE1-cytosolic region and an implication for pH regulation Embo J., 25, 2006
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2D10
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![BU of 2d10 by Molmil](/molmil-images/mine/2d10) | |