3W8L

Crystal structure of human CK2 in complex with inositol hexakisphosphate

Summary for 3W8L

Entry DOI	10.2210/pdb3w8l/pdb
Descriptor	Casein kinase II subunit alpha, INOSITOL HEXAKISPHOSPHATE (3 entities in total)
Functional Keywords	protein kinase ck2, apoptosis
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	81425.50
Authors	Son, S.H.,Lee, W.-K.,Yu, Y.G.,Lee, H.H. (deposition date: 2013-03-15, release date: 2013-11-13, Last modification date: 2023-11-08)
Primary citation	Lee, W.-K.,Son, S.H.,Jin, B.-S.,Na, J.-H.,Kim, S.-Y.,Kim, K.H.,Kim, E.E.,Yu, Y.G.,Lee, H.H. Structural and functional insights into the regulation mechanism of CK2 by IP6 and the intrinsically disordered protein Nopp140 Proc.Natl.Acad.Sci.USA, 110:19360-19365, 2013 Cited by PubMed: 24218616 DOI: 10.1073/pnas.1304670110 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation