4KXU
 
 | | Human transketolase in covalent complex with donor ketose D-fructose-6-phosphate | | 分子名称: | 1,2-ETHANEDIOL, D-SORBITOL-6-PHOSPHATE, MAGNESIUM ION, ... | | 著者 | Neumann, P, Luedtke, S, Ficner, R, Tittmann, K. | | 登録日 | 2013-05-28 | | 公開日 | 2013-08-21 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (0.98 Å) | | 主引用文献 | Sub-angstrom-resolution crystallography reveals physical distortions that enhance reactivity of a covalent enzymatic intermediate.
Nat Chem, 5, 2013
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4MAT
 | | E.COLI METHIONINE AMINOPEPTIDASE HIS79ALA MUTANT | | 分子名称: | PROTEIN (METHIONINE AMINOPEPTIDASE), SODIUM ION | | 著者 | Lowther, W.T, Orville, A.M, Madden, D.T, Lim, S, Rich, D.H, Matthews, B.W. | | 登録日 | 1999-03-29 | | 公開日 | 1999-06-18 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Escherichia coli methionine aminopeptidase: implications of crystallographic analyses of the native, mutant, and inhibited enzymes for the mechanism of catalysis.
Biochemistry, 38, 1999
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2DDB
 | | Crystal structure of pseudecin from Pseudechis porphyriacus | | 分子名称: | FORMIC ACID, GLYCEROL, Pseudecin, ... | | 著者 | Suzuki, N, Yamazaki, Y, Fujimoto, Z, Morita, T, Mizuno, H. | | 登録日 | 2006-01-25 | | 公開日 | 2007-01-30 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structures of pseudechetoxin and pseudecin, two snake-venom cysteine-rich secretory proteins that target cyclic nucleotide-gated ion channels: implications for movement of the C-terminal cysteine-rich domain
Acta Crystallogr.,Sect.D, 64, 2008
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4M1N
 | | Crystal structure of Plasmodium falciparum ubiquitin conjugating enzyme UBC9 | | 分子名称: | SODIUM ION, Ubiquitin conjugating enzyme UBC9 | | 著者 | Boucher, L.E, Reiter, K.H, Bosch, J, Matunis, J.M. | | 登録日 | 2013-08-03 | | 公開日 | 2013-08-21 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Identification of Biochemically Distinct Properties of the Small Ubiquitin-related Modifier (SUMO) Conjugation Pathway in Plasmodium falciparum.
J.Biol.Chem., 288, 2013
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4M7P
 | | Ensemble refinement of protein crystal structure of macrolide glycosyltransferases OleD | | 分子名称: | Oleandomycin glycosyltransferase, SODIUM ION | | 著者 | Wang, F, Helmich, K.E, Xu, W, Singh, S, Olmos Jr, J.L, Martinez iii, E, Bingman, C.A, Thorson, J.S, Phillips Jr, G.N, Enzyme Discovery for Natural Product Biosynthesis (NatPro) | | 登録日 | 2013-08-12 | | 公開日 | 2013-09-11 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | Crystal structure of macrolide glycosyltransferases OleD
To be Published
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1JAX
 | | Structure of Coenzyme F420H2:NADP+ Oxidoreductase (FNO) | | 分子名称: | MAGNESIUM ION, SODIUM ION, conserved hypothetical protein | | 著者 | Warkentin, E, Mamat, B, Thauer, R, Ermler, U, Shima, S. | | 登録日 | 2001-06-01 | | 公開日 | 2001-12-21 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structures of F420H2:NADP+ oxidoreductase with and without its substrates bound.
EMBO J., 20, 2001
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4L8G
 | | Crystal Structure of K-Ras G12C, GDP-bound | | 分子名称: | GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | | 著者 | Ostrem, J.M, Peters, U, Sos, M.L, Wells, J.A, Shokat, K.M. | | 登録日 | 2013-06-17 | | 公開日 | 2013-11-27 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.521 Å) | | 主引用文献 | K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions.
Nature, 503, 2013
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4LCI
 | | Anti canine CD28 antibody, 1C6 | | 分子名称: | FORMIC ACID, GLYCEROL, SODIUM ION, ... | | 著者 | Gewe, M.M, Rupert, P.B, Strong, R.K. | | 登録日 | 2013-06-21 | | 公開日 | 2014-06-25 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Anti canine CD28 antibody, 1C6
To be Published
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1WBQ
 | | ZnMg substituted aminopeptidase P from E. coli | | 分子名称: | CHLORIDE ION, MAGNESIUM ION, XAA-PRO AMINOPEPTIDASE, ... | | 著者 | Graham, S.C, Bond, C.S, Freeman, H.C, Guss, J.M. | | 登録日 | 2004-11-05 | | 公開日 | 2005-09-29 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural and Functional Implications of Metal Ion Selection in Aminopeptidase P, a Metalloprotease with a Dinuclear Metal Center.
Biochemistry, 44, 2005
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4M0W
 | | Crystal Structure of SARS-CoV papain-like protease C112S mutant in complex with ubiquitin | | 分子名称: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, GLYCEROL, Replicase polyprotein 1a, ... | | 著者 | Chou, C.-Y, Chen, H.-Y, Lai, H.-Y, Cheng, S.-C, Chou, Y.-W. | | 登録日 | 2013-08-02 | | 公開日 | 2014-02-12 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Structural basis for catalysis and ubiquitin recognition by the severe acute respiratory syndrome coronavirus papain-like protease
Acta Crystallogr.,Sect.D, 70, 2014
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4M4O
 | | Crystal structure of the aptamer minE-lysozyme complex | | 分子名称: | Lysozyme C, MAGNESIUM ION, RNA (59-MER), ... | | 著者 | Malashkevich, V.N, Padlan, F.C, Toro, R, Girvin, M, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | | 登録日 | 2013-08-07 | | 公開日 | 2013-12-18 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal structure of the aptamer minE-lysozyme complex
to be published
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4M8T
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2DDA
 | | Crystal structure of pseudechetoxin from Pseudechis australis | | 分子名称: | FORMIC ACID, GLYCEROL, Pseudechetoxin, ... | | 著者 | Suzuki, N, Yamazaki, Y, Fujimoto, Z, Morita, T, Mizuno, H. | | 登録日 | 2006-01-25 | | 公開日 | 2007-01-30 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | Structures of pseudechetoxin and pseudecin, two snake-venom cysteine-rich secretory proteins that target cyclic nucleotide-gated ion channels: implications for movement of the C-terminal cysteine-rich domain
Acta Crystallogr.,Sect.D, 64, 2008
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4LXI
 | | Crystal Structure of the S105A mutant of a carbon-carbon bond hydrolase, DxnB2 from Sphingomonas wittichii RW1, in complex with 5,8-diF HOPDA | | 分子名称: | (3E,5R)-5-fluoro-6-(2-fluorophenyl)-2,6-dioxohex-3-enoic acid, MCP Hydrolase, SODIUM ION | | 著者 | Bhowmik, S, Bolin, J.T. | | 登録日 | 2013-07-29 | | 公開日 | 2013-10-09 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | | 主引用文献 | A substrate-assisted mechanism of nucleophile activation in a ser-his-asp containing C-C bond hydrolase.
Biochemistry, 52, 2013
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4LYI
 | | Crystal Structure of apo-BRD4(1) | | 分子名称: | 1,2-ETHANEDIOL, Bromodomain-containing protein 4, IODIDE ION, ... | | 著者 | Wohlwend, D. | | 登録日 | 2013-07-31 | | 公開日 | 2014-01-15 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | 4-Acyl pyrroles: mimicking acetylated lysines in histone code reading.
Angew.Chem.Int.Ed.Engl., 52, 2013
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1S6P
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4LDK
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4L8P
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4L5R
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1S9G
 | | CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) IN COMPLEX WITH JANSSEN-R120394. | | 分子名称: | 4-[4-AMINO-6-(5-CHLORO-1H-INDOL-4-YLMETHYL)-[1,3,5]TRIAZIN-2-YLAMINO]-BENZONITRILE, POL polyprotein [Contains: Reverse transcriptase] | | 著者 | Das, K, Clark Jr, A.D, Ludovici, D.W, Kukla, M.J, Decorte, B, Lewi, P.J, Hughes, S.H, Janssen, P.A, Arnold, E. | | 登録日 | 2004-02-04 | | 公開日 | 2004-05-11 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Roles of Conformational and Positional Adaptability in Structure-Based Design of TMC125-R165335 (Etravirine) and Related Non-nucleoside Reverse Transcriptase Inhibitors That Are Highly Potent and Effective against Wild-Type and Drug-Resistant HIV-1 Variants.
J.Med.Chem., 47, 2004
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1SUQ
 | | CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE (RT) IN COMPLEX WITH JANSSEN-R185545 | | 分子名称: | (6-[4-(AMINOMETHYL)-2,6-DIMETHYLPHENOXY]-2-{[4-(AMINOMETHYL)PHENYL]AMINO}-5-BROMOPYRIMIDIN-4-YL)METHANOL, MAGNESIUM ION, REVERSE TRANSCRIPTASE | | 著者 | Das, K, Arnold, E. | | 登録日 | 2004-03-26 | | 公開日 | 2004-05-11 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Roles of Conformational and Positional Adaptability in Structure-Based Design of TMC125-R165335 (Etravirine) and Related Non-nucleoside Reverse Transcriptase Inhibitors That Are Highly Potent and Effective against Wild-Type and Drug-Resistant HIV-1 Variants
J.Med.Chem., 47, 2004
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4LHL
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2BHD
 | | Mg substituted E. coli Aminopeptidase P in complex with product | | 分子名称: | CITRATE ANION, MAGNESIUM ION, VALINE-PROLINE-LEUCINE TRIPEPTIDE, ... | | 著者 | Graham, S.C, Bond, C.S, Freeman, H.C, Guss, J.M. | | 登録日 | 2005-01-10 | | 公開日 | 2005-09-29 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural and Functional Implications of Metal Ion Selection in Aminopeptidase P, a Metalloprotease with a Dinuclear Metal Center.
Biochemistry, 44, 2005
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2BHA
 | | E. coli Aminopeptidase P in complex with substrate | | 分子名称: | CITRATE ANION, MAGNESIUM ION, VALINE-PROLINE-LEUCINE, ... | | 著者 | Graham, S.C, Bond, C.S, Freeman, H.C, Guss, J.M. | | 登録日 | 2005-01-08 | | 公開日 | 2005-09-29 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural and Functional Implications of Metal Ion Selection in Aminopeptidase P, a Metalloprotease with a Dinuclear Metal Center.
Biochemistry, 44, 2005
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1EAU
 | | NONPEPTIDIC INHIBITORS OF HUMAN LEUKOCYTE ELASTASE. 6. DESIGN OF A POTENT, INTRATRACHEALLY ACTIVE, PYRIDONE-BASED TRIFLUOROMETHYL KETONE | | 分子名称: | 2-[5-AMINO-6-OXO-2-(2-THIENYL)-1,6-DIHYDROPYRIMIDIN-1-YL)-N-[3,3-DIFLUORO -1-ISOPROPYL-2-OXO-3-(N-(2-MORPHOLINO ETHYL)CARBAMOYL]PROPYL]ACETAMIDE, PORCINE PANCREATIC ELASTASE, SODIUM ION, ... | | 著者 | Ceccarelli, C. | | 登録日 | 1994-11-22 | | 公開日 | 1995-02-07 | | 最終更新日 | 2024-06-05 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Nonpeptidic inhibitors of human leukocyte elastase. 6. Design of a potent, intratracheally active, pyridone-based trifluoromethyl ketone.
J.Med.Chem., 38, 1995
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