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3WYQ
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Crystal structure of the low-immunogenic core streptavidin mutant LISA-314 (Y22S/Y83S/R84K/E101D/R103K/E116N) at 1.0 A resolution
分子名称: BIOTIN, GLYCEROL, SULFATE ION, ...
著者Kawato, T, Mizohata, E, Meshizuka, T, Doi, H, Kawamura, T, Matsumura, H, Yumura, K, Tsumoto, K, Kodama, T, Inoue, T, Sugiyama, A.
登録日2014-09-05
公開日2014-12-24
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献Crystal structure of streptavidin mutant with low immunogenicity.
J.Biosci.Bioeng., 119, 2015
4DKF
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BU of 4dkf by Molmil
Crystal Structure of Human Interleukin-34 Bound to FAb2
分子名称: FAb2 Heavy Chain, FAb2 Light Chain, Interleukin-34, ...
著者Ma, X, Chen, Y, Stawicki, S, Wu, Y, Bazan, J.F, Starovasnik, M.A.
登録日2012-02-03
公開日2012-04-11
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.61 Å)
主引用文献Structural Basis for the Dual Recognition of Helical Cytokines IL-34 and CSF-1 by CSF-1R.
Structure, 20, 2012
3WYP
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BU of 3wyp by Molmil
Crystal structure of wild-type core streptavidin in complex with D-biotin/biotin-D-sulfoxide at 1.3 A resolution
分子名称: BIOTIN, BIOTIN-D-SULFOXIDE, GLYCEROL, ...
著者Kawato, T, Mizohata, E, Meshizuka, T, Doi, H, Kawamura, T, Matsumura, H, Yumura, K, Tsumoto, K, Kodama, T, Inoue, T, Sugiyama, A.
登録日2014-09-05
公開日2014-12-24
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Crystal structure of streptavidin mutant with low immunogenicity.
J.Biosci.Bioeng., 119, 2015
4ARN
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BU of 4arn by Molmil
Crystal structure of the N-terminal domain of Drosophila Toll receptor
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, MALONATE ION, ...
著者Gangloff, M, Gay, N.J.
登録日2012-04-25
公開日2013-01-23
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Functional Insights from the Crystal Structure of the N-Terminal Domain of the Prototypical Toll Receptor.
Structure, 21, 2013
2CDE
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BU of 2cde by Molmil
Structure and binding kinetics of three different human CD1d-alpha- Galactosylceramide specific T cell receptors - iNKT-TCR
分子名称: INKT-TCR
著者Gadola, S.D, Koch, M, Marles-Wright, J, Lissin, N.M, Sheperd, D, Matulis, G, Harlos, K, Villiger, P.M, Stuart, D.I, Jakobsen, B.K, Cerundolo, V, Jones, E.Y.
登録日2006-01-23
公開日2006-03-07
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structrue and Binding Kinetics of Three Different Human Cd1D-Alpha-Galactosylceramide-Specific T Cell Receptors
J.Exp.Med., 203, 2006
2CDG
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BU of 2cdg by Molmil
Structure and binding kinetics of three different human CD1d-alpha- Galactosylceramide-specific T cell receptors (TCR 5B)
分子名称: TCR 5E
著者Gadola, S.D, Koch, M, Marles-Wright, J, Lissin, N.M, Sheperd, D, Matulis, G, Harlos, K, Villiger, P.M, Stuart, D.I, Jakobsen, B.K, Cerundolo, V, Jones, E.Y.
登録日2006-01-23
公開日2006-03-07
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structrue and Binding Kinetics of Three Different Human Cd1D-Alpha-Galactosylceramide-Specific T Cell Receptors
J.Exp.Med., 203, 2006
4A86
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BU of 4a86 by Molmil
Crystal Structure of Major Birch Pollen Allergen Bet v 1 a in ternary complex with kinetin and 8-Anilinonaphthalene-1-sulfonate (ANS)
分子名称: 8-ANILINO-1-NAPHTHALENE SULFONATE, MAJOR POLLEN ALLERGEN BET V 1-A, N-(FURAN-2-YLMETHYL)-7H-PURIN-6-AMINE, ...
著者Kofler, S, Brandstetter, H.
登録日2011-11-18
公開日2012-05-30
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Crystallographically Mapped Ligand Binding Differs in High and Low Ige Binding Isoforms of Birch Pollen Allergen Bet V 1.
J.Mol.Biol., 422, 2012
7CBC
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BU of 7cbc by Molmil
Crystal structure of a de novo designed switch protein caging a hemagglutinin binder
分子名称: De novo designed switch protein caging a hemagglutinin binder (sCageHA267_1S), ETHANOL
著者Lee, H, Oh, B.-H, Baker, D.
登録日2020-06-11
公開日2020-12-23
最終更新日2021-03-31
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献De novo design of modular and tunable protein biosensors.
Nature, 591, 2021
6GCU
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BU of 6gcu by Molmil
MET receptor in complex with InlB internalin domain and DARPin A3A
分子名称: DARPin A3A, Hepatocyte growth factor receptor, Internalin B
著者Meyer, T, Andres, F, Iamele, L, Gherardi, E, Pluckthun, A, Niemann, H.H.
登録日2018-04-19
公開日2019-05-15
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (6.001 Å)
主引用文献Inhibition of the MET Kinase Activity and Cell Growth in MET-Addicted Cancer Cells by Bi-Paratopic Linking.
J.Mol.Biol., 431, 2019
4DKE
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BU of 4dke by Molmil
Crystal Structure of Human Interleukin-34 Bound to FAb1.1
分子名称: FAb1.1 Heavy Chain, FAb1.1 Light Chain, Interleukin-34, ...
著者Ma, X, Chen, Y, Stawicki, S, Wu, Y, Bazan, J.F, Starovasnik, M.A.
登録日2012-02-03
公開日2012-04-11
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural Basis for the Dual Recognition of Helical Cytokines IL-34 and CSF-1 by CSF-1R.
Structure, 20, 2012
2CDF
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BU of 2cdf by Molmil
Structure and binding kinetics of three different human CD1d-alpha- Galactosylceramide-specific T cell receptors (TCR 5E)
分子名称: TCR 5E
著者Gadola, S.D, Koch, M, Marles-Wright, J, Lissin, N.M, Sheperd, D, Matulis, G, Harlos, K, Villiger, P.M, Stuart, D.I, Jakobsen, B.K, Cerundolo, V, Jones, E.Y.
登録日2006-01-23
公開日2006-03-07
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structrue and Binding Kinetics of Three Different Human Cd1D-Alpha-Galactosylceramide-Specific T Cell Receptors
J.Exp.Med., 203, 2006
3X0F
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BU of 3x0f by Molmil
Crystal structure of the ectodomain of mouse CD81 large extracellular loop (mCD81-LEL)
分子名称: CD81 antigen, ISOPROPYL ALCOHOL
著者Zhang, M, Cui, S.
登録日2014-10-14
公開日2015-07-01
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.471 Å)
主引用文献An intramolecular bond at cluster of differentiation 81 ectodomain is important for hepatitis C virus entry.
Faseb J., 29, 2015
3X0E
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BU of 3x0e by Molmil
Crystal structure of the ectodomain of human CD81 large extracellular loop (hCD81-LEL)
分子名称: CD81 antigen, MAGNESIUM ION
著者Zhang, M, Cui, S.
登録日2014-10-14
公開日2015-07-01
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.844 Å)
主引用文献An intramolecular bond at cluster of differentiation 81 ectodomain is important for hepatitis C virus entry.
Faseb J., 29, 2015
6H15
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BU of 6h15 by Molmil
Structure of LRP6 P3E3P4E4 in complex with VHH L-P2-B10
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
著者Gros, P, van Scherpenzeel, R.C.
登録日2018-07-11
公開日2019-01-30
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Anti-LRP5/6 VHHs promote differentiation of Wnt-hypersensitive intestinal stem cells.
Nat Commun, 10, 2019
4BUH
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BU of 4buh by Molmil
Human IgE against the major allergen Bet v 1 - Crystal structure of clone M0418 scFv
分子名称: 1,2-ETHANEDIOL, CLONE M0418 SCFV, DI(HYDROXYETHYL)ETHER
著者Davies, A.M, Levin, M, Lilljekvist, M, Carlsson, F, Gould, H.J, Sutton, B.J, Ohlin, M.
登録日2013-06-20
公開日2013-11-20
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Human Ige Against the Major Allergen Bet V 1 - Defining an Epitope with Limited Cross-Reactivity between Different Pr-10 Family Proteins
Clin.Exp.Allergy, 44, 2014
4CDH
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BU of 4cdh by Molmil
Crystallographic structure of the Human Igg1 alpha 2-6 sialilated Fc-Fragment
分子名称: IG GAMMA-1 CHAIN C REGION, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Silva-Martin, N, Bartual, S.G, Hermoso, J.A.
登録日2013-10-31
公開日2014-11-12
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Basis for Selective Recognition of Endogenous and Microbial Polysaccharides by Macrophage Receptor Sign-R1
Structure, 22, 2014
4BSS
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BU of 4bss by Molmil
Structure of the ectodomain of LGR5 in complex with R-spondin-1 (Fu1Fu2) in P21 crystal form
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5, ...
著者Peng, W.C, de Lau, W, Forneris, F, Granneman, J.C.M, Huch, M, Clevers, H, Gros, P.
登録日2013-06-11
公開日2013-06-19
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure of Stem Cell Growth Factor R-Spondin 1 in Complex with the Ectodomain of its Receptor Lgr5.
Cell Rep., 3, 2013
4BSU
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BU of 4bsu by Molmil
Structure of the ectodomain of LGR5 in complex with R-spondin-1 (Fu1Fu2) in C2 crystal form
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5, ...
著者Peng, W.C, de Lau, W, Forneris, F, Granneman, J.C.M, Huch, M, Clevers, H, Gros, P.
登録日2013-06-11
公開日2013-06-26
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure of Stem Cell Growth Factor R-Spondin 1 in Complex with the Ectodomain of its Receptor Lgr5.
Cell Rep., 3, 2013
4DKD
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BU of 4dkd by Molmil
Crystal Structure of Human Interleukin-34 Bound to Human CSF-1R
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-34, ...
著者Ma, X, Bazan, J.F, Starovasnik, M.A.
登録日2012-02-03
公開日2012-04-11
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural Basis for the Dual Recognition of Helical Cytokines IL-34 and CSF-1 by CSF-1R.
Structure, 20, 2012
3ZLQ
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BU of 3zlq by Molmil
BACE2 XAPERONE COMPLEX
分子名称: 5-Ethoxy-pyridine-2-carboxylic acid [3-((R)-2-amino-5,5-difluoro-4-methyl-5,6-dihydro-4H-[1,3]oxazin-4-yl)-4-fluoro-phenyl]-amide, BETA-SECRETASE 2, XA4813
著者Kuglstatter, A, Stihle, M.
登録日2013-02-04
公開日2013-05-01
最終更新日2013-06-05
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Beta-Secretase (Bace1) Inhibitors with High in Vivo Efficacy Suitable for Clinical Evaluation in Alzheimer'S Disease.
J.Med.Chem., 56, 2013
3ZHG
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BU of 3zhg by Molmil
Crystallographic structure of the native mouse SIGN-R1 CRD domain
分子名称: CALCIUM ION, CD209 ANTIGEN-LIKE PROTEIN B, SULFATE ION
著者Silva-Martin, N, Bartual, S.G, Hermoso, J.A.
登録日2012-12-21
公開日2014-01-15
最終更新日2020-03-11
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Structural Basis for Selective Recognition of Endogenous and Microbial Polysaccharides by Macrophage Receptor Sign-R1.
Structure, 22, 2014
4DKC
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BU of 4dkc by Molmil
Crystal Structure of Human Interleukin-34
分子名称: Interleukin-34, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Ma, X, Bazan, J.F, Starovasnik, M.A.
登録日2012-02-03
公開日2012-04-11
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural Basis for the Dual Recognition of Helical Cytokines IL-34 and CSF-1 by CSF-1R.
Structure, 20, 2012
3ZQK
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BU of 3zqk by Molmil
Von Willebrand Factor A2 domain with calcium
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, GLYCEROL, ...
著者Jakobi, A.J, Huizinga, E.G.
登録日2011-06-09
公開日2011-07-27
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Calcium Modulates Force Sensing by the Von Willebrand Factor A2 Domain.
Nat.Commun., 2, 2011
4BSP
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BU of 4bsp by Molmil
Crystal structure of R-spondin 1 (Fu1Fu2) - Holmium soak
分子名称: HOLMIUM ATOM, R-SPONDIN-1, SULFATE ION
著者Peng, W.C, de Lau, W, Forneris, F, Granneman, J.C.M, Huch, M, Clevers, H, Gros, P.
登録日2013-06-11
公開日2013-06-19
最終更新日2013-07-24
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of Stem Cell Growth Factor R-Spondin 1 in Complex with the Ectodomain of its Receptor Lgr5.
Cell Rep., 3, 2013
4BSR
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BU of 4bsr by Molmil
Structure of the ectodomain of LGR5 in complex with R-spondin-1 (Fu1Fu2) in P22121 crystal form
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, LEUCINE-RICH REPEAT-CONTAINING G-PROTEIN COUPLED RECEPTOR 5, ...
著者Peng, W.C, de Lau, W, Forneris, F, Granneman, J.C.M, Huch, M, Clevers, H, Gros, P.
登録日2013-06-11
公開日2013-06-19
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structure of Stem Cell Growth Factor R-Spondin 1 in Complex with the Ectodomain of its Receptor Lgr5.
Cell Rep., 3, 2013

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