6GCU
MET receptor in complex with InlB internalin domain and DARPin A3A
Summary for 6GCU
Entry DOI | 10.2210/pdb6gcu/pdb |
Descriptor | Hepatocyte growth factor receptor, Internalin B, DARPin A3A (3 entities in total) |
Functional Keywords | receptor tyrosine kinase, bacterial invasion protein, artificial binding protein, signaling protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 265413.05 |
Authors | Meyer, T.,Andres, F.,Iamele, L.,Gherardi, E.,Pluckthun, A.,Niemann, H.H. (deposition date: 2018-04-19, release date: 2019-05-15, Last modification date: 2024-01-17) |
Primary citation | Andres, F.,Iamele, L.,Meyer, T.,Stuber, J.C.,Kast, F.,Gherardi, E.,Niemann, H.H.,Pluckthun, A. Inhibition of the MET Kinase Activity and Cell Growth in MET-Addicted Cancer Cells by Bi-Paratopic Linking. J.Mol.Biol., 431:2020-2039, 2019 Cited by PubMed: 30930049DOI: 10.1016/j.jmb.2019.03.024 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (6.001 Å) |
Structure validation
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