6GCU

MET receptor in complex with InlB internalin domain and DARPin A3A

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D (A, D)	Hepatocyte growth factor receptor	polymer	727	81949.0	2	UniProt (P08581) Pfam (PF01403) Pfam (PF01437) Pfam (PF01833)	Homo sapiens (Human)	HGF receptor,HGF/SF receptor,Proto-oncogene c-Met,Scatter factor receptor,SF receptor,Tyrosine-protein kinase Met
2	B, E (B, E)	Internalin B	polymer	289	32243.8	2	UniProt (P25147) UniProt (by SIFTS) (P0DQD3)	Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)
3	C, F (C, F)	DARPin A3A	polymer	173	18513.7	2		synthetic construct

Sequence modifications

A, D: 25 - 741 (UniProt: P08581)

PDB	External Database	Details
Glu 22	-	expression tag
Thr 23	-	expression tag
Arg 24	-	expression tag
Leu 742	-	expression tag
His 743	-	expression tag
His 744	-	expression tag
His 745	-	expression tag
His 746	-	expression tag
His 747	-	expression tag
His 748	-	expression tag

B, E: 36 - 321 (UniProt: P25147)

PDB	External Database	Details
Gly 33	-	expression tag
Ala 34	-	expression tag
Met 35	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	265413.1
All*	Total formula weight	265413.1

*Water molecules are not included.