PDB: 66311 件ウェブページステータス検索Chemie searchBIRD

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5Z9G	Crystal structure of KAI2 分子名称: Probable esterase KAI2 著者 Kim, K.L, Cha, J.S, Soh, M.S, Cho, H.S. 登録日 2018-02-03 公開日 2018-08-22 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 A missense allele of KARRIKIN-INSENSITIVE2 impairs ligand-binding and downstream signaling in Arabidopsis thaliana. J. Exp. Bot., 69, 2018
2QCC	Crystal structure of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase, apo form 分子名称: GLYCEROL, Orotidine 5'- phosphate decarboxylase (OMPdecase), SULFATE ION 著者 Wittmann, J, Rudolph, M. 登録日 2007-06-19 公開日 2007-11-06 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design. Structure, 16, 2008
2QCL	Crystal structure of the orotidine-5'-monophosphate decarboxylase domain (Asp312Asn mutant) of human UMP synthase bound to OMP 分子名称: GLYCEROL, OROTIDINE-5'-MONOPHOSPHATE, Uridine 5'-monophosphate synthase (UMP synthase) 著者 Wittmann, J, Rudolph, M. 登録日 2007-06-19 公開日 2007-11-06 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design. Structure, 16, 2008
2QCM	Crystal structure of the orotidine-5'-monophosphate decarboxylase domain (Asp312Asn mutant) of human UMP synthase bound to 6-hydroxymethyl-UMP 分子名称: 6-(HYDROXYMETHYL)URIDINE 5'-(DIHYDROGEN PHOSPHATE), Uridine 5'-monophosphate synthase (UMP synthase) 著者 Wittmann, J, Rudolph, M. 登録日 2007-06-19 公開日 2007-11-06 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design. Structure, 16, 2008
2QCH	Crystal structure of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase bound to 5-iodo-UMP 分子名称: 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 5-IODO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, IODIDE ION, ... 著者 Wittmann, J, Rudolph, M. 登録日 2007-06-19 公開日 2007-11-06 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design. Structure, 16, 2008
2QCN	Covalent complex of the orotidine-5'-monophosphate decarboxylase domain of human UMP synthase with 6-iodo-UMP 分子名称: GLYCEROL, SULFATE ION, URIDINE-5'-MONOPHOSPHATE, ... 著者 Wittmann, J, Rudolph, M. 登録日 2007-06-19 公開日 2007-11-13 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Structures of the human orotidine-5'-monophosphate decarboxylase support a covalent mechanism and provide a framework for drug design. Structure, 16, 2008
7Z4S	Crystal structure of SARS-CoV-2 Mpro in complex with cyclic peptide GM4 including unnatural amino acids. 分子名称: 1,2-ETHANEDIOL, 3C-like proteinase nsp5, DI(HYDROXYETHYL)ETHER, ... 著者 Owen, C.D, Miura, T, Malla, T, Lukacik, L, Strain-Damerell, C.M, Tumber, A, Brewitz, L, McDonough, M.A, Salah, E, Terasaka, N, Katoh, T, Kawamura, A, Schofield, C.J, Suga, H, Walsh, M.A. 登録日 2022-03-04 公開日 2023-03-22 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 In vitro selection of macrocyclic peptide inhibitors containing cyclic gamma 2,4 -amino acids targeting the SARS-CoV-2 main protease. Nat.Chem., 15, 2023
7N4W	Complex structure of ROTU4 with rotundine 分子名称: GLYCEROL, ROTU4, SULFATE ION, ... 著者 Kim, W, Zhang, Y. 登録日 2021-06-04 公開日 2022-06-29 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (1.64 Å) 主引用文献 Using fungible biosensors to evolve improved alkaloid biosyntheses. Nat.Chem.Biol., 18, 2022
2BY6	Is radiation damage dependent on the dose-rate used during macromolecular crystallography data collection 分子名称: BENZAMIDINE, CALCIUM ION, CATIONIC TRYPSIN, ... 著者 Leiros, H.-K.S, Timmins, J, Ravelli, R.B.G, McSweeney, S.M. 登録日 2005-07-29 公開日 2006-02-06 最終更新日 2021-08-04 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Is Radiation Damage Dependent on the Dose-Rate Used During Macromolecular Crystallography Data Collection? Acta Crystallogr.,Sect.D, 62, 2006
2BY7	Is radiation damage dependent on the dose-rate used during macromolecular crystallography data collection 分子名称: BENZAMIDINE, CALCIUM ION, CATIONIC TRYPSIN, ... 著者 Leiros, H.-K.S, Timmins, J, Ravelli, R.B.G, McSweeney, S.M. 登録日 2005-07-29 公開日 2006-02-06 最終更新日 2021-08-04 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Is Radiation Damage Dependent on the Dose-Rate Used During Macromolecular Crystallography Data Collection? Acta Crystallogr.,Sect.D, 62, 2006
2BY9	Is radiation damage dependent on the dose-rate used during macromolecular crystallography data collection 分子名称: BENZAMIDINE, CALCIUM ION, CATIONIC TRYPSIN, ... 著者 Leiros, H.-K.S, Timmins, J, Ravelli, R.B.G, McSweeney, S.M. 登録日 2005-07-29 公開日 2006-02-06 最終更新日 2021-08-04 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Is Radiation Damage Dependent on the Dose-Rate Used During Macromolecular Crystallography Data Collection? Acta Crystallogr.,Sect.D, 62, 2006
2BYA	Is radiation damage dependent on the dose-rate used during macromolecular crystallography data collection 分子名称: BENZAMIDINE, CALCIUM ION, CATIONIC TRYPSIN, ... 著者 Leiros, H.-K.S, Timmins, J, Ravelli, R.B.G, McSweeney, S.M. 登録日 2005-07-29 公開日 2006-02-06 最終更新日 2021-08-04 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Is Radiation Damage Dependent on the Dose-Rate Used During Macromolecular Crystallography Data Collection? Acta Crystallogr.,Sect.D, 62, 2006
2BY5	Is radiation damage dependent on the dose-rate used during macromolecular crystallography data collection 分子名称: BENZAMIDINE, CALCIUM ION, CATIONIC TRYPSIN, ... 著者 Leiros, H.-K.S, Timmins, J, Ravelli, R.B.G, McSweeney, S.M. 登録日 2005-07-29 公開日 2006-02-06 最終更新日 2021-08-04 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Is Radiation Damage Dependent on the Dose-Rate Used During Macromolecular Crystallography Data Collection? Acta Crystallogr.,Sect.D, 62, 2006
2BY8	Is radiation damage dependent on the dose-rate used during macromolecular crystallography data collection 分子名称: BENZAMIDINE, CALCIUM ION, CATIONIC TRYPSIN, ... 著者 Leiros, H.-K.S, Timmins, J, Ravelli, R.B.G, McSweeney, S.M. 登録日 2005-07-29 公開日 2006-02-06 最終更新日 2021-08-04 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Is Radiation Damage Dependent on the Dose-Rate Used During Macromolecular Crystallography Data Collection? Acta Crystallogr.,Sect.D, 62, 2006
2BLW	Trypsin after a high dose X-ray "Burn" 分子名称: BENZAMIDINE, CALCIUM ION, GLYCEROL, ... 著者 Nanao, M.H, Ravelli, R.B. 登録日 2005-03-08 公開日 2005-09-07 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Improving Radiation-Damage Substructures for Rip. Acta Crystallogr.,Sect.D, 61, 2005
8OY0	ATP phosphoribosyltransferase (HisZG ATPPRT) from Acinetobacter baumanii 分子名称: ATP phosphoribosyltransferase, ATP phosphoribosyltransferase regulatory subunit, GLYCEROL, ... 著者 Alphey, M.S, Read, B, da Silva, R.G. 登録日 2023-05-03 公開日 2023-11-29 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Crystal Structure, Steady-State, and Pre-Steady-State Kinetics of Acinetobacter baumannii ATP Phosphoribosyltransferase. Biochemistry, 63, 2024
2CMY	Crystal complex between bovine trypsin and Veronica hederifolia trypsin inhibitor 分子名称: CALCIUM ION, CATIONIC TRYPSIN, GLYCEROL, ... 著者 Conners, R, Yardley, J.L, Konarev, A, Shewry, P, Brady, R.L. 登録日 2006-05-16 公開日 2007-05-22 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 An Unusual Helix-Turn-Helix Protease Inhibitory Motif in a Novel Trypsin Inhibitor from Seeds of Veronica (Veronica Hederifolia L.). J.Biol.Chem., 282, 2007
2BLV	Trypsin before a high dose x-ray "burn" 分子名称: BENZAMIDINE, CALCIUM ION, GLYCEROL, ... 著者 Nanao, M.H, Ravelli, R.B. 登録日 2005-03-08 公開日 2005-09-07 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Improving Radiation-Damage Substructures for Rip. Acta Crystallogr.,Sect.D, 61, 2005
1SKU	E. coli Aspartate Transcarbamylase 240's Loop Mutant (K244N) 分子名称: Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, MALONATE ION, ... 著者 Alam, N, Stieglitz, K.A, Caban, M.D, Gourinath, S, Tsuruta, H, Kantrowitz, E.R. 登録日 2004-03-05 公開日 2004-03-30 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 240s Loop Interactions Stabilize the T State of Escherichia coli Aspartate Transcarbamoylase. J.Biol.Chem., 279, 2004
4WAJ	H. influenzae beta-carbonic anhydase variant P48S/A49P 分子名称: Carbonic anhydrase 2, SULFATE ION, ZINC ION 著者 Rowlett, R.S, Hoffmann, K.M. 登録日 2014-08-29 公開日 2014-12-31 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Allosteric Reversion of Haemophilus influenzae beta-Carbonic Anhydrase via a Proline Shift. Biochemistry, 54, 2015
4FC0	Crystal Structure of Human Kinase Domain of B-raf with a DFG-out Inhibitor 分子名称: 2-chloro-3-[(2-cyanopropan-2-yl)oxy]-N-{5-[{2-[(cyclopropylcarbonyl)amino][1,3]thiazolo[5,4-b]pyridin-5-yl}(methyl)amino]-2-fluorophenyl}benzamide, Serine/threonine-protein kinase B-raf 著者 Yano, J.K, Aertgeerts, K. 登録日 2012-05-23 公開日 2014-01-08 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Design and synthesis of novel DFG-out RAF/vascular endothelial growth factor receptor 2 (VEGFR2) inhibitors: 3. Evaluation of 5-amino-linked thiazolo[5,4-d]pyrimidine and thiazolo[5,4-b]pyridine derivatives. Bioorg.Med.Chem., 20, 2012
6OEZ	Crystal structure of Trypanothione Reductase from Trypanosoma brucei in complex with inhibitor (+)-N-(Cyclobutylmethyl)-3-{5-[1-(pyrrolidin-1-yl)cyclohexyl]-2-(1-{[(2S)-pyrro-lidin-2-yl]methyl}-1H-indol-5-yl)-1,3-thiazol-4-yl}prop-2-yn-1-amine 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, FLAVIN-ADENINE DINUCLEOTIDE, N-(cyclobutylmethyl)-3-{5-[1-(pyrrolidin-1-yl)cyclohexyl]-2-(1-{[(2S)-pyrrolidin-2-yl]methyl}-1H-indol-5-yl)-1,3-thiazol-4-yl}prop-2-yn-1-amine, ... 著者 Halgas, O, De Gasparo, R, Harangozo, D, Krauth-Siegel, R.L, Diederich, F, Pai, E.F. 登録日 2019-03-28 公開日 2019-07-31 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Targeting a Large Active Site: Structure-Based Design of Nanomolar Inhibitors of Trypanosoma brucei Trypanothione Reductase. Chemistry, 25, 2019
2YBS	JMJD2A COMPLEXED WITH S-2-HYDROXYGLUTARATE AND HISTONE H3K36me3 PEPTIDE (30-41) 分子名称: (2S)-2-HYDROXYPENTANEDIOIC ACID, GLYCEROL, HISTONE H3.1T, ... 著者 Chowdhury, R, Schofield, C.J. 登録日 2011-03-10 公開日 2011-03-30 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.32 Å) 主引用文献 The oncometabolite 2-hydroxyglutarate inhibits histone lysine demethylases. EMBO Rep., 12, 2011
6PRD	S. aureus dihydrofolate reductase co-crystallized with para-methoxyphenyl-dimethyoxydihydropthalazine inhibitor and NADP(H) 分子名称: 3-{5-[(2,4-diaminopyrimidin-5-yl)methyl]-2,3-dimethoxyphenyl}-1-[(1S)-6,7-dimethoxy-1-(4-methoxyphenyl)-3,4-dihydrophthalazin-2(1H)-yl]propan-1-one, Dihydrofolate reductase, GLYCEROL, ... 著者 Bourne, C.R, Thomas, L.M. 登録日 2019-07-10 公開日 2020-06-17 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Inhibitor design to target a unique feature in the folate pocket of Staphylococcus aureus dihydrofolate reductase. Eur.J.Med.Chem., 200, 2020
3NOM	Crystal Structure of Zymomonas mobilis Glutaminyl Cyclase (monoclinic form) 分子名称: CALCIUM ION, GLYCEROL, Glutamine cyclotransferase, ... 著者 Parthier, C, Carrillo, D.R, Stubbs, M.T. 登録日 2010-06-25 公開日 2010-11-03 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Kinetic and structural characterization of bacterial glutaminyl cyclases from Zymomonas mobilis and Myxococcus xanthus Biol.Chem., 391, 2010

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