PDB: 66478 件ウェブページステータス検索Chemie searchBIRD

---

4U9W	Crystal Structure of NatD bound to H4/H2A peptide and CoA 分子名称: COENZYME A, GLYCEROL, Histone H4/H2A N-terminus, ... 著者 Magin, R.S, Liszczak, G.P, Marmorstein, R. 登録日 2014-08-06 公開日 2015-01-28 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.49 Å) 主引用文献 The Molecular Basis for Histone H4- and H2A-Specific Amino-Terminal Acetylation by NatD. Structure, 23, 2015
2MCW	Solid-state NMR structure of piscidin 3 in aligned 3:1 phosphatidylcholine/phosphoglycerol lipid bilayers 分子名称: Piscidin-3 著者 Fu, R, Tian, Y, Perrin Jr, B.S, Grant, C.V, Pastor, R.W, Cotten, M.L. 登録日 2013-08-27 公開日 2014-01-22 最終更新日 2014-03-19 実験手法 SOLID-STATE NMR 主引用文献 High-resolution structures and orientations of antimicrobial peptides piscidin 1 and piscidin 3 in fluid bilayers reveal tilting, kinking, and bilayer immersion. J.Am.Chem.Soc., 136, 2014
3VV6	Crystal Structure of beta secetase in complex with 2-amino-3-methyl-6-((1S, 2R)-2-phenylcyclopropyl)pyrimidin-4(3H)-one 分子名称: 2-amino-3-methyl-6-[(1S,2R)-2-phenylcyclopropyl]pyrimidin-4(3H)-one, Beta-secretase 1, GLYCEROL, ... 著者 Yonezawa, S, Yamamoto, T, Yamakawa, H, Muto, C, Hosono, M, Hattori, K, Higashino, K, Sakagami, M, Togame, H, Tanaka, Y, Nakano, T, Takemoto, H, Arisawa, M, Shuto, S. 登録日 2012-07-17 公開日 2012-10-24 最終更新日 2017-11-22 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Conformational restriction approach to beta-secretase (BACE1) inhibitors: effect of a cyclopropane ring to induce an alternative binding mode J.Med.Chem., 55, 2012
2MCV	Solid-state NMR structure of piscidin 1 in aligned 1:1 phosphatidylethanolamine/phosphoglycerol lipid bilayers 分子名称: Moronecidin 著者 Fu, R, Tian, Y, Perrin Jr, B.S, Grant, C.V, Hayden, R.M, Pastor, R.W, Cotten, M.L. 登録日 2013-08-27 公開日 2014-01-22 最終更新日 2014-03-19 実験手法 SOLID-STATE NMR 主引用文献 High-resolution structures and orientations of antimicrobial peptides piscidin 1 and piscidin 3 in fluid bilayers reveal tilting, kinking, and bilayer immersion. J.Am.Chem.Soc., 136, 2014
3VG6	Barium derivative of human LFABP 分子名称: BARIUM ION, Fatty acid-binding protein, liver, ... 著者 Sharma, A, Yogavel, M, Sharma, A. 登録日 2011-08-03 公開日 2012-06-20 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.22 Å) 主引用文献 Utility of anion and cation combinations for phasing of protein structures. J.Struct.Funct.Genom., 13, 2012
3VG2	Iodide derivative of human LFABP 分子名称: Fatty acid-binding protein, liver, IODIDE ION, ... 著者 Sharma, A, Yogavel, M, Sharma, A. 登録日 2011-08-03 公開日 2012-06-20 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Utility of anion and cation combinations for phasing of protein structures. J.Struct.Funct.Genom., 13, 2012
3VZN	Crystal structure of the Bacillus circulans endo-beta-(1,4)-xylanase (BcX) N35E mutant with Glu78 covalently bonded to 2-deoxy-2-fluoro-xylobiose 分子名称: Endo-1,4-beta-xylanase, SULFATE ION, beta-D-xylopyranose-(1-4)-1,5-anhydro-2-deoxy-2-fluoro-D-xylitol 著者 Ludwiczek, M.L, D'Angelo, I, Yalloway, G.N, Okon, M, Nielsen, J.E, Strynadka, N.C, Withers, S.G, McIntosh, L.P. 登録日 2012-10-15 公開日 2013-05-08 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.67 Å) 主引用文献 Strategies for modulating the pH-dependent activity of a family 11 glycoside hydrolase Biochemistry, 52, 2013
3VMO	Crystal structure of dextranase from Streptococcus mutans in complex with isomaltotriose 分子名称: Dextranase, PHOSPHATE ION, alpha-D-glucopyranose-(1-6)-alpha-D-glucopyranose, ... 著者 Suzuki, N, Fujimoto, Z, Kim, Y.M, Momma, M, Okuyama, M, Mori, H, Funane, K, Kimura, A. 登録日 2011-12-14 公開日 2012-02-15 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural elucidation of dextran degradation mechanism by streptococcus mutans dextranase belonging to glycoside hydrolase family 66 J.Biol.Chem., 287, 2012
3MIS	I-MsoI re-designed for altered DNA cleavage specificity (-8G) 分子名称: CALCIUM ION, DNA (5'-D(*CP*GP*GP*AP*GP*CP*TP*GP*TP*CP*TP*CP*AP*CP*GP*AP*CP*GP*TP*CP*CP*TP*GP*C)-3'), DNA (5'-D(*GP*CP*AP*GP*GP*AP*CP*GP*TP*CP*GP*TP*GP*AP*GP*AP*CP*AP*GP*CP*TP*CP*CP*G)-3'), ... 著者 Taylor, G.K, Stoddard, B.L. 登録日 2010-04-12 公開日 2010-05-19 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Computational reprogramming of homing endonuclease specificity at multiple adjacent base pairs. Nucleic Acids Res., 38, 2010
3VV8	Crystal structure of beta secetase in complex with 2-amino-3-methyl-6-((1S,2R)-2-(3'-methylbiphenyl-4-yl)cyclopropyl)pyrimidin-4(3H)-one 分子名称: 2-amino-3-methyl-6-[(1S,2R)-2-(3'-methylbiphenyl-4-yl)cyclopropyl]pyrimidin-4(3H)-one, Beta-secretase 1, GLYCEROL 著者 Yonezawa, S, Yamamoto, T, Yamakawa, H, Muto, C, Hosono, M, Hattori, K, Higashino, K, Sakagami, M, Togame, H, Tanaka, Y, Nakano, T, Takemoto, H, Arisawa, M, Shuto, S. 登録日 2012-07-17 公開日 2012-10-24 最終更新日 2013-09-04 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Conformational restriction approach to beta-secretase (BACE1) inhibitors: effect of a cyclopropane ring to induce an alternative binding mode. J.Med.Chem., 55, 2012
2MI5	Structure of insect-specific sodium channel toxin mu-Dc1a 分子名称: Mu-diguetoxin-Dc1a 著者 Bende, N.S, Mobli, M, King, G.F. 登録日 2013-12-08 公開日 2014-07-23 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 A distinct sodium channel voltage-sensor locus determines insect selectivity of the spider toxin Dc1a. Nat Commun, 5, 2014
2MCX	Solid-state NMR structure of piscidin 3 in aligned 1:1 phosphatidylethanolamine/phosphoglycerol lipid bilayers 分子名称: Piscidin-3 著者 Fu, R, Tian, Y, Perrin Jr, B.S, Grant, C.V, Wieczorek, W.E, Pastor, R.W, Cotten, M.L. 登録日 2013-08-27 公開日 2014-01-22 最終更新日 2021-08-18 実験手法 SOLID-STATE NMR 主引用文献 High-resolution structures and orientations of antimicrobial peptides piscidin 1 and piscidin 3 in fluid bilayers reveal tilting, kinking, and bilayer immersion. J.Am.Chem.Soc., 136, 2014
3VG5	Barium derivative of human LFABP 分子名称: BARIUM ION, Fatty acid-binding protein, liver, ... 著者 Sharma, A, Yogavel, M, Sharma, A. 登録日 2011-08-03 公開日 2012-06-20 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Utility of anion and cation combinations for phasing of protein structures. J.Struct.Funct.Genom., 13, 2012
3W1F	Crystal structure of Human MPS1 catalytic domain in complex with 5-(5-ethoxy-6-(1-methyl-1H-pyrazol-4-yl)-1H-indazol-3-yl)-2-methylbenzenesulfonamide 分子名称: 5-[5-ethoxy-6-(1-methyl-1H-pyrazol-4-yl)-1H-indazol-3-yl]-2-methylbenzenesulfonamide, Dual specificity protein kinase TTK 著者 Kusakabe, K, Ide, N, Daigo, Y, Tachibana, Y, Itoh, T, Yamamoto, T, Hashizume, H, Hato, Y, Higashino, K, Okano, Y, Sato, Y, Inoue, M, Iguchi, M, Kanazawa, T, Ishioka, Y, Dohi, K, Kido, Y, Sakamoto, S, Yasuo, K, Maeda, M, Higaki, M, Ueda, K, Yoshizawa, H, Baba, Y, Shiota, T, Murai, H, Nakamura, Y. 登録日 2012-11-14 公開日 2013-06-26 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Indazole-based potent and cell-active Mps1 kinase inhibitors: rational design from pan-kinase inhibitor anthrapyrazolone (SP600125) J.Med.Chem., 56, 2013
3VNA	Structural insights into small RNA sorting and mRNA binding by Arabidopsis Ago Mid domains 分子名称: Protein argonaute 1, SULFATE ION 著者 Yuan, Y.A, Zha, X. 登録日 2012-01-11 公開日 2012-10-10 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural insights into small RNA sorting and mRNA target binding by Arabidopsis Argonaute Mid domains Febs Lett., 586, 2012
3VID	Crystal structure of human VEGFR2 kinase domain with Compound A. 分子名称: 4,5,6,11-tetrahydro-1H-pyrazolo[4',3':6,7]cyclohepta[1,2-b]indole, Vascular endothelial growth factor receptor 2 著者 Iwata, H, Oki, H, Okada, K, Takagi, T, Tawada, M, Miyazaki, Y, Imamura, S, Hori, A, Hixon, M.S, Kimura, H, Miki, H. 登録日 2011-09-29 公開日 2012-08-15 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 A Back-to-Front Fragment-Based Drug Design Search Strategy Targeting the DFG-Out Pocket of Protein Tyrosine Kinases. ACS MED.CHEM.LETT., 3, 2012
2MCU	Solid-state NMR structure of piscidin 1 in aligned 3:1 phosphatidylcholine/phosphoglycerol lipid bilayers 分子名称: Moronecidin 著者 Fu, R, Tian, Y, Perrin Jr, B.S, Grant, C.V, Pastor, R.W, Cotten, M.L. 登録日 2013-08-27 公開日 2014-01-22 最終更新日 2014-03-19 実験手法 SOLID-STATE NMR 主引用文献 High-resolution structures and orientations of antimicrobial peptides piscidin 1 and piscidin 3 in fluid bilayers reveal tilting, kinking, and bilayer immersion. J.Am.Chem.Soc., 136, 2014
4V11	Structure of Synaptotagmin-1 with SV2A peptide phosphorylated at Thr84 分子名称: CALCIUM ION, GLYCEROL, SYNAPTIC VESICLE GLYCOPROTEIN 2A, ... 著者 Zhang, N, Gordon, S.L, Fritsch, M.J, Esoof, N, Campbell, D, Gourlay, R, Velupillai, S, Macartney, T, Peggie, M, vanAalten, D.M.F, Cousin, M.A, Alessi, D.R. 登録日 2014-09-22 公開日 2015-02-25 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Phosphorylation of Synaptic Vesicle Protein 2A at Thr84 by Casein Kinase 1 Family Kinases Controls the Specific Retrieval of Synaptotagmin-1. J.Neurosci., 35, 2015
3VZM	Crystal structure of the Bacillus circulans endo-beta-(1,4)-xylanase (BcX) E172H mutant with Glu78 covalently bonded to 2-deoxy-2-fluoro-xylobiose 分子名称: Endo-1,4-beta-xylanase, beta-D-xylopyranose-(1-4)-1,5-anhydro-2-deoxy-2-fluoro-D-xylitol 著者 Ludwiczek, M.L, D'Angelo, I, Yalloway, G.N, Okon, M, Nielsen, J.E, Strynadka, N.C, Withers, S.G, McIntosh, L.P. 登録日 2012-10-15 公開日 2013-05-08 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.86 Å) 主引用文献 Strategies for modulating the pH-dependent activity of a family 11 glycoside hydrolase Biochemistry, 52, 2013
3VV7	Crystal Structure of beta secetase in complex with 2-amino-6-((1S,2R)-2-(3'-methoxybiphenyl-3-yl)cyclopropyl)-3-methylpyrimidin-4(3H)-one 分子名称: 2-amino-6-[(1S,2R)-2-(3'-methoxybiphenyl-3-yl)cyclopropyl]-3-methylpyrimidin-4(3H)-one, Beta-secretase 1, GLYCEROL, ... 著者 Yonezawa, S, Yamamoto, T, Yamakawa, H, Muto, C, Hosono, M, Hattori, K, Higashino, K, Sakagami, M, Togame, H, Tanaka, Y, Nakano, T, Takemoto, H, Arisawa, M, Shuto, S. 登録日 2012-07-17 公開日 2012-10-24 最終更新日 2013-09-04 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Conformational restriction approach to beta-secretase (BACE1) inhibitors: effect of a cyclopropane ring to induce an alternative binding mode. J.Med.Chem., 55, 2012
3VZK	Crystal structure of the Bacillus circulans endo-beta-(1,4)-xylanase (BcX) N35E mutant 分子名称: Endo-1,4-beta-xylanase, SULFATE ION 著者 Ludwiczek, M.L, D'Angelo, I, Yalloway, G.N, Okon, M, Nielsen, J.E, Strynadka, N.C, Withers, S.G, McIntosh, L.P. 登録日 2012-10-14 公開日 2013-05-08 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Strategies for modulating the pH-dependent activity of a family 11 glycoside hydrolase Biochemistry, 52, 2013
3VZO	Crystal structure of the Bacillus circulans endo-beta-(1,4)-xylanase (BcX) N35H mutant with Glu78 covalently bonded to 2-deoxy-2-fluoro-xylobiose 分子名称: Endo-1,4-beta-xylanase, SULFATE ION, beta-D-xylopyranose-(1-4)-1,5-anhydro-2-deoxy-2-fluoro-D-xylitol 著者 Ludwiczek, M.L, D'Angelo, I, Yalloway, G.N, Okon, M, Nielsen, J.E, Strynadka, N.C, Withers, S.G, McIntosh, L.P. 登録日 2012-10-15 公開日 2013-05-08 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 Strategies for modulating the pH-dependent activity of a family 11 glycoside hydrolase Biochemistry, 52, 2013
3VZV	Crystal structure of human mdm2 with a dihydroimidazothiazole inhibitor 分子名称: 1-{[(5R,6S)-5,6-bis(4-chlorophenyl)-6-methyl-3-(propan-2-yl)-5,6-dihydroimidazo[2,1-b][1,3]thiazol-2-yl]carbonyl}-N,N-dimethyl-L-prolinamide, E3 ubiquitin-protein ligase Mdm2 著者 Shimizu, H, Katakura, S, Miyazaki, M, Naito, H, Sugimoto, Y, Kawato, H, Okayama, T, Soga, T. 登録日 2012-10-16 公開日 2013-02-06 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Lead optimization of novel p53-MDM2 interaction inhibitors possessing dihydroimidazothiazole scaffold Bioorg.Med.Chem.Lett., 23, 2013
2M4J	40-residue beta-amyloid fibril derived from Alzheimer's disease brain 分子名称: Amyloid beta A4 protein 著者 Lu, J, Qiang, W, Meredith, S.C, Yau, W, Schweiters, C.D, Tycko, R. 登録日 2013-02-05 公開日 2013-09-25 最終更新日 2024-05-15 実験手法 SOLID-STATE NMR 主引用文献 Molecular Structure of beta-Amyloid Fibrils in Alzheimer's Disease Brain Tissue. Cell(Cambridge,Mass.), 154, 2013
3WWO	S-selective hydroxynitrile lyase from Baliospermum montanum (apo1) 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, (S)-hydroxynitrile lyase, CALCIUM ION 著者 Nakano, S, Dadashipour, M, Asano, Y. 登録日 2014-06-23 公開日 2014-10-22 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Structural and functional analysis of hydroxynitrile lyase from Baliospermum montanum with crystal structure, molecular dynamics and enzyme kinetics Biochim.Biophys.Acta, 1844, 2014

<307308309310311312313314315316317318319320321322>