PDB: 42250 件ウェブページステータス検索Chemie searchBIRD

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4V52	Crystal structure of the bacterial ribosome from Escherichia coli in complex with neomycin. 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Borovinskaya, M.A, Pai, R.D, Zhang, W, Schuwirth, B.-S, Holton, J.M, Hirokawa, G, Kaji, H, Kaji, A, Cate, J.H.D. 登録日 2007-06-15 公開日 2014-07-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.21 Å) 主引用文献 Structural basis for aminoglycoside inhibition of bacterial ribosome recycling. Nat.Struct.Mol.Biol., 14, 2007
4V7W	Structure of the Thermus thermophilus ribosome complexed with chloramphenicol. 分子名称: 16S rRNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Bulkley, D.P, Innis, C.A, Blaha, G, Steitz, T.A. 登録日 2010-08-16 公開日 2014-07-09 最終更新日 2024-11-27 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Revisiting the structures of several antibiotics bound to the bacterial ribosome. Proc.Natl.Acad.Sci.USA, 107, 2010
4V8C	Crystal structure analysis of ribosomal decoding (near-cognate tRNA-leu complex with paromomycin). 分子名称: 16S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... 著者 Jenner, L, Demeshkina, N, Yusupov, M, Yusupova, G. 登録日 2011-12-07 公開日 2014-07-09 最終更新日 2024-11-27 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 A new understanding of the decoding principle on the ribosome. Nature, 484, 2012
4V4H	Crystal structure of the bacterial ribosome from Escherichia coli in complex with the antibiotic kasugamyin at 3.5A resolution. 分子名称: (1S,2R,3S,4R,5S,6S)-2,3,4,5,6-PENTAHYDROXYCYCLOHEXYL 2-AMINO-4-{[CARBOXY(IMINO)METHYL]AMINO}-2,3,4,6-TETRADEOXY-ALPHA-D-ARABINO-HEXOPYRANOSIDE, 16S RIBOSOMAL RNA, 23S RIBOSOMAL RNA, ... 著者 Schuwirth, B.S, Vila-Sanjurjo, A, Cate, J.H.D. 登録日 2006-08-04 公開日 2014-07-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.46 Å) 主引用文献 Structural analysis of kasugamycin inhibition of translation. Nat.Struct.Mol.Biol., 13, 2006
4W2I	Crystal structure of the Thermus thermophilus 70S ribosome in complex with negamycin, mRNA and three deacylated tRNAs in the A, P and E sites 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ... 著者 Polikanov, Y.S, Szal, T, Jiang, F, Gupta, P, Matsuda, R, Shiozuka, M, Steitz, T.A, Vazquez-Laslop, N, Mankin, A.S. 登録日 2014-09-12 公開日 2014-10-15 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Negamycin Interferes with Decoding and Translocation by Simultaneous Interaction with rRNA and tRNA. Mol.Cell, 56, 2014
4V57	Crystal structure of the bacterial ribosome from Escherichia coli in complex with spectinomycin and neomycin. 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Borovinskaya, M.A, Shoji, S, Holton, J.M, Fredrick, K, Cate, J.H.D. 登録日 2007-07-21 公開日 2014-07-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 A steric block in translation caused by the antibiotic spectinomycin. Acs Chem.Biol., 2, 2007
4V4G	Crystal structure of five 70s ribosomes from Escherichia Coli in complex with protein Y. 分子名称: 16S ribosomal RNA, 23S RIBOSOMAL RNA, 30S ribosomal protein S10, ... 著者 Vila-Sanjurjo, A, Schuwirth, B.S, Hau, C.W, Cate, J.H. 登録日 2004-10-06 公開日 2014-07-09 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (11.5 Å) 主引用文献 Structural basis for the control of translation initiation during stress. Nat.Struct.Mol.Biol., 11, 2004
4V6C	Crystal structure of the E. coli 70S ribosome in an intermediate state of ratcheting 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Zhang, W, Dunkle, J.A, Cate, J.H.D. 登録日 2009-06-27 公開日 2014-07-09 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (3.19 Å) 主引用文献 Structures of the ribosome in intermediate States of ratcheting. Science, 325, 2009
4V7V	Crystal structure of the E. coli ribosome bound to clindamycin. 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Dunkle, J.A, Xiong, L, Mankin, A.S, Cate, J.H.D. 登録日 2010-08-16 公開日 2014-07-09 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (3.2891 Å) 主引用文献 Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action. Proc.Natl.Acad.Sci.USA, 107, 2010
4V8G	Crystal structure of RMF bound to the 70S ribosome. 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ... 著者 Polikanov, Y.S, Blaha, G.M, Steitz, T.A. 登録日 2011-12-11 公開日 2014-07-09 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 How hibernation factors RMF, HPF, and YfiA turn off protein synthesis. Science, 336, 2012
4V90	Thermus thermophilus Ribosome 分子名称: 16S RIBOSOMAL RNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... 著者 Chen, Y, Feng, S, Kumar, V, Ero, R, Gao, Y.G. 登録日 2014-02-22 公開日 2014-07-09 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (2.95 Å) 主引用文献 Structure of EF-G-ribosome complex in a pretranslocation state. Nat. Struct. Mol. Biol., 20, 2013
4V9D	Structures of the bacterial ribosome in classical and hybrid states of tRNA binding 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Dunkle, J.A, Wang, L, Feldman, M.B, Pulk, A, Chen, V.B, Kapral, G.J, Noeske, J, Richardson, J.S, Blanchard, S.C, Cate, J.H.D. 登録日 2012-07-31 公開日 2014-07-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structures of the bacterial ribosome in classical and hybrid states of tRNA binding. Science, 332, 2011
4W2H	Crystal structure of the Thermus thermophilus 70S ribosome in complex with pactamycin (co-crystallized), mRNA and deacylated tRNA in the P site 分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ... 著者 Polikanov, Y.S, Osterman, I.A, Szal, T, Tashlitsky, V.N, Serebryakova, M.V, Kusochek, P, Bulkley, D, Malanicheva, I.A, Efimenko, T.A, Efremenkova, O.V, Konevega, A.L, Shaw, K.J, Bogdanov, A.A, Rodnina, M.V, Dontsova, O.A, Mankin, A.S, Steitz, T.A, Sergiev, P.V. 登録日 2014-09-12 公開日 2014-10-15 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Amicoumacin a inhibits translation by stabilizing mRNA interaction with the ribosome. Mol.Cell, 56, 2014
4V54	Crystal structure of the bacterial ribosome from Escherichia coli in complex with ribosome recycling factor (RRF). 分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... 著者 Borovinskaya, M.A, Pai, R.D, Zhang, W, Schuwirth, B.-S, Holton, J.M, Hirokawa, G, Kaji, H, Kaji, A, Cate, J.H.D. 登録日 2007-06-16 公開日 2014-07-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Structural basis for aminoglycoside inhibition of bacterial ribosome recycling. Nat.Struct.Mol.Biol., 14, 2007
4V9B	Crystal Structure of the 70S ribosome with tigecycline. 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ... 著者 Jenner, L, Yusupov, M, Yusupova, G. 登録日 2012-07-18 公開日 2014-07-09 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structural basis for potent inhibitory activity of the antibiotic tigecycline during protein synthesis. Proc.Natl.Acad.Sci.USA, 110, 2013
4V63	Structural basis for translation termination on the 70S ribosome. 分子名称: 16S RRNA, 23S RRNA, 30S ribosomal protein S10, ... 著者 Laurberg, M, Asahara, H, Korostelev, A, Zhu, J, Trakhanov, S, Noller, H.F. 登録日 2008-05-16 公開日 2014-07-09 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (3.207 Å) 主引用文献 Structural basis for translation termination on the 70S ribosome Nature, 454, 2008
4V7L	The structures of viomycin bound to the 70S ribosome. 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Stanley, R.E, Blaha, G. 登録日 2009-11-12 公開日 2014-07-09 最終更新日 2025-03-26 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The structures of the anti-tuberculosis antibiotics viomycin and capreomycin bound to the 70S ribosome. Nat.Struct.Mol.Biol., 17, 2010
4V87	Crystal structure analysis of ribosomal decoding. 分子名称: 16S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... 著者 Demeshkina, N, Jenner, L, Yusupov, M, Yusupova, G. 登録日 2011-09-20 公開日 2014-07-09 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 A new understanding of the decoding principle on the ribosome. Nature, 484, 2012
4V9Q	Crystal Structure of Blasticidin S Bound to Thermus Thermophilus 70S Ribosome. 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Svidritskiy, E, Ling, C, Ermolenko, D.N, Korostelev, A.A. 登録日 2013-06-12 公開日 2014-07-09 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Blasticidin S inhibits translation by trapping deformed tRNA on the ribosome. Proc.Natl.Acad.Sci.USA, 110, 2013
4V4Q	Crystal structure of the bacterial ribosome from Escherichia coli at 3.5 A resolution. 分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... 著者 Schuwirth, B.S, Borovinskaya, M.A, Hau, C.W, Zhang, W, Vila-Sanjurjo, A, Holton, J.M, Cate, J.H.D. 登録日 2005-08-30 公開日 2014-07-09 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.46 Å) 主引用文献 Structures of the bacterial ribosome at 3.5 A resolution. Science, 310, 2005
4V5E	Insights into translational termination from the structure of RF2 bound to the ribosome 分子名称: 16S ribosomal RNA, 23S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, ... 著者 Weixlbaumer, A, Jin, H, Neubauer, C, Voorhees, R.M, Petry, S, Kelley, A.C, Ramakrishnan, V. 登録日 2009-04-30 公開日 2014-07-09 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (3.45 Å) 主引用文献 Insights Into Translational Termination from the Structure of Rf2 Bound to the Ribosome. Science, 322, 2008
8CEH	Translocation intermediate 4 (TI-4) of 80S S. cerevisiae ribosome with ligands and eEF2 in the presence of sordarin 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... 著者 Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G. 登録日 2023-02-01 公開日 2023-09-20 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.05 Å) 主引用文献 mRNA reading frame maintenance during eukaryotic ribosome translocation. Nature, 625, 2024
6OM0	Human ribosome nascent chain complex (PCSK9-RNC) stalled by a drug-like molecule with AP and PE tRNAs 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... 著者 Li, W, Cate, J.H.D. 登録日 2019-04-17 公開日 2019-06-19 最終更新日 2024-11-13 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Structural basis for selective stalling of human ribosome nascent chain complexes by a drug-like molecule. Nat.Struct.Mol.Biol., 26, 2019
8BN3	Yeast 80S, ES7s delta, eIF5A, Stm1 containing 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, ... 著者 Dimitrova-Paternoga, L, Paternoga, H, Wilson, D.N. 登録日 2022-11-12 公開日 2024-01-10 最終更新日 2024-10-16 実験手法 ELECTRON MICROSCOPY (2.4 Å) 主引用文献 Evolving precision: rRNA expansion segment 7S modulates translation velocity and accuracy in eukaryal ribosomes. Nucleic Acids Res., 52, 2024
8C3A	Crystal structure of ailanthone bound to the Candida albicans 80S ribosome 分子名称: 18S, 25S, 3-O-acetyl-2-O-(3-O-acetyl-6-deoxy-beta-D-glucopyranosyl)-6-deoxy-1-O-{[(2R,2'S,3a'R,4''S,5''R,6'S,7a'S)-5''-methyl-4''-{[(2E)-3-phenylprop-2-enoyl]oxy}decahydrodispiro[oxirane-2,3'-[1]benzofuran-2',2''-pyran]-6'-yl]carbonyl}-beta-D-glucopyranose, ... 著者 Kolosova, O, Zgadzay, Y, Yusupov, M. 登録日 2022-12-23 公開日 2024-01-10 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 New crystal system to promote screening for new eukaryotic inhibitors To Be Published

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