PDB: 1143 件ウェブページステータス検索Chemie searchBIRD

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5COX	UNINHIBITED MOUSE CYCLOOXYGENASE-2 (PROSTAGLANDIN SYNTHASE-2) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CYCLOOXYGENASE-2, PROTOPORPHYRIN IX CONTAINING FE 著者 Kurumbail, R, Stallings, W. 登録日 1996-12-18 公開日 1997-12-24 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents. Nature, 384, 1996
6LP1	Crystal structure of acetate:succinate CoA transferase (ASCT) from Trypanosoma brucei. 分子名称: CALCIUM ION, GLYCEROL, Succinyl-CoA:3-ketoacid-coenzyme A transferase 著者 Mochizuki, K, Inaoka, D.K, Shiba, T, Fukuda, K, Kurasawa, H, Mazet, M, Millerioux, Y, Bringaud, F, Boshart, M, Balogun, E.O, Harada, S, Hirayama, K, Kita, K. 登録日 2020-01-08 公開日 2020-10-07 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 The ASCT/SCS cycle fuels mitochondrial ATP and acetate production in Trypanosoma brucei. Biochim Biophys Acta Bioenerg, 1861, 2020
4COX	CYCLOOXYGENASE-2 (PROSTAGLANDIN SYNTHASE-2) COMPLEXED WITH A NON-SELECTIVE INHIBITOR, INDOMETHACIN 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CYCLOOXYGENASE-2, INDOMETHACIN, ... 著者 Kurumbail, R, Stallings, W. 登録日 1996-12-18 公開日 1997-12-24 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents. Nature, 384, 1996
3N9J	Structure of human Glutathione Transferase Pi class in complex with Ethacraplatin 分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, CHLORIDE ION, ... 著者 Parker, L.J, Parker, M.W. 登録日 2010-05-30 公開日 2011-05-11 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 Studies of glutathione transferase P1-1 bound to a platinum(IV)-based anticancer compound reveal the molecular basis of its activation. To be Published
8PPP	Amide bond synthetase from Streptomyces hindustanus K492H mutant in complex with AMP-CPP 分子名称: DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, Fatty-acyl-CoA synthase 著者 Tang, Q, Grogan, G. 登録日 2023-07-07 公開日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.57 Å) 主引用文献 Broad Spectrum Enantioselective Amide Bond Synthetase from Streptoalloteichus hindustanus. Acs Catalysis, 14, 2024
3PGH	CYCLOOXYGENASE-2 (PROSTAGLANDIN SYNTHASE-2) COMPLEXED WITH A NON-SELECTIVE INHIBITOR, FLURBIPROFEN 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CYCLOOXYGENASE-2, FLURBIPROFEN, ... 著者 Kurumbail, R, Stallings, W. 登録日 1996-12-18 公開日 1997-12-24 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents. Nature, 384, 1996
5Y08	Solution structure of the apo doublet acyl carrier protein from prodigiosin biosynthesis 分子名称: 4-hydroxy-2,2'-bipyrrole-5-methanol synthase PigH 著者 Wattana-amorn, P. 登録日 2017-07-15 公開日 2018-12-12 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Solution Structure and Conformational Dynamics of a Doublet Acyl Carrier Protein from Prodigiosin Biosynthesis. Biochemistry, 2021
4X91	Crystal structure of Lysosomal Phospholipase A2 in complex with Isopropyl dodec-11-enylfluorophosphonate (IDFP) 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... 著者 Glukhova, A, Tesmer, J.J.G. 登録日 2014-12-11 公開日 2015-03-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure and function of lysosomal phospholipase A2 and lecithin:cholesterol acyltransferase. Nat Commun, 6, 2015
4X94	Crystal structure of Lysosomal Phospholipase A2 crystallized in the presence of methyl arachidonyl fluorophosphonate (hexagonal form) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Group XV phospholipase A2, ... 著者 Glukhova, A, Tesmer, J.J.G. 登録日 2014-12-11 公開日 2015-03-11 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structure and function of lysosomal phospholipase A2 and lecithin:cholesterol acyltransferase. Nat Commun, 6, 2015
4X90	Crystal structure of Lysosomal Phospholipase A2 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... 著者 Glukhova, A, Tesmer, J.J.G. 登録日 2014-12-11 公開日 2015-03-11 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Structure and function of lysosomal phospholipase A2 and lecithin:cholesterol acyltransferase. Nat Commun, 6, 2015
4X93	Crystal structure of Lysosomal Phospholipase A2 crystallized in the presence of methyl arachidonyl fluorophosphonate (tetragonal form) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... 著者 Glukhova, A, Tesmer, J.J.G. 登録日 2014-12-11 公開日 2015-03-25 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structure and function of lysosomal phospholipase A2 and lecithin:cholesterol acyltransferase. Nat Commun, 6, 2015
5CSL	Crystal structure of the 500 kD yeast acetyl-CoA carboxylase holoenzyme dimer 分子名称: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Acetyl-CoA carboxylase, COENZYME A 著者 Wei, J, Tong, L. 登録日 2015-07-23 公開日 2015-10-28 最終更新日 2022-03-23 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Crystal structure of the 500-kDa yeast acetyl-CoA carboxylase holoenzyme dimer. Nature, 526, 2015
5CSK	Crystal structure of yeast acetyl-CoA carboxylase, unbiotinylated 分子名称: Acetyl-CoA carboxylase 著者 Wei, J, Tong, L. 登録日 2015-07-23 公開日 2015-10-28 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Crystal structure of the 500-kDa yeast acetyl-CoA carboxylase holoenzyme dimer. Nature, 526, 2015
1P45	Targeting tuberculosis and malaria through inhibition of enoyl reductase: compound activity and structural data 分子名称: Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE, TRICLOSAN 著者 Kuo, M.R, Morbidoni, H.R, Alland, D, Sneddon, S.F, Gourlie, B.B, Staveski, M.M, Leonard, M, Gregory, J.S, Janjigian, A.D, Yee, C, Musser, J.M, Kreiswirth, B.N, Iwamoto, H, Perozzo, R, Jacobs Jr, W.R, Sacchettini, J.C, Fidock, D.A, TB Structural Genomics Consortium (TBSGC) 登録日 2003-04-21 公開日 2003-09-16 最終更新日 2019-07-24 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Targeting tuberculosis and malaria through inhibition of Enoyl reductase: compound activity and structural data. J.Biol.Chem., 278, 2003
3WXZ	The structure of the I375F mutant of CsyB 分子名称: Putative uncharacterized protein csyB 著者 Mori, T, Yang, D, Matsui, T, Morita, H, Fujii, I, Abe, I. 登録日 2014-08-13 公開日 2015-01-14 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.303 Å) 主引用文献 Structural basis for the formation of acylalkylpyrones from two beta-ketoacyl units by the fungal type III polyketide synthase CsyB. J.Biol.Chem., 290, 2015
3WY0	The I375W mutant of CsyB complexed with CoA-SH 分子名称: COENZYME A, Putative uncharacterized protein csyB 著者 Mori, T, Yang, D, Matsui, T, Morita, H, Fujii, I, Abe, I. 登録日 2014-08-13 公開日 2015-01-14 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.001 Å) 主引用文献 Structural basis for the formation of acylalkylpyrones from two beta-ketoacyl units by the fungal type III polyketide synthase CsyB. J.Biol.Chem., 290, 2015
3WXY	Crystal structure of CsyB complexed with CoA-SH 分子名称: COENZYME A, Putative uncharacterized protein csyB 著者 Mori, T, Yang, D, Matsui, T, Morita, H, Fujii, I, Abe, I. 登録日 2014-08-13 公開日 2015-01-14 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.706 Å) 主引用文献 Structural basis for the formation of acylalkylpyrones from two beta-ketoacyl units by the fungal type III polyketide synthase CsyB. J.Biol.Chem., 290, 2015
6B2T	Crystal structure of Xanthomonas campestris OleA H285D 分子名称: 3-oxoacyl-[ACP] synthase III, GLYCEROL, PHOSPHATE ION 著者 Jensen, M.R, Goblirsch, B.R, Esler, M.A, Christenson, J.K, Mohamed, F.A, Wackett, L.P, Wilmot, C.M. 登録日 2017-09-20 公開日 2018-02-28 最終更新日 2020-01-01 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 The role of OleA His285 in orchestration of long-chain acyl-coenzyme A substrates. FEBS Lett., 592, 2018
7WUA	Crystal structures of FadD32 from Corynebacterium diphtheriae 分子名称: Acyl-CoA synthase, MAGNESIUM ION, MYRISTIC ACID, ... 著者 Liu, X. 登録日 2022-02-07 公開日 2022-08-10 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.999 Å) 主引用文献 Crystal structures of FadD32 and pks13-ACP domain from Corynebacterium diphtheriae Biochem Biophys Res Commun, 590, 2022
6ZTC	CRYSTAL STRUCTURE OF PROSTAGLANDIN D2 SYNTHASE IN COMPLEX WITH FRAGMENT 1A AT 1.84A RESOLUTION. 分子名称: 1-[1-(3-fluorophenyl)-6,7-dihydro-4~{H}-pyrazolo[4,3-c]pyridin-5-yl]propan-1-one, GLUTATHIONE, GLYCEROL, ... 著者 Somers, D.O. 登録日 2020-07-17 公開日 2021-07-28 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 A knowledge-based, structural-aided discovery of a novel class of 2-phenylimidazo[1,2-a]pyridine-6-carboxamide H-PGDS inhibitors. Bioorg.Med.Chem.Lett., 47, 2021
3LN0	Structure of compound 5c-S bound at the active site of COX-2 分子名称: (2S)-6,8-dichloro-2-(trifluoromethyl)-2H-chromene-3-carboxylic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Kiefer, J.R, Kurumbail, R.G, Stallings, W.C, Pawlitz, J.L. 登録日 2010-02-01 公開日 2010-10-27 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 The novel benzopyran class of selective cyclooxygenase-2 inhibitors. Part 2: The second clinical candidate having a shorter and favorable human half-life. Bioorg.Med.Chem.Lett., 20, 2010
6RCX	Mycobacterial 4'-phosphopantetheinyl transferase PptAb in complex with the ACP domain of PpsC. 分子名称: CACODYLATE ION, COENZYME A, MANGANESE (II) ION, ... 著者 Nguyen, M.C, Mourey, L, Pedelacq, J.D. 登録日 2019-04-12 公開日 2020-04-15 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Conformational flexibility of coenzyme A and its impact on the post-translational modification of acyl carrier proteins by 4'-phosphopantetheinyl transferases. Febs J., 287, 2020
6V3R	Crystal structure of murine cycloxygenase in complex with a harmaline analog, 4,9-dihydro-3H-pyrido[3,4-b]indole 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 9-[(4-chlorophenyl)methyl]-6-methoxy-1-methyl-4,9-dihydro-3H-beta-carboline, ... 著者 Xu, S, Uddin, M.J, Banerjee, S, Marnett, L.J. 登録日 2019-11-26 公開日 2020-02-26 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.66 Å) 主引用文献 Harmaline Analogs as Substrate-Selective Cyclooxygenase-2 Inhibitors. Acs Med.Chem.Lett., 11, 2020
1OR5	SOLUTION STRUCTURE OF THE HOLO-FORM OF THE FRENOLICIN ACYL CARRIER PROTEIN, MINIMIZED MEAN STRUCTURE 分子名称: acyl carrier protein 著者 Li, Q, Khosla, C, Puglisi, J, Liu, C.W. 登録日 2003-03-11 公開日 2003-07-01 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Solution Structure and Backbone Dynamics of the Holo Form of the Frenolicin Acyl Carrier Protein Biochemistry, 42, 2003
4I45	Crystal Structure of Orf6 protein from Photobacterium profundum, Mg2+-bound form 分子名称: MAGNESIUM ION, ORF6 thioesterase 著者 Rodriguez-Guilbe, M.M, Baerga-Ortiz, A, Schreiter, E.R. 登録日 2012-11-27 公開日 2013-02-27 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Structure, Activity, and Substrate Selectivity of the Orf6 Thioesterase from Photobacterium profundum. J.Biol.Chem., 288, 2013

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