8SXX
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![BU of 8sxx by Molmil](/molmil-images/mine/8sxx) | E. coli dodecamer SIR2 | 分子名称: | NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SIR2-like domain-containing protein | 著者 | Shen, Z.F, Lin, Q.P, Fu, T.M. | 登録日 | 2023-05-24 | 公開日 | 2023-12-27 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Assembly-mediated activation of the SIR2-HerA supramolecular complex for anti-phage defense. Mol.Cell, 83, 2023
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8SUB
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![BU of 8sub by Molmil](/molmil-images/mine/8sub) | E. coli SIR2-HerA complex (dodecamer SIR2 pentamer HerA) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Nucleoside triphosphate hydrolase, ... | 著者 | Shen, Z.F, Lin, Q.P, Fu, T.M. | 登録日 | 2023-05-11 | 公開日 | 2023-12-27 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.89 Å) | 主引用文献 | Assembly-mediated activation of the SIR2-HerA supramolecular complex for anti-phage defense. Mol.Cell, 83, 2023
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8SU9
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![BU of 8su9 by Molmil](/molmil-images/mine/8su9) | E. coli SIR2-HerA complex (hexamer HerA bound with dodecamer Sir2) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Nucleoside triphosphate hydrolase, ... | 著者 | Shen, Z.F, Lin, Q.P, Fu, T.M. | 登録日 | 2023-05-11 | 公開日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (2.83 Å) | 主引用文献 | Assembly-mediated activation of the SIR2-HerA supramolecular complex for anti-phage defense. Mol.Cell, 83, 2023
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8SUW
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![BU of 8suw by Molmil](/molmil-images/mine/8suw) | E. coli SIR2-HerA complex (dodecamer SIR2 bound 4 protomers of HerA) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Nucleoside triphosphate hydrolase, ... | 著者 | Shen, Z.F, Lin, Q.P, Fu, T.M. | 登録日 | 2023-05-13 | 公開日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.15 Å) | 主引用文献 | Assembly-mediated activation of the SIR2-HerA supramolecular complex for anti-phage defense. Mol.Cell, 83, 2023
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7JM5
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![BU of 7jm5 by Molmil](/molmil-images/mine/7jm5) | Crystal structure of KDM4B in complex with QC6352 | 分子名称: | 3-[({(1R)-6-[methyl(phenyl)amino]-1,2,3,4-tetrahydronaphthalen-1-yl}methyl)amino]pyridine-4-carboxylic acid, Lysine-specific demethylase 4B, NICKEL (II) ION, ... | 著者 | White, S.W, Yun, M. | 登録日 | 2020-07-31 | 公開日 | 2022-02-02 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Targeting KDM4 for treating PAX3-FOXO1-driven alveolar rhabdomyosarcoma. Sci Transl Med, 14, 2022
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5YMR
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![BU of 5ymr by Molmil](/molmil-images/mine/5ymr) | The Crystal Structure of IseG | 分子名称: | 2-hydroxyethylsulfonic acid, Formate acetyltransferase, GLYCEROL | 著者 | Lin, L, Zhang, J, Xing, M, Hua, G, Guo, C, Hu, Y, Wei, Y, Ang, E, Zhao, H, Zhang, Y, Yuchi, Z. | 登録日 | 2017-10-22 | 公開日 | 2019-03-20 | 最終更新日 | 2024-03-27 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Radical-mediated C-S bond cleavage in C2 sulfonate degradation by anaerobic bacteria. Nat Commun, 10, 2019
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2CII
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![BU of 2cii by Molmil](/molmil-images/mine/2cii) | The crystal structure of H-2Db complexed with a partial peptide epitope suggests an MHC Class I assembly-intermediate | 分子名称: | BETA-2-MICROGLOBULIN, GLYCEROL, H-2 CLASS I HISTOCOMPATIBILITY ANTIGEN D-B ALPHA CHAIN, ... | 著者 | Glithero, A, Tormo, J, Doering, K, Kojima, M, Jones, E.Y, Elliott, T. | 登録日 | 2006-03-21 | 公開日 | 2006-03-29 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | The crystal structure of H-2D(b) complexed with a partial peptide epitope suggests a major histocompatibility complex class I assembly intermediate. J. Biol. Chem., 281, 2006
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7Y58
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1WND
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![BU of 1wnd by Molmil](/molmil-images/mine/1wnd) | Escherichia coli YdcW gene product is a medium-chain aldehyde dehydrogenase as determined by kinetics and crystal structure | 分子名称: | CALCIUM ION, Putative betaine aldehyde dehydrogenase | 著者 | Gruez, A, Roig-Zamboni, V, Tegoni, M, Cambillau, C. | 登録日 | 2004-07-29 | 公開日 | 2004-10-05 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal Structure and Kinetics Identify Escherichia coli YdcW Gene Product as a Medium-chain Aldehyde Dehydrogenase J.Mol.Biol., 343, 2004
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1WNB
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![BU of 1wnb by Molmil](/molmil-images/mine/1wnb) | Escherichia coli YdcW gene product is a medium-chain aldehyde dehydrogenase (complexed with nadh and betaine aldehyde) | 分子名称: | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, BETAINE ALDEHYDE, Putative betaine aldehyde dehydrogenase | 著者 | Gruez, A, Roig-Zamboni, V, Tegoni, M, Cambillau, C. | 登録日 | 2004-07-29 | 公開日 | 2004-10-05 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal Structure and Kinetics Identify Escherichia coli YdcW Gene Product as a Medium-chain Aldehyde Dehydrogenase J.Mol.Biol., 343, 2004
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4WW3
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6NSO
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![BU of 6nso by Molmil](/molmil-images/mine/6nso) | An Unexpected Intermediate in the Reaction Catalyzed by Quinolinate Synthase | 分子名称: | 1,3-DIHYDROXYACETONEPHOSPHATE, IRON/SULFUR CLUSTER, Quinolinate synthase A | 著者 | Esakova, O.A, Grove, T.L, Silakov, A, Yennawar, N.H, Booker, S.J. | 登録日 | 2019-01-25 | 公開日 | 2019-10-16 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | An Unexpected Species Determined by X-ray Crystallography that May Represent an Intermediate in the Reaction Catalyzed by Quinolinate Synthase. J.Am.Chem.Soc., 141, 2019
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5TCA
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![BU of 5tca by Molmil](/molmil-images/mine/5tca) | Complement Factor D inhibited with JH3 | 分子名称: | 1-(2-{(2S)-2-[(6-bromopyridin-2-yl)carbamoyl]-1,3-thiazolidin-3-yl}-2-oxoethyl)-1H-pyrazolo[3,4-b]pyridine-3-carboxamide, Complement factor D | 著者 | Stuckey, J.A. | 登録日 | 2016-09-14 | 公開日 | 2016-10-19 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | Buried Hydrogen Bond Interactions Contribute to the High Potency of Complement Factor D Inhibitors. ACS Med Chem Lett, 7, 2016
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6S15
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![BU of 6s15 by Molmil](/molmil-images/mine/6s15) | Pyridine derivative of the natural alkaloid Berberine as Human Telomeric G-quadruplex Binder | 分子名称: | Berberine, DNA TAGGGTTAGGGT, POTASSIUM ION | 著者 | Ferraroni, M, Bazzicalupi, C, Gratteri, P, Papi, F. | 登録日 | 2019-06-18 | 公開日 | 2020-06-03 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Pyridine Derivative of the Natural Alkaloid Berberine as Human Telomeric G4-DNA Binder: A Solution and Solid-State Study. Acs Med.Chem.Lett., 11, 2020
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6RJR
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![BU of 6rjr by Molmil](/molmil-images/mine/6rjr) | Crystal structure of a Fungal Catalase at 1.9 Angstrom | 分子名称: | CHLORIDE ION, Catalase, GLYCEROL, ... | 著者 | Gomez, S, Navas-Yuste, S, Payne, A.M, Rivera, W, Lopez-Estepa, M, Brangbour, C, Fulla, D, Juanhuix, J, Fernandez, F.J, Vega, M.C. | 登録日 | 2019-04-29 | 公開日 | 2020-03-11 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.895 Å) | 主引用文献 | Peroxisomal catalases from the yeasts Pichia pastoris and Kluyveromyces lactis as models for oxidative damage in higher eukaryotes. Free Radic. Biol. Med., 141, 2019
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6RJN
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![BU of 6rjn by Molmil](/molmil-images/mine/6rjn) | Crystal structure of a Fungal Catalase at 2.3 Angstroms | 分子名称: | CHLORIDE ION, Catalase, DI(HYDROXYETHYL)ETHER, ... | 著者 | Gomez, S, Navas-Yuste, S, Payne, A.M, Rivera, W, Lopez-Estepa, M, Brangbour, C, Fulla, D, Juanhuix, J, Fernandez, F.J, Vega, M.C. | 登録日 | 2019-04-28 | 公開日 | 2020-03-04 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.295 Å) | 主引用文献 | Peroxisomal catalases from the yeasts Pichia pastoris and Kluyveromyces lactis as models for oxidative damage in higher eukaryotes. Free Radic. Biol. Med., 141, 2019
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8QBC
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![BU of 8qbc by Molmil](/molmil-images/mine/8qbc) | Reactive amide intermediate in sperm whale myoglobin mutant H64V V68A | 分子名称: | ACETATE ION, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE, ... | 著者 | Tinzl, M, Mittl, P.R.E, Hilvert, D. | 登録日 | 2023-08-24 | 公開日 | 2023-12-13 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.23 Å) | 主引用文献 | Myoglobin-Catalyzed Azide Reduction Proceeds via an Anionic Metal Amide Intermediate. J.Am.Chem.Soc., 146, 2024
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5UD9
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![BU of 5ud9 by Molmil](/molmil-images/mine/5ud9) | Crystal structure of 354BG18 Fab | 分子名称: | Fab heavy chain, Light chain | 著者 | Scharf, L, Bjorkman, P.J. | 登録日 | 2016-12-23 | 公開日 | 2017-02-01 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Coexistence of potent HIV-1 broadly neutralizing antibodies and antibody-sensitive viruses in a viremic controller. Sci Transl Med, 9, 2017
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5TCC
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![BU of 5tcc by Molmil](/molmil-images/mine/5tcc) | Complement Factor D inhibited with JH4 | 分子名称: | (2S)-N-(6-bromopyridin-2-yl)-3-[(1H-indazol-1-yl)acetyl]-1,3-thiazolidine-2-carboxamide, Complement factor D | 著者 | Stuckey, J.A. | 登録日 | 2016-09-14 | 公開日 | 2016-10-19 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (3.37 Å) | 主引用文献 | Buried Hydrogen Bond Interactions Contribute to the High Potency of Complement Factor D Inhibitors. ACS Med Chem Lett, 7, 2016
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8PND
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![BU of 8pnd by Molmil](/molmil-images/mine/8pnd) | The ES3 intermediate of hydroxymethylbilane synthase R167Q variant | 分子名称: | 1,2-ETHANEDIOL, 3-[4-(2-hydroxy-2-oxoethyl)-5-[[4-(2-hydroxy-2-oxoethyl)-5-[[4-(2-hydroxy-2-oxoethyl)-5-[[4-(2-hydroxy-2-oxoethyl)-5-[[4-(2-hydroxy-2-oxoethyl)-3-(3-hydroxy-3-oxopropyl)-5-methyl-1~{H}-pyrrol-2-yl]methyl]-3-(3-hydroxy-3-oxopropyl)-1~{H}-pyrrol-2-yl]methyl]-3-(3-hydroxy-3-oxopropyl)-1~{H}-pyrrol-2-yl]methyl]-3-(3-hydroxy-3-oxopropyl)-1~{H}-pyrrol-2-yl]methyl]-1~{H}-pyrrol-3-yl]propanoic acid, GLYCEROL, ... | 著者 | Saeter, M.C, Bustad, H.J, Laitaoja, M, Janis, J, Martinez, A, Aarsand, A.K, Kallio, J.P. | 登録日 | 2023-06-30 | 公開日 | 2023-11-01 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | One ring closer to a closure: the crystal structure of the ES 3 hydroxymethylbilane synthase intermediate. Febs J., 291, 2024
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4Q6I
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![BU of 4q6i by Molmil](/molmil-images/mine/4q6i) | Crystal structure of murine 2D5 Fab, a potent anti-CD4 HIV-1-neutralizing antibody in complex with CD4 | 分子名称: | Heavy chain of murine 2D5 Fab, Light chain of murine 2D5 Fab, T-cell surface glycoprotein CD4 | 著者 | Boyington, J.C, Nabel, G.J, Mascola, J.R. | 登録日 | 2014-04-22 | 公開日 | 2014-07-23 | 実験手法 | X-RAY DIFFRACTION (3.65 Å) | 主引用文献 | Neutralizing antibodies to HIV-1 envelope protect more effectively in vivo than those to the CD4 receptor. Sci Transl Med, 6, 2014
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5VT2
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![BU of 5vt2 by Molmil](/molmil-images/mine/5vt2) | |
4AXK
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![BU of 4axk by Molmil](/molmil-images/mine/4axk) | CRYSTAL STRUCTURE OF subHisA from the thermophile Corynebacterium efficiens | 分子名称: | 1-(5-PHOSPHORIBOSYL)-5-((5'-PHOSPHORIBOSYLAMINO) METHYLIDENEAMINO)IMIDAZOLE-4-CARBOXAMIDE ISOMERASE, GLYCEROL | 著者 | Noda-Garcia, L, Camacho-Zarco, A.R, Medina-Ruiz, S, Verduzco-Castro, E.A, Gaytan, P, Carrillo-Tripp, M, Fulop, V, Barona-Gomez, F. | 登録日 | 2012-06-13 | 公開日 | 2013-06-26 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Evolution of Substrate Specificity in a Recipient'S Enzyme Following Horizontal Gene Transfer. Mol.Biol.Evol., 30, 2013
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7YNH
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![BU of 7ynh by Molmil](/molmil-images/mine/7ynh) | |
7JX1
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![BU of 7jx1 by Molmil](/molmil-images/mine/7jx1) | E. coli TSase complex with a bi-substrate reaction intermediate analog | 分子名称: | (2S)-2-({4-[({(6R)-2,4-diamino-5-[(1-{(2R,4S,5R)-4-hydroxy-5-[(phosphonooxy)methyl]tetrahydrofuran-2-yl}-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)methyl]-5,6,7,8-tetrahydropyrido[3,2-d]pyrimidin-6-yl}methyl)amino]benzoyl}amino)pentanedioic acid (non-preferred name), N-(4-{[(2,4-diamino-7,8-dihydropyrido[3,2-d]pyrimidin-6-yl)methyl]amino}benzene-1-carbonyl)-L-glutamic acid, PHOSPHATE ION, ... | 著者 | Finer-Moore, J, Kholodar, S.A, Stroud, R.M, Kohen, A. | 登録日 | 2020-08-26 | 公開日 | 2021-04-21 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Caught in Action: X-ray Structure of Thymidylate Synthase with Noncovalent Intermediate Analog. Biochemistry, 60, 2021
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