PDB: 13252 件ウェブページステータス検索Chemie searchBIRD

---

6YOV	OCT4-SOX2-bound nucleosome - SHL+6 分子名称: DNA (142-MER), Green fluorescent protein,POU domain, class 5, ... 著者 Michael, A.K, Kempf, G, Cavadini, S, Bunker, R.D, Thoma, N.H. 登録日 2020-04-15 公開日 2020-05-06 最終更新日 2020-07-08 実験手法 ELECTRON MICROSCOPY (3.42 Å) 主引用文献 Mechanisms of OCT4-SOX2 motif readout on nucleosomes. Science, 368, 2020
9EMA	RUVBL1/2 in complex with ATP and CB-6644 inhibitor 分子名称: 5-chloranyl-2-ethoxy-4-fluoranyl-~{N}-[4-[[3-(methoxymethyl)-1-oxidanylidene-6,7-dihydro-5~{H}-pyrazolo[1,2-a][1,2]benzodiazepin-2-yl]amino]-2,2-dimethyl-4-oxidanylidene-butyl]benzamide, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Lopez-Perrote, A, Llorca, O, Garcia-Martin, C. 登録日 2024-03-07 公開日 2024-05-15 実験手法 ELECTRON MICROSCOPY (2.4 Å) 主引用文献 Mechanism of allosteric inhibition of RUVBL1-RUVBL2 by the small-molecule CB-6644 Cell Rep Phys Sci, 2024
9AZP	INF2 at the Barbed End of F-Actin with Incoming Profilin-Actin 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ... 著者 Palmer, N.J, Barrie, K.R, Dominguez, R. 登録日 2024-03-11 公開日 2024-05-29 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.79 Å) 主引用文献 Mechanisms of actin filament severing and elongation by formins. Nature, 2024
6LTJ	Structure of nucleosome-bound human BAF complex 分子名称: AT-rich interactive domain-containing protein 1A, Actin, cytoplasmic 1, ... 著者 He, S, Wu, Z, Tian, Y, Yu, Z, Yu, J, Wang, X, Li, J, Liu, B, Xu, Y. 登録日 2020-01-22 公開日 2020-02-12 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structure of nucleosome-bound human BAF complex. Science, 367, 2020
5KIT	Crystal Structure of Nicotinamide Phosphoribosyltransferase (Nampt) in Complex with Inhibitors 37 分子名称: 1,2-ETHANEDIOL, Nicotinamide phosphoribosyltransferase, PHOSPHATE ION, ... 著者 Li, D, Wang, W. 登録日 2016-06-17 公開日 2016-08-31 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Minimizing CYP2C9 Inhibition of Exposed-Pyridine NAMPT (Nicotinamide Phosphoribosyltransferase) Inhibitors. J.Med.Chem., 59, 2016
5KPM	Glycogen Synthase Kinase 3 beta Complexed with BRD3731 分子名称: (4~{S})-3-(2,2-dimethylpropyl)-4,7,7-trimethyl-4-phenyl-2,6,8,9-tetrahydropyrazolo[3,4-b]quinolin-5-one, Glycogen synthase kinase-3 beta 著者 Lakshminarasimhan, D, White, A, Nadupalli, A, Suto, R.K. 登録日 2016-07-04 公開日 2018-03-14 最終更新日 2018-03-21 実験手法 X-RAY DIFFRACTION (2.69 Å) 主引用文献 Exploiting an Asp-Glu "switch" in glycogen synthase kinase 3 to design paralog-selective inhibitors for use in acute myeloid leukemia. Sci Transl Med, 10, 2018
5KPL	Glycogen Synthase Kinase 3 beta Complexed with BRD0705 分子名称: (4~{S})-4-ethyl-7,7-dimethyl-4-phenyl-2,6,8,9-tetrahydropyrazolo[3,4-b]quinolin-5-one, Glycogen synthase kinase-3 beta 著者 Lakshminarasimhan, D, White, A, Nadupalli, A, Suto, R.K. 登録日 2016-07-04 公開日 2018-03-14 最終更新日 2018-03-21 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Exploiting an Asp-Glu "switch" in glycogen synthase kinase 3 to design paralog-selective inhibitors for use in acute myeloid leukemia. Sci Transl Med, 10, 2018
5N7F	MAGI-1 complexed with a pRSK1 peptide 分子名称: CALCIUM ION, GLYCEROL, Membrane-associated guanylate kinase, ... 著者 Gogl, G, Nyitray, L. 登録日 2017-02-20 公開日 2017-11-08 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Dynamic control of RSK complexes by phosphoswitch-based regulation. FEBS J., 285, 2018
6WKR	PRC2-AEBP2-JARID2 bound to H2AK119ub1 nucleosome 分子名称: DNA (314-MER), Histone H2A type 1, Histone H2B 1.1, ... 著者 Kasinath, V, Nogales, E, Beck, C, Sauer, P, Poepsel, S, Kosmatka, J, Faini, M, Toso, D, Aebersold, R. 登録日 2020-04-16 公開日 2021-02-03 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 JARID2 and AEBP2 regulate PRC2 in the presence of H2AK119ub1 and other histone modifications. Science, 371, 2021
5N7D	MAGI-1 complexed with a RSK1 peptide 分子名称: CALCIUM ION, GLYCEROL, Membrane-associated guanylate kinase, ... 著者 Gogl, G, Nyitray, L. 登録日 2017-02-20 公開日 2017-11-08 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Dynamic control of RSK complexes by phosphoswitch-based regulation. FEBS J., 285, 2018
2I40	Cdk2/Cyclin A complexed with a thiophene carboxamide inhibitor 分子名称: 5-[5,6-BIS(METHYLOXY)-1H-BENZIMIDAZOL-1-YL]-3-{[1-(2-CHLOROPHENYL)ETHYL]OXY}-2-THIOPHENECARBOXAMIDE, Cell division protein kinase 2, Cyclin-A2 著者 Shewchuk, L.M. 登録日 2006-08-21 公開日 2006-10-10 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 5-(1H-Benzimidazol-1-yl)-3-alkoxy-2-thiophenecarbonitriles as potent, selective, inhibitors of IKK-epsilon kinase Bioorg.Med.Chem.Lett., 16, 2006
7B15	14-3-3sigma in complex with SHN3pT869 phosphopeptide crystal structure 分子名称: 14-3-3 protein sigma, MAGNESIUM ION, SHN3pT869 著者 Soini, L, Leysen, S, Davis, J, Ottmann, C. 登録日 2020-11-23 公開日 2021-09-29 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 14-3-3 sigma in complex with phosphopeptides To Be Published
7B13	14-3-3sigma in complex with SHN3pS542 phosphopeptide crystal structure 分子名称: 14-3-3 protein sigma, MAGNESIUM ION, SHN3pS542 著者 Soini, L, Leysen, S, Davis, J, Ottmann, C. 登録日 2020-11-23 公開日 2021-09-29 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.37 Å) 主引用文献 14-3-3 sigma in complex with phosphopeptides To Be Published
6PEO	Cryo-EM structure of alpha-synuclein H50Q Narrow Fibril 分子名称: Alpha-synuclein 著者 Boyer, D.R, Li, B, Sawaya, M.R, Jiang, L, Eisenberg, D.S. 登録日 2019-06-20 公開日 2019-11-27 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structures of fibrils formed by alpha-synuclein hereditary disease mutant H50Q reveal new polymorphs. Nat.Struct.Mol.Biol., 26, 2019
7AW9	CCAAT-binding complex and HapX bound to Aspergillus fumigatus cccA DNA 分子名称: BZIP domain-containing protein, CBFD_NFYB_HMF domain-containing protein, CHLORIDE ION, ... 著者 Huber, E.M, Groll, M. 登録日 2020-11-06 公開日 2022-04-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Structural insights into cooperative DNA recognition by the CCAAT-binding complex and its bZIP transcription factor HapX. Structure, 30, 2022
7AW7	CCAAT-binding complex and HapX bound to Aspergillus nidulans cccA DNA 分子名称: BZIP domain-containing protein, CBFD_NFYB_HMF domain-containing protein, CHLORIDE ION, ... 著者 Huber, E.M, Groll, M. 登録日 2020-11-06 公開日 2022-04-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Structural insights into cooperative DNA recognition by the CCAAT-binding complex and its bZIP transcription factor HapX. Structure, 30, 2022
2J49	Crystal structure of yeast TAF5 N-terminal domain 分子名称: TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 5 著者 Romier, C, James, N, Birck, C, Cavarelli, J, Vivares, C, Collart, M.A, Moras, D. 登録日 2006-08-28 公開日 2007-04-10 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal Structure, Biochemical and Genetic Characterization of Yeast and E. Cuniculi Taf(II)5 N-Terminal Domain: Implications for TFIID Assembly. J.Mol.Biol., 368, 2007
6GEJ	Chromatin remodeller-nucleosome complex at 3.6 A resolution. 分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin-like protein ARP6, BERYLLIUM TRIFLUORIDE ION, ... 著者 Willhoft, O, Chua, E.Y.D, Wilkinson, M, Wigley, D.B. 登録日 2018-04-26 公開日 2018-10-17 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structure and dynamics of the yeast SWR1-nucleosome complex. Science, 362, 2018
6GEN	Chromatin remodeller-nucleosome complex at 4.5 A resolution. 分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin-like protein ARP6, BERYLLIUM TRIFLUORIDE ION, ... 著者 Willhoft, O, Chua, E.Y.D, Wilkinson, M, Wigley, D.B. 登録日 2018-04-27 公開日 2018-10-17 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structure and dynamics of the yeast SWR1-nucleosome complex. Science, 362, 2018
6KW3	The ClassA RSC-Nucleosome Complex 分子名称: Actin-like protein ARP9, Actin-related protein 7, Chromatin structure-remodeling complex protein RSC3, ... 著者 Ye, Y.P, Wu, H, Chen, K.J, Verma, N, Cairns, B, Gao, N, Chen, Z.C. 登録日 2019-09-05 公開日 2019-11-13 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (7.13 Å) 主引用文献 Structure of the RSC complex bound to the nucleosome. Science, 366, 2019
6KW5	The ClassC RSC-Nucleosome Complex 分子名称: Actin-like protein ARP9, Actin-related protein 7, Chromatin structure-remodeling complex protein RSC3, ... 著者 Ye, Y.P, Wu, H, Chen, K.J, Verma, N, Cairns, B, Gao, N, Chen, Z.C. 登録日 2019-09-06 公開日 2020-09-09 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (10.13 Å) 主引用文献 Structure of the RSC complex bound to the nucleosome To Be Published
6KW4	The ClassB RSC-Nucleosome Complex 分子名称: Actin-like protein ARP9, Actin-related protein 7, Chromatin structure-remodeling complex protein RSC3, ... 著者 Ye, Y.P, Wu, H, Chen, K.J, Verma, N, Cairns, B, Gao, N, Chen, Z.C. 登録日 2019-09-06 公開日 2019-11-13 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (7.55 Å) 主引用文献 Structure of the RSC complex bound to the nucleosome. Science, 366, 2019
1JTC	Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag AND LEU 44 REPLACED BY PHE (L44F) 分子名称: FORMIC ACID, acidic fibroblast growth factor 著者 Brych, S.R, Blaber, S.I, Logan, T.M, Blaber, M. 登録日 2001-08-20 公開日 2001-12-19 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core region of a beta-trefoil. Protein Sci., 10, 2001
7SA5	Two-state solution NMR structure of Apo Pin1 分子名称: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 著者 Born, A, Vogeli, B. 登録日 2021-09-22 公開日 2021-10-20 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Reconstruction of Coupled Intra- and Interdomain Protein Motion from Nuclear and Electron Magnetic Resonance. J.Am.Chem.Soc., 143, 2021
4RAF	Crystal structure of PP2Ca-D38A 分子名称: MANGANESE (II) ION, Protein phosphatase 1A 著者 Pan, C, Tang, J.Y, Xu, Y.F, Xiao, P, Liu, H.D, Wang, H.A, Wang, W.B, Meng, F.G, Yu, X, Sun, J.P. 登録日 2014-09-10 公開日 2015-08-26 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.001 Å) 主引用文献 The catalytic role of the M2 metal ion in PP2C alpha Sci Rep, 5, 2015

<295296297298299300301302303304305306307308309310>