6MTE
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![BU of 6mte by Molmil](/molmil-images/mine/6mte) | Rabbit 80S ribosome with eEF2 and SERBP1 (rotated state) | 分子名称: | 18S rRNA, 28S rRNA, 5.8S rRNA, ... | 著者 | Brown, A, Baird, M.R, Yip, M.C.J, Murray, J, Shao, S. | 登録日 | 2018-10-19 | 公開日 | 2018-11-21 | 最終更新日 | 2019-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structures of translationally inactive mammalian ribosomes. Elife, 7, 2018
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6MTC
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![BU of 6mtc by Molmil](/molmil-images/mine/6mtc) | Rabbit 80S ribosome with Z-site tRNA and IFRD2 (unrotated state) | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | 著者 | Brown, A, Baird, M.R, Yip, M.C.J, Murray, J, Shao, S. | 登録日 | 2018-10-19 | 公開日 | 2018-11-21 | 最終更新日 | 2019-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structures of translationally inactive mammalian ribosomes. Elife, 7, 2018
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6MSG
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![BU of 6msg by Molmil](/molmil-images/mine/6msg) | |
6MSB
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![BU of 6msb by Molmil](/molmil-images/mine/6msb) | |
6MSD
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![BU of 6msd by Molmil](/molmil-images/mine/6msd) | |
6MSE
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![BU of 6mse by Molmil](/molmil-images/mine/6mse) | |
6HUE
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![BU of 6hue by Molmil](/molmil-images/mine/6hue) | ParkinS65N | 分子名称: | CHLORIDE ION, E3 ubiquitin-protein ligase parkin, GLYCEROL, ... | 著者 | McWilliams, T.G, Barini, E, Pohjolan-Pirhonen, R, Brooks, S.P, Singh, F, Burel, S, Balk, K, Kumar, A, Montava-Garriga, L, Prescott, A.R, Hassoun, S.M, Mouton-Liger, F, Ball, G, Hills, R, Knebel, A, Ulusoy, A, Di Monte, D.A, Tamjar, J, Antico, O, Fears, K, Smith, L, Brambilla, R, Palin, E, Valori, M, Eerola-Rautio, J, Tienari, P, Corti, O, Dunnett, S.B, Ganley, I.G, Suomalainen, A, Muqit, M.M.K. | 登録日 | 2018-10-07 | 公開日 | 2018-10-17 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Phosphorylation of Parkin at serine 65 is essential for its activation in vivo . Open Biology, 8, 2018
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6HR2
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![BU of 6hr2 by Molmil](/molmil-images/mine/6hr2) | Crystal structure of PROTAC 2 in complex with the bromodomain of human SMARCA4 and pVHL:ElonginC:ElonginB | 分子名称: | (2~{S},4~{R})-~{N}-[[2-[2-[4-[[4-[3-azanyl-6-(2-hydroxyphenyl)pyridazin-4-yl]piperazin-1-yl]methyl]phenyl]ethoxy]-4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]-1-[(2~{S})-2-[(1-fluoranylcyclopropyl)carbonylamino]-3,3-dimethyl-butanoyl]-4-oxidanyl-pyrrolidine-2-carboxamide, 1,2-ETHANEDIOL, DIMETHYL SULFOXIDE, ... | 著者 | Roy, M, Bader, G, Diers, E, Trainor, N, Farnaby, W, Ciulli, A. | 登録日 | 2018-09-26 | 公開日 | 2019-06-12 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | 主引用文献 | BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design. Nat.Chem.Biol., 15, 2019
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6ML1
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![BU of 6ml1 by Molmil](/molmil-images/mine/6ml1) | Structure of the USP15 deubiquitinase domain in complex with an affinity-matured inhibitory Ubv | 分子名称: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | 著者 | Singer, A.U, Teyra, J, Boehmelt, G, Lenter, M, Sicheri, F, Sidhu, S.S. | 登録日 | 2018-09-26 | 公開日 | 2019-01-23 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural and Functional Characterization of Ubiquitin Variant Inhibitors of USP15. Structure, 27, 2019
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6HPR
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6IF1
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![BU of 6if1 by Molmil](/molmil-images/mine/6if1) | Crystal structure of Ube2K and K48-linked di-ubiquitin complex | 分子名称: | Ubiquitin, Ubiquitin-conjugating enzyme E2 K | 著者 | Lee, J.-G, Youn, H.-S, Lee, Y, An, J.Y, Park, K.R, Kang, J.Y, Lim, J.J, Eom, S.H. | 登録日 | 2018-09-18 | 公開日 | 2018-11-21 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.466 Å) | 主引用文献 | Crystal structure of the Ube2K/E2-25K and K48-linked di-ubiquitin complex provides structural insight into the mechanism of K48-specific ubiquitin chain synthesis. Biochem. Biophys. Res. Commun., 506, 2018
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6MDH
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![BU of 6mdh by Molmil](/molmil-images/mine/6mdh) | X-ray crystal structure of ISG15 from Myotis davidii | 分子名称: | Ubiquitin-like protein ISG15 | 著者 | Goodwin, O.Y, Langley, C.A, Dzimianski, J.V, Daczkowski, C.M, Pegan, S.D. | 登録日 | 2018-09-04 | 公開日 | 2018-12-12 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | 主引用文献 | Structure of interferon-stimulated gene product 15 (ISG15) from the bat species Myotis davidii and the impact of interdomain ISG15 interactions on viral protein engagement. Acta Crystallogr D Struct Biol, 75, 2019
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6HIY
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![BU of 6hiy by Molmil](/molmil-images/mine/6hiy) | Cryo-EM structure of the Trypanosoma brucei mitochondrial ribosome - This entry contains the body of the small mitoribosomal subunit in complex with mt-IF-3 | 分子名称: | 9S rRNA, MAGNESIUM ION, SPERMIDINE, ... | 著者 | Ramrath, D.J.F, Niemann, M, Leibundgut, M, Bieri, P, Prange, C, Horn, E.K, Leitner, A, Boehringer, D, Schneider, A, Ban, N. | 登録日 | 2018-08-31 | 公開日 | 2018-09-26 | 最終更新日 | 2019-12-11 | 実験手法 | ELECTRON MICROSCOPY (3.27 Å) | 主引用文献 | Evolutionary shift toward protein-based architecture in trypanosomal mitochondrial ribosomes. Science, 362, 2018
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6HIW
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![BU of 6hiw by Molmil](/molmil-images/mine/6hiw) | Cryo-EM structure of the Trypanosoma brucei mitochondrial ribosome - This entry contains the complete small mitoribosomal subunit in complex with mt-IF-3 | 分子名称: | 9S rRNA, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... | 著者 | Ramrath, D, Niemann, M, Leibundgut, M, Bieri, P, Prange, C, Horn, E.K, Leitner, A, Boehringer, D, Schneider, A, Ban, N. | 登録日 | 2018-08-31 | 公開日 | 2018-09-26 | 最終更新日 | 2019-12-18 | 実験手法 | ELECTRON MICROSCOPY (3.37 Å) | 主引用文献 | Evolutionary shift toward protein-based architecture in trypanosomal mitochondrial ribosomes. Science, 362, 2018
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6HIV
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![BU of 6hiv by Molmil](/molmil-images/mine/6hiv) | Cryo-EM structure of the Trypanosoma brucei mitochondrial ribosome - This entry contains the complete mitoribosome | 分子名称: | 12S rRNA, 50S ribosomal protein L13, putative, ... | 著者 | Ramrath, D.J.F, Niemann, M, Leibundgut, M, Bieri, P, Prange, C, Horn, E.K, Leitner, A, Boerhringer, D, Schneider, A, Ban, N. | 登録日 | 2018-08-31 | 公開日 | 2018-10-03 | 最終更新日 | 2018-11-07 | 実験手法 | ELECTRON MICROSCOPY (7.8 Å) | 主引用文献 | Evolutionary shift toward protein-based architecture in trypanosomal mitochondrial ribosomes. Science, 362, 2018
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6HHQ
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![BU of 6hhq by Molmil](/molmil-images/mine/6hhq) | Crystal structure of compound C45 bound to the yeast 80S ribosome | 分子名称: | (3~{R})-3-[(1~{S})-2-[(1~{S},4~{a}~{R},6~{S},7~{S},8~{a}~{R})-6,7-bis(chloranyl)-5,5,8~{a}-trimethyl-2-methylidene-3,4,4~{a},6,7,8-hexahydro-1~{H}-naphthalen-1-yl]-1-oxidanyl-ethyl]pyrrolidine-2,5-dione, 18S ribosomal RNA, 25S ribosomal RNA, ... | 著者 | Pellegrino, S, Vanderwal, C.D, Yusupov, M. | 登録日 | 2018-08-28 | 公開日 | 2019-02-20 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (3.10000038 Å) | 主引用文献 | Understanding the role of intermolecular interactions between lissoclimides and the eukaryotic ribosome. Nucleic Acids Res., 47, 2019
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6HEI
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6HEK
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6AHD
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![BU of 6ahd by Molmil](/molmil-images/mine/6ahd) | The Cryo-EM Structure of Human Pre-catalytic Spliceosome (B complex) at 3.8 angstrom resolution | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, Brr2, U5 small nuclear ribonucleoprotein 200 kDa helicase, ... | 著者 | Zhan, X, Yan, C, Zhang, X, Shi, Y. | 登録日 | 2018-08-17 | 公開日 | 2018-11-14 | 最終更新日 | 2021-06-30 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structures of the human pre-catalytic spliceosome and its precursor spliceosome. Cell Res., 28, 2018
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6HD7
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![BU of 6hd7 by Molmil](/molmil-images/mine/6hd7) | Cryo-EM structure of the ribosome-NatA complex | 分子名称: | 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, 5.8S rRNA, 5S rRNA, ... | 著者 | Knorr, A.G, Becker, T, Beckmann, R. | 登録日 | 2018-08-17 | 公開日 | 2018-12-19 | 最終更新日 | 2019-01-16 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Ribosome-NatA architecture reveals that rRNA expansion segments coordinate N-terminal acetylation. Nat. Struct. Mol. Biol., 26, 2019
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6HCQ
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![BU of 6hcq by Molmil](/molmil-images/mine/6hcq) | Structure of the rabbit collided di-ribosome (collided monosome) | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | 著者 | Juszkiewicz, S, Chandrasekaran, V, Lin, Z, Kraatz, S, Ramakrishnan, V, Hegde, R.S. | 登録日 | 2018-08-16 | 公開日 | 2018-10-17 | 最終更新日 | 2018-11-14 | 実験手法 | ELECTRON MICROSCOPY (6.5 Å) | 主引用文献 | ZNF598 Is a Quality Control Sensor of Collided Ribosomes. Mol. Cell, 72, 2018
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6AH0
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![BU of 6ah0 by Molmil](/molmil-images/mine/6ah0) | The Cryo-EM Structure of the Precusor of Human Pre-catalytic Spliceosome (pre-B complex) | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | 著者 | Zhan, X, Yan, C, Zhang, X, Shi, Y. | 登録日 | 2018-08-15 | 公開日 | 2018-11-14 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (5.7 Å) | 主引用文献 | Structures of the human pre-catalytic spliceosome and its precursor spliceosome. Cell Res., 28, 2018
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6EF3
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![BU of 6ef3 by Molmil](/molmil-images/mine/6ef3) | Yeast 26S proteasome bound to ubiquitinated substrate (4D motor state) | 分子名称: | 26S proteasome regulatory subunit 4 homolog, 26S proteasome regulatory subunit 6A, 26S proteasome regulatory subunit 6B homolog, ... | 著者 | de la Pena, A.H, Goodall, E.A, Gates, S.N, Lander, G.C, Martin, A. | 登録日 | 2018-08-15 | 公開日 | 2018-10-17 | 最終更新日 | 2020-01-08 | 実験手法 | ELECTRON MICROSCOPY (4.17 Å) | 主引用文献 | Substrate-engaged 26Sproteasome structures reveal mechanisms for ATP-hydrolysis-driven translocation. Science, 362, 2018
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6HCJ
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![BU of 6hcj by Molmil](/molmil-images/mine/6hcj) | Structure of the rabbit 80S ribosome on globin mRNA in the rotated state with A/P and P/E tRNAs | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | 著者 | Juszkiewicz, S, Chandrasekaran, V, Lin, Z, Kraatz, S, Ramakrishnan, V, Hegde, R.S. | 登録日 | 2018-08-15 | 公開日 | 2018-10-17 | 最終更新日 | 2018-11-14 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | ZNF598 Is a Quality Control Sensor of Collided Ribosomes. Mol. Cell, 72, 2018
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6HCM
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![BU of 6hcm by Molmil](/molmil-images/mine/6hcm) | Structure of the rabbit collided di-ribosome (stalled monosome) | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | 著者 | Juszkiewicz, S, Chandrasekaran, V, Lin, Z, Kraatz, S, Ramakrishnan, V, Hegde, R.S. | 登録日 | 2018-08-15 | 公開日 | 2018-10-17 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (6.8 Å) | 主引用文献 | ZNF598 Is a Quality Control Sensor of Collided Ribosomes. Mol. Cell, 72, 2018
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