Structure of the catalytic domain of USP28 (insertion deleted) bound to Ubiquitin-PA

Summary for 6HEI

DescriptorUbiquitin carboxyl-terminal hydrolase 28,Ubiquitin carboxyl-terminal hydrolase 28, Polyubiquitin-B, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywordsubiquitin, usp, ubiquitin-specific protease, dub, deubiquitinase, protease, isopeptidase, usp28, hydrolase
Biological sourceHomo sapiens (Human)
Total number of polymer chains2
Total molecular weight53361.78
Gersch, M.,Komander, D. (deposition date: 2018-08-20, release date: 2019-03-27, Last modification date: 2019-05-15)
Primary citation
Gersch, M.,Wagstaff, J.L.,Toms, A.V.,Graves, B.,Freund, S.M.V.,Komander, D.
Distinct USP25 and USP28 Oligomerization States Regulate Deubiquitinating Activity.
Mol.Cell, 74:436-, 2019
PubMed: 30926242 (PDB entries with the same primary citation)
DOI: 10.1016/j.molcel.2019.02.030
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.21430 1.1% 3.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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