PDB: 1328 件ウェブページステータス検索Chemie searchBIRD

---

5WPL	KRas G12V, bound to GppNHp and miniprotein 225-11 分子名称: CALCIUM ION, GTPase HRas, MAGNESIUM ION, ... 著者 Lee, S.-J, Shim, S.Y, McGee, J.H, Verdine, G.L. 登録日 2017-08-05 公開日 2018-01-03 最終更新日 2018-03-14 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Exceptionally high-affinity Ras binders that remodel its effector domain. J. Biol. Chem., 293, 2018
5WPM	KRas G12V, bound to GppNHp and miniprotein 225-11(A30R) 分子名称: GTPase KRas, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, ... 著者 Lee, S.-J, Shim, S.Y, McGee, J.H, Verdine, G.L. 登録日 2017-08-05 公開日 2018-01-03 最終更新日 2018-03-14 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Exceptionally high-affinity Ras binders that remodel its effector domain. J. Biol. Chem., 293, 2018
5X9S	Crystal structure of fully modified H-Ras-GppNHp 分子名称: CALCIUM ION, GTPase HRas, MAGNESIUM ION, ... 著者 Matsumoto, S, Ke, H, Murashima, Y, Taniguchi-Tamura, H, Miyamoto, R, Yoshikawa, Y, Kumasaka, T, Mizohata, E, Edamatsu, H, Kataoka, T. 登録日 2017-03-09 公開日 2017-08-30 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural basis for intramolecular interaction of post-translationally modified H-RasGTP prepared by protein ligation FEBS Lett., 591, 2017
5XC3	Crystal structure of Acanthamoeba polyphaga mimivirus Rab GTPase in complex with GDP 分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Probable Rab-related GTPase 著者 Ku, B, You, J.A, Kim, S.J. 登録日 2017-03-22 公開日 2017-10-25 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.497 Å) 主引用文献 Crystal structures of two forms of the Acanthamoeba polyphaga mimivirus Rab GTPase Arch. Virol., 162, 2017
5XC5	Crystal structure of Acanthamoeba polyphaga mimivirus Rab GTPase in complex with GTP 分子名称: ACETATE ION, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... 著者 Ku, B, You, J.A, Kim, S.J. 登録日 2017-03-22 公開日 2017-10-25 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.398 Å) 主引用文献 Crystal structures of two forms of the Acanthamoeba polyphaga mimivirus Rab GTPase Arch. Virol., 162, 2017
5XCO	Crystal structure of human K-Ras G12D Mutant in complex with GDP and Cyclic Inhibitory Peptide 分子名称: 1,2-ETHANEDIOL, ACE-ARG-ARG-ARG-ARG-CYS-PRO-LEU-TYR-ILE-SER-TYR-ASP-PRO-VAL-CYS-ARG-ARG-ARG-ARG-NH2, GTPase KRas, ... 著者 Sogabe, S, Miwa, M. 登録日 2017-03-23 公開日 2017-05-24 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Crystal Structure of a Human K-Ras G12D Mutant in Complex with GDP and the Cyclic Inhibitory Peptide KRpep-2d ACS Med Chem Lett, 8, 2017
5XR4	Crystal structure of RabA1a in complex with GDP 分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ras-related protein RABA1a, ... 著者 Yun, J.S, Chang, J.H. 登録日 2017-06-07 公開日 2018-06-13 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structure and subcellular localization of RabA1a from Arabidopsis thaliana To Be Published
5XR6	Crystal structure of RabA1a in complex with GppNHp 分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Ras-related protein RABA1a 著者 Yun, J.S, Chang, J.H. 登録日 2017-06-07 公開日 2018-06-13 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structure and subcellular localization of RabA1a from Arabidopsis thaliana To Be Published
5XR7	Crystal structure of RabA1a (Q72K) in complex with GTP 分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Ras-related protein RABA1a 著者 Yun, J.S, Chang, J.H. 登録日 2017-06-07 公開日 2018-06-13 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structure and subcellular localization of RabA1a from Arabidopsis thaliana To Be Published
5YOZ	Solution structure of truncated Rab5a from Leishmania donovani 分子名称: Rab5a 著者 Maheshwari, D, Yadav, R, Mukhopadhyay, A, Arora, A. 登録日 2017-10-31 公開日 2018-10-24 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Structural and Biophysical Characterization of Rab5a from Leishmania Donovani Biophys. J., 115, 2018
5YRO	RanL182A in complex with RanBP1-CRM1 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1,Exportin-1, ... 著者 Sun, Q, Zhang, Y. 登録日 2017-11-09 公開日 2018-11-21 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.396 Å) 主引用文献 RanL182A in complex with RanBP1-CRM1 To Be Published
5YST	RanM189D in complex with RanBP1-CRM1 分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, Exportin-1,Exportin-1, ... 著者 Sun, Q, Zhang, Y. 登録日 2017-11-15 公開日 2018-11-21 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 RanM189D in complex with RanBP1-CRM1 To Be Published
5YSU	Plumbagin in complex with CRM1-RanM189D-RanBP1 分子名称: (2~{R})-2-methyl-5-oxidanyl-2,3-dihydronaphthalene-1,4-dione, CHLORIDE ION, Exportin-1,Exportin-1, ... 著者 Sun, Q, Zhang, Y. 登録日 2017-11-15 公開日 2018-11-21 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 RanL182A in complex with RanBP1-CRM1 To Be Published
5YTB	RanY197A in complex with RanBP1-CRM1 分子名称: 1,2-ETHANEDIOL, ACETATE ION, CHLORIDE ION, ... 著者 Sun, Q, Zhang, Y. 登録日 2017-11-17 公開日 2018-11-21 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 RanY197A in complex with RanBP1-CRM1 To Be Published
5YU6	CRYSTAL STRUCTURE OF EXPORTIN-5:RANGTP COMPLEX 分子名称: 13-mer peptide, Exportin-5, GTP-binding nuclear protein Ran, ... 著者 Yamazawa, R, Jiko, C, Lee, S.J, Yamashita, E. 登録日 2017-11-20 公開日 2018-08-29 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.997 Å) 主引用文献 Structural Basis for Selective Binding of Export Cargoes by Exportin-5 Structure, 26, 2018
5YXH	Structure of Rheb-GDP 分子名称: GTP-binding protein Rheb, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION 著者 Mahoney, S.J. 登録日 2017-12-05 公開日 2018-02-28 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 A small molecule inhibitor of Rheb selectively targets mTORC1 signaling. Nat Commun, 9, 2018
5YXZ	Co-crystal Structure of KRAS (G12C) covalently bound with Quinazoline based inhibitor JBI484 分子名称: 1,2-ETHANEDIOL, 1-[4-[6-chloranyl-8-fluoranyl-7-(2-fluorophenyl)quinazolin-4-yl]piperazin-1-yl]propan-1-one, GTPase KRas, ... 著者 Swaminathan, S, Thakur, M.K, Kandan, S, Gautam, A, Kanavalli, M, Simhadri, P, Gosu, R. 登録日 2017-12-07 公開日 2018-04-18 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Co-crystal Structure of KRAS (G12C) covalently bound with Quinazoline based inhibitor JBI484 To Be Published
5YY1	Co-crystal Structure of KRAS (G12C) covalently bound with Quinazoline based inhibitor JBI739 分子名称: 1,2-ETHANEDIOL, 1-[4-[6-chloranyl-8-fluoranyl-7-[2-(trifluoromethyl)phenyl]quinazolin-4-yl]piperazin-1-yl]propan-1-one, GTPase KRas, ... 著者 Swaminathan, S, Thakur, M.K, Kandan, S, Gautam, A, Kanavalli, M, Simhadri, P, Gosu, R. 登録日 2017-12-07 公開日 2018-04-18 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Co-crystal Structure of KRAS (G12C) covalently bound with Quinazoline based inhibitor JBI739 To Be Published
5Z2M	Structure of Orp1L/Rab7 complex 分子名称: GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Oxysterol-binding protein-related protein 1, ... 著者 Ma, X.L, Liu, K, Li, J, Li, H.H, Li, J, Yang, C.L, Liang, H.H. 登録日 2018-01-03 公開日 2018-08-08 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.142 Å) 主引用文献 A non-canonical GTPase interaction enables ORP1L-Rab7-RILP complex formation and late endosome positioning. J. Biol. Chem., 293, 2018
5ZC6	Solution structure of H-RasT35S mutant protein in complex with KBFM123 分子名称: 3-oxidanyl-~{N}-[[(2~{R})-oxolan-2-yl]methyl]naphthalene-2-carboxamide, GTPase HRas, MAGNESIUM ION, ... 著者 Matsumoto, S, Hayashi, Y, Hiraga, T, Matsuo, K, Kataoka, T. 登録日 2018-02-15 公開日 2018-09-12 最終更新日 2024-05-01 実験手法 SOLUTION NMR 主引用文献 Molecular Basis for Allosteric Inhibition of GTP-Bound H-Ras Protein by a Small-Molecule Compound Carrying a Naphthalene Ring Biochemistry, 57, 2018
5ZHX	Crystal structure of SmgGDS-558 and farnesylated RhoA complex 分子名称: FARNESYL, Rap1 GTPase-GDP dissociation stimulator 1, Transforming protein RhoA 著者 Shimizu, H, Toma-Fukai, S, Shimizu, T. 登録日 2018-03-13 公開日 2018-09-05 最終更新日 2018-10-03 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 GEF mechanism revealed by the structure of SmgGDS-558 and farnesylated RhoA complex and its implication for a chaperone mechanism. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5ZPU	LFS829 in complex with CRM1-Ran-RanBP1 分子名称: (Z)-{[(3E)-4-{(R)-[3,5-bis(trifluoromethyl)phenyl]sulfinyl}but-3-en-1-yl]imino}methanethiol, CHLORIDE ION, Exportin-1,Exportin-1, ... 著者 Sun, Q, Lei, Y. 登録日 2018-04-16 公開日 2019-04-17 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 To be published To Be Published
5ZVP	Aspergillus fumigatus Rho1 F25N 分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Rho GTPase Rho1, ... 著者 Wei, W.F, Van Aalten, D.M.F. 登録日 2018-05-12 公開日 2019-05-15 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Aspergillus fumigateurs Rho1 F25N To Be Published
621P	THREE-DIMENSIONAL STRUCTURES OF H-RAS P21 MUTANTS: MOLECULAR BASIS FOR THEIR INABILITY TO FUNCTION AS SIGNAL SWITCH MOLECULES 分子名称: H-RAS P21 PROTEIN, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER 著者 Krengel, U, Scherer, A, Kabsch, W, Wittinghofer, A, Pai, E.F. 登録日 1991-06-06 公開日 1994-01-31 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Three-dimensional structures of H-ras p21 mutants: molecular basis for their inability to function as signal switch molecules. Cell(Cambridge,Mass.), 62, 1990
6A38	MVM NS2 NES in complex with CRM1-Ran-RanBP1 分子名称: 1,2-ETHANEDIOL, Exportin-1, GLYCEROL, ... 著者 Sun, Q, Li, Y. 登録日 2018-06-15 公開日 2019-06-19 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.69 Å) 主引用文献 Cancer Therapy with Nanoparticle-Medicated Intracellular Expression of Peptide CRM1-Inhibitor. Int J Nanomedicine, 16, 2021

<23242526272829303132333435363738>