3EX7
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5MPG
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5MQF
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![BU of 5mqf by Molmil](/molmil-images/mine/5mqf) | Cryo-EM structure of a human spliceosome activated for step 2 of splicing (C* complex) | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, ATP-dependent RNA helicase DHX8, Cell division cycle 5-like protein, ... | 著者 | Bertram, K, Hartmuth, K, Kastner, B. | 登録日 | 2016-12-20 | 公開日 | 2017-03-22 | 最終更新日 | 2018-11-21 | 実験手法 | ELECTRON MICROSCOPY (5.9 Å) | 主引用文献 | Cryo-EM structure of a human spliceosome activated for step 2 of splicing. Nature, 542, 2017
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2J0S
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![BU of 2j0s by Molmil](/molmil-images/mine/2j0s) | The crystal structure of the Exon Junction Complex at 2.2 A resolution | 分子名称: | 5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP *UP*UP*UP*UP*U)-3', ATP-DEPENDENT RNA HELICASE DDX48, MAGNESIUM ION, ... | 著者 | Bono, F, Ebert, J, Lorentzen, E, Conti, E. | 登録日 | 2006-08-04 | 公開日 | 2006-09-06 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | The Crystal Structure of the Exon Junction Complex Reveals How It Mantains a Stable Grip on Mrna Cell(Cambridge,Mass.), 126, 2006
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2J0Q
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![BU of 2j0q by Molmil](/molmil-images/mine/2j0q) | The crystal structure of the Exon Junction Complex at 3.2 A resolution | 分子名称: | 5'-R(*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*UP*U)-3', ATP-DEPENDENT RNA HELICASE DDX48, MAGNESIUM ION, ... | 著者 | Bono, F, Ebert, J, Lorentzen, E, Conti, E. | 登録日 | 2006-08-04 | 公開日 | 2006-08-30 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | The Crystal Structure of the Exon Junction Complex Reveals How It Maintains a Stable Grip on Mrna. Cell(Cambridge,Mass.), 126, 2006
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6ZHE
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![BU of 6zhe by Molmil](/molmil-images/mine/6zhe) | Cryo-EM structure of DNA-PK dimer | 分子名称: | DNA (25-MER), DNA (26-MER), DNA (27-MER), ... | 著者 | Chaplin, A.K, Hardwick, S.W, Chirgadze, D.Y, Blundell, T.L. | 登録日 | 2020-06-23 | 公開日 | 2020-10-21 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (7.24 Å) | 主引用文献 | Dimers of DNA-PK create a stage for DNA double-strand break repair. Nat.Struct.Mol.Biol., 28, 2021
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7NVL
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![BU of 7nvl by Molmil](/molmil-images/mine/7nvl) | Human TRiC complex in closed state with nanobody bound (Consensus Map) | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ... | 著者 | Kelly, J.J, Chi, G, Bulawa, C, Paavilainen, V.O, Bountra, C, Huiskonen, J.T, Yue, W, Structural Genomics Consortium (SGC) | 登録日 | 2021-03-15 | 公開日 | 2022-03-02 | 最終更新日 | 2022-06-01 | 実験手法 | ELECTRON MICROSCOPY (2.5 Å) | 主引用文献 | Snapshots of actin and tubulin folding inside the TRiC chaperonin. Nat.Struct.Mol.Biol., 29, 2022
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1KPS
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![BU of 1kps by Molmil](/molmil-images/mine/1kps) | Structural Basis for E2-mediated SUMO conjugation revealed by a complex between ubiquitin conjugating enzyme Ubc9 and RanGAP1 | 分子名称: | Ran-GTPase activating protein 1, SULFATE ION, Ubiquitin-like protein SUMO-1 conjugating enzyme | 著者 | Bernier-Villamor, V, Sampson, D.A, Matunis, M.J, Lima, C.D. | 登録日 | 2002-01-02 | 公開日 | 2002-02-13 | 最終更新日 | 2017-10-11 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural basis for E2-mediated SUMO conjugation revealed by a complex between ubiquitin-conjugating enzyme Ubc9 and RanGAP1. Cell(Cambridge,Mass.), 108, 2002
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6T59
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![BU of 6t59 by Molmil](/molmil-images/mine/6t59) | Structure of rabbit 80S ribosome translating beta-tubulin in complex with tetratricopeptide protein 5 and nascent chain-associated complex | 分子名称: | 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | 著者 | Lin, Z, Gasic, I, Chandrasekaran, V, Peters, N, Shao, S, Ramakrishnan, V, Mitchison, T.J, Hegde, R.S. | 登録日 | 2019-10-15 | 公開日 | 2019-11-27 | 最終更新日 | 2020-01-15 | 実験手法 | ELECTRON MICROSCOPY (3.11 Å) | 主引用文献 | TTC5 mediates autoregulation of tubulin via mRNA degradation. Science, 367, 2020
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3KYD
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![BU of 3kyd by Molmil](/molmil-images/mine/3kyd) | Human SUMO E1~SUMO1-AMP tetrahedral intermediate mimic | 分子名称: | 1,2-ETHANEDIOL, 5'-{[(3-aminopropyl)sulfonyl]amino}-5'-deoxyadenosine, SUMO-activating enzyme subunit 1, ... | 著者 | Lima, C.D. | 登録日 | 2009-12-05 | 公開日 | 2010-02-16 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.61 Å) | 主引用文献 | Active site remodelling accompanies thioester bond formation in the SUMO E1. Nature, 463, 2010
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1A5R
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![BU of 1a5r by Molmil](/molmil-images/mine/1a5r) | STRUCTURE DETERMINATION OF THE SMALL UBIQUITIN-RELATED MODIFIER SUMO-1, NMR, 10 STRUCTURES | 分子名称: | SUMO-1 | 著者 | Bayer, P, Arndt, A, Metzger, S, Mahajan, R, Melchior, F, Jaenicke, R, Becker, J. | 登録日 | 1998-02-18 | 公開日 | 1998-10-14 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure determination of the small ubiquitin-related modifier SUMO-1. J.Mol.Biol., 280, 1998
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7TRC
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![BU of 7trc by Molmil](/molmil-images/mine/7trc) | Human telomerase H/ACA RNP at 3.3 Angstrom | 分子名称: | H/ACA ribonucleoprotein complex subunit 1, H/ACA ribonucleoprotein complex subunit 2, H/ACA ribonucleoprotein complex subunit 3, ... | 著者 | Liu, B, He, Y, Wang, Y, Song, H, Zhou, Z.H, Feigon, J. | 登録日 | 2022-01-28 | 公開日 | 2022-04-20 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structure of active human telomerase with telomere shelterin protein TPP1. Nature, 604, 2022
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7TOQ
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![BU of 7toq by Molmil](/molmil-images/mine/7toq) | Mammalian 80S ribosome bound with the ALS/FTD-associated dipeptide repeat protein poly-PR | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | 著者 | Loveland, A.B, Svidritskiy, E, Susorov, D, Lee, S, Park, A, Zvornicanin, S, Demo, G, Gao, F.B, Korostelev, A.A. | 登録日 | 2022-01-24 | 公開日 | 2022-05-25 | 最終更新日 | 2024-02-21 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Ribosome inhibition by C9ORF72-ALS/FTD-associated poly-PR and poly-GR proteins revealed by cryo-EM. Nat Commun, 13, 2022
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6ZY7
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![BU of 6zy7 by Molmil](/molmil-images/mine/6zy7) | Cryo-EM structure of the entire Human topoisomerase II alpha in State 1 | 分子名称: | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside, DNA (5'-D(*CP*GP*CP*GP*CP*AP*TP*CP*GP*TP*CP*AP*TP*CP*CP*TP*C)-3'), DNA (5'-D(*GP*AP*GP*GP*AP*TP*GP*AP*CP*GP*AP*TP*G)-3'), ... | 著者 | Vanden Broeck, A, Lamour, V. | 登録日 | 2020-07-30 | 公開日 | 2021-05-26 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (4.64 Å) | 主引用文献 | Structural basis for allosteric regulation of Human Topoisomerase II alpha. Nat Commun, 12, 2021
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6ZY6
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![BU of 6zy6 by Molmil](/molmil-images/mine/6zy6) | Cryo-EM structure of the Human topoisomerase II alpha DNA-binding/cleavage domain in State 2 | 分子名称: | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside, DNA (5'-D(*CP*GP*CP*GP*CP*AP*TP*CP*GP*TP*CP*AP*TP*CP*CP*TP*C)-3'), DNA (5'-D(*GP*AP*GP*GP*AP*TP*GP*AP*CP*GP*AP*TP*G)-3'), ... | 著者 | Vanden Broeck, A, Lamour, V. | 登録日 | 2020-07-30 | 公開日 | 2021-05-26 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structural basis for allosteric regulation of Human Topoisomerase II alpha. Nat Commun, 12, 2021
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6ZY8
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![BU of 6zy8 by Molmil](/molmil-images/mine/6zy8) | Cryo-EM structure of the entire Human topoisomerase II alpha in State 2 | 分子名称: | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside, DNA (5'-D(*CP*GP*CP*GP*CP*AP*TP*CP*GP*TP*CP*AP*TP*CP*CP*TP*C)-3'), DNA (5'-D(*GP*AP*GP*GP*AP*TP*GP*AP*CP*GP*AP*TP*G)-3'), ... | 著者 | Vanden Broeck, A, Lamour, V. | 登録日 | 2020-07-30 | 公開日 | 2021-05-26 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (7.4 Å) | 主引用文献 | Structural basis for allosteric regulation of Human Topoisomerase II alpha. Nat Commun, 12, 2021
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6ZY5
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![BU of 6zy5 by Molmil](/molmil-images/mine/6zy5) | Cryo-EM structure of the Human topoisomerase II alpha DNA-binding/cleavage domain in State 1 | 分子名称: | (5S,5aR,8aR,9R)-9-(4-hydroxy-3,5-dimethoxyphenyl)-8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol -5-yl 4,6-O-[(1R)-ethylidene]-beta-D-glucopyranoside, DNA (5'-D(*CP*GP*CP*GP*CP*AP*TP*CP*GP*TP*CP*AP*TP*CP*CP*TP*C)-3'), DNA (5'-D(*GP*AP*GP*GP*AP*TP*GP*AP*CP*GP*AP*TP*G)-3'), ... | 著者 | Vanden Broeck, A, Lamour, V. | 登録日 | 2020-07-30 | 公開日 | 2021-05-26 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structural basis for allosteric regulation of Human Topoisomerase II alpha. Nat Commun, 12, 2021
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6P5J
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![BU of 6p5j by Molmil](/molmil-images/mine/6p5j) | Structure of a mammalian 80S ribosome in complex with the Israeli Acute Paralysis Virus IRES (Class 2) | 分子名称: | 18S rRNA, 28S rRNA, 5.8S rRNA, ... | 著者 | Acosta-Reyes, F.J, Neupane, R, Frank, J, Fernandez, I.S. | 登録日 | 2019-05-30 | 公開日 | 2019-09-18 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs. Embo J., 38, 2019
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6P5I
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![BU of 6p5i by Molmil](/molmil-images/mine/6p5i) | Structure of a mammalian 80S ribosome in complex with the Israeli Acute Paralysis Virus IRES (Class 1) | 分子名称: | 18S rRNA, 28S rRNA, 5.8S rRNA, ... | 著者 | Acosta-Reyes, F.J, Neupane, R, Frank, J, Fernandez, I.S. | 登録日 | 2019-05-30 | 公開日 | 2019-09-18 | 最終更新日 | 2020-02-26 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs. Embo J., 38, 2019
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1Y8R
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6RYR
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![BU of 6ryr by Molmil](/molmil-images/mine/6ryr) | Nucleosome-CHD4 complex structure (single CHD4 copy) | 分子名称: | Chromodomain-helicase-DNA-binding protein 4,Chromodomain-helicase-DNA-binding protein 4,Chromodomain-helicase-DNA-binding protein 4, DNA (149-MER), Histone H2A type 1, ... | 著者 | Farnung, L, Ochmann, M, Cramer, P. | 登録日 | 2019-06-11 | 公開日 | 2020-07-15 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Nucleosome-CHD4 chromatin remodeller structure maps human disease mutations. Elife, 9, 2020
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6RYU
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![BU of 6ryu by Molmil](/molmil-images/mine/6ryu) | Nucleosome-CHD4 complex structure (two CHD4 copies) | 分子名称: | Chromodomain-helicase-DNA-binding protein 4,CHD4,Chromodomain-helicase-DNA-binding protein 4, DNA (149-MER), Histone H2A type 1, ... | 著者 | Farnung, L, Ochmann, M, Cramer, P. | 登録日 | 2019-06-12 | 公開日 | 2020-07-15 | 最終更新日 | 2024-05-22 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Nucleosome-CHD4 chromatin remodeller structure maps human disease mutations. Elife, 9, 2020
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3RZW
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1D4U
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![BU of 1d4u by Molmil](/molmil-images/mine/1d4u) | INTERACTIONS OF HUMAN NUCLEOTIDE EXCISION REPAIR PROTEIN XPA WITH RPA70 AND DNA: CHEMICAL SHIFT MAPPING AND 15N NMR RELAXATION STUDIES | 分子名称: | NUCLEOTIDE EXCISION REPAIR PROTEIN XPA (XPA-MBD), ZINC ION | 著者 | Buchko, G.W, Daughdrill, G.W, de Lorimier, R, Rao, S, Isern, N.G, Lingbeck, J, Taylor, J, Wold, M.S, Gochin, M, Spicer, L.D, Lowry, D.F, Kennedy, M.A. | 登録日 | 1999-10-06 | 公開日 | 1999-10-17 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Interactions of human nucleotide excision repair protein XPA with DNA and RPA70 Delta C327: chemical shift mapping and 15N NMR relaxation studies. Biochemistry, 38, 1999
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7AOA
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![BU of 7aoa by Molmil](/molmil-images/mine/7aoa) | Structure of the extended MTA1/HDAC1/MBD2/RBBP4 NURD deacetylase complex | 分子名称: | Histone deacetylase 1, Histone-binding protein RBBP4, INOSITOL HEXAKISPHOSPHATE, ... | 著者 | Millard, C.J, Fairall, L, Ragan, T.J, Savva, C.G, Schwabe, J.W.R. | 登録日 | 2020-10-14 | 公開日 | 2020-11-11 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (19.4 Å) | 主引用文献 | The topology of chromatin-binding domains in the NuRD deacetylase complex. Nucleic Acids Res., 48, 2020
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