PDB: 331 件ウェブページステータス検索Chemie searchBIRD

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6DVE	Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF selenomethionine-labelled sigma factor L) with 6 nt spacer 分子名称: DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*T)-3'), DNA (5'-D(P*CP*GP*TP*GP*TP*GP*AP*GP*TP*AP*AP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ... 著者 Lin, W, Das, K, Feng, Y, Ebright, R.H. 登録日 2018-06-23 公開日 2019-02-20 最終更新日 2019-02-27 実験手法 X-RAY DIFFRACTION (3.812 Å) 主引用文献 Structural basis of ECF-sigma-factor-dependent transcription initiation. Nat Commun, 10, 2019
5IPM	SigmaS-transcription initiation complex with 4-nt nascent RNA 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Liu, B, Zuo, Y, Steitz, T.A. 登録日 2016-03-09 公開日 2016-03-30 最終更新日 2016-06-22 実験手法 X-RAY DIFFRACTION (4.2 Å) 主引用文献 Structures of E. coli sigma S-transcription initiation complexes provide new insights into polymerase mechanism. Proc.Natl.Acad.Sci.USA, 113, 2016
6DV9	Crystal structure of Mycobacterium tuberculosis transcription initiation complex(ECF sigma factor L) containing 5nt RNA with 4nt spacer 分子名称: DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*G)-3'), DNA (5'-D(P*CP*GP*TP*GP*TP*CP*AP*GP*AP*GP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ... 著者 Lin, W, Das, K, Feng, Y, Ebright, R.H. 登録日 2018-06-23 公開日 2019-02-20 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 Structural basis of ECF-sigma-factor-dependent transcription initiation. Nat Commun, 10, 2019
6TYF	Crystal structure of MTB sigma L transcription initiation complex with 6 nt long RNA primer 分子名称: DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*AP*TP*CP*GP*AP*GP*GP*GP*T)-3'), DNA (5'-D(P*GP*TP*GP*TP*CP*AP*GP*TP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ... 著者 Molodtsov, V, Ebright, R.H. 登録日 2019-08-08 公開日 2020-03-11 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription. Proc.Natl.Acad.Sci.USA, 117, 2020
6TYG	Crystal structure of MTB sigma L transcription initiation complex with 9 nt long RNA primer 分子名称: DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*AP*TP*CP*GP*AP*GP*GP*GP*TP*G)-3'), DNA (5'-D(P*GP*TP*GP*TP*CP*AP*GP*TP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ... 著者 Molodtsov, V, Ebright, R.H. 登録日 2019-08-08 公開日 2020-03-11 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription. Proc.Natl.Acad.Sci.USA, 117, 2020
3IYD	Three-dimensional EM structure of an intact activator-dependent transcription initiation complex 分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Catabolite gene activator, DNA (98-MER), ... 著者 Hudson, B.P, Quispe, J, Lara, S, Kim, Y, Berman, H, Arnold, E, Ebright, R.H, Lawson, C.L. 登録日 2009-08-01 公開日 2009-11-10 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (19.799999 Å) 主引用文献 Three-dimensional EM structure of an intact activator-dependent transcription initiation complex Proc.Natl.Acad.Sci.USA, 106, 2009
5IPL	SigmaS-transcription initiation complex with 4-nt nascent RNA 分子名称: DIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Liu, B, Zuo, Y, Steitz, T.A. 登録日 2016-03-09 公開日 2016-03-30 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Structures of E. coli sigma S-transcription initiation complexes provide new insights into polymerase mechanism. Proc.Natl.Acad.Sci.USA, 113, 2016
5I2D	Crystal structure of T. thermophilus TTHB099 class II transcription activation complex: TAP-RPo 分子名称: DNA (72-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Feng, Y, Zhang, Y, Ebright, R.H. 登録日 2016-02-08 公開日 2016-06-22 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (4.405 Å) 主引用文献 Structural basis of transcription activation. Science, 352, 2016
6TYE	Crystal structure of MTB sigma L transcription initiation complex with 5 nt long RNA primer 分子名称: DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*AP*TP*CP*GP*AP*GP*G)-3'), DNA (5'-D(P*GP*TP*GP*TP*CP*AP*GP*TP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ... 著者 Molodtsov, V, Ebright, R.H. 登録日 2019-08-08 公開日 2020-03-11 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.79 Å) 主引用文献 RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription. Proc.Natl.Acad.Sci.USA, 117, 2020
3LEV	HIV-1 antibody 2F5 in complex with epitope scaffold ES2 分子名称: 2F5 ANTIBODY HEAVY CHAIN, 2F5 ANTIBODY LIGHT CHAIN, ADENOSINE-5'-TRIPHOSPHATE, ... 著者 Ofek, G, Guenaga, F.J, Schief, W.R, Skinner, J, Baker, D, Wyatt, R, Kwong, P.D. 登録日 2010-01-15 公開日 2010-09-29 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Elicitation of structure-specific antibodies by epitope scaffolds. Proc.Natl.Acad.Sci.USA, 107, 2010
3LES	2F5 Epitope scaffold ES2 分子名称: RNA polymerase sigma factor, SULFATE ION 著者 Ofek, G, Guenaga, F.J, Schief, W.R, Skinner, J, Wyatt, R, Baker, D, Kwong, P.D. 登録日 2010-01-15 公開日 2010-09-29 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.77 Å) 主引用文献 Elicitation of structure-specific antibodies by epitope scaffolds. Proc.Natl.Acad.Sci.USA, 107, 2010
1SC5	Sigma-28(FliA)/FlgM complex 分子名称: RNA polymerase sigma factor FliA, anti-sigma factor FlgM 著者 Sorenson, M.K, Ray, S.S, Darst, S.A. 登録日 2004-02-11 公開日 2004-04-06 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (3.26 Å) 主引用文献 Crystal structure of the flagellar sigma/anti-sigma complex sigma(28)/FlgM reveals an intact sigma factor in an inactive conformation. Mol.Cell, 14, 2004
1SIG	CRYSTAL STRUCTURE OF A SIGMA70 SUBUNIT FRAGMENT FROM ESCHERICHIA COLI RNA POLYMERASE 分子名称: RNA POLYMERASE PRIMARY SIGMA FACTOR 著者 Malhotra, A, Severinova, E, Darst, S.A. 登録日 1997-02-18 公開日 1997-05-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structure of a sigma 70 subunit fragment from E. coli RNA polymerase. Cell(Cambridge,Mass.), 87, 1996
1RP3	Cocrystal structure of the flagellar sigma/anti-sigma complex, Sigma-28/FlgM 分子名称: RNA polymerase sigma factor SIGMA-28 (FliA), anti sigma factor FlgM 著者 Sorenson, M.K, Ray, S.S, Darst, S.A. 登録日 2003-12-02 公開日 2004-04-06 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal Structure of the Flagellar Sigma/Anti-Sigma Complex Sigma(28)/FlgM Reveals an Intact Sigma Factor in an Inactive Conformation Mol.Cell, 14, 2004
5D4D	Crystal structure of Thermus thermophilus product complex for transcription initiation with NAD and CTP 分子名称: ADENOSINE MONOPHOSPHATE, CYTIDINE-5'-MONOPHOSPHATE, CYTIDINE-5'-TRIPHOSPHATE, ... 著者 Zhang, Y, Ebright, R.H. 登録日 2015-08-07 公開日 2016-07-06 最終更新日 2024-05-29 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 The mechanism of RNA 5' capping with NAD(+), NADH and desphospho-CoA. Nature, 535, 2016
5D4C	Crystal structure of Thermus thermophilus product complex for transcription initiation with ATP and CTP 分子名称: ADENOSINE-5'-TRIPHOSPHATE, CYTIDINE-5'-MONOPHOSPHATE, CYTIDINE-5'-TRIPHOSPHATE, ... 著者 Zhang, Y, Ebright, R.H. 登録日 2015-08-07 公開日 2016-07-06 最終更新日 2024-07-03 実験手法 X-RAY DIFFRACTION (3.28 Å) 主引用文献 The mechanism of RNA 5' capping with NAD(+), NADH and desphospho-CoA. Nature, 535, 2016
5D4E	Crystal structure of Thermus thermophilus product complex for transcription initiation with 3'-dephosphate-CoA and CTP 分子名称: CYTIDINE-5'-MONOPHOSPHATE, DEPHOSPHO COENZYME A, DIPHOSPHATE, ... 著者 Zhang, Y, Ebright, R.H. 登録日 2015-08-07 公開日 2016-07-06 最終更新日 2024-07-03 実験手法 X-RAY DIFFRACTION (3.08 Å) 主引用文献 The mechanism of RNA 5' capping with NAD(+), NADH and desphospho-CoA. Nature, 535, 2016
5E17	T. thermophilus transcription initiation complex having a RRR discriminator sequence and a nontemplate-strand length corresponding to TSS selection at position 7 (RPo-GGG-7) 分子名称: DNA (27-MER), DNA (5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3'), DNA-directed RNA polymerase subunit alpha, ... 著者 Zhang, Y, Ebright, R.H. 登録日 2015-09-29 公開日 2016-03-09 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Multiplexed protein-DNA cross-linking: Scrunching in transcription start site selection. Science, 351, 2016
1SMY	Structural basis for transcription regulation by alarmone ppGpp 分子名称: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... 著者 Artsimovitch, I, Patlan, V, Sekine, S, Vassylyeva, M.N, Hosaka, T, Ochi, K, Yokoyama, S, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2004-03-10 公開日 2004-05-18 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural basis for transcription regulation by alarmone ppGpp Cell(Cambridge,Mass.), 117, 2004
6EEC	Mycobacterium tuberculosis RNAP promoter unwinding intermediate complex with RbpA/CarD and AP3 promoter captured by Corallopyronin 分子名称: DNA (63-MER), DNA (65-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J. 登録日 2018-08-13 公開日 2018-11-21 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.55 Å) 主引用文献 Structures of an RNA polymerase promoter melting intermediate elucidate DNA unwinding. Nature, 565, 2019
6EDT	Mycobacterium tuberculosis RNAP open promoter complex with RbpA/CarD and AP3 promoter 分子名称: DNA (65-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J. 登録日 2018-08-10 公開日 2018-11-21 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY 主引用文献 Structures of an RNA polymerase promoter melting intermediate elucidate DNA unwinding. Nature, 565, 2019
6EE8	Mycobacterium tuberculosis RNAP promoter unwinding intermediate complex with RbpA/CarD and AP3 promoter 分子名称: DNA (60-MER), DNA (65-MER), DNA-directed RNA polymerase subunit alpha, ... 著者 Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J. 登録日 2018-08-13 公開日 2018-11-21 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.92 Å) 主引用文献 Structures of an RNA polymerase promoter melting intermediate elucidate DNA unwinding. Nature, 565, 2019
7PP4	Cryo-EM structure of Mycobacterium tuberculosis RNA polymerase holoenzyme comprising sigma factor SigB 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Brodolin, K. 登録日 2021-09-13 公開日 2022-09-21 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (3.84 Å) 主引用文献 Structural basis of the mycobacterial stress-response RNA polymerase auto-inhibition via oligomerization Nat Commun, 14, 2023
6EYD	Structure of Mycobacterium smegmatis RNA polymerase Sigma-A holoenzyme 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Kouba, T, Barvik, I, Krasny, L. 登録日 2017-11-11 公開日 2018-12-12 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (4.22 Å) 主引用文献 The Core and Holoenzyme Forms of RNA Polymerase fromMycobacterium smegmatis. J. Bacteriol., 201, 2019
7Q4U	Cryo-EM structure of Mycobacterium tuberculosis RNA polymerase holoenzyme octamer comprising sigma factor SigB 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Brodolin, K. 登録日 2021-11-02 公開日 2022-11-16 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (4.39 Å) 主引用文献 Structural basis of the mycobacterial stress-response RNA polymerase auto-inhibition via oligomerization Nat Commun, 14, 2023

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