PDB: 326 件ウェブページステータス検索Chemie searchBIRD

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4Q5S	Thermus thermophilus RNA polymerase initially transcribing complex containing 6-mer RNA 分子名称: ADENOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*CP*CP*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*GP*CP*AP*GP*CP*CP*A)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G)-3'), ... 著者 Murakami, K.S. 登録日 2014-04-17 公開日 2014-07-09 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Structural basis of transcription initiation by bacterial RNA polymerase holoenzyme. J.Biol.Chem., 289, 2014
1SC5	Sigma-28(FliA)/FlgM complex 分子名称: RNA polymerase sigma factor FliA, anti-sigma factor FlgM 著者 Sorenson, M.K, Ray, S.S, Darst, S.A. 登録日 2004-02-11 公開日 2004-04-06 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (3.26 Å) 主引用文献 Crystal structure of the flagellar sigma/anti-sigma complex sigma(28)/FlgM reveals an intact sigma factor in an inactive conformation. Mol.Cell, 14, 2004
1SIG	CRYSTAL STRUCTURE OF A SIGMA70 SUBUNIT FRAGMENT FROM ESCHERICHIA COLI RNA POLYMERASE 分子名称: RNA POLYMERASE PRIMARY SIGMA FACTOR 著者 Malhotra, A, Severinova, E, Darst, S.A. 登録日 1997-02-18 公開日 1997-05-15 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystal structure of a sigma 70 subunit fragment from E. coli RNA polymerase. Cell(Cambridge,Mass.), 87, 1996
4Q4Z	Thermus thermophilus RNA polymerase de novo transcription initiation complex 分子名称: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, ADENOSINE-5'-TRIPHOSPHATE, DNA (25-MER), ... 著者 Murakami, K.S. 登録日 2014-04-15 公開日 2014-07-30 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Structural basis of transcription initiation by bacterial RNA polymerase holoenzyme. J.Biol.Chem., 289, 2014
8U3B	Cryo-EM structure of E. coli NarL-transcription activation complex at 3.2A 分子名称: DNA (69-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Liu, B, Kompaniiets, D, Wang, D. 登録日 2023-09-07 公開日 2024-01-17 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (3.23 Å) 主引用文献 Structural basis for transcription activation by the nitrate-responsive regulator NarL. Nucleic Acids Res., 52, 2024
7PP4	Cryo-EM structure of Mycobacterium tuberculosis RNA polymerase holoenzyme comprising sigma factor SigB 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Brodolin, K. 登録日 2021-09-13 公開日 2022-09-21 実験手法 ELECTRON MICROSCOPY (3.84 Å) 主引用文献 Structural basis of the mycobacterial stress-response RNA polymerase auto-inhibition via oligomerization Biorxiv, 2022
7Q4U	Cryo-EM structure of Mycobacterium tuberculosis RNA polymerase holoenzyme octamer comprising sigma factor SigB 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Brodolin, K. 登録日 2021-11-02 公開日 2022-11-16 最終更新日 2023-02-08 実験手法 ELECTRON MICROSCOPY (4.39 Å) 主引用文献 Structural basis of the mycobacterial stress-response RNA polymerase auto-inhibition via oligomerization Nat Commun, 14, 2023
7Q59	Cryo-EM structure of Mycobacterium tuberculosis RNA polymerase holoenzyme dimer comprising sigma factor SigB 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Brodolin, K. 登録日 2021-11-03 公開日 2022-11-16 最終更新日 2023-02-08 実験手法 ELECTRON MICROSCOPY (4.36 Å) 主引用文献 Structural basis of the mycobacterial stress-response RNA polymerase auto-inhibition via oligomerization Nat Commun, 14, 2023
8X6G	Cryo-EM structure of Staphylococcus aureus sigB-dependent RNAP-promoter open complex 分子名称: DNA (70-mer), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Yuan, L, Xu, L, Liu, Q, Feng, Y. 登録日 2023-11-21 公開日 2024-06-05 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structural basis of promoter recognition by Staphylococcus aureus RNA polymerase. Nat Commun, 15, 2024
8X6F	Cryo-EM structure of Staphylococcus aureus sigA-dependent RNAP-promoter open complex 分子名称: DNA (71-mer), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Yuan, L, Xu, L, Liu, Q, Feng, Y. 登録日 2023-11-21 公開日 2024-06-05 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Structural basis of promoter recognition by Staphylococcus aureus RNA polymerase. Nat Commun, 15, 2024
1RP3	Cocrystal structure of the flagellar sigma/anti-sigma complex, Sigma-28/FlgM 分子名称: RNA polymerase sigma factor SIGMA-28 (FliA), anti sigma factor FlgM 著者 Sorenson, M.K, Ray, S.S, Darst, S.A. 登録日 2003-12-02 公開日 2004-04-06 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal Structure of the Flagellar Sigma/Anti-Sigma Complex Sigma(28)/FlgM Reveals an Intact Sigma Factor in an Inactive Conformation Mol.Cell, 14, 2004
4OIN	Crystal structure of Thermus thermophilus transcription initiation complex soaked with GE23077 分子名称: (2Z)-2-methylbut-2-enoic acid, 5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*G)-3', 5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G)-3', ... 著者 Zhang, Y, Ebright, R.H, Arnold, E. 登録日 2014-01-20 公開日 2014-05-07 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 GE23077 binds to the RNA polymerase 'i' and 'i+1' sites and prevents the binding of initiating nucleotides. Elife, 3, 2014
8Z6G	the AlgU-MucAcyto complex structure in Pseudomonas aeruginosa 分子名称: Anti sigma-E RseA, N-terminal domain protein, RNA polymerase sigma factor 著者 Li, T, Wang, Y.Z, Bao, R. 登録日 2024-04-19 公開日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.10109687 Å) 主引用文献 the AlgU-MucAcyto complex structure in Pseudomonas aeruginosa To Be Published
4OIO	Crystal structure of Thermus thermophilus pre-insertion substrate complex for de novo transcription initiation 分子名称: 5'-D(*CP*CP*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3', 5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G)-3', 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, ... 著者 Zhang, Y, Ebright, R.H, Arnold, E. 登録日 2014-01-20 公開日 2014-05-07 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 GE23077 binds to the RNA polymerase 'i' and 'i+1' sites and prevents the binding of initiating nucleotides. Elife, 3, 2014
1SMY	Structural basis for transcription regulation by alarmone ppGpp 分子名称: DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... 著者 Artsimovitch, I, Patlan, V, Sekine, S, Vassylyeva, M.N, Hosaka, T, Ochi, K, Yokoyama, S, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) 登録日 2004-03-10 公開日 2004-05-18 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural basis for transcription regulation by alarmone ppGpp Cell(Cambridge,Mass.), 117, 2004
5H6X	The crystal structure of RpoS fragment including a partial region 1.2 and region 2 from intracellular pathogen Legionella pneumophila 分子名称: GLYCEROL, RNA polymerase sigma factor RpoS, SODIUM ION 著者 Zhang, N, Chen, X, Gong, X, Ge, H. 登録日 2016-11-15 公開日 2017-11-22 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 High-Resolution Crystal Structure of RpoS Fragment including a Partial Region 1.2 and Region 2 from the Intracellular Pathogen Legionella pneumophila Crystals, 8, 2018
5VO8	X-ray crystal structure of a bacterial reiterative transcription complex of pyrG promoter 分子名称: DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*CP*TP*GP*AP*TP*GP*CP*AP*CP*C)-3'), DNA (5'-D(P*GP*GP*TP*GP*CP*AP*TP*CP*AP*GP*AP*GP*CP*CP*CP*AP*AP*AP*A)-3'), DNA-directed RNA polymerase subunit alpha, ... 著者 Murakami, K.S, Shin, Y, Turnbough Jr, C.L, Molodtsov, V. 登録日 2017-05-02 公開日 2017-05-24 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 X-ray crystal structure of a reiterative transcription complex reveals an atypical RNA extension pathway. Proc. Natl. Acad. Sci. U.S.A., 114, 2017
5VT0	Escherichia coli 6S RNA derivative in complex with Escherichia coli RNA polymerase sigma70-holoenzyme 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Chen, J, Darst, S.A. 登録日 2017-05-15 公開日 2017-11-01 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.78 Å) 主引用文献 6S RNA Mimics B-Form DNA to Regulate Escherichia coli RNA Polymerase. Mol. Cell, 68, 2017
5VI5	Structure of Mycobacterium smegmatis transcription initiation complex with a full transcription bubble 分子名称: 1,2-ETHANEDIOL, DNA (44-MER), DNA (49-MER), ... 著者 Darst, S.A, Campbell, E.A, Lilic, M. 登録日 2017-04-14 公開日 2017-07-26 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (3.196 Å) 主引用文献 Structural insights into the mycobacteria transcription initiation complex from analysis of X-ray crystal structures. Nat Commun, 8, 2017
4ZH3	Crystal structure of Escherichia coli RNA polymerase in complex with CBRH16-Br 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Feng, Y, Ebright, R.H. 登録日 2015-04-24 公開日 2015-08-05 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (4.082 Å) 主引用文献 Structural Basis of Transcription Inhibition by CBR Hydroxamidines and CBR Pyrazoles. Structure, 23, 2015
5VSW	X-ray crystal structure of Escherichia coli RNA polymerase and DksA/ppGpp complex 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Murakami, K.S, Molodtsov, V. 登録日 2017-05-12 公開日 2017-06-14 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (4.295 Å) 主引用文献 Allosteric Effector ppGpp Potentiates the Inhibition of Transcript Initiation by DksA. Mol. Cell, 69, 2018
4ZH4	Crystal structure of Escherichia coli RNA polymerase in complex with CBRP18 分子名称: 5-(4-fluorophenyl)-4-[4-fluoro-3-(trifluoromethyl)phenyl]-1H-pyrazole, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Feng, Y, Ebright, R.H. 登録日 2015-04-24 公開日 2015-08-05 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.993 Å) 主引用文献 Structural Basis of Transcription Inhibition by CBR Hydroxamidines and CBR Pyrazoles. Structure, 23, 2015
5VI8	Structure of a mycobacterium smegmatis transcription initiation complex with an upstream-fork promoter fragment 分子名称: 1,2-ETHANEDIOL, DNA (26-MER), DNA (31-MER), ... 著者 Hubin, E.A, Campbell, E.A, Darst, S.A. 登録日 2017-04-14 公開日 2017-04-26 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.76 Å) 主引用文献 Structural insights into the mycobacteria transcription initiation complex from analysis of X-ray crystal structures. Nat Commun, 8, 2017
5IPN	SigmaS-transcription initiation complex with 4-nt nascent RNA 分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... 著者 Liu, B, Zuo, Y, Steitz, T.A. 登録日 2016-03-09 公開日 2016-03-30 最終更新日 2016-06-22 実験手法 X-RAY DIFFRACTION (4.61 Å) 主引用文献 Structures of E. coli sigma S-transcription initiation complexes provide new insights into polymerase mechanism. Proc.Natl.Acad.Sci.USA, 113, 2016
5IPL	SigmaS-transcription initiation complex with 4-nt nascent RNA 分子名称: DIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... 著者 Liu, B, Zuo, Y, Steitz, T.A. 登録日 2016-03-09 公開日 2016-03-30 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 Structures of E. coli sigma S-transcription initiation complexes provide new insights into polymerase mechanism. Proc.Natl.Acad.Sci.USA, 113, 2016

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