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7TDI
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Rabbit RyR1 with AMP-PCP and high Ca2+ embedded in nanodisc in closed-inactivated conformation class 2 (Dataset-A)
分子名称: CALCIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Ryanodine receptor 1,Ryanodine receptor 1,RyR1, ...
著者Nayak, A.R, Samso, M.
登録日2021-12-31
公開日2022-03-09
最終更新日2022-03-16
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Ca 2+ -inactivation of the mammalian ryanodine receptor type 1 in a lipidic environment revealed by cryo-EM.
Elife, 11, 2022
7TDG
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Rabbit RyR1 with AMP-PCP and high Ca2+ embedded in nanodisc in inactivated conformation (Dataset-A)
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CALCIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ...
著者Nayak, A.R, Samso, M.
登録日2021-12-31
公開日2022-03-09
最終更新日2022-03-16
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Ca 2+ -inactivation of the mammalian ryanodine receptor type 1 in a lipidic environment revealed by cryo-EM.
Elife, 11, 2022
7TDJ
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BU of 7tdj by Molmil
Rabbit RyR1 with AMP-PCP and high Ca2+ embedded in nanodisc in closed-inactivated conformation class 1(Dataset-A)
分子名称: CALCIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Ryanodine receptor 1,Ryanodine receptor 1,RyR1, ...
著者Nayak, A.R, Samso, M.
登録日2021-12-31
公開日2022-03-09
最終更新日2022-03-16
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Ca 2+ -inactivation of the mammalian ryanodine receptor type 1 in a lipidic environment revealed by cryo-EM.
Elife, 11, 2022
7T64
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BU of 7t64 by Molmil
Rabbit RyR1 disease mutant Y523S in complex with FKBP12.6 embedded in lipidic nanodisc in the closed state
分子名称: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ZINC ION
著者Iyer, K.A, Hu, Y, Murayama, T, Samso, M.
登録日2021-12-13
公開日2022-07-20
最終更新日2024-02-28
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Molecular mechanism of the severe MH/CCD mutation Y522S in skeletal ryanodine receptor (RyR1) by cryo-EM.
Proc.Natl.Acad.Sci.USA, 119, 2022
7T65
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BU of 7t65 by Molmil
Rabbit RyR1 disease mutant Y523S in complex with FKBP12.6 embedded in lipidic nanodisc in the open state
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ...
著者Iyer, K.A, Hu, Y, Murayama, T, Samso, M.
登録日2021-12-13
公開日2022-07-20
最終更新日2022-08-03
実験手法ELECTRON MICROSCOPY (4.05 Å)
主引用文献Molecular mechanism of the severe MH/CCD mutation Y522S in skeletal ryanodine receptor (RyR1) by cryo-EM.
Proc.Natl.Acad.Sci.USA, 119, 2022
7VMS
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BU of 7vms by Molmil
Structure of recombinant RyR2 mutant K4593A (Ca2+ dataset)
分子名称: CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ...
著者Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H.
登録日2021-10-09
公開日2022-08-10
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations
Nat Commun, 13, 2022
7VML
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BU of 7vml by Molmil
Structure of recombinant RyR2 (EGTA dataset, class 1&2, closed state)
分子名称: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION
著者Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H.
登録日2021-10-09
公開日2022-08-10
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations.
Nat Commun, 13, 2022
7VMO
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BU of 7vmo by Molmil
Structure of recombinant RyR2 (Ca2+ dataset, class 1, open state)
分子名称: CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ...
著者Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H.
登録日2021-10-09
公開日2022-08-10
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations.
Nat Commun, 13, 2022
7VMM
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BU of 7vmm by Molmil
Structure of recombinant RyR2 (EGTA dataset, class 1, closed state)
分子名称: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION
著者Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H.
登録日2021-10-09
公開日2022-08-10
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations.
Nat Commun, 13, 2022
7VMN
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BU of 7vmn by Molmil
Structure of recombinant RyR2 (EGTA dataset, class 2, closed state)
分子名称: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION
著者Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H.
登録日2021-10-09
公開日2022-08-10
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations.
Nat Commun, 13, 2022
7VMQ
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BU of 7vmq by Molmil
Structure of recombinant RyR2 (Ca2+ dataset, class 3, open state)
分子名称: CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ...
著者Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H.
登録日2021-10-09
公開日2022-08-10
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations
Nat Commun, 13, 2022
7VMR
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BU of 7vmr by Molmil
Structure of recombinant RyR2 mutant K4593A (EGTA dataset)
分子名称: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION
著者Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H.
登録日2021-10-09
公開日2022-08-10
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations.
Nat Commun, 13, 2022
7VMP
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BU of 7vmp by Molmil
Structure of recombinant RyR2 (Ca2+ dataset, class 2, open state)
分子名称: CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ...
著者Kobayashi, T, Tsutsumi, A, Kurebayashi, N, Kodama, M, Kikkawa, M, Murayama, T, Ogawa, H.
登録日2021-10-09
公開日2022-08-10
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations.
Nat Commun, 13, 2022
7M6L
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BU of 7m6l by Molmil
High resolution structure of the membrane embedded skeletal muscle ryanodine receptor
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, CALCIUM ION, ...
著者Melville, Z, Kim, K, Clarke, O.B, Marks, A.R.
登録日2021-03-25
公開日2021-08-18
最終更新日2022-01-19
実験手法ELECTRON MICROSCOPY (3.98 Å)
主引用文献High-resolution structure of the membrane-embedded skeletal muscle ryanodine receptor.
Structure, 30, 2022
7M6A
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BU of 7m6a by Molmil
High resolution structure of the membrane embedded skeletal muscle ryanodine receptor
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, CALCIUM ION, ...
著者Melville, Z, Kim, K, Clarke, O.B, Marks, A.R.
登録日2021-03-25
公開日2021-09-08
最終更新日2022-01-19
実験手法ELECTRON MICROSCOPY (3.36 Å)
主引用文献High-resolution structure of the membrane-embedded skeletal muscle ryanodine receptor.
Structure, 30, 2022
7CF9
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BU of 7cf9 by Molmil
Structure of RyR1 (Ca2+/CHL)
分子名称: 5-bromanyl-N-[4-chloranyl-2-methyl-6-(methylcarbamoyl)phenyl]-2-(3-chloranylpyridin-2-yl)pyrazole-3-carboxamide, CALCIUM ION, Peptidyl-prolyl cis-trans isomerase FKBP1B, ...
著者Ma, R, Haji-Ghassemi, O, Ma, D, Lin, L, Samurkas, A, Van Petegem, F, Yuchi, Z.
登録日2020-06-24
公開日2020-09-02
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Structural basis for diamide modulation of ryanodine receptor.
Nat.Chem.Biol., 16, 2020
6WOV
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BU of 6wov by Molmil
Cryo-EM structure of recombinant mouse Ryanodine Receptor type 2 wild type in complex with FKBP12.6
分子名称: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION
著者Iyer, K.A, Hu, Y, Nayak, A.R, Kurebayashi, N, Murayama, T, Samso, M.
登録日2020-04-25
公開日2020-08-05
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (5.1 Å)
主引用文献Structural mechanism of two gain-of-function cardiac and skeletal RyR mutations at an equivalent site by cryo-EM.
Sci Adv, 6, 2020
6WOU
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BU of 6wou by Molmil
Cryo-EM structure of recombinant mouse Ryanodine Receptor type 2 mutant R176Q in complex with FKBP12.6 in nanodisc
分子名称: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 2, ZINC ION
著者Iyer, K.A, Hu, Y, Kurebayashi, N, Murayama, T, Samso, M.
登録日2020-04-25
公開日2020-08-05
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.27 Å)
主引用文献Structural mechanism of two gain-of-function cardiac and skeletal RyR mutations at an equivalent site by cryo-EM.
Sci Adv, 6, 2020
6WOT
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BU of 6wot by Molmil
Cryo-EM structure of recombinant rabbit Ryanodine Receptor type 1 mutant R164C in complex with FKBP12.6
分子名称: Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine receptor 1, ZINC ION
著者Iyer, K.A, Hu, Y, Kurebayashi, N, Murayama, T, Samso, M.
登録日2020-04-25
公開日2020-08-05
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.54 Å)
主引用文献Structural mechanism of two gain-of-function cardiac and skeletal RyR mutations at an equivalent site by cryo-EM.
Sci Adv, 6, 2020
6M2W
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BU of 6m2w by Molmil
Structure of RyR1 (Ca2+/Caffeine/ATP/CaM1234/CHL)
分子名称: 5-bromanyl-N-[4-chloranyl-2-methyl-6-(methylcarbamoyl)phenyl]-2-(3-chloranylpyridin-2-yl)pyrazole-3-carboxamide, ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, ...
著者Ma, R, Haji-Ghassemi, O, Ma, D, Lin, L, Samurkas, A, Van Petegem, F, Yuchi, Z.
登録日2020-03-01
公開日2020-09-02
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural basis for diamide modulation of ryanodine receptor.
Nat.Chem.Biol., 16, 2020
6UHH
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BU of 6uhh by Molmil
Crystal Structure of Human RYR Receptor 3 ( 848-1055) in Complex with ATP
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, ...
著者Wu, R, Kim, Y, Jedrzejczak, R, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2019-09-27
公開日2020-08-05
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (3.138 Å)
主引用文献Crystal Structure of Human RYR Receptor 3 ( 848-1055) in Complex with ATP
To Be Published
6UHA
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BU of 6uha by Molmil
Open-form Crystal Structure of Human RYR Receptor 3 ( 848-1055)
分子名称: DI(HYDROXYETHYL)ETHER, Ryanodine receptor 3
著者Wu, R, Kim, Y, Jedrzejczak, R, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2019-09-27
公開日2020-08-05
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.855 Å)
主引用文献Open-form Crystal Structure of Human RYR Receptor 3 ( 848-1055)
To Be Published
6UHB
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BU of 6uhb by Molmil
Crystal Structure of Human RYR Receptor 3 (848-1055)
分子名称: GLYCEROL, PHOSPHATE ION, Ryanodine receptor 3
著者Wu, R, Joachimiak, A, Jedrzejczak, R, Midwest Center for Structural Genomics (MCSG)
登録日2019-09-27
公開日2020-08-05
実験手法X-RAY DIFFRACTION (2.504 Å)
主引用文献Crystal Structure of Human RYR Receptor 3 (848-1055)
To Be Published
6UHE
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BU of 6uhe by Molmil
Closed-form Crystal Structure of Human RYR Receptor 3 ( 848-1055)
分子名称: Ryanodine receptor 3
著者Wu, R, Kim, Y, Jedrzejczak, R, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2019-09-27
公開日2020-08-05
実験手法X-RAY DIFFRACTION (2.892 Å)
主引用文献Closed-form Crystal Structure of Human RYR Receptor 3 ( 848-1055)
To Be Published
6UHI
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BU of 6uhi by Molmil
Closed-form Crystal Structure of Chimera Bt-hRyR_12 from Bacteroides thetaiotaomicron /human
分子名称: GLYCEROL, Ryanodine receptor 1 chimera
著者Wu, R, Jedrzejczak, R, KIm, Y, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2019-09-27
公開日2020-09-16
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.88 Å)
主引用文献Closed-form Crystal Structure of Chimera Bt-hRyR_12 from Bacteroides thetaiotaomicron /human
to be published

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件を2024-06-12に公開中

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